MaranyanneMoupanaga{Pharmacist}
We learn more by looking for the answer to a question and not finding it than we do from
l...
MaranyanneMoupanaga{Pharmacist}
Effervescent tablets
Dispensing tablets
Hypodermic tablets
Tablet triturates
QUESTION TWO{...
MaranyanneMoupanaga{Pharmacist}
QUESTION 6
Liquid oral dosage form vs tablet,what are the shortcomings and limitations on ...
MaranyanneMoupanaga{Pharmacist}
What is the value, to the pharmaceutical dosage form designer, of studying multiple solid
...
Upcoming SlideShare
Loading in …5
×

Tablets

336 views

Published on

pharmaceutics test,answer them

Published in: Education
0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total views
336
On SlideShare
0
From Embeds
0
Number of Embeds
3
Actions
Shares
0
Downloads
3
Comments
0
Likes
0
Embeds 0
No embeds

No notes for slide

Tablets

  1. 1. MaranyanneMoupanaga{Pharmacist} We learn more by looking for the answer to a question and not finding it than we do from learning the answer itself.”Lloyd Alexander As a Pharmaceutics Dosage Form Designer, study the manufacturing formula and answer the following questions in details: QUESTION ONE (110) MARKS There are different types and Classes of Tablets that have been identified.in each type and class, Please give five{5} examples of used drugs in each class(100)marks Clearly describe the manufacturing process of uncoated tablets. (10) 1.ORAL TABLETS FOR INGESTION Compressed tablets or standard compressed tablets Multiple compressed tablets -Layered tablets -Compression coated tablets Repeat-action tablets Delayed-action and enteric 5.coated tablets Sugar and chocolate coated tables Film-coated tablets Chewable tablets 2. TABLETS USED IN ORAL CAVITIES Buccal tablets Sublingual tablets Troches and lozenges Dental cones 3. TABLETS ADMINISTERED BY OTHER ROUTES Implantation tablets Vaginal tablets Rectal tablets 4. TABLETS USED TO PREPARE SOLUTIONS
  2. 2. MaranyanneMoupanaga{Pharmacist} Effervescent tablets Dispensing tablets Hypodermic tablets Tablet triturates QUESTION TWO{70} Explain the following terms used in tablet characterisation and, for each, indicate briefly its effect in drug bioavailability. {10} each uniformity of weight Assay Limit of foreign substances Dissolution Hardness Disintegration friability QUESTION 2 Define “Solubility”. (4) Among factors that affect Solubility, Temperature is a significant factor. Describe in full how it affects solubility, giving examples where possible. (15) How does particle size affect Solubility? (6) QUESTION 3 What factors affect powder flowability? For the given factors, how can they be adjusted in order to improve flowability? (4,4) QUESTION 5 What are the advantages and disadvantages of using a tablet over a capsule.{15}
  3. 3. MaranyanneMoupanaga{Pharmacist} QUESTION 6 Liquid oral dosage form vs tablet,what are the shortcomings and limitations on liquid dosage form over tablets?(10) QUESTION 7 20 Marks Explain the following terms used in powder characterization and, for each, indicate briefly its effect in drug bioavailability. (a) Particle size (6) (b) Surface area (3) (c) Crystal form (4) (d) Polymorphism (7) QUESTION 8 20 Marks In tablet manufacture, what is “granulation”? (5) Describe the granulation properties that affect tablet quality. (15) QUESTION 10 20 Marks A National Drug Regulatory Authority has to decide between a 2-colour capsule, a plain capsule and a sugar coated tablet as the dosage form of an essential medicine. Advise on what factors the Authority needs to take into account in their decision making process. QUESTION 11{15}
  4. 4. MaranyanneMoupanaga{Pharmacist} What is the value, to the pharmaceutical dosage form designer, of studying multiple solid forms? Describe in full the use of Gelatin Capsules in pharmaceutical industry. Explain the process of manufacture of Gelatin Capsules. QUESTION 12{5} What are the challenges of ‘multiple solid forms’ in dosage design? QUESTION 13{20} In tablet manufacture, granulation is a process that increases particle size; milling is a process that reduces particle size. So, why granulate tablet powders, and then mill the resultant granules? Use named examples. (14) Show not more than 3 challenges encountered in tablet compression. (6) QUESTION 14 {20} What tablet characteristics does Particle Size and Shape of granules affect? (6) Bulk density of the granulation affects tablet quality. Describe how . (6) Describe in detail one method of measuring bulk density of a powder. (8) QUESTION 15 What 3 established methods are there in granule manufacture? (3) Describe the advantages and disadvantages of direct compression in tablet manufacture. QUESTION 16 11. Describe the manufacture of soft gelatin capsules. (20) …….AND GOOD LUCK!!!!!

×