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The PARTNER 3 Trial María Thiscal López Lluva
The PARTNER 3 Trial María Thiscal López Lluva
The PARTNER 3 Trial María Thiscal López Lluva
The PARTNER 3 Trial María Thiscal López Lluva
The PARTNER 3 Trial María Thiscal López Lluva
The PARTNER 3 Trial María Thiscal López Lluva
Year 1 to 2
The PARTNER 3 Trial María Thiscal López Lluva
Year 1 to 2
The PARTNER 3 Trial María Thiscal López Lluva
Year 1 to 2
The PARTNER 3 Trial María Thiscal López Lluva
The PARTNER 3 Trial María Thiscal López Lluva
The PARTNER 3 Trial María Thiscal López Lluva
The PARTNER 3 Trial María Thiscal López Lluva
CONCLUSIONS
In a defined population of severe symptomatic AS patients who were at low surgical risk, TAVR (using the SAPIEN 3
valve) compared to surgery at 2 years demonstrated:
1. Reduced primary endpoint events (⇣ 37% in death, stroke or CV rehospitalization), BUT...
- More death and stroke events in TAVR patients from 1 to 2 years; but no significant differences at 2 years
- Reduced CV rehospitalizations favoring TAVR
2. Increased valve thrombosis events in TAVR patients, esp. from 1 to 2 years
3. Hemodynamic improvements and frequency of moderate or mild paravalvular regurgitation were unchanged
between 1 and 2 years both TAVR and surgery patients.

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PARTNER 3 Trial

  • 1. The PARTNER 3 Trial María Thiscal López Lluva
  • 2. The PARTNER 3 Trial María Thiscal López Lluva
  • 3. The PARTNER 3 Trial María Thiscal López Lluva
  • 4. The PARTNER 3 Trial María Thiscal López Lluva
  • 5. The PARTNER 3 Trial María Thiscal López Lluva
  • 6. The PARTNER 3 Trial María Thiscal López Lluva Year 1 to 2
  • 7. The PARTNER 3 Trial María Thiscal López Lluva Year 1 to 2
  • 8. The PARTNER 3 Trial María Thiscal López Lluva Year 1 to 2
  • 9. The PARTNER 3 Trial María Thiscal López Lluva
  • 10. The PARTNER 3 Trial María Thiscal López Lluva
  • 11. The PARTNER 3 Trial María Thiscal López Lluva
  • 12. The PARTNER 3 Trial María Thiscal López Lluva CONCLUSIONS In a defined population of severe symptomatic AS patients who were at low surgical risk, TAVR (using the SAPIEN 3 valve) compared to surgery at 2 years demonstrated: 1. Reduced primary endpoint events (⇣ 37% in death, stroke or CV rehospitalization), BUT... - More death and stroke events in TAVR patients from 1 to 2 years; but no significant differences at 2 years - Reduced CV rehospitalizations favoring TAVR 2. Increased valve thrombosis events in TAVR patients, esp. from 1 to 2 years 3. Hemodynamic improvements and frequency of moderate or mild paravalvular regurgitation were unchanged between 1 and 2 years both TAVR and surgery patients.