In Nepal, the earthquake affected 14 districts comprising a population of about 5.3 million in the early year of 2015. According to government of Nepal (GoN) figures, 488,579 houses were destroyed and 260,026 damaged. The water resources of about 660,000 to 1.3 million people were affected and between 850,000 to 1.7 million need sanitation support. Out of 5.3 million people in these 14 affected districts, 2.7 million were displaced and are likely to be at an increased risk for infectious diseases including cholera. These displaced communities are the most vulnerable population and should have the highest priority for implementation of preventive strategies, including possible mass vaccinations. The Department of Health Services (DoHS), Government of Nepal (GON) implemented preventive strategy against enteric diseases including WASH in conjunction oral cholera vaccination in selected high risk villages of the affected districts.