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CEREBRAL
PALSY
by dr M Saleem Laghari
MBBS,MCPS,FCPS(GOLD MEDALIST)
Assistant professor
Paediatrics
DEFINITION
1. Disorder of Movement and posture
2. Damage to immature brain
3. Permanent
4. Non progressive (static encephalopathy)
5. Non hereditary
6. Onset before or at birth or during early months
of life.
INCIDENCE / PREVALENCE
• In the industrialized world, the incidence
of cerebral palsy is about 2 per 1000 live
births while in developing world is 7/1000
live births.
ETIOLOGY
Intrauterine
• Bleeding
• Infections such as rubella and
toxoplasmosis.
• Thromboembolic phenomena
• Congenital malformations:
Disorders of neuronal migration
• Massive irradiation
Peri natal and postnatal
• Birth trauma
• Intracerebral hemorrhage, cerebral
infarction.
• Birth asphyxia, hypoxic ischemic
encephalopathy.
• Hypoglycemia
• Kernicterus
• Acidosis
Infancy
• Meningitis,
• Encephalitis,
• Hypoglycemia
• Trauma
• Vascular accidents
Pathology
• Extent of pathological lesion variable
• Wide spread cerebral atrophy
• Atrophy of basal ganglia.
• Atrophy and gliosis of one or both cerebral
hemispheres
Clinical Types of cerebral palsy
• Spastic C. Palsy 75 %
• Extra pyramidal C.Palsy 9 to 22%
(Choreoathetosis, dystonia)
• Mixed cerebral palsy
• Atonic cerebral palsy
Atonic Diplegia
Cong.Cerebellar Ataxia
TOPOGRAPHIC CLASSIFICATION
• Monoplegia
• Paraplegia
• Hemiplegia
• Triplegia
• Quadriplegia
• Diplegia
FUCTIONAL CLASSIFICAITON
• CLASS 1 No limitation of actitivity
• CLASS ii Slight to moderate limitation
• CLASS III Moderate to great limitation
• CLASS IV No useful physical activity
Different forms of cerebral palsy
• Spastic diplegia (10 – 33%)
• Spastic quadriplegia (9-43%)
• Spastic hemiplegia (25-40%)
• Extrapyramidal CP (9-22%)
• Atonic CP
• Mixed CP (9-22%)
Clinical features
• Manifestation may not be apparent before
one year of age.
• Reflex hyperactivity
• Pseudobulbar palsy when spasticity is
bilateral.
• Excessive drooling.
• Microcephaly
Clinical features
• Delayed motor
milestones
• Decreased power
• Abnormality of tone
• Abnormal
Persistence of
primitive reflexes
 Moro reflex
• Paucity of movements and facial
expression
• Arching back
• Scissoring of legs and gait
• Clenching of hands with adducted
thumb
• Sustained Ankle Clonus
• Spastic gait
• Clasp knife type spasticity
• Exaggerated deep tendon
reflexes
• Delayed / slurred speech
• Choreo athetosis
• Ataxia
• Babinski sign positive after
the age of two years.
COMPLICATIONS AND
ASSOCIATED DEFICITS
• Seizure disorders 50%
• Mental retardation 50%
• Visual defects 50%
• Microcephaly 25%
• Hearing defects 15%
• Speech Disorders 15%
• Psychological problems
• Learning problems
• Behavior problems
• Psychiatric
problems
• Secondary
contracture and
deformities
• Constipation
• Oro dental infections
• Recurrent SOM
• Recurrent aspiration
• Recurrent UTI
• Bed sores
Differential Diagnosis
• Leukodystrophy
• Hydrocephalus / subdural effusion
• Brain tumor
• Spinal cord lesions
• Muscular dystrophy
• Werdnig hoffmann and benign congenital
hypotonia
• Progressive CNS disorder
INVESTIGATIONS
• C.T. Scan Brain
• M.R.I.Brain
• EEG
• IQ testing
• Audiometry
• Visual assessment
• Investigations for
complications
MANAGEMENT
 The disease is
incurable.
