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Universal
Times
2019 Annual Report / Vol.61
New Community Members..2
2019 by the Numbers.........3
Program Reports..............4-7
2019 Supporters...............10
College Destinations.........11
Letter from the Chair.........12
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@summerscience
Program blogs:
SSP2019NMT.wordpress.com
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SSP2019UCSD.wordpress.com
Visit us at
summerscience.org
INSIDE
LINKS
01
Twenty Years of an Independent SSP
by Richard Bowdon ’74, Executive Director
Summer 1999 was the last SSP at Thacher School. We alumni knew it to be a
uniquely valuable educational experience, worth saving. So we decided to try to
continue it elsewhere. That meant incorporating as independent nonprofit. Twenty
years ago this fall, five of us filed the paperwork and got to work. We didn’t know
how to run a summer program ... we didn’t even know exactly what about SSP
made it so transformative (what we called the “secret sauce”). So we changed as
little as possible.
Fast forward to 2019. By now we’ve fully deconstructed the recipe. We know what
can be altered: the location, the field of science … and what can’t: the collabora-
tion, the values and traditions, the honor code, the integrated academic and resi-
dential faculty roles. These are essential ingredients in SSP’s design that create its
life-changing impact on young people.
Pros and Cons of Independence
Most academic summer programs are operated by the host campus, and taught
by its faculty. Only a handful of independent programs exist. The Summer
Science Program is not only independent, it’s ultimately controlled by its
“members”: alumni, former faculty, and other supporters.
We are masters of our own fate. We need no one’s permission to maintain SSP’s
values and unique traditions. We can make admissions decisions with absolute
integrity, with no preference for children of donors, Trustees, or other insiders.
By now SSP has existed on seven campuses and in two fields of science: 82
programs over 61 years. In every one, dedicated faculty have done their best to
ensure that all 2,761 participants receive every benefit of the authentic SSP
experience.
Continued on pg. 2
02
04
02
Gillian Andersen The spouse of longtime faculty member Bill Andersen, Gillian leads a workshop
on technical writing for SSPers at New Mexico Tech each summer.
David Essayan David helps us evaluate new project proposals, and since the Biochemistry pro-
gram opened, co-leads a workshop on drug clinical trials with his spouse Susan
Jerian ‘79.
Woody Halsey As the son of SSP’s first Director, the late MacDonald Halsey, Woody literally grew
up with SSP as part of his life and has stayed in touch as an adult.
Tyrone Hayes A longtime and popular guest speaker, Tyrone gives an unforgettable talk on the
environmental effects of the herbicide atrazine.
Michelle Kirchoff A Research Scientist at Southwest Research Institute, Michelle organizes and
leads a workshop on nonlinear orbit dynamics, a natural extension of analytical
orbit determination.
Nina Lanza Nina is a Los Alamos National Lab scientist, and longtime and popular guest
speaker.
Jon Swift The resident astronomer at Thacher School, Jon spearheaded the renovation of
its venerable observatory. In August he led a tour of the observatory for an SSP
‘84 reunion.
Lea Ybarra Lea is former CEO of the Center for Talented Youth at Johns Hopkins. She serves
on the Nominating Committee and as an advisor for strategic planning.
New Community Members Named
SSP’s members are alumni, former faculty, and others recognized by the Board of Trustees as hav-
ing contributed to the program’s success over multiple summers. At its Planning Meeting on Oct. 6,
the Board welcomed these individuals to our extended family:
Our independence has made, and still makes,
that possible. But independence has its
challenges. Here are three:
• We operate without a financial safety net. SSP survived after Thacher only
because individual alumni, parents, and other friends came to its rescue. That
support still keeps us going. If it ever ended, so would SSP.
• Most colleges run their “conference services” as a commercial, for-profit sideline,
charging outsiders what the market will bear.
• We have to find faculty willing to leave their homes, families, and routines for six
weeks.
“In-house” programs don’t face those challenges.
