This conference, entitled “Genome Editing: The Next Frontier”, will be held in Singapore, February 4-7, 2018, and is jointly organized by Fondation IPSEN, AAAS/Science and AAAS/Science Translational Medicine, and the Institute of Molecular and Cell Biology A*STAR Singapore. The meeting will cover a broad range of topics including natural bacterial immune mechanisms, the next generation of genome editing tools, applications of genome editing tools in scientific discovery, and therapeutic applications of genome editing.