This study surveyed home parenteral nutrition (HPN) in approved centers in France from 1993-1995. 524 new adult patients received HPN, with an incidence of 3.75 per 100,000 adults. Indications for AIDS increased from 8% to 18% while other indications remained stable. At six months, the probability of continuing treatment was 19.5% for cancer and AIDS but 52% for other diagnoses, with death rates of 59% and 9% respectively. Short-term treatment for cancer and AIDS patients was due to poor prognosis, while other patients had a good prognosis but dependency on long-term treatment.