Maybe you can help. Are you, or someone you know, potentially willing and able to teach at SSP in a future
summer, whether in astrophysics, biochemistry, or some field new to us? Can you suggest a potential future
experiment or host campus partner? Email me at execdir@ssp.org. And of course, we always welcome your
financial support, and your time volunteering for a committee or special project. Thank you!
Continued from pg. 1
03
FALL 2019
2019 By the Numbers
How do teens first hear about SSP?
Some find us online, others are told by a parent, teacher or
peer, or by one of our academic partners. A multi-channel
recruiting effort keeps the applicant pool diverse.
How many apply each year?
Applications hit another record of 1,321, for an overall ad-
mission rate of about 11%. That puts a strain on the Admis-
sions Committee but allows maximum flexibility.
Where do the students come from?
Short answer: everywhere. We continue to enroll over a quarter
from California, and half a dozen at each program from outside
the U.S., always including China and India.
Is there any difference between the applicant pools for Astro and Bio?
Each had almost exactly the same number of applicants: just over 650 for 72 spots. Inter-
estingly, more females applied to Bio (55/45), and more males to Astro (64/36). By design
we maintained 50/50 gender balance at every program.
How much does SSP cost?
SSP is relatively long, therefore relatively expensive: $7,150
this year. Like colleges, we determine financial need from
parents’ tax returns. Unlike colleges, we guarantee to meet
all demonstrated need with grants. Total aid has grown with
SSP’s expansion, exceeding $400,000 this year.
SSP in Astrophysics at
New Mexico Institute of Technology
by Dr. Adam Rengstorf, Academic Director
Universal Times
0204
dynamics. I taught astronomy, observational technique,
data reduction, astrometry, photometry, and the Method
of Gauss. Ms. Martinez took care of everything outside
of the classroom with her usual expertise and kindness.
Returning“visiting faculty members”Aaron Bauer‘06 and
Gillian Andersen taught Python and led a workshop on
scientific writing.
We kept the participants busy with 18 problem sets,
observing notebooks, weekly team research reports,
QoDs, and evening tutorials as needed. A problem set or
code was due every night at midnight, except Sundays,
field trips, and other special events.
Suitable near-Earth asteroids were scarce this summer
– I had to fill in with a couple of Mars-crossers – but
we did have two “potentially hazardous”asteroids.All the
teams did very well, especially considering how difficult
some of the asteroids were to image, and more clouds
than last summer.The telescopes at Etscorn Observatory
were in prime condition thanks to its late Director Dan
Klinglesmith, who died of cancer soon after SSP ended.
“Dr. Dan the Astroman,” who helped with all 17 SSPs at
NM Tech, will be sorely missed.
Field trips included White Sands National Monument,the
Very Large Array, Magdalena Ridge Observatory, and the
very cool Astronomical Lyceum run by John Briggs ‘76.
We also visited EMRTC and Santa Fe and did some local
hiking.
Another successful SSP program at New Mexico Tech is
in the books!
The intensity of every aspect of SSP is different from
anything else I have ever experienced. Every part
of SSP has felt like a heightened sense of reality. I
have never worked so hard in my life and yet feel so
refreshed.
			 - Jonah Henry ‘19
After 18 problem sets, 85
observing shifts, 3 dozen
Method of Gauss Python
programs with convergent
solutions, and a dozen team
submissions to the Minor
Planet Center and Orbit
Determination final reports, we
have 36 wonderful new alumni.
Each summer, participants quickly make the program
their own, setting the tone and creating the community.
This summer in particular,I noticed how compassionate
these teens were, working to build each other up and
help each other. They instantly embodied the spirit of
SSP, both academically and personally, and made the
summer smooth and fun.
This was my 6th
summer as NMT Academic Director,
working withAssistantAD WilliamAndersen,and my4th
with SD Barb Martinez.An all-alumni TA corps of Cyndia
Cao ‘12, Anthony Flores ‘14, Descartes Holland ‘12, and
Emma Louden ’15 rounded out the team.Among us, we
had the combined experience of 40 SSPs!
