Lecture Notes For Medical Students.

1. MCQ
• Crohn's disease –
a) Continous involvement
b) Sinus & fistula
c) Mesenteric lymphadenitis
d) Stud ulcer

2. MCQ
• Crohn's disease –
a) Continous involvement
b) Sinus & fistula
c) Mesenteric lymphadenitis
d) Stud ulcer

3. Teaching Point
• Stud ullcer or collar stud/button ulcer are seen in ulcerative
colitis

4. MCQ
• 178.In a 27 yr old male most common cause of a colo-
vesical fistula would be:--AI 2001
A. Crohns disease
B. Ulcerative colitis
C. TB
D. Cancer colon

5. MCQ
• 178.In a 27 yr old male most common cause of a colo-
vesical fistula would be:--AI 2001
A. Crohns disease
B. Ulcerative colitis
C. TB
D. Cancer colon

6. MCQ
• Skip lesions are seen in: AIIMS May 2009
A. Ulcerative colitis
B. Crohn's disease
C. Typhoid
D. Tuberculosis

7. MCQ
• Skip lesions are seen in: AIIMS May 2009
A. Ulcerative colitis
B. Crohn's disease
C. Typhoid
D. Tuberculosis

8. MCQ
• Mouth ulcers are more common in
A. Diverticular disease
B. Coeliac disease
C. Solitary ulcer of rectum
D. Ulcerative colitis
E. Crohn’s disease

9. MCQ
• Mouth ulcers are more common in
A. Diverticular disease
B. Coeliac disease
C. Solitary ulcer of rectum
D. Ulcerative colitis
E. Crohn’s disease

10. MCQ
• Crohn’s disease affects the lips:
A. Rarely
B. Sometimes
C. Frequently
D. Never
E. Invariably

11. MCQ
• Crohn’s disease affects the lips:
A. Rarely
B. Sometimes
C. Frequently
D. Never
E. Invariably

12. MCQ
• True statements about inflammatory bewel disease Surgery is the 1st
management
A. Pouch operation is done for fulminant ulcerative colitis
B. 2 % case of chrons disease undergo malignant changes
C. Ulcerative colitis don't undergo malignant Changes
D. e.none

13. MCQ
• True statements about inflammatory bewel disease Surgery is the 1st
management
A. Pouch operation is done for fulminant ulcerative colitis
B. 2 % case of chrons disease undergo malignant changes
C. Ulcerative colitis don't undergo malignant Changes
D. e.none

14. MCQ
• 1%. String sign of Kantor seen in?
A. Crohn's disease
B. Ulcerative colitis
C. Both
D. None

15. MCQ
• 1%. String sign of Kantor seen in?
A. Crohn's disease
B. Ulcerative colitis
C. Both
D. None

16. MCQ
• A patient with Crohn's disease was opened
for and an inflammed appendix found.
The treatment of choice is-
A. Appendicectomy (PGI 88)
B. Ileocolic resection and anastamosis
C. Close the abdomen and start medical treatment
D. None of the above

17. MCQ
• A patient with Crohn's disease was opened
for and an inflammed appendix found.
The treatment of choice is-
A. Appendicectomy (PGI 88)
B. Ileocolic resection and anastamosis
C. Close the abdomen and start medical treatment
D. None of the above

18. MCQ
• Skin lesions with tuberculoid granulomas is characteristic of -
A. Hodgkins lymphoma-
B. Sarcoidosis
C. Crohns disease
D. Ulcerative colitis

19. MCQ
• Skin lesions with tuberculoid granulomas is characteristic of -
A. Hodgkins lymphoma-
B. Sarcoidosis
C. Crohns disease
D. Ulcerative colitis

20. MCQ
• False regarding invlovement in Crohn's disease -
A. Anorectal area (AIIMS 94)
B. Rectum
C. Small intestine with Rt. colon
D. Large intestine alone without involvement of small intestine

21. MCQ
• False regarding invlovement in Crohn's disease -
A. Anorectal area (AIIMS 94)
B. Rectum
C. Small intestine with Rt. colon
D. Large intestine alone without involvement of small intestine

