1. Jules Bordet
(13 Jun 1870 - 6 Apr 1961)
Belgian bacteriologist and immunologist
“ Science defeats Darkness”
Prepared by :
Jyotirmayee Sahoo
Aakash Verma
Aditya Amrut Pawar 1
2. Early Life and Education
• Jules Bordet was born at Soignies , Belgium in
1870
• He graduated as Doctor of Medicine from
the Free University of Brussels in 1892
• He got Noble Prize in Physiology or Medicine in
1919 for his discoveries relating to immunity
• He was affiliated to Brussels University, Brussels,
Belgium at the time when he got Noble Prize
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3. Noble Prize Work
• Our immune system protects us from attacks by
microorganisms and poisonous substances
• The blood includes factors or bodies that destroy bacteria
• By doing studies of cholera in 1896, Jules Bordet came into
conclusion that there are two types of factors in the blood:
1.Antibodies formed by immunization against specific
bacteria
2.Complement proteins that also exist in blood that is not
immunized.
• Antibodies and complement proteins are bound to one another,
which can be used to detect certain diseases, including syphilis
• By following the principles of Bordet work, the same principle
is used today in serologic testing of countless diseases
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4. References
• Jules Bordet – Facts. NobelPrize.org. Nobel Media AB 2018.
Sun. 19 Aug 2018.
https://www.nobelprize.org/prizes/medicine/1919/bordet/facts/>
• Schmalstieg Jr, Frank C., and Armond S. Goldman. "Jules Bordet
(1870–1961): a bridge between early and modern
immunology." Journal of medical biography 17.4 (2009): 217-
224.
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Editor's Notes
The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's cell membrane. It is part of the innate immune system