You have identified a novel enzyme. Supercoiled DNA shows an upward mobility shift following a short incubation with the enzyme. Following a long incubation with the enzyme, the supercoiled DNA seems to disappear or be converted in a large number of small fragments. What kind of enzyme is our novel enzyme likely to be? Type I topoisomerase Type II topoisomerase Restriction enzyme DNA nuclease A and B are both correct Solution .C. Restriction enzymes . are a class of enzymes that act upon the DNA molecule at specific site and cleave DNA molecule into small fragments..