22. MCQ
• In a 27 yr old male most common cause of a colovesical fistula would be - (AI 01, AI
99)
A. Crohns disease
B. Ulcerative colitis
C. TB
D. Cancer colon

23. MCQ
• In a 27 yr old male most common cause of a colovesical fistula would be - (AI 01, AI
99)
A. Crohns disease
B. Ulcerative colitis
C. TB
D. Cancer colon

24. MCQ
• Most common cause of death in Crohn's disease is due to: (AIIMS MAY 09)
A. Sepsis
B. Thromboembolic complication
C. Electrolyte disturbance
D. Malignancy

25. MCQ
• Most common cause of death in Crohn's disease is due to: (AIIMS MAY 09)
A. Sepsis
B. Thromboembolic complication
C. Electrolyte disturbance
D. Malignancy

26. MCQ
• A patient gives chronic history of diarrhoea
and blood in stool presents with multiple
fistulae in the perineum and multiple
stricture in small intestine. The diagnosis is
- (AIIMS JUNE 2000)
A. Crohn's disease
B. Radiation enteritis
C. Ulcerative Colitis
D. Ischemic bowel disease

27. MCQ
• A patient gives chronic history of diarrhoea
and blood in stool presents with multiple
fistulae in the perineum and multiple
stricture in small intestine. The diagnosis is
- (AIIMS JUNE 2000)
A. Crohn's disease
B. Radiation enteritis
C. Ulcerative Colitis
D. Ischemic bowel disease

28. MCQ
• In Crohn's disease all are seen except :
[PGI DEC 06]
A. Hyperplastic polyps
B. Diverticulosis
C. Fissuring ulcer
D. Epitheloid granuloma
E. Crypt abscess

29. MCQ
• In Crohn's disease all are seen except :
[PGI DEC 06]
A. Hyperplastic polyps
B. Diverticulosis
C. Fissuring ulcer
D. Epitheloid granuloma
E. Crypt abscess

30. MCQ
• Crohn's disease is associated with following
(D 96)
A. Stomach not involved
B. No granulomatous + Transmucosal fissures
C. Continuous involvement
D. Through and through involvement of
thickness of bowel wall

31. MCQ
• Crohn's disease is associated with following
(D 96)
A. Stomach not involved
B. No granulomatous + Transmucosal fissures
C. Continuous involvement
D. Through and through involvement of
thickness of bowel wall

32. MCQ
• Transmular inflammation with skip lesions in colon are
characteristric of – (AIIMS NOV 93)
A. Regional ileitis (crohn’s disease
B. Ischemic colitis
C. Ulcerative colitis
D. Non specific colitis

33. MCQ
• Transmular inflammation with skip lesions in colon are
characteristric of – (AIIMS NOV 93)
A. Regional ileitis (crohn’s disease
B. Ischemic colitis
C. Ulcerative colitis
D. Non specific colitis

34. MCQ
• Ulcerative colitis involves - (PGI DEC
01)
A. Serosa
B. Lamina propria
C. Mucosa
D. Circularis muscle
E. Submucosa

35. MCQ
• Ulcerative colitis involves - (PGI DEC
01)
A. Serosa
B. Lamina propria
C. Mucosa
D. Circularis muscle
E. Submucosa

36. MCQ
• In a 27-year-old male most common cause
of a colovesical fistula: (LB24th/1169-70)
(AI/2001)
A. Crohn's disease
B. Ulcerative colitis
C. TB
D. Cancer colon

37. MCQ
• In a 27-year-old male most common cause
of a colovesical fistula: (LB24th/1169-70)
(AI/2001)
A. Crohn's disease
B. Ulcerative colitis
C. TB
D. Cancer colon

38. MCQ
• Extraintestinal complication which is in
ulcerative colitis than Crohn's disease:
(LB24th / 1166) (PGI 93)
A. Uveitis
B. Pyoderma gangrenosum
C. Cirrhosis
D. Cholangiocarcinoma