Dr.Andersen taught all the calculus,physics,and orbital
FALL 2019
05
SSP in Astrophysics at the
University of Colorado at Boulder
by Dr. Agnès Kim, Academic Director
On the way back from Lockheed Martin Space Systems,
headquarters of the Juno mission to Jupiter, the bus
overheated, continuing the SSP tradition of being
temporarily stranded.
Our terrificguest speakers included two alumni/Trustees,
Mike Teorodescu ’06 and Doug Duncan ’68. Eric Cornell
spoke for the fourth time, giving an accessible, riveting
lecture on ultracold atoms. Not many high school
students get the chance to chat with a Nobel Laureate!
This summer we asked the Southwest Research Institute
scientists to lead their workshop on nonlinear orbital
dynamics a few days earlier,so participants could include
the results in their final reports.We required Monte Carlo
simulations from every team. Participants again used
Overleaf (LaTeX) to format their reports.
Teaching at SSP is thrilling. We get to create an
environment where everyone can fit in, do real science,
make lifelong friends,and go home with new confidence.
While their academic preparation varied widely, in the
end, all completed the program successfully. The talent
show on the last night climaxed with a TA-led sing-along
and an emotional group hug.
What was initially a daunting experience has
now become perhaps the most defining 6 weeks
of my life. In SSP I experienced my first taste of
being an independent researcher, made friends,
and learnt more about science and myself than I
would have thought possible.
- Avantika Garg ‘19
On July31st
,I reluctantlyreturned 36 changed teenagers
to their families and “normal life.”Through rain or shine
(metaphorically and literally),they had just worked their
way through six weeks of relentlessly collecting and
reducing data, to determine the orbit of their asteroid
and submit their observations to the Minor Planet
Center.
This was my second
year serving as AD at
Boulder, reuniting with
Mike Dubson ’73. We also
welcomedbackTABradley
Emi ’13. Three new TAs,
Helen Cai’15,Julia Wei’14,
and Jerry Xuan ’14, hit the
ground running. Our TAs
bonded with each other and with the participants,each
bringing their personalities into the relationships. They
challenged participants to work up to potential and
offered loads of advice on life in college and beyond. It
was an honor to work with them.
We welcomed a new Site Director, Richard Witt, an
aerospace engineer now teaching physics at Ladue
Horton Watkins High School in Missouri. Rich could do
anything from optimizing roommate assignments to
navigating the Byzantine CU parking bureaucracy. He
brought a fresh perspective, using his experience as a
teacher to anticipate participants’needs.
We got off campus sometimes, to hike the beautiful
foothills nearby, and to visit the pedestrian mall in
downtown Boulder for shopping and swing dancing.
Universal Times
06
SSP in Biochemistry at
Purdue University
by Dr. Mark Hall, Academic Director
due biochem major. Gabby unfailingly set up the labs
every day, preparing reagents, testing equipment and
procedures, and helping participants.
We welcomed guest speakers Warren Rogers’76,Minos-
ca Alcantara, and three Purdue professors: Christina Li
‘03, Pete Pazcuzzi, and Phillip Low. For the third year,
Susan Jerian ‘79 and David Essayan put on a two-day
workshop on clinical trials in drug development. Field
trips to Argonne National Lab, Eli Lilly, Corteva Agri-
science,Indiana Dunes,Turkey Run State Park,and Trop-
icanoe Cove Water Park rounded out the program.
The expression “work hard,play hard”fits every SSP.The
project isn’t easy. This summer mistakes were made:
assays had to be repeated; enzymes became inactive;
mystifying kinetic curves
were occasionally produced.
However, by departure day,
all twelve teams had identi-
fied at least one rational de-
sign for potential fungicidal
compounds to protect crops
from devastating patho-
gens.
