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Prof. U. Murali.
Chronic Wounds
Learning Objectives
•Introduction
•Leg ulcers / Pressure ulcers
• Scars - Hypertrophic scar / Keloid
• Contractures
• Sinus & Fistula
• Chronic wounds fail to progress through the
normal stages of wound healing in a timely
manner.
• They are often characterized by a prolonged
inflammatory phase and persistent
infections.
• The management of chronic wounds
therefore often involves debridement,
control of infection and inflammation and
appropriately selected dressings to correct
moisture imbalances.
• Chronic wounds can be categorized into –
• Vascular ulcers (venous or arterial)
• Diabetic ulcers &
• Pressure ulcers.
Introduction
Leg Ulcers
Prof. U.Murali.
• In developed countries, the most
common chronic wounds are leg
ulcers.
• Defn: An ulcer is a break in the
continuity of the covering
epithelium, either skin or mucous
membrane due to molecular
death.
• A prolonged inflammatory phase
leads to overgrowth of granulation
tissue and attempts to heal by
scarring leave a fibrotic margin.
Leg Ulcers
6
Leg Ulcers
•CBP / Sr. Protein
•Study of discharge – C/S
• Edge biopsy
• X-ray of the part
• FNAC – Lymph node
• Chest X-ray / Mantoux
test
• Arterial / Venous Doppler
Leg Ulcers – Investigations
Leg Ulcers – Treatment
• Cause should be found & treated.
• Correction of anaemia,
deficiencies like protein &
vitamins.
• Control of pain & infection.
• Rest, immobilization, elevation &
avoidance of repeated trauma.
• Care of the ulcer by debridement,
ulcer cleaning & dressing.
• Once the ulcer granulates, defect
is Closed with secondary
suturing, skin graft (or) flaps.
Pressure Ulcers
Prof. U.Murali.
• Pressure sore is tissue necrosis and
ulceration due to prolonged pressure.
It is more prominent between bony
prominence and an external surface.
• They can appear & extend rapidly in
immobile patients and in those with
debilitating illness.
• It can also be called as –
• Trophic ulcer.
• Neuropathic / Neurogenic ulcer.
• Bed sore &
• Decubitus ulcers.
Pressure Sore / Ulcer / Injury
SITES FACTORS
Pressure Sore / Ulcer / Injury
• Pressure
• Sensory
Loss
• Anemia
• Malnutrition
• Moisture
• Def. blood
supply
• Injury
Pressure Sore / Ulcer / Injury
Clinical Features
• Occurs in 5% of in-
patients.
• Deep punched out
edges.
• Non-mobile ulcers
– bone as its base.
Type
Investigations
• Pus – C/S
• Blood tests
• Biopsy
• X-ray - part
Pressure Sore / Ulcer / Injury
• Postural changes:
- Change in position – once in 2 hours
- Lifting limb upwards – 10 s – once in10 mts
• Use of – waterbed/air bed/air-fluidized bed.
• Special pressure dispersion cushion / foams.
• Absorbent porous clothing.
• Regular use of talcum powder – skin dry.
• Urinary & faecal care.
• Good nutrition / Psychological counseling.
• Treating the cause – Anemia/Diabetes….
• Antibiotics & Regular dressings - VAC.
• Slough excision → skin grafting / flap cover
to be done.
P U - Treatment
Scar
Prof. U.Murali.
• A scar is an area of fibrous tissue that
replaces normal skin after an injury. Thus,
scarring is a natural part of the healing
process.
• The remodelling and maturation phase of
wound healing results in scar formation.
• Scars result from the biological process of
wound repair in the skin, as well as in
other organs, and tissues of the body.
• Exception of very minor lesions, every
wound (e.g., after accident, disease, or
surgery) results in some degree of
scarring.
Scar – Introduction
• Initially immature scar is formed during
remodeling phase; this scar is raised, itchy,
hard and pink in colour.
• A mature scar is paler, acellular, softer, flat,
without itching (diminishes).
• An atrophic scar takes the form of a sunken
recess in the skin. These are caused when
underlying structures are lost.
• A hypertrophic scar is excess scar but will not
extend beyond the margin of the scar of the
original wound.
• Keloid is persistent excessive growth of the
scar beyond its margin into the adjacent skin.
Scar – Types
Scar – Prevention
Scar – Treatment
• Hypertrophic scar is excessive
formation of abnormal scar tissue
which is raised, often vascular but
confined within the margin of the
original wound; usually its growth
stops in 6 months and often
regresses spontaneously.
