Yes,all macromolecule are passed from nuclear pore envelope to cytoplasmic compartments(including ER).Transport of macromolecules between the nuclear and cytoplasmic compartments occurs through nuclear pore complexes that span the double membrane of this envelope. Solution Yes,all macromolecule are passed from nuclear pore envelope to cytoplasmic compartments(including ER).Transport of macromolecules between the nuclear and cytoplasmic compartments occurs through nuclear pore complexes that span the double membrane of this envelope..