The 2nd statement and 3rd statement follow the seed and soil theory of metastasis or simply metastasis. It involves the main step “spreading of cells”. Integrins are responsible for signal transduction and do not move. Seed and soil theory is acceptable to the both statements. Micrometastases even remain dormant but have some growth in an organ. This organ is still work as soil for Micrometastases. So tumor cell are still as seed and organ is soil for them. Solution The 2nd statement and 3rd statement follow the seed and soil theory of metastasis or simply metastasis. It involves the main step “spreading of cells”. Integrins are responsible for signal transduction and do not move. Seed and soil theory is acceptable to the both statements. Micrometastases even remain dormant but have some growth in an organ. This organ is still work as soil for Micrometastases. So tumor cell are still as seed and organ is soil for them..

1. The 2nd statement and 3rd statement follow the seed and soil theory of metastasis or simply
metastasis. It involves the main step “spreading of cells”. Integrins are responsible for signal
transduction and do not move. Seed and soil theory is acceptable to the both statements.
Micrometastases even remain dormant but have some growth in an organ. This organ is still
work as soil for Micrometastases. So tumor cell are still as seed and organ is soil for them.
Solution
The 2nd statement and 3rd statement follow the seed and soil theory of metastasis or simply
metastasis. It involves the main step “spreading of cells”. Integrins are responsible for signal
transduction and do not move. Seed and soil theory is acceptable to the both statements.
Micrometastases even remain dormant but have some growth in an organ. This organ is still
work as soil for Micrometastases. So tumor cell are still as seed and organ is soil for them.