As I have come to realize, the SSP experience is much
more than the experimental project.The overall design,
the close community of bright young minds figuring out
science together, makes for a truly unique and memo-
rable summer, emphasized by the abundance of tears
shed as we all said goodbye.
SSP is a journey of discovery, exploration, collabo-
ration, and reflection. SSP has shaped my perspec-
tive, my goals, my aspirations, and my very self. 	
		
- Alex Dong ‘19
In 2019 I was happy to welcome
back Associate AD Stefan Paula and
his computational modeling exper-
tise. New Site Director Debra Arvin
did a wonderful job organizing guest
speakers and field trips, and ensur-
ing participants’ safety, health, and
happiness. She drew from her years
of experience as a high school teacher and basketball
coach, including the “break on 3!” routine to end dinners.
A wonderful TA team held everything together, providing
constant guidance, mentoring, and support. John Whit-
ney anchored the team, in his third summer, training the
other TAs in the fine art of protein biochemistry and ev-
erything else.Kelsey Bullens,a recent graduate from Pur-
due’s biochemistry program,knew the campus inside (the
lab) and out. Julianne Yang fit in right from day 1, putting
her biochemistry undergraduate degree from “the fine
institution” of U Illinois to good use. She ran the daily
QOD contests, the program blog site and Instagram ac-
count,and took most of the photos.Bernardo da Silva’12,
a Princeton molecular biology major, brought his under-
standing of SSP culture and traditions. A huge addition
this year was Lab Assistant Gabrielle Buck, another Pur-
FALL 2019
SSP in Biochemistry at
UC San Diego
by Dr. Betsy Komives and Dr. Martha Oakley, Academic Directors
Together, we did it! Cloning
Mark Hall’s research project
in enzyme modeling and
inhibition wasn’t easy, even
with his lab protocols, lecture
slides, and even three veterans
of SSP ’18 at Purdue. We shared
the Academic Director duties,
assisted in the teaching by
Barry Grant, an expert in bioinformatics and molecular
modeling.Everyone benefitted from the resourcefulness
of Site Director Laura Corley, who, in spite of the
challenges of a new campus, handled the logistics of
field trips, guest speakers, and all the participants’ non-
academic needs.
Four recent college graduates served as our outstanding
TAs: Emily Overway, Joe Forzano,Tyler Natof, and Rachel
Blake. They worked tirelessly as lab instructors, tutors,
and mentors. We never could have gotten through the
project without Emily,who tooka leadership role for both
the academic and residential aspects. Joe’s unflagging
energy and ability to catch on quickly amazed us.Tyler’s
interactions with participants showed quiet perception
and maturity. Rachel navigated the local landscape and
made everything more fun.The challenge of this project
- the need to teach a month’s worth of lab skills each
week - contributed to faculty workdays of 12-15 hours,
including weekends.
Twelve teams of three participants purified a novel
fungal pathogenic enzyme, assayed its activity towards
24 substrates and 11 inhibitors, and then predicted its
structure and compound binding in silico.Several teams
were able to identify an irreversible inhibitor binding
site, using proteomics mass spectrometry. Following
the Purdue tradition, after departure we printed a 3-D
model of each participant’s enzyme and mailed it to
them.
Field trips to Eli Lilly and Vertex opened participants’
eyes to the newest technologies in drug discovery.
Drs. Susan Jerian ’79 and David Essayan presented the
gripping story of how a drug makes it to market. UCSD
Executive Vice Chancellor Elizabeth Simmons ‘80 and
her spouse, physicist R. Sekhar Chivukula ’78, joined us
for dinner one evening.We resumed the old tradition of
Wednesday afternoon beach trips. Our last trip was to
the famed San Diego Zoo.
The hugs and tears on Departure Day,and the follow-up
thank-you notes and emails, told us that despite some
bumps in the road, we managed to give the authentic
SSP experience to these 36 budding young scientists.
