Prevalence of Vitamin D Deficiency is Similarly High in Young Patients with Crohn\'s Disease and Ulcerative ColitisRead less
![Prevalence of Vitamin D Deficiency is Similarly High in Young Patients with Crohn’s Disease and Ulcerative Colitis Helen Pappa, MD, MPH, Catherine Gordon, MD, MS, Tracee Cook, MSN, PNP, Daniel Clinton, SN, Brian Horr, BA, Richard Grand, MD Inflammatory Bowel Disease Center and Division of Gastroenterology and Nutrition, Children’s Hospital Boston and Harvard Medical School ,[object Object],[object Object],Background Aims ,[object Object],[object Object],[object Object],Methods and Definitions ,[object Object],[object Object],[object Object],[object Object],[object Object],The Prevalence of Vitamin D Deficiency is Higher in Patients with CD and UC, in Comparison to Healthy MA Youth Vitamin D Levels and Disease Characteristics in Our IBD Patients Vitamin D Levels Correlate Positively with Disease Duration in All Patients with IBD N = 134 Vitamin D Levels are Lower in Newly Diagnosed IBD Patients vs. Patients with Long-Standing Disease Summary Vitamin D Levels are Higher Among UC Patients with Longer Disease Duration or Higher Steroid Exposure Conclusions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],* Pearson x 2 = 0.531 + Pearson x 2 = 0.556 * p = 0.815 (Mann-Whitney) † p = 0.856 ‡ p = 0.229 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],A. B. 4.6% 2(25%) 5(14.7%) + 18(19.6%)+ 24(18.7%) 25OHD < 8 24.1% 2(25%) 11(32.4%)* 35(38%)* 47 (35.8%) 25OHD < 15 Healthy MA Youth IC N = 8 UC N = 32 CD N = 92 ALL IBD N = 134 6,428 ‡ (± 8,440) 3,764 ‡ (± 3,715) 4,460 (± 5,658) Lifetime steroids (mg) 36 † (± 42) 32.9 † (± 32.9) 33.5 (± 34.9) Disease duration (mo) 18.4 * (± 8.5) 19.8 * (± 12.9) 19.6 (± 12) 25OHD UC N=34 CD N=92 ALL N=134 Mean value ± SD 0.421 -0.074 Lifetime steroids 0.003 0.253 Disease duration P-value Spearman rho 0.014 0.198 0.016 0.070 P-value (Mann-Whitney) 0.438 -0.145 0.412 0.19 Spearman rho UC CD UC CD Lifetime steroids Disease duration 0.05 0.102 0.014 P-value (Mann-Whitney) 20.8 (±9) 21.3 (±14.2) 21.4 (±13.2) OLD Dx 14.7 (±6.2) 17.1 (±9.8) 16.3 (±8.9) NEW Dx UC New:Old = 13:21 CD New:Old = 32:60 ALL IBD New:Old = 48:86 Levels of Serum 25OHD ( + SD)](https://image.slidesharecdn.com/ddw2005finalppt-12976206010628-phpapp02/85/DDW-2005-Final-Powerpoint-Presentation-1-320.jpg)