• They are more common in areas of
increased tension, wounds crossing
tension lines, deep dermal burns &
wounds left to heal by secondary
intention (longer than 3 weeks).
Hypertrophic Scar / Keloid
• Keloid scars extend beyond the
boundaries of the original incision (or)
wound, do not spontaneously regress
and are difficult to treat.
• The etiology is unknown but genetic
predisposition is implicated. They often
occur because of relatively minor
trauma and mainly in those with darker
skin pigmentation.
Mgt – Algorithm – Hypertrophic Scar
Mgt – Algorithm – Keloid
Contracture
Prof. U.Murali.
• Contracture is the result of a stiffness or
constriction of muscles, joints, tendons,
ligaments (or) skin that restricts normal
movements.
• Contracture develops when normally
elastic connective tissues become
replaced with inelastic fibrous tissues.
Contracture
• Contractures are either neurally (or) non-
neurally mediated -
• Neurally mediated – are due to spasticity and are a
common sequalae of UMN lesions.
• Non-neurally mediated – contractures are due to
structural adaptations of soft tissues [Occur in
response to prolonged immobilization of soft
tissues].
• Inactivity & Scarring –
from an injury / burn.
• Muscular dystrophy.
• Cerebral palsy.
• Polio.
• Rheumatoid arthritis.
• L E – plantar flexion, hip
flexion & knee flexion
contractures are
common.
• UE – elbow flexion &
supination / adduction &
internal rotation
contractures of shoulder.
• Muscles that cross
multiple joints – biceps,
hamstrings, TFL &
gastrocnemius are
predisposed to
contractures.
Sites Types
Contracture
Causes
• Scar contractures can cause severe
functional, psychological and aesthetic
problems.
• Contractures across joints may restrict the
range of movement, leading to deformity,
impairment and disability.
• Surgical contracture release and
reconstruction can be an effective
treatment option. Release of contracture
surgically and use of skin graft (or) "Z"
plasty (or) different flaps.
• Proper physiotherapy and rehabilitation is
essential.
Contracture
Sinus/Fistula
Prof. U.Murali.
• It is a blind track lined by
granulation tissue leading from an
epithelial surface into the
surrounding tissues.
• Sinus means "hollow" or "a bay"
(Latin).
Sinus / Fistula
• It is an abnormal communication
between the lumen of one viscus to
another or the body surface or between
the vessels.
• Fistula means "flute" or "a pipe or tube."
Sinus / Fistula
Sinus / Fistula
Sinus / Fistula
• Aetiology & treatment of Leg ulcers.
• Basic Investigations & treatment aspects of Leg ulcers.
• Sites & Factors causing Pressure ulcers.
• Staging of Pressure injury | C/F & Treatment of Bedsore.
• Scar – Types, Prevention & Treatment of scars.
• Difference between Hypertrophic scar & Keloid.
• Contracture – Causes, Sites & Types.
• Defn – Sinus / Fistula | Causes for its persistent occurrence.
To Summarize
References
• List 4 aetiological factors causing leg ulcers.
• Mention the staging methods of decubitus ulcer.
• Enumerate 3 sites & 3 factors causing pressure injuries.
• Write the management algorithm for keloid.
• Compare & Contrast hypertrophic scar from keloid.
• Outline the various preventive methods of scar formation.
• Write 5 causes for persistence of a sinus / fistula.
• Mention the various sites & types of contractures.
Question Time
The drug used for intralesional injection of
keloid treatment is –
◼ a) Prednisolone.
◼ b) Triamcinolone.
◼ c) Androgen.
◼ d) Hydrocortisone.
◼
A patient with an injury that has full-thickness loss
without exposure of underlying bone or muscle is
at which of the following pressure ulcer stages? –
◼ a) Stage – 4.
◼ b) Stage – 3.
◼ c) Stage – 2.
◼ d) Stage – 1.
◼
Which one of the following is true regarding leg
ulcers & their location? –
◼ a) Pressure ulcer – Tip of the toes.
◼ b) Arterial insufficiency – Medial side of leg.
◼ c) Venous insufficiency – Gaiter area.
◼ d) Diabetic ulcer – Above medial malleolus.
◼
A hirsute young male has a sinus just above the
natal cleft. Which is the most likely diagnosis? –
◼ a) Tubercular sinus.
◼ b) Hidradenitis suppurativa.
