PPT includes all questions of Industrial pharmacy I

1. Industrial Pharmacy – I
(BP502T)
Questioners
By Ankita Burande
Assistant Professor
Nagpur College of Pharmacy Nagpur

2. Unit1: Preformulation Studies
Questions : (10 x 2 = 20 Marks)
 What is Racemization? Give example.
 Write the methods to study of solid forms of a substance
 What is the need of preformulation studies in pharmaceutical product
development?
 Write the differences between crystalline and amorphous forms of solid.
 Define preformulation studies.
 Write the BCS classification of drugs.
 What is preformulation study
 Define bulk density and write its importance in Pharmacy

3. Unit1: Preformulation Studies
Questions : (2 x 10 = 20 Marks)
 (a) Discuss about crystallinity of solid substances. (b) Describe the
chemical reactions involved in degradation of API
 Explain the study of physical characteristics during preformulation
Questions : (7 x 5 = 35 Marks)
 How flow properties of powders are measured?
 Explain polymorphism.
 Write a note on polymorphism and its applications.
 What is BCS classification? Discuss its importance.

4. Unit 2: Tablets
Questions : (10 x 2 = 20 Marks)
 Explain friability test for tablets.
 Explain the importance of enteric coating of tablet.
 Describe the granulation methods for tablet manufacturing.
 Classify tablets and give ideal characteristics of tablets.
 What are the unofficial tests for evaluation of tablets.
 Define Enteric coating and give its advantages.
 Define buccal and sublingual tablets.
 Enlist various types of coating materials of tablets.
 Why coating tablets are required
 Classify tablets.
 What is Orange peel effect in tablet coating

5. Unit 2: Tablets
Questions : (2 x 10 = 20 Marks)
 a) Describe the compression cycle for tablet manufacturing. (b) Explain in
process quality control tests for tablet compression.
 (a) Explain perforated coating pans. (b) Write a brief note on filing of
capsules.
 Enlist the excipients used in tablet manufacture with examples. Write their
role and mechanism of action.
 Explain quality control tests of tablets.
 (a) Explain about disintegration and dissolution test for tablets. (b) Write in
detail about evaluation of containers

6. Unit 2: Tablets
Questions : (7 x 5 = 35 Marks)
 Discuss the steps involved in sugar coating of tablets
 Discuss the tablet additives with examples of each class.
 Explain about hardness and friability testing of tablets.
 Write a brief note on manufacturing defects in tablet coating.
 Explain weight variation test and content uniformity test for capsules
 Explain sugar coating of tablets.
 Explain defects in tablet coating

7. Unit 2: Liquid Orals
Questions : (10 x 2 = 20 Marks)
 What are the tests used for detecting type of emulsion
 Give formulation of suspension
 Define emulsion & suspension
Questions : (7 x 5 = 35 Marks)
 Describe the evaluation of liquid orals as per pharmacopoeia
 Write the differences between flocculated and deflocculated
suspensions.
 Discuss the method for preparation of emulsion.
 Explain formulation considerations of liquid dosage forms.
 Write a brief note on filling and packaging of oral liquids.

8. Unit 3: Capsules
Questions : (10 x 2 = 20 Marks)
 Write the differences between type A and type B gelatin
 Outline the steps of manufacturing of hard gelatin capsule SHELL
 Write a note on sizes of hard gelatin capsules
 Mention different sealing methods for hard gelatin capsules
 Define Base adsorption
Questions : (2 x 10 = 20 Marks)
 Explain in detail about manufacturing of hard gelatin capsules and soft gelatin capsules.
 (a) Explain perforated coating pans. (b) Write a brief note on filing of capsules.
 Explain the formulation and quantity control tests for hard gelatin or soft gelatin
capsules
 (a) Write in brief about the manufacture of Aerosols. (b) Explain about the defects in
capsules.

9. Unit 3: Capsules
Questions : (7 x 5 = 35 Marks)
 Describe the manufacturing defects of hard gelatin capsules
 Explain weight variation test and content uniformity test for capsules.
 Explain method of preparation of hard gelatin capsule shell.
 Describe the manufacturing of soft gelatin capsules.

10. Unit 3: Pellets
Questions : (10 x 2 = 20 Marks)
 Write the advantages of pellets.
 Enlist the pelletization techniques
 What are pellets? Give advantages of pellets
Questions : (7 x 5 = 35 Marks)
 Explain in detail about extrusion-spheronization technique
 Enlist techniques of pelletization. Explain advantages of pallets over
conventional dosage forms.
 Write a note on palletization process.
 Write in detail about solution layering.
 Explain powder and liquid layering methods for pelletization, with a note
on equipment used for the same.

