1. Presenter : Nick Xydis
Teammates: Nkele Davis and Deborah Ohiani-Jegede
Client: Brad Clay, bioMerieux
2.
Biofilms are an aggregate of microorganism where cells
are stuck to each other and/or a surface
Can form contact lens cases due to improper
cleaning/user non-compliance
Contact lens contamination can lead to microbial keratitis,
conjunctivitis, staphylococci which may require surgery
3.
Usability
Within 3” x 5”
Weight: < 5 lb
Operating time: < 1 hours
Visual timer display
Set up Time: < 30
seconds
Sound during application:
< 40 dB
Autonomous system,
turns on and off automatically
Waterproof
Economics
Effectiveness
Cost: < $200 (prescribed by
doctor)
Power Draw: < .25kWhr per
application
95% biofilm destruction
biofilm growth prevention
No damage to lens case and
lens
Durability
meets all other specification
requirements after 5 years
4.
Need aluminum bracket on back of
device to cool LEDs
Convection Heat Transfer
q = h*A*(Tj-Ta)
h : natural air convection coefficient
A : area of metal bracket
Tj : junction temperature
Ta : ambient temperature
Minimum Area = 8.68cm2
7.
P = V*I
P = Vf*If*(1-WPE)
Vf : Forward Voltage of LED
If : Forward Current of LED
WPE: wall plug efficiency
LED cannot exceed forward current or
forward voltage - risk permanently
compromising device
Use LED Driver to monitor LEDs
R = (Vs - Vf)/If Calculate current limiting
resistor
Control Signal
From
Microcontroller
Differential
Voltage Signal
to A/D
18. Part
Manufacturer and Part
Number
Number of
Parts
Power Draw
(W)
2
0.99
UVCAN-255-1
Microcontroller
Voltage Regulator
MSP430FG437 Texas
Instruments
TN0604
Dimensions
$250
Crystal IS, Inc.
LEDs
Cost
*Future Estimate:
0.526in (13.36mm) x 0.488in (12.401mm) x
0.333in(8.45mm)
$25 or less
1
Active: 6.6*10&-4
Standby:
2.42*10^-6
3.85
1000+units
0.1in(5.1mm) x 0.26in(6.6mm) x 0.047in(1.20mm)
1
1.2
$0.22
0.11in(2.9mm) x 0.11(2.8mm) x 0.043(1.1mm)
1
2.5
$5.37
100+units
3.15in(80mm)x1.42in(36mm)x0.43in(11mm)
1
$0.75
$1.72
1000+ units
0.19in(4.90mm) x 0.12in(3.00mm) x
0.043in(1.10mm)
1
0.72
$0.25
100+ units
0.197in(5.0mm)x1.244in(31.6mm)x0.22in (5.6mm)
NJM78L00
LCD Display
A/D Converter
EastRising ERM1602DNR-5
Microchip Technology
MCP3301-CI/P
Indicator LED
Jameco Electronics LTL293SJW AIGaAs Red-Green
19. Part
Manufacturer and Part
Number
Number of
Power Draw (W)
Parts
Cost
Dimensions
Part 1:
Magnetic Interlock
Cherry Electrical AS201801
1
0
$1.76
500+units
12.91in(328.00mm) x 0.433in (11.00mm) x
0.236in(6.00mm)
Part 2:
0.906in(23.00mm) x 0.433in (11.00mm) x
0.236in(6.00mm)
Power Switch
Cherry Electronics AS201801
1
120
$0.6105
1000+units
0.841in(21.36mm) x 0.783in(19.89mm) x
0.976in(24.79mm)
Field Effect
Transistor
Mouser, Inc. TNO604
3
6.4
$0.55
1000+units
0.175in(4.445mm) x 0.67in(17.018mm)x
0.125in (3.175mm)
Resistors
Vishay/BC Components
PR01000103009JR500
6
1
$0.04
1000+units
(2.5mm)x(6.5mm)x(0.58mm)
Watchdog Timer
STMicroelectronics STM690T/S/R
1
1.2*10^-4
$1.23
0.203in(5.16mm) x 0.122in(3.099mm) x
0.037in(0.94mm)
20.
Cost: $35,000 for 30 prototypes
Material: Polycarbonate + Acrylonitrile
butadiene styrene blend (PC/ABS)
commonly used in medical devices
high impact strength, high flow for better
processing, great dimensional stability (mold
shrinkage, thermal expansion, water
absorption)
Lead Time: 3-5 days
21.
Accelerated UV Testing
Mold optimization
Develop a more rigorous protocol for
validating 95% inactivation rate design
requirement
Work with local optometrists to
execute patient surveys
22.
According to National Eye Institute 8.25% of Americans use contact
lenses
Poor vision is hereditary
Average family size = 3.14 people
Use Diffusion of Innovation Curve and choose “Innovators” as
reasonable estimate to determine 15,000 initial production units
23.
Design a specially formulated UVC resistant case for
contact lenses
UVC disinfection of other in-dwelling devices such as
dentures
UVC fiber optics to target biofilm growth on catheters
or endotracheal tubes
Disinfection of recirculating air or water