◼ c) Fistula-in-ano.
◼ d) Pilonidal sinus.
◼
Which one of the following sites is more prone
for contracture formation? –
◼ a) Hip flexion.
◼ b) Elbow pronation.
◼ c) External rotation of shoulder.
◼ d) Wrist flexion.
◼
THANK YOU

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Chronic Wounds

  • 2. Learning Objectives •Introduction •Leg ulcers / Pressure ulcers • Scars - Hypertrophic scar / Keloid • Contractures • Sinus & Fistula
  • 3. • Chronic wounds fail to progress through the normal stages of wound healing in a timely manner. • They are often characterized by a prolonged inflammatory phase and persistent infections. • The management of chronic wounds therefore often involves debridement, control of infection and inflammation and appropriately selected dressings to correct moisture imbalances. • Chronic wounds can be categorized into – • Vascular ulcers (venous or arterial) • Diabetic ulcers & • Pressure ulcers. Introduction
  • 5. • In developed countries, the most common chronic wounds are leg ulcers. • Defn: An ulcer is a break in the continuity of the covering epithelium, either skin or mucous membrane due to molecular death. • A prolonged inflammatory phase leads to overgrowth of granulation tissue and attempts to heal by scarring leave a fibrotic margin. Leg Ulcers
  • 7. •CBP / Sr. Protein •Study of discharge – C/S • Edge biopsy • X-ray of the part • FNAC – Lymph node • Chest X-ray / Mantoux test • Arterial / Venous Doppler Leg Ulcers – Investigations
  • 8. Leg Ulcers – Treatment • Cause should be found & treated. • Correction of anaemia, deficiencies like protein & vitamins. • Control of pain & infection. • Rest, immobilization, elevation & avoidance of repeated trauma. • Care of the ulcer by debridement, ulcer cleaning & dressing. • Once the ulcer granulates, defect is Closed with secondary suturing, skin graft (or) flaps.
  • 10. • Pressure sore is tissue necrosis and ulceration due to prolonged pressure. It is more prominent between bony prominence and an external surface. • They can appear & extend rapidly in immobile patients and in those with debilitating illness. • It can also be called as – • Trophic ulcer. • Neuropathic / Neurogenic ulcer. • Bed sore & • Decubitus ulcers. Pressure Sore / Ulcer / Injury
  • 11. SITES FACTORS Pressure Sore / Ulcer / Injury • Pressure • Sensory Loss • Anemia • Malnutrition • Moisture • Def. blood supply • Injury
  • 12. Pressure Sore / Ulcer / Injury
  • 13. Clinical Features • Occurs in 5% of in- patients. • Deep punched out edges. • Non-mobile ulcers – bone as its base. Type Investigations • Pus – C/S • Blood tests • Biopsy • X-ray - part Pressure Sore / Ulcer / Injury
  • 14. • Postural changes: - Change in position – once in 2 hours - Lifting limb upwards – 10 s – once in10 mts • Use of – waterbed/air bed/air-fluidized bed. • Special pressure dispersion cushion / foams. • Absorbent porous clothing. • Regular use of talcum powder – skin dry. • Urinary & faecal care. • Good nutrition / Psychological counseling. • Treating the cause – Anemia/Diabetes…. • Antibiotics & Regular dressings - VAC. • Slough excision → skin grafting / flap cover to be done. P U - Treatment
  • 16. • A scar is an area of fibrous tissue that replaces normal skin after an injury. Thus, scarring is a natural part of the healing process. • The remodelling and maturation phase of wound healing results in scar formation. • Scars result from the biological process of wound repair in the skin, as well as in other organs, and tissues of the body. • Exception of very minor lesions, every wound (e.g., after accident, disease, or surgery) results in some degree of scarring. Scar – Introduction
  • 17. • Initially immature scar is formed during remodeling phase; this scar is raised, itchy, hard and pink in colour. • A mature scar is paler, acellular, softer, flat, without itching (diminishes). • An atrophic scar takes the form of a sunken recess in the skin. These are caused when underlying structures are lost. • A hypertrophic scar is excess scar but will not extend beyond the margin of the scar of the original wound. • Keloid is persistent excessive growth of the scar beyond its margin into the adjacent skin. Scar – Types
  • 20. • Hypertrophic scar is excessive formation of abnormal scar tissue which is raised, often vascular but confined within the margin of the original wound; usually its growth stops in 6 months and often regresses spontaneously. • They are more common in areas of increased tension, wounds crossing tension lines, deep dermal burns & wounds left to heal by secondary intention (longer than 3 weeks). Hypertrophic Scar / Keloid • Keloid scars extend beyond the boundaries of the original incision (or) wound, do not spontaneously regress and are difficult to treat. • The etiology is unknown but genetic predisposition is implicated. They often occur because of relatively minor trauma and mainly in those with darker skin pigmentation.
