2. EPIDEMOLOGY
Diabetic foot ulcers were found in 4.54% newly diagnosed
patients(Sinharay K et. al, 2012)
Prevalence of DFU is about 14.3% in Indian population (according to
a study done in Northern India, Shahi SK et. al)
4. Large sensory fibres – protective sensation is lost
Small fibres can lead to increased pain sensation, allodynia.
Sensory disturbances show a length related pattern with
stocking & glove distribution due to dying back distal
axonopathy
Motor neuropathy can cause claw toes from intrinsic muscle
weakness & equinus contracture of Achilles tendon→ stress on
fore-foot→high focal pressure & skin breakdown.
Sweat gland dysfunction allows the skin to dry & crack→microbe
entry
6. PVD
ABI is unreliable in diabetics as
calcification can lead to high results
masking the severity of disease.
Toe pressure or TcpO2 better indicator.
Angiography is gold standard, but
requires IV contrast infusion.
ABI >0.45 & TcpO2 >40mm Hg
necessary for ulcer to heal.
13. TCC is the gold standard for off-loading of plantar
ulcerations.
ii. Patients with grade 3 or greater ulcers should
undergo incision and drainage and antibiotic therapy,
with wound improvement before TCC application.
iii. Casts should be changed every 2 to 4 weeks until
erythema and edema have resolved and the
temperature of the affected limb has decreased and
become similar to that of the contralateral limb. Ulcers
should be evaluated and debridement should be
performed at the time of cast changes.
iv. Radiographs should be repeated every 4 to 6 weeks,
or more often if there is an acute change.
v. TCC commonly continues for up to 4 months; when
the active disease phase is complete, the patient can be
fitted with a Charcot restraint orthotic walker, later
followed by a custom shoe with orthoses.
14.
15. OPERATIVE TREATMENT –
URGENT SURGICAL INDICATION – NECROTISING FASCITTIS/
GANGRENE/ DEEP ABSCESS
LESS URGENT INDICATIONS ARE - COMPROMISED SOFT TISSUE
ENVELOPE
NEED TO AVOID PROLNGED ANTIBOTICS
LOSS OF MECHANICAL FUNCTION
BONE INVOLVEMENT THAT IS LIMB THREATENING
Known risk factors for diabetic foot complications as
outlined by The American Foot and Ankle Society include
peripheral neuropathy as tested with the 5.07 Semmes-
Weinstein monofilament, signs and symptoms of vascular
insufficiency including absent pulses, trophic skin changes
and/or a history of claudication, partial or total foot amputation,
previous ulcer, previous hospital admission for a diabetic
foot infection, bony deformity, peripheral edema, and
abnormal skin temperatures.