39. MCQ
• Extraintestinal complication which is in
ulcerative colitis than Crohn's disease:
(LB24th / 1166) (PGI 93)
A. Uveitis
B. Pyoderma gangrenosum
C. Cirrhosis
D. Cholangiocarcinoma

40. MCQ
• Epitheloid like giant cells are seen in all of
the following except
A. Crohn's disease
B. Brucellosis
C. Leprosy
D. Ulcerative colitis (JI P - 1993)

41. MCQ
• Epitheloid like giant cells are seen in all of
the following except
A. Crohn's disease
B. Brucellosis
C. Leprosy
D. Ulcerative colitis (JI P - 1993)

42. Teaching Point
75/ sn chugh
Microscopically, non-caseating granulomas
are characteristic of Crohn's disease. These
granuloma consists of focal aggregates of
histiocytes surrounded by lymphocytes and
giant cells. Lymphoid aggregates or
microgranulomas are also seen which may
ulcerate on the surface of mucosa to form tiny
aphthous like ulcers.

43. MCQ
• Skip transmural lesions with tuberculoid
granuloma seen in: (LB24th/1169) (AIIMS
94)
A. Ulcerative colitis
B. Crohn's
C. Tuberculosis
D. Amoebiasis

44. MCQ
• Skip transmural lesions with tuberculoid
granuloma seen in: (LB24th/1169) (AIIMS
94)
A. Ulcerative colitis
B. Crohn's
C. Tuberculosis
D. Amoebiasis

45. Teaching Point
• Crohn's disease is a chronic transmural
inflammatory disease of the Gastrointestinal
tract of unknown aetiology.
• There are skip areas which are characteristic
of Crohn' s disease (one segment of intestine
is normal in between).
Microscopically, non-caseating granulomas
are characteristic of Crohn's disease. These
granuloma consists of focal aggregates of
histiocytes surrounded by lymphocytes and
giant cells.

46. MCQ
• False regarding involvement in Crohn's
disease: (LB24th / 1169) (AIIMS 94)
A. Anorectal area
B. Rectum
C. Small intestine with right colon
D. Large intestine alone without involvement of
small intestine

47. MCQ
• False regarding involvement in Crohn's
disease: (LB24th / 1169) (AIIMS 94)
A. Anorectal area
B. Rectum
C. Small intestine with right colon
D. Large intestine alone without involvement of
small intestine

48. Teaching Point
• 75/SN CHUGH/
• common sites of involvement in Crohn's
disease are terminal ileum and right side of
colon, followed by ileum alone, colon alone
or ileum and jejunum.

49. MCQ
• A patient with 8 year history of diarrhoea
and blood in stool presents with multiple
fistulae in perineum,was evaluated and
found to have multiple strictures in small
intestine, most likely cause is:(LB24Th
/1169) (AIIMS 2000)
A. Ulcerative colitis
B. Crohn's disease
C. Ischemic bowel disease
D. Radiation enteritis

50. MCQ
• A patient with 8 year history of diarrhoea
and blood in stool presents with multiple
fistulae in perineum,was evaluated and
found to have multiple strictures in small
intestine, most likely cause is:(LB24Th
/1169) (AIIMS 2000)
A. Ulcerative colitis
B. Crohn's disease
C. Ischemic bowel disease
D. Radiation enteritis

51. MCQ
• The sulfonamide used for chronic bowel
inflammatory disease is: (LB24th/1166)
(AIIMS 89)
A. Sulfapyridine
B. Sulfadiazine
C. Sulfasalazine
D. Sulfamethoxazole

52. MCQ
• The sulfonamide used for chronic bowel
inflammatory disease is: (LB24th/1166)
(AIIMS 89)
A. Sulfapyridine
B. Sulfadiazine
C. Sulfasalazine
D. Sulfamethoxazole

53. MCQ
• The extra-intestinal complication which is
seen more often in Ulcerative colitis than in
crohn's disease is
A. Pyoderma gangrenosum
B. Cholangiocarcinoma
C. Uveitis
D. Cirrhosis • (PGI - 1993)