I come from a low-income family in an area with
few opportunities. This program has reinvigorated
my interest in a biochemical career and has allowed
me to make friendships that I will never break. In
essence, SSP truly is the educational experience of
a lifetime.
-Harry Heiberger ‘19
07
Letter from the Chair
What a year in astrophysics! The 50th
anniversary of Apollo 11,the Nobel Prize in
Physics for the discovery of exoplanets,and an
image of a black hole attest to the continuing
vibrancy of the first science.
This year’s SSP participants shared in this excitement—honoring a
legacy begun in 1959.The Biochemistry project launched at Purdue
three summers ago,and “cloned”at UC San Diego this past summer,
showed that our “special sauce”isn’t limited to astrophysics.
What’s next? Chief Academic Officer Dr.Amy Barr Mlinar ’94
is now evaluating project proposals in the emerging field of
metagenomics.Exploiting the genomics revolution and big data,
metagenomics promises to be as foundational to 21st-century
biology as Newton’s laws are to physics.
In the lifetimes of SSP’19 alumni,I predict evidence will be
found for extraterrestrial life.Elements of each of these fields
–Astronomy,Biochemistry,Genomics–will be central to this
profound milestone in humankind’s relationship to the universe!
SSP’s future is bright.Thank you for being part of it.
Business Office:
108 Whiteberry Dr
Cary, NC 27519
Address Service Requested
Universal Times
12
by Dr. Michael Weiss ’74, Board Chair

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SSP 2019 Universal Times Annual Report

  • 1. Universal Times 2019 Annual Report / Vol.61 New Community Members..2 2019 by the Numbers.........3 Program Reports..............4-7 2019 Supporters...............10 College Destinations.........11 Letter from the Chair.........12 Moved? Update your contact information: ssp.org/alumni Donate securely to the 2020 Annual Fund: ssp.org/support Join us on Social Media on facebook.com/groups/ sspalum or Instagram @summerscience Program blogs: SSP2019NMT.wordpress.com SSP2019Pur.wordpress.com SSP2019CUB.wordpress.com SSP2019UCSD.wordpress.com Visit us at summerscience.org INSIDE LINKS 01 Twenty Years of an Independent SSP by Richard Bowdon ’74, Executive Director Summer 1999 was the last SSP at Thacher School. We alumni knew it to be a uniquely valuable educational experience, worth saving. So we decided to try to continue it elsewhere. That meant incorporating as independent nonprofit. Twenty years ago this fall, five of us filed the paperwork and got to work. We didn’t know how to run a summer program ... we didn’t even know exactly what about SSP made it so transformative (what we called the “secret sauce”). So we changed as little as possible. Fast forward to 2019. By now we’ve fully deconstructed the recipe. We know what can be altered: the location, the field of science … and what can’t: the collabora- tion, the values and traditions, the honor code, the integrated academic and resi- dential faculty roles. These are essential ingredients in SSP’s design that create its life-changing impact on young people. Pros and Cons of Independence Most academic summer programs are operated by the host campus, and taught by its faculty. Only a handful of independent programs exist. The Summer Science Program is not only independent, it’s ultimately controlled by its “members”: alumni, former faculty, and other supporters. We are masters of our own fate. We need no one’s permission to maintain SSP’s values and unique traditions. We can make admissions decisions with absolute integrity, with no preference for children of donors, Trustees, or other insiders. By now SSP has existed on seven campuses and in two fields of science: 82 programs over 61 years. In every one, dedicated faculty have done their best to ensure that all 2,761 participants receive every benefit of the authentic SSP experience. Continued on pg. 2
