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MS
Urologische Aspecten
R. Laduc, uroloog ZRT
Op de lange duur…
• Krijgt een ruime meerderheid van MS
patiënten plasproblemen.
• 60-85%
• In het begin kan zich dit herstellen.
• Bij uitzondering het eerste symptoom.
(1-2%- de Ridder)
Hoe werkt de urine blaas?
• Opslag van urine (vullen)
– Drang tot plassen
– ‘s nachts plassen
• Lozen van urine (legen)
– Traag plassen
– Onvolledig uitplassen
• Mij MS is de blaas gezond, maar hapert de
besturing: samenwerken van de blaasspier met
de sluitspier en de bekkenbodemspieren is
verstoord
Besturing van de blaas
• Pontien mictiecentrum (Big Boss)
• Sacraal mictiecentrum (Manager)
Besturing
Doel van de behandeling
• Klachten bestrijden
– Infecties !
– Incontinentie
– Klachten OA Blaas
• Nierfunctie behouden
Richtlijn neurogene
blaasfunctiestoornissen
• 2012
• Urologen
• Neurologen
• Revalidatieartsen
• Specialisten ouderengeneeskunde
Uitvragen en Onderzoek
• Urine, ontlasting, sexualiteit, neurologie
• Infectie
• Mictiedagboek
• Urodynamisch onderzoek (eerst plasstraal en
achtergebleven urine meten)
Medicamenten 1
• Blaas groot en slap:
– Oxybutinine (Dridase)
– Tolterodine (Detrusitol)
– Solifenacine (Vesicare)
– Fesoterodine (Toviaz)
– Mirabegron (Betmiga)
• Blaas goed leeg:
– Alfuzosine (Xatral)
– Tamsulosine (Omnic)
– Silodosine (Silodyx)
Medicamenten 2
• Combinatie
– Vesomni
• Overig
– Antibiotica (onderhoudsdosis)
– Duodart (bij vergrote prostaat)
– Diazepam (Valium) – spierverslapper
– Baclofen (Lioresal)
– Viagra, Levitra, Cialis, Androskat
Minimaal invasief 1
• Catheterisaties
– C.I.S.C. (handfunctie)
– Speciale catheters
– Overvulling van de blaas voorkomen
– Blaascatheter
– Suprapubische catheter
– Condoomcatheter
Minimaal invasief 2
• Botulisme toxine
– Botox of Dysport
• Dagopname
• Na 9 tot 15 maanden herhalen
• Risico: achterblijven urine
• Spermawinning
• Bekkenbodem fysiotherapie ?
• Incontinentie materiaal
Operatief
• Pacemaker
• Darm op de blaas zetten (lage druk)
• Kunstsluitspier
• Stoma
• Incontinentie bandje
Controles
• Bij hoge blaasdruk elk (e 2) jaar
PTNS?
Multiple Sclerose en blaasproblemen

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Multiple Sclerose en blaasproblemen

  • 2. Op de lange duur… • Krijgt een ruime meerderheid van MS patiënten plasproblemen. • 60-85% • In het begin kan zich dit herstellen. • Bij uitzondering het eerste symptoom. (1-2%- de Ridder)
  • 3. Hoe werkt de urine blaas? • Opslag van urine (vullen) – Drang tot plassen – ‘s nachts plassen • Lozen van urine (legen) – Traag plassen – Onvolledig uitplassen • Mij MS is de blaas gezond, maar hapert de besturing: samenwerken van de blaasspier met de sluitspier en de bekkenbodemspieren is verstoord
  • 4. Besturing van de blaas • Pontien mictiecentrum (Big Boss) • Sacraal mictiecentrum (Manager)
  • 6. Doel van de behandeling • Klachten bestrijden – Infecties ! – Incontinentie – Klachten OA Blaas • Nierfunctie behouden
  • 7. Richtlijn neurogene blaasfunctiestoornissen • 2012 • Urologen • Neurologen • Revalidatieartsen • Specialisten ouderengeneeskunde
  • 8. Uitvragen en Onderzoek • Urine, ontlasting, sexualiteit, neurologie • Infectie • Mictiedagboek • Urodynamisch onderzoek (eerst plasstraal en achtergebleven urine meten)
  • 9. Medicamenten 1 • Blaas groot en slap: – Oxybutinine (Dridase) – Tolterodine (Detrusitol) – Solifenacine (Vesicare) – Fesoterodine (Toviaz) – Mirabegron (Betmiga) • Blaas goed leeg: – Alfuzosine (Xatral) – Tamsulosine (Omnic) – Silodosine (Silodyx)
  • 10. Medicamenten 2 • Combinatie – Vesomni • Overig – Antibiotica (onderhoudsdosis) – Duodart (bij vergrote prostaat) – Diazepam (Valium) – spierverslapper – Baclofen (Lioresal) – Viagra, Levitra, Cialis, Androskat
  • 11. Minimaal invasief 1 • Catheterisaties – C.I.S.C. (handfunctie) – Speciale catheters – Overvulling van de blaas voorkomen – Blaascatheter – Suprapubische catheter – Condoomcatheter
  • 12. Minimaal invasief 2 • Botulisme toxine – Botox of Dysport • Dagopname • Na 9 tot 15 maanden herhalen • Risico: achterblijven urine • Spermawinning • Bekkenbodem fysiotherapie ? • Incontinentie materiaal
  • 13. Operatief • Pacemaker • Darm op de blaas zetten (lage druk) • Kunstsluitspier • Stoma • Incontinentie bandje
  • 14. Controles • Bij hoge blaasdruk elk (e 2) jaar
  • 15. PTNS?