54. MCQ
• The extra-intestinal complication which is
seen more often in Ulcerative colitis than in
crohn's disease is
A. Pyoderma gangrenosum
B. Cholangiocarcinoma
C. Uveitis
D. Cirrhosis • (PGI - 1993)

55. MCQ
• Skip lesions with tuberculoid granuloma is
seen in
A. Sarcoidosis
B. Hodgkins diease
C. Ulcerative colitis
D. Crohn's disease (AIIMS-1991)

56. MCQ
• Skip lesions with tuberculoid granuloma is
seen in
A. Sarcoidosis
B. Hodgkins diease
C. Ulcerative colitis
D. Crohn's disease (AIIMS-1991)

57. MCQ
• Skip lesions are seen in: aiims pgmee
questions — May 2009 /11page Ulcerative
colitis
A. Crohn's disease
B. Typhoid
C. Tuberculosis

58. MCQ
• Skip lesions are seen in: aiims pgmee
questions — May 2009 /11page Ulcerative
colitis
A. Crohn's disease
B. Typhoid
C. Tuberculosis

59. MCQ
• Most common cause of death in Crohn's
disease is due to: aiims pgmee questions —
May 2009 /11page Sepsis
A. Thromboembolic complication
B. Electrolyte disturbance
C. Malignancy

60. MCQ
• Most common cause of death in Crohn's
disease is due to: aiims pgmee questions —
May 2009 /11page Sepsis
A. Thromboembolic complication
B. Electrolyte disturbance
C. Malignancy

61. MCQ
• The most frequent indication for surgery in
Crohn's disease is
A. Abdominal mass
B. External fistula
C. Intestinal obstruction
D. Internal fistula

62. MCQ
• The most frequent indication for surgery in
Crohn's disease is
A. Abdominal mass
B. External fistula
C. Intestinal obstruction
D. Internal fistula

63. MCQ
• Skip lesions are characteristic of
A. Ulcerative colitis
B. Tropical sprue
C. Crohn's disease
D. Typhoid

64. MCQ
• Skip lesions are characteristic of
A. Ulcerative colitis
B. Tropical sprue
C. Crohn's disease
D. Typhoid

65. MCQ
• Which of the following is the earliest
radiological evidence of Crohn's disease?
A. Straightening of valvulae conniventes
B. Cobblestone.reticulation
C. Hyperperistalsis
D. String sign of kantor

66. MCQ
• Which of the following is the earliest
radiological evidence of Crohn's disease?
A. Straightening of valvulae conniventes
B. Cobblestone.reticulation
C. Hyperperistalsis
D. String sign of kantor

67. MCQ
• Hose pipe appearance of small bowel is
seen in
A. Ulcerative colitis
B. Lymphoma
C. Crohn's disease
D. All of the above

68. MCQ
• Hose pipe appearance of small bowel is
seen in
A. Ulcerative colitis
B. Lymphoma
C. Crohn's disease
D. All of the above

69. Teaching Point
• Manipal 466/ 2nd ed
• There is extensive inflammatory oedema and
mucosal ulcers are present. Fibrotic
thickening of the intestines results in Hose
Pipe Rigidity of the intestine.

70. MCQ
• Changes of Crohn's disease are most
prominent in
A. Duodenum
B. Jejunum
C. Ileum
D. Caecum

71. MCQ
• Changes of Crohn's disease are most
prominent in
A. Duodenum
B. Jejunum
C. Ileum
D. Caecum

72. MCQ
• Following are features of Crohn's disease
except
A. Fleshy lymphadenopathy
B. Skip lesions
C. Caseating granulomas
D. Transmural inflammation

73. MCQ
• Following are features of Crohn's disease
except
A. Fleshy lymphadenopathy
B. Skip lesions
C. Caseating granulomas
D. Transmural inflammation

74. Teaching Point
Sn chugh /75
Microscopically,
non-caseating granulomas are characteristic of
Crohn's disease. These granuloma consists of
focal aggregates of histiocytes surrounded by
lymphocytes and giant cells. Lymphoid
aggregates or microgranulomas are also seen
which may ulcerate on the surface of mucosa
to form tiny aphthous like ulcers.