  • 2. 02 04 02 Gillian Andersen The spouse of longtime faculty member Bill Andersen, Gillian leads a workshop on technical writing for SSPers at New Mexico Tech each summer. David Essayan David helps us evaluate new project proposals, and since the Biochemistry pro- gram opened, co-leads a workshop on drug clinical trials with his spouse Susan Jerian ‘79. Woody Halsey As the son of SSP’s first Director, the late MacDonald Halsey, Woody literally grew up with SSP as part of his life and has stayed in touch as an adult. Tyrone Hayes A longtime and popular guest speaker, Tyrone gives an unforgettable talk on the environmental effects of the herbicide atrazine. Michelle Kirchoff A Research Scientist at Southwest Research Institute, Michelle organizes and leads a workshop on nonlinear orbit dynamics, a natural extension of analytical orbit determination. Nina Lanza Nina is a Los Alamos National Lab scientist, and longtime and popular guest speaker. Jon Swift The resident astronomer at Thacher School, Jon spearheaded the renovation of its venerable observatory. In August he led a tour of the observatory for an SSP ‘84 reunion. Lea Ybarra Lea is former CEO of the Center for Talented Youth at Johns Hopkins. She serves on the Nominating Committee and as an advisor for strategic planning. New Community Members Named SSP’s members are alumni, former faculty, and others recognized by the Board of Trustees as hav- ing contributed to the program’s success over multiple summers. At its Planning Meeting on Oct. 6, the Board welcomed these individuals to our extended family: Our independence has made, and still makes, that possible. But independence has its challenges. Here are three: • We operate without a financial safety net. SSP survived after Thacher only because individual alumni, parents, and other friends came to its rescue. That support still keeps us going. If it ever ended, so would SSP. • Most colleges run their “conference services” as a commercial, for-profit sideline, charging outsiders what the market will bear. • We have to find faculty willing to leave their homes, families, and routines for six weeks. “In-house” programs don’t face those challenges. Maybe you can help. Are you, or someone you know, potentially willing and able to teach at SSP in a future summer, whether in astrophysics, biochemistry, or some field new to us? Can you suggest a potential future experiment or host campus partner? Email me at execdir@ssp.org. And of course, we always welcome your financial support, and your time volunteering for a committee or special project. Thank you! Continued from pg. 1
  • 3. 03 FALL 2019 2019 By the Numbers How do teens first hear about SSP? Some find us online, others are told by a parent, teacher or peer, or by one of our academic partners. A multi-channel recruiting effort keeps the applicant pool diverse. How many apply each year? Applications hit another record of 1,321, for an overall ad- mission rate of about 11%. That puts a strain on the Admis- sions Committee but allows maximum flexibility. Where do the students come from? Short answer: everywhere. We continue to enroll over a quarter from California, and half a dozen at each program from outside the U.S., always including China and India. Is there any difference between the applicant pools for Astro and Bio? Each had almost exactly the same number of applicants: just over 650 for 72 spots. Inter- estingly, more females applied to Bio (55/45), and more males to Astro (64/36). By design we maintained 50/50 gender balance at every program. How much does SSP cost? SSP is relatively long, therefore relatively expensive: $7,150 this year. Like colleges, we determine financial need from parents’ tax returns. Unlike colleges, we guarantee to meet all demonstrated need with grants. Total aid has grown with SSP’s expansion, exceeding $400,000 this year.
