Route Of Drug Administration

1. Route Of Drug Administration
Clinical Pharmacology

2. 1 Entered Route Of Drug Administration
 It Means To Drug Give By GIT
A} Oral Route Of Drug Administration
B} Sub Lingual Route Of Drug Administration
C} Rectal Route Of Drug Administration

3. A} Oral Route Of Drug Administration
 It Means Drug Give By Mouth
Advantage
• It is in easy method of drug administration
• it is does not need antiseptic procedure
• It is not risky Method
• It is cheap route of drug administration
• It is not painful method

4. Disadvantage
 This route is not suitable in emergency cases
 cannot be used in people who are vomiting
 Cannot be used for unconscious person
 Some drug aur harmful for stomach e.g aspirin

5. B} Sub Lingual Route Of Drug Administration
 Drug Is Kept Under Tongue.
Advantage
• Rapidly soluble method
• Easy method
• Cheap method

6.  Most drugs are not available as sublingual
formulations.
 The taste of the sublingual dosage form may
not be liked by the patient.
 Placing the sublingual dosage form under the
tongue until it dissolves may be considered
inconvenient by some patients.
 Irritation to the oral mucosa.
Disadvantage

7. C} Rectal Route Of Drug Administration
 Drug Is Kept In Rectum
Advantage
• It is an easy method
• Drug maybe used in local problem e.g
constipation

8.  Mucosal irritation.
 Patient compliance.
 Erratic and undesired absorption.
 Placement too high into rectum may lead to first
pass metabolism.
 Installation may trigger defecation reaction.
 GI state affects absorption:
Disadvantage

9. 2 Parenteral Route Of Drug
Administration
 It Means To Drug Give By Injection
Advantage
• Can be used for drugs that are poorly
absorbed, inactive or ineffective if given orally.
• The IV route provides immediate onset of
action.
• The intramuscular and subcutaneous routes
can be used to achieve slow or delayed onset
of action.
• Patient concordance problems can be avoided.

10.  Drug administration by these routes is
irreversible and poses more risks than the other
routes.
 It is an invasive route of drug administration
and thus, it can cause fear, pain, tissue damage,
and/or infections.
Disadvantage

11.  It Means To Drug Give By Through Lungs
3 Inhalation Route Of Drug
Administration
Advantage
• It is possible to administer larger doses than this.
• Modifying the dose of the drug, according to the
needs of the patient is simple.
• Inhalation therapy facilitates self-administration
and therefore increases the compliance of patients.
• It is possible to formulate a combination of
different types of drugs in a single dose for the
treatment of disease.

12.  The major disadvantage of the inhalation route
of drug administration is that limited drugs are
suitable for formulation with this technique.
 Cleaning after each application is necessary to
avoid potential contamination.
 The active pharmaceutical ingredients (API) and
excipients those have an unpleasant taste and
odor are difficult to formulate.
Disadvantage

13. 4 Topical Route Of Drug Administration
 It Means To Apply Drugs On Target Part
Advantage
• Fewer Risks of Gastrointestinal Difficulties.
Different individuals absorb medication at
different rates. ...
• Fewer Risks of Abuse. ...
• Easy to Administer. ...
• Reduced Hospital Congestion

14.  Potential production of irritant and
allergic contact dermatitis.
 Decreased penetration in the affected
area.
 Potential rapid appearance of bacterial
resistance.
 Potential alteration of cutaneous flora.
Disadvantage