75. MCQ
• Following are more often seen in Crohns
disease as compared to Ulcerative colitis
except
A. Perianal complications
B. Intestinal obstruction
C. Intestinal perforation
D. Toxic megacolon

76. MCQ
• Following are more often seen in Crohns
disease as compared to Ulcerative colitis
except
A. Perianal complications
B. Intestinal obstruction
C. Intestinal perforation
D. Toxic megacolon

77. MCQ
• Following conditions mimick linitis plastica
of stomach except
A. Syphilis
B. Sarcoidosis
C. Crohn's disease
D. Gardner's syndrome

78. MCQ
• Following conditions mimick linitis plastica
of stomach except
A. Syphilis
B. Sarcoidosis
C. Crohn's disease
D. Gardner's syndrome

79. MCQ
• Most common cause of colonic fistula in
India at age of 27 years:
A. Crohn's disease (UP 08)
B. Ulcerative colitis
C. Tuberculosis
D. Carcinoma rectum

80. MCQ
• Most common cause of colonic fistula in
India at age of 27 years:
A. Crohn's disease (UP 08)
B. Ulcerative colitis
C. Tuberculosis
D. Carcinoma rectum

81. MCQ
• Parenteral nutrition is not used in: (PGI
June 08)
A. Enterocutaneous fistula
B. Burns
C. Crohn's disease
D. ILEUS
E. Pancreatitis

82. MCQ
• Parenteral nutrition is not used in: (PGI
June 08)
A. Enterocutaneous fistula
B. Burns
C. Crohn's disease
D. ILEUS
E. Pancreatitis

83. MCQ
• A patient gives chronic history of Diarrhoea
an blood in stool presents with multiple
fistulae in the perineum and multiple
stricture in small intestine. Th diagnosis is -
-------9.12 / aiims pgmee questions June,
2000
A. Crohn's disease
B. Radiation enteritis
C. Ulcerative Colitis
D. Ischemic bowel disease

84. MCQ
• A patient gives chronic history of Diarrhoea
an blood in stool presents with multiple
fistulae in the perineum and multiple
stricture in small intestine. Th diagnosis is -
-------9.12 / aiims pgmee questions June,
2000
A. Crohn's disease
B. Radiation enteritis
C. Ulcerative Colitis
D. Ischemic bowel disease

85. MCQ
• Duodenal stricture is caused by -----
3.55aaaII (PG102)
A. Amoebiasis
B. T.B.
C. Ca pancreas
D. Crohns disease
E. Giardiasis

86. MCQ
• Duodenal stricture is caused by -----
3.55aaaII (PG102)
A. Amoebiasis
B. T.B.
C. Ca pancreas
D. Crohns disease
E. Giardiasis

87. MCQ
• Skip lesions with tuberculoid granulomas is
characteristic of----- 3.72aaaII (AIIMS 91)
A. Hodgkins lymphoma
B. -Sarcoidosis
C. Crohns disease
D. Ulcerative colitis

88. MCQ
• Skip lesions with tuberculoid granulomas is
characteristic of----- 3.72aaaII (AIIMS 91)
A. Hodgkins lymphoma
B. -Sarcoidosis
C. Crohns disease
D. Ulcerative colitis

89. MCQ
• False regarding invlovement in crohn's
disease---3.73aaaII (AIIMS 94)
A. Anorectal area
B. Rectum
C. Small intestine with Rt. colon
D. Large intestine alone without involvement Of
small intestine

90. MCQ
• False regarding invlovement in crohn's
disease---3.73aaaII (AIIMS 94)
A. Anorectal area
B. Rectum
C. Small intestine with Rt. colon
D. Large intestine alone without involvement Of
small intestine

91. MCQ
• Skip transmural lesions with tubercuooid
granuloma seen in ----3.73aaa II (AIIMS
94)
A. Ulcerative colitis
B. Crohn's
C. Tuberculosis
D. Amoebiasis