11. Unit 4: Parenteral products
Questions : (10 x 2 = 20 Marks)
 Explain the concept of aseptic processing
 Plastic bottles are preferred over glass bottles for saline. Justify.
 Write the type of glass with their uses for pharmaceutical products
 What is isotonicity? Explain its importance for parenteral products.
 Write the principle involved in LAL test for injectables
 What are Tonicity modifiers
 Write the significance of isotonicity in parenterals
 What are the vehicles used in the preparation of parenterals?
 Classify parenteral with suitable examples.
 What are pyrogens?
 What is aseptic area?
 What are the vehicles used in the preparation of parenterals.
 Classify parenteral with suitable example

12. Unit 4: Parenteral products
Questions : (2 x 10 = 20 Marks)
 (a) Describe sterility test procedures as per official books. (b) Discuss formulation considerations for
ophthalmic products.
 (a) Explain pyrogen test for parenterals. (b) Discuss about the formulation of pharmaceutical aerosols.
 Write a note on production facilities required for parenteral preparations.
 Give the layout for manufacture of parenteral formulations
 Explain formulation and the production of parenterals.
Questions : (7 x 5 = 35 Marks)
 Elaborate the parenteral additives with their examples.
 What are pyrogens? Discuss the pyrogen test for injectables.
 Elaborate water attack test USP and powder glass test USP for packaging glass.
 Discuss quality control of parenteral products.
 Write a note on LAL test & sterility test.
 Explain the process of freeze drying.
 Write a note on injectable suspensions

13. Unit 4: Ophthalmic Products
Questions : (10 x 2 = 20 Marks)
 What are the special instructions to be printed on the eye drop container
according to drugs and cosmetics act.
Questions. (2 x 10 = 20 Marks)
 (a) Describe sterility test procedures as per official books. (b) Discuss
formulation considerations for ophthalmic products.
Questions. (7 x 5 = 35 Marks)
 Explain Draize eye test for opthalmics.
 Explain sterility test for ophthalmic products.
 Write a note on formulation & lebelling of eye drops
 Explain quality control tests of eye ointment
 ite a note on formulation & lebelling of eye drops

14. Unit 5: Cosmetics:
Questions. (10 x 2 = 20 Marks)
 Define cosmetics and give classification of cosmetics with examples
 List out various ingredients used in tooth paste.
 List out various ingredients used in tooth paste
 What is the difference between cold cream & Vanishing cream.
 How sunscreen products help to protect skin against UV radiation?
Questions. (2 x 10 = 20 Marks)
 a) Elucidate the manufacturing of lipstick. (b) What are the possible interactions
between content and packaging material.
Questions. (7 x 5 = 35 Marks)
 Discuss the manufacturing, and uses of cold cream and vanishing cream
 Describe ingredients for toothpaste manufacturing
 Write the formulation of cold cream.
 Write a note on formulation of hair dyes.

15. Unit 5: Pharmaceutical Aerosols:
Questions. (10 x 2 = 20 Marks)
 Illustrate the components of aerosol system with the help of neat diagram.
 Define Propellant.
 What are different types of aerosols?
Questions. (2 x 10 = 20 Marks)
 (a) Describe the components of aerosol system with the help of a neat diagram. (b)
Discuss the types of aerosol system.
 a) Explain pyrogen test for parenterals. (b) Discuss about the formulation of
pharmaceutical aerosols.
 (a) Write in brief about the manufacture of Aerosols. (b) Explain about the defects
in capsules.
 Explain the formulation and evaluation of aerosols.
Questions. (7 x 5 = 35 Marks)
 Write a brief note on propellants in Aerosols

16. Unit 5: Packaging Material Science
Questions. (10 x 2 = 20 Marks)
 Write the type of glass with their uses for pharmaceutical products
 What are the different materials used for packaging?
Questions. (2 x 10 = 20 Marks)
 a) Elucidate the manufacturing of lipstick. (b) What are the possible interactions
between content and packaging material
Questions. (7 x 5 = 35 Marks)
 Explain the criteria for selection of packaging materials.
 Explain the factors affecting selection of pharmaceutical packaging materials.
 Write a note on factors influencing choice of containers