 AIM is to make child
more functional and
independent.
 Multi disciplinary approach.
PHYSIOTHERAPY
• Passive
movements to all
the limbs.
• Prone position
• Keep legs apart
with pillow in
between while
sleeping.
• Stretching
exercises to
prevent
contractures.
• Help the baby to learn
and maintain sitting
posture
• Teach the baby to hold
his head and balance it
• Teach baby to use
hands by grasping and
relaxing, use soft ball or
rubber toy.
• Turn him frequently
from supine to prone
and vice versa
• Teach him to
crawl.
• Help him to stand
and walk
• Use walking aids
when necessary.
• Correct application
of splints and
braces
• Protection from
injuries and
infections.
 Teach necessary skills
for daily life;
feeding, dressing, toilet
training, speech, writing
etc.
 Provide recreational
facilities like
games, cycling,swimmi
ng etc.
• Take care of the
child's education
and find out the
appropriate
institution and
occupation
Vision and hearing
i) Perform careful assessment of vision
and hearing
ii) Seek help of ophthalmologist for squints
and errors of refraction
iii) Refer for audiometry and guidance for
hearing aids.
Speech and feeding
1. Give feeding and speech advise
2. Advise more frequent and small feeds, to
prevent malnutrition.
3. Give more time for chewing and
swallowing
4. Provide constant stimulation of hearing
to help the development of speech
Orthopedic advise
1. Advice for boots and shoes
2. Surgical help for elongation of tendo
calcaneus.
3. Surgical procedure for reduction of
adduction spasm
4. Tendon transfer procedures to help
supination and pronation.
5. Division of spinal nerves for severe
spasticity.
PSYCHIATRIC HELP
For behavior disturbance
EPILEPSY
Anticonvulsants
SPASTICITY
Diazepam, baclofen, benzhexol and
Inj. of botulin toxin into posterior nerve
roots
Prevention
• Pre natal care.
• Natal care.
• Post natal care.
Prognosis
• Depends on presence and severity of
associated motor and intellectual
handicap.
Cerebral palsy

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Cerebral palsy

  • 1. CEREBRAL PALSY by dr M Saleem Laghari MBBS,MCPS,FCPS(GOLD MEDALIST) Assistant professor Paediatrics
  • 2. DEFINITION 1. Disorder of Movement and posture 2. Damage to immature brain 3. Permanent 4. Non progressive (static encephalopathy) 5. Non hereditary 6. Onset before or at birth or during early months of life.
  • 3. INCIDENCE / PREVALENCE • In the industrialized world, the incidence of cerebral palsy is about 2 per 1000 live births while in developing world is 7/1000 live births.
  • 4. ETIOLOGY Intrauterine • Bleeding • Infections such as rubella and toxoplasmosis. • Thromboembolic phenomena • Congenital malformations: Disorders of neuronal migration • Massive irradiation
  • 5. Peri natal and postnatal • Birth trauma • Intracerebral hemorrhage, cerebral infarction. • Birth asphyxia, hypoxic ischemic encephalopathy. • Hypoglycemia • Kernicterus • Acidosis
  • 6. Infancy • Meningitis, • Encephalitis, • Hypoglycemia • Trauma • Vascular accidents
  • 7. Pathology • Extent of pathological lesion variable • Wide spread cerebral atrophy • Atrophy of basal ganglia. • Atrophy and gliosis of one or both cerebral hemispheres
  • 8. Clinical Types of cerebral palsy • Spastic C. Palsy 75 % • Extra pyramidal C.Palsy 9 to 22% (Choreoathetosis, dystonia) • Mixed cerebral palsy • Atonic cerebral palsy Atonic Diplegia Cong.Cerebellar Ataxia
  • 9. TOPOGRAPHIC CLASSIFICATION • Monoplegia • Paraplegia • Hemiplegia • Triplegia • Quadriplegia • Diplegia
  • 10. FUCTIONAL CLASSIFICAITON • CLASS 1 No limitation of actitivity • CLASS ii Slight to moderate limitation • CLASS III Moderate to great limitation • CLASS IV No useful physical activity
  • 11. Different forms of cerebral palsy • Spastic diplegia (10 – 33%) • Spastic quadriplegia (9-43%) • Spastic hemiplegia (25-40%) • Extrapyramidal CP (9-22%) • Atonic CP • Mixed CP (9-22%)
  • 12. Clinical features • Manifestation may not be apparent before one year of age. • Reflex hyperactivity • Pseudobulbar palsy when spasticity is bilateral. • Excessive drooling. • Microcephaly
  • 13. Clinical features • Delayed motor milestones • Decreased power • Abnormality of tone • Abnormal Persistence of primitive reflexes  Moro reflex
  • 14. • Paucity of movements and facial expression • Arching back • Scissoring of legs and gait • Clenching of hands with adducted thumb • Sustained Ankle Clonus
  • 15. • Spastic gait • Clasp knife type spasticity • Exaggerated deep tendon reflexes • Delayed / slurred speech • Choreo athetosis • Ataxia • Babinski sign positive after the age of two years.
