2. INTRODUCTION
Cerebellum
Median age of diagnosis is 6 years.
Craniospinal Irradiation (CSI)
laterally opposed cranial fields, are matched to a posterior
spine
3. RATIONALE FOR CRANIOSPINAL
IRRADIATION(CSI) IN MEDULLOBLASTOMA
CSF dissemination is known in 16-46% of cases
Posterior fossa, spinal cord, ventricular walls & supratentorial region
including the cribriform plate form the main sites of relapse.
Being radiosensitive, RT is curative in up to 70% of standard risk
patients.
5. PLANNING
Symmetrical bilateral cranial field and posterior spine field are
planned to cover entire length of Planning Target Volume
(PTV).
Techniques for matching craniospinal fields.
Collimator/couch rotation
Half beam block
Asymmetric jaws
Penumbra generators
Wedge
Tissue compensator
The both fields are matched either by
GAP JUNCTION METHOD or by
ROTATING COUCH AND COLLIMATOR.
Gap junction method can be done when planning manually
7. MATCHING CRANIAL AND SPINAL FIELD
Because radiation beams are
divergent, adjacent fields can overlap
at depth and give rise to regions of
excessive dose or hot spots.
Overlaps can be avoided by
separating the fields, but this in turn
can give rise to areas of reduced
dose or "cold spots.“ if done
incorrectly .
12. POSTERIOR FOSSA BOOST
Borders
Anterior: Posterior clinoid process.
Posterior: Internal occipital protuberance.
Inferior: C2-C3 interspace.
Superior: Midpoint of foramen magnum & vertex
or 1 cm above the tentorium (as seen on MRI).
Field arrangement
Two lateral opposing fields.
26. MEDULLOBLASTOMA
I. Craniospinal Fields Are Given .
II. Both The Fields Are Orthogonal To Each Other .
III. BiLaterals
IV. Posterior
NOTE :
There is a possibility of a large DOSAGE ERROR across the JUNCTION .
Consequently, this region is at risk for TUMOR RECURRENCE if
UNDERDOSED
SEVERE COMPLICATIONS if OVERDOSED
27. PLANNING
Having field size limitation to covert entire PTV (40*40 CM2).
TWO FILEDS ARE GIVEN
BILATERALS FOR CNI (CRANIOSPINAL IRRADIATION )
POSTERIOR FOR SPINE IRRADIATION
FIELDS
CRANIAL
(BILATERAL
S)
CERVICOTHORACIC
SPINE FIELD
LUMBOSACRAL
SYMMETRICAL
SPINE FIELD
SPINAL
(POSTERIO
R)
28. STEP-1
1. Firstly , BILATERALS are given for CNI .
2. Secondly, POSTERIOR SPINE FIELD is given through the couch
,gantry @ 180
3. In the given patient one field is enough to cover the spine
4. the field is given such that the PTV is covered adequately
5. After calculating dose for the same the result will be :
HOTSPOTS will be there and the dose to OARS
COLDSPOTS will be there too .
29. STEP-2
The need of FIELD MATCHING as the hotspots are there due to
overlapping of fields
The divergence matching is required
1. The HALF BEAM BLOCK is done in bilaterals
2. The isocenter is set at the border
3. Spine field is given to cover the entire PTV
4. Then with the help of collimation in bilaterals the divergence is
matched
5. At one collimation divergence will be matched exactly and no risk
of dose inhomogeneity
6. Ideally mandible is an oar and should not come in the field but due
to patient positioning or due to the head size this was not achieved
30. STEP-3 (SPINE IS LARGER)
1. Here , two fields are given to cover the spine
2. The half beam blocking is done of the second field
3. Isocenter ??
4. Keeping both the field at 180 ,divergence matching is not
achievable at any collimator angle
5. Therefore here couch is at 90 and the field is given
6. Here we give the second field with gantry at an some angle to
match the divergence which depends on the patient anatomy
7. Once the junction matching is done the dose is calculated .
8. This is how medulloblastoma patient is treated