92. MCQ
• Skip transmural lesions with tubercuooid
granuloma seen in ----3.73aaa II (AIIMS
94)
A. Ulcerative colitis
B. Crohn's
C. Tuberculosis
D. Amoebiasis

93. MCQ
• Predisposing factors for colon ca are----
3.76aaaII (PG102)
A. Animal fat consumption
B. Familial adenomatous polyposis
C. Ulcerative colitis
D. Crohn's disease
E. TB

94. MCQ
• Predisposing factors for colon ca are----
3.76aaaII (PG102)
A. Animal fat consumption
B. Familial adenomatous polyposis
C. Ulcerative colitis
D. Crohn's disease
E. TB

95. MCQ
• True statements about inflammatory bowel
disease (IBD)----3.76aaaII (PGI 03)
A. Surgery is the 1st management
B. Pouch operation is done for fulminant
ulcerative colitis
C. 2 % case of chrons disease undergo malignant
changes
D. Ulcerative colitis don't undergo malignant
changes

96. MCQ
• True statements about inflammatory bowel
disease (IBD)----3.76aaaII (PGI 03)
A. Surgery is the 1st management
B. Pouch operation is done for fulminant
ulcerative colitis
C. 2 % case of chrons disease undergo malignant
changes
D. Ulcerative colitis don't undergo malignant
changes

97. MCQ
• "Cobblestone" appearance seen on
colonoscope is characteristic of the
following disease ----3.77 aaa II (MAHE
05)
A. Crohn's disease
B. Ulcerative colitis
C. TB colitis
D. Irritable bowel syndrome

98. MCQ
• "Cobblestone" appearance seen on
colonoscope is characteristic of the
following disease ----3.77 aaa II (MAHE
05)
A. Crohn's disease
B. Ulcerative colitis
C. TB colitis
D. Irritable bowel syndrome

99. Teaching Point
• MANIPAL /467/2ND ED
• INVESTIGATIONS
Cobble stone reticulation because of
multiple ulcers and islands of normal mucosa
in between.

100. MCQ
• Inflammatory bowel disease found in
children ----3.79aaaII
A. Ulcerative colitis (PGI June 06)
B. Tropical sprue
C. Crohn's disease
D. Celiac disease
E. Cystic fibrosis

101. MCQ
• Inflammatory bowel disease found in
children ----3.79aaaII
A. Ulcerative colitis (PGI June 06)
B. Tropical sprue
C. Crohn's disease
D. Celiac disease
E. Cystic fibrosis

102. MCQ
• A patient with Crohn's disease was opened
for and an Inflammed appendix found.
Treatment of choice is - ---3.82aaaII
(PG188)
A. Appendicectomy
B. Ileocolic resection and anastamosis
C. Close adbomen and start medical treatment
D. None of the above

103. MCQ
• A patient with Crohn's disease was opened
for and an Inflammed appendix found.
Treatment of choice is - ---3.82aaaII
(PG188)
A. Appendicectomy
B. Ileocolic resection and anastamosis
C. Close adbomen and start medical treatment
D. None of the above

104. MCQ
• Epitheloid like giant cells are seen in all
following except ----1.5aaaII (JIPMER 93)
A. Leprosy
B. Ulcerative Colitis
C. Crohns disease
D. Brucellosis

105. MCQ
• Epitheloid like giant cells are seen in all
following except ----1.5aaaII (JIPMER 93)
A. Leprosy
B. Ulcerative Colitis
C. Crohns disease
D. Brucellosis

106. MCQ
• All of following are precancerous except --
1.37aaaII(UPSC 88)
A. Ulcerative colitis
B. Pigmentary ciirhosis
C. Polyposis coli
D. Crohns disease
E. None

107. MCQ
• All of following are precancerous except --
1.37aaaII(UPSC 88)
A. Ulcerative colitis
B. Pigmentary ciirhosis
C. Polyposis coli
D. Crohns disease
E. None

108. Teaching Point
• LOVE BAILEY/ 1168 /24TH ED
• As with ulcerative colitis it is now believed
that Crohn's disease can predispose to
cancer, although the incidence of malignant
change is not nearly as high as in ulcerative
colitis and is most manifest in ileum.

