Indicate all persons/investigators participating in the Program and explain the role of each participant in the Program. To test the mir-22 function of cancer patients (blood sampling). Note that the type of study is basic research Solution Answer: The participants/investigators participating in a program includes the PI (Principal Investigator), Co-PI (Co-Principal Investigator), faculty participants and human participants. Role of each of them have been discussed below: 1. PI-The primary person to conduct a public service project or sponsored project in accordance with the laws and regulations of the institution concerned. 2. Co-PI- They have responsibilities similar to the PI and has obligations to monitor as to whether the projects are conducted in compliance with the rules and regulations. 3. Faculty participant- They are not directly involved in the research projects, but may act as a key personnel with lesser responsibilities than the PI and Co-PI. 4. Human participant- These are individuals upon whom the investigators conduct research to obtain data either through direct intervention or obtaining individual information about the participant which are not to be made public. Before collecting blood for sampling to study mir-22 function in cancer patients, the human participants should be fully informed (by the investigators) about the facts, benefits, risks and discomforts they might face during the program. These factors are part of the ethical and legal aspects as these might change the participants willingness to participate in the program. The research protocols includes diet, survey, experimental drug intervention and exercise studies. For children (below 18 years), prior consent of the parents are standard requirements. Consents in most cases are to be documented, although it might be waived in special cases..