  • 4. SSP in Astrophysics at New Mexico Institute of Technology by Dr. Adam Rengstorf, Academic Director Universal Times 0204 dynamics. I taught astronomy, observational technique, data reduction, astrometry, photometry, and the Method of Gauss. Ms. Martinez took care of everything outside of the classroom with her usual expertise and kindness. Returning“visiting faculty members”Aaron Bauer‘06 and Gillian Andersen taught Python and led a workshop on scientific writing. We kept the participants busy with 18 problem sets, observing notebooks, weekly team research reports, QoDs, and evening tutorials as needed. A problem set or code was due every night at midnight, except Sundays, field trips, and other special events. Suitable near-Earth asteroids were scarce this summer – I had to fill in with a couple of Mars-crossers – but we did have two “potentially hazardous”asteroids.All the teams did very well, especially considering how difficult some of the asteroids were to image, and more clouds than last summer.The telescopes at Etscorn Observatory were in prime condition thanks to its late Director Dan Klinglesmith, who died of cancer soon after SSP ended. “Dr. Dan the Astroman,” who helped with all 17 SSPs at NM Tech, will be sorely missed. Field trips included White Sands National Monument,the Very Large Array, Magdalena Ridge Observatory, and the very cool Astronomical Lyceum run by John Briggs ‘76. We also visited EMRTC and Santa Fe and did some local hiking. Another successful SSP program at New Mexico Tech is in the books! The intensity of every aspect of SSP is different from anything else I have ever experienced. Every part of SSP has felt like a heightened sense of reality. I have never worked so hard in my life and yet feel so refreshed. - Jonah Henry ‘19 After 18 problem sets, 85 observing shifts, 3 dozen Method of Gauss Python programs with convergent solutions, and a dozen team submissions to the Minor Planet Center and Orbit Determination final reports, we have 36 wonderful new alumni. Each summer, participants quickly make the program their own, setting the tone and creating the community. This summer in particular,I noticed how compassionate these teens were, working to build each other up and help each other. They instantly embodied the spirit of SSP, both academically and personally, and made the summer smooth and fun. This was my 6th summer as NMT Academic Director, working withAssistantAD WilliamAndersen,and my4th with SD Barb Martinez.An all-alumni TA corps of Cyndia Cao ‘12, Anthony Flores ‘14, Descartes Holland ‘12, and Emma Louden ’15 rounded out the team.Among us, we had the combined experience of 40 SSPs! Dr.Andersen taught all the calculus,physics,and orbital
  • 5. FALL 2019 05 SSP in Astrophysics at the University of Colorado at Boulder by Dr. Agnès Kim, Academic Director On the way back from Lockheed Martin Space Systems, headquarters of the Juno mission to Jupiter, the bus overheated, continuing the SSP tradition of being temporarily stranded. Our terrificguest speakers included two alumni/Trustees, Mike Teorodescu ’06 and Doug Duncan ’68. Eric Cornell spoke for the fourth time, giving an accessible, riveting lecture on ultracold atoms. Not many high school students get the chance to chat with a Nobel Laureate! This summer we asked the Southwest Research Institute scientists to lead their workshop on nonlinear orbital dynamics a few days earlier,so participants could include the results in their final reports.We required Monte Carlo simulations from every team. Participants again used Overleaf (LaTeX) to format their reports. Teaching at SSP is thrilling. We get to create an environment where everyone can fit in, do real science, make lifelong friends,and go home with new confidence. While their academic preparation varied widely, in the end, all completed the program successfully. The talent show on the last night climaxed with a TA-led sing-along and an emotional group hug. What was initially a daunting experience has now become perhaps the most defining 6 weeks of my life. In SSP I experienced my first taste of being an independent researcher, made friends, and learnt more about science and myself than I would have thought possible. - Avantika Garg ‘19 On July31st ,I reluctantlyreturned 36 changed teenagers to their families and “normal life.”Through rain or shine (metaphorically and literally),they had just worked their way through six weeks of relentlessly collecting and reducing data, to determine the orbit of their asteroid and submit their observations to the Minor Planet Center. This was my second year serving as AD at Boulder, reuniting with Mike Dubson ’73. We also welcomedbackTABradley Emi ’13. Three new TAs, Helen Cai’15,Julia Wei’14, and Jerry Xuan ’14, hit the ground running. Our TAs bonded with each other and with the participants,each bringing their personalities into the relationships. They challenged participants to work up to potential and offered loads of advice on life in college and beyond. It was an honor to work with them. We welcomed a new Site Director, Richard Witt, an aerospace engineer now teaching physics at Ladue Horton Watkins High School in Missouri. Rich could do anything from optimizing roommate assignments to navigating the Byzantine CU parking bureaucracy. He brought a fresh perspective, using his experience as a teacher to anticipate participants’needs. We got off campus sometimes, to hike the beautiful foothills nearby, and to visit the pedestrian mall in downtown Boulder for shopping and swing dancing.