109. MCQ
• Features of crohns disease are all except --
1.37aaaII
A. Lymphoid hyperplasia (JIPMER 91)
B. Skip lesion
C. Transmural involvement
D. Crypt Abscess

110. MCQ
• Features of crohns disease are all except --
1.37aaaII
A. Lymphoid hyperplasia (JIPMER 91)
B. Skip lesion
C. Transmural involvement
D. Crypt Abscess

111. MCQ
• Transmural involvement & granuloma are
seen in --1.37aaaII (JIPMER 98)
A. Ulcerative coilitis
B. Crohn's disease
C. Tropical sprue
D. Amoebic colitis

112. MCQ
• Transmural involvement & granuloma are
seen in --1.37aaaII (JIPMER 98)
A. Ulcerative coilitis
B. Crohn's disease
C. Tropical sprue
D. Amoebic colitis

113. MCQ
• Yellowish exudates at multiple sites seen in
colonoscopy indicates ----1.38aaaII
(Kerala 03)
A. Crohn's disease
B. Hirshspruing disease
C. Tuberculosiss
D. Lymphoma

114. MCQ
• Yellowish exudates at multiple sites seen in
colonoscopy indicates ----1.38aaaII
(Kerala 03)
A. Crohn's disease
B. Hirshspruing disease
C. Tuberculosiss
D. Lymphoma

115. MCQ
• True regarding crohns disease are A/E ---
15.6 / aiims pgmee questions - june, 1997
A. Scleroderma
B. Transmural infection
C. Cobble stone appearance
D. Skin involvement

116. MCQ
• True regarding crohns disease are A/E ---
15.6 / aiims pgmee questions - june, 1997
A. Scleroderma
B. Transmural infection
C. Cobble stone appearance
D. Skin involvement

117. MCQ
• Which of the following is the established
biological therapy for Crohns disease-
(AIIMSNov 05) --181 arvind arrora 2/e
A. Anti TNF a-antibody
B. IL-1 antagonist
C. IL-6 antagonist
D. IL-8 antagonist

118. MCQ
• Which of the following is the established
biological therapy for Crohns disease-
(AIIMSNov 05) --181 arvind arrora 2/e
A. Anti TNF a-antibody
B. IL-1 antagonist
C. IL-6 antagonist
D. IL-8 antagonist

119. MCQ
• Which one of the following drugs is useful
in treating Crohn's disease ? -–--- 182
arvind arrora 2/e (Karn PG MEE 2006)
A. Infliximab
B. Azathioprine
C. Tacrolimus
D. Cyclosporine

120. MCQ
• Which one of the following drugs is useful
in treating Crohn's disease ? -–--- 182
arvind arrora 2/e (Karn PG MEE 2006)
A. Infliximab
B. Azathioprine
C. Tacrolimus
D. Cyclosporine

121. MCQ
• Ulcers appearing like 'knife cuts vulva are
seen in
A. Bechets disease
B. Psoriasis
C. Crohns disease
D. Tuberculosis

122. MCQ
• Ulcers appearing like 'knife cuts vulva are
seen in
A. Bechets disease
B. Psoriasis
C. Crohns disease
D. Tuberculosis

123. MCQ
• Crohn's disease may be caused by which
one of following infectious agents: (Al 08)
A. Clostridium difficle
B. Mycobacterium paratuberculosis
C. Cytomegalo virus (CMV)
D. Mycoplasma

124. MCQ
• Crohn's disease may be caused by which
one of following infectious agents: (Al 08)
A. Clostridium difficle
B. Mycobacterium paratuberculosis
C. Cytomegalo virus (CMV)
D. Mycoplasma