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  • 20. COMPLICATIONS AND ASSOCIATED DEFICITS • Seizure disorders 50% • Mental retardation 50% • Visual defects 50% • Microcephaly 25% • Hearing defects 15% • Speech Disorders 15% • Psychological problems
  • 21. • Learning problems • Behavior problems • Psychiatric problems • Secondary contracture and deformities • Constipation
  • 22. • Oro dental infections • Recurrent SOM • Recurrent aspiration • Recurrent UTI • Bed sores
  • 23. Differential Diagnosis • Leukodystrophy • Hydrocephalus / subdural effusion • Brain tumor • Spinal cord lesions • Muscular dystrophy • Werdnig hoffmann and benign congenital hypotonia • Progressive CNS disorder
  • 24. INVESTIGATIONS • C.T. Scan Brain • M.R.I.Brain • EEG • IQ testing • Audiometry • Visual assessment • Investigations for complications
  • 25. MANAGEMENT  The disease is incurable.  AIM is to make child more functional and independent.
  • 28. • Prone position • Keep legs apart with pillow in between while sleeping. • Stretching exercises to prevent contractures.
  • 29. • Help the baby to learn and maintain sitting posture • Teach the baby to hold his head and balance it • Teach baby to use hands by grasping and relaxing, use soft ball or rubber toy. • Turn him frequently from supine to prone and vice versa
  • 30. • Teach him to crawl. • Help him to stand and walk • Use walking aids when necessary. • Correct application of splints and braces • Protection from injuries and infections.
  • 31.  Teach necessary skills for daily life; feeding, dressing, toilet training, speech, writing etc.  Provide recreational facilities like games, cycling,swimmi ng etc.
  • 32. • Take care of the child's education and find out the appropriate institution and occupation
  • 33. Vision and hearing i) Perform careful assessment of vision and hearing ii) Seek help of ophthalmologist for squints and errors of refraction iii) Refer for audiometry and guidance for hearing aids.
  • 34. Speech and feeding 1. Give feeding and speech advise 2. Advise more frequent and small feeds, to prevent malnutrition. 3. Give more time for chewing and swallowing 4. Provide constant stimulation of hearing to help the development of speech
  • 35. Orthopedic advise 1. Advice for boots and shoes 2. Surgical help for elongation of tendo calcaneus. 3. Surgical procedure for reduction of adduction spasm 4. Tendon transfer procedures to help supination and pronation. 5. Division of spinal nerves for severe spasticity.
  • 36. PSYCHIATRIC HELP For behavior disturbance EPILEPSY Anticonvulsants SPASTICITY Diazepam, baclofen, benzhexol and Inj. of botulin toxin into posterior nerve roots
  • 37. Prevention • Pre natal care. • Natal care. • Post natal care.
  • 38. Prognosis • Depends on presence and severity of associated motor and intellectual handicap.