  • 21.
  • 22. Mgt – Algorithm – Hypertrophic Scar
  • 23. Mgt – Algorithm – Keloid
  • 25. • Contracture is the result of a stiffness or constriction of muscles, joints, tendons, ligaments (or) skin that restricts normal movements. • Contracture develops when normally elastic connective tissues become replaced with inelastic fibrous tissues. Contracture • Contractures are either neurally (or) non- neurally mediated - • Neurally mediated – are due to spasticity and are a common sequalae of UMN lesions. • Non-neurally mediated – contractures are due to structural adaptations of soft tissues [Occur in response to prolonged immobilization of soft tissues].
  • 26. • Inactivity & Scarring – from an injury / burn. • Muscular dystrophy. • Cerebral palsy. • Polio. • Rheumatoid arthritis. • L E – plantar flexion, hip flexion & knee flexion contractures are common. • UE – elbow flexion & supination / adduction & internal rotation contractures of shoulder. • Muscles that cross multiple joints – biceps, hamstrings, TFL & gastrocnemius are predisposed to contractures. Sites Types Contracture Causes
  • 27. • Scar contractures can cause severe functional, psychological and aesthetic problems. • Contractures across joints may restrict the range of movement, leading to deformity, impairment and disability. • Surgical contracture release and reconstruction can be an effective treatment option. Release of contracture surgically and use of skin graft (or) "Z" plasty (or) different flaps. • Proper physiotherapy and rehabilitation is essential. Contracture
  • 29. • It is a blind track lined by granulation tissue leading from an epithelial surface into the surrounding tissues. • Sinus means "hollow" or "a bay" (Latin). Sinus / Fistula • It is an abnormal communication between the lumen of one viscus to another or the body surface or between the vessels. • Fistula means "flute" or "a pipe or tube."
  • 31.
  • 34. • Aetiology & treatment of Leg ulcers. • Basic Investigations & treatment aspects of Leg ulcers. • Sites & Factors causing Pressure ulcers. • Staging of Pressure injury | C/F & Treatment of Bedsore. • Scar – Types, Prevention & Treatment of scars. • Difference between Hypertrophic scar & Keloid. • Contracture – Causes, Sites & Types. • Defn – Sinus / Fistula | Causes for its persistent occurrence. To Summarize
  • 36. • List 4 aetiological factors causing leg ulcers. • Mention the staging methods of decubitus ulcer. • Enumerate 3 sites & 3 factors causing pressure injuries. • Write the management algorithm for keloid. • Compare & Contrast hypertrophic scar from keloid. • Outline the various preventive methods of scar formation. • Write 5 causes for persistence of a sinus / fistula. • Mention the various sites & types of contractures. Question Time
  • 37. The drug used for intralesional injection of keloid treatment is – ◼ a) Prednisolone. ◼ b) Triamcinolone. ◼ c) Androgen. ◼ d) Hydrocortisone. ◼
  • 38. A patient with an injury that has full-thickness loss without exposure of underlying bone or muscle is at which of the following pressure ulcer stages? – ◼ a) Stage – 4. ◼ b) Stage – 3. ◼ c) Stage – 2. ◼ d) Stage – 1. ◼
  • 39. Which one of the following is true regarding leg ulcers & their location? – ◼ a) Pressure ulcer – Tip of the toes. ◼ b) Arterial insufficiency – Medial side of leg. ◼ c) Venous insufficiency – Gaiter area. ◼ d) Diabetic ulcer – Above medial malleolus. ◼
  • 40. A hirsute young male has a sinus just above the natal cleft. Which is the most likely diagnosis? – ◼ a) Tubercular sinus. ◼ b) Hidradenitis suppurativa. ◼ c) Fistula-in-ano. ◼ d) Pilonidal sinus. ◼
  • 41. Which one of the following sites is more prone for contracture formation? – ◼ a) Hip flexion. ◼ b) Elbow pronation. ◼ c) External rotation of shoulder. ◼ d) Wrist flexion. ◼
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