125. MCQ
• Clubbing of fingers is caused by all except--
-------182pgmee AT AG
A. Acyanotic heart disease (UPSC 87)
B. Ulcerative colitis
C. Crohns disease
D. Billiarv cirrhosis

126. MCQ
• Clubbing of fingers is caused by all except--
-------182pgmee AT AG
A. Acyanotic heart disease (UPSC 87)
B. Ulcerative colitis
C. Crohns disease
D. Billiarv cirrhosis

127. MCQ
• A 25 year old male presents with a history of
chronic diarrhea. Pathological examination
reveals cryptitis and crypt abscesses. The
likely diagnosis is: (Al 08)
A. Crohn's disease
B. Ulcerative colitis
C. Giardiasis
D. Microscipic colitis
E. B>A

128. MCQ
• A 25 year old male presents with a history of
chronic diarrhea. Pathological examination
reveals cryptitis and crypt abscesses. The
likely diagnosis is: (Al 08)
A. Crohn's disease
B. Ulcerative colitis
C. Giardiasis
D. Microscipic colitis
E. B>A

129. MCQ
• Extra intestinal manifestations of crohn
disease -----1.119aaa vol III (PGI June 05)
A. Uveitis
B. Sclerosing cholangitis
C. Osteoarthritis
D. Skin nodules

130. MCQ
• Extra intestinal manifestations of crohn
disease -----1.119aaa vol III (PGI June 05)
A. Uveitis
B. Sclerosing cholangitis
C. Osteoarthritis
D. Skin nodules

131. MCQ
• A 35 years old woman complaints of attacks
of breathlessness cyanosis and flushing.
Apart from occasional diarrhoea, she has no
abdominal symptoms. Abdominal
examinations reveals an enlarged nodular
liver. If leparotomy is done, one would
expect to find - (UPSC 88) ----1122aaa vol
III
A. An ovarian tumour
B. A multicentric hepatoma
C. An appendicular carcinoid
D. d) Crohn's disease

132. MCQ
• A 35 years old woman complaints of attacks
of breathlessness cyanosis and flushing.
Apart from occasional diarrhoea, she has no
abdominal symptoms. Abdominal
examinations reveals an enlarged nodular
liver. If leparotomy is done, one would
expect to find - (UPSC 88) ----1122aaa vol
III
A. An ovarian tumour
B. A multicentric hepatoma
C. An appendicular carcinoid
D. d) Crohn's disease

133. MCQ
• Crohn's disease (Regional enteritis)It is a disease of Ileum
but can affect any part of gastrointestinal tract, ileocolonic
being the most common.10% of patients have a first degree
relative with the disease and an association with
ankylosing spondylitis.
• Patholotgical features are -
A. Fibrotic thickenign of the intestinal wall with a narrow lumen.
B. Dilated gut just proximal to the stricture
C. Oedemotuos mucosa with a cobble stone appearance
D. Mesenteric thickening with enlarged mesentric lymph nodes.
E. Skip lesions and noncaseating giant cell granulomas.

134. MCQ
• Crohn's disease (Regional enteritis)It is a disease of Ileum
but can affect any part of gastrointestinal tract, ileocolonic
being the most common.10% of patients have a first degree
relative with the disease and an association with
ankylosing spondylitis.
• Patholotgical features are -
A. Fibrotic thickenign of the intestinal wall with a narrow lumen.
B. Dilated gut just proximal to the stricture
C. Oedemotuos mucosa with a cobble stone appearance
D. Mesenteric thickening with enlarged mesentric lymph nodes.
E. Skip lesions and noncaseating giant cell granulomas.

135. Teaching Point
• Presentation may be acute pain with diarrhoea or chronic.
In chronic cases there may be transmural fissuring; infra-
abdominal abscesses and fistulas (enteroenteric or
enterocutaneous)
Small bowel enema shows a narrow terminal ileum with
string sign of Kantor,_
,"Treatment of Crohn's Disease
• Steroids are the mainstay of treatment
but surgery is indicated when there is
• Recurrent intestinal obstruction
• Bleeding
Perforation Perianal disease Fulminant colitis Intestinal
fistula