  • 6. Universal Times 06 SSP in Biochemistry at Purdue University by Dr. Mark Hall, Academic Director due biochem major. Gabby unfailingly set up the labs every day, preparing reagents, testing equipment and procedures, and helping participants. We welcomed guest speakers Warren Rogers’76,Minos- ca Alcantara, and three Purdue professors: Christina Li ‘03, Pete Pazcuzzi, and Phillip Low. For the third year, Susan Jerian ‘79 and David Essayan put on a two-day workshop on clinical trials in drug development. Field trips to Argonne National Lab, Eli Lilly, Corteva Agri- science,Indiana Dunes,Turkey Run State Park,and Trop- icanoe Cove Water Park rounded out the program. The expression “work hard,play hard”fits every SSP.The project isn’t easy. This summer mistakes were made: assays had to be repeated; enzymes became inactive; mystifying kinetic curves were occasionally produced. However, by departure day, all twelve teams had identi- fied at least one rational de- sign for potential fungicidal compounds to protect crops from devastating patho- gens. As I have come to realize, the SSP experience is much more than the experimental project.The overall design, the close community of bright young minds figuring out science together, makes for a truly unique and memo- rable summer, emphasized by the abundance of tears shed as we all said goodbye. SSP is a journey of discovery, exploration, collabo- ration, and reflection. SSP has shaped my perspec- tive, my goals, my aspirations, and my very self. - Alex Dong ‘19 In 2019 I was happy to welcome back Associate AD Stefan Paula and his computational modeling exper- tise. New Site Director Debra Arvin did a wonderful job organizing guest speakers and field trips, and ensur- ing participants’ safety, health, and happiness. She drew from her years of experience as a high school teacher and basketball coach, including the “break on 3!” routine to end dinners. A wonderful TA team held everything together, providing constant guidance, mentoring, and support. John Whit- ney anchored the team, in his third summer, training the other TAs in the fine art of protein biochemistry and ev- erything else.Kelsey Bullens,a recent graduate from Pur- due’s biochemistry program,knew the campus inside (the lab) and out. Julianne Yang fit in right from day 1, putting her biochemistry undergraduate degree from “the fine institution” of U Illinois to good use. She ran the daily QOD contests, the program blog site and Instagram ac- count,and took most of the photos.Bernardo da Silva’12, a Princeton molecular biology major, brought his under- standing of SSP culture and traditions. A huge addition this year was Lab Assistant Gabrielle Buck, another Pur-
  • 7. FALL 2019 SSP in Biochemistry at UC San Diego by Dr. Betsy Komives and Dr. Martha Oakley, Academic Directors Together, we did it! Cloning Mark Hall’s research project in enzyme modeling and inhibition wasn’t easy, even with his lab protocols, lecture slides, and even three veterans of SSP ’18 at Purdue. We shared the Academic Director duties, assisted in the teaching by Barry Grant, an expert in bioinformatics and molecular modeling.Everyone benefitted from the resourcefulness of Site Director Laura Corley, who, in spite of the challenges of a new campus, handled the logistics of field trips, guest speakers, and all the participants’ non- academic needs. Four recent college graduates served as our outstanding TAs: Emily Overway, Joe Forzano,Tyler Natof, and Rachel Blake. They worked tirelessly as lab instructors, tutors, and mentors. We never could have gotten through the project without Emily,who tooka leadership role for both the academic and residential aspects. Joe’s unflagging energy and ability to catch on quickly amazed us.Tyler’s interactions with participants showed quiet perception and maturity. Rachel navigated the local landscape and made everything more fun.The challenge of this project - the need to teach a month’s worth of lab skills each week - contributed to faculty workdays of 12-15 hours, including weekends. Twelve teams of three participants purified a novel fungal pathogenic enzyme, assayed its activity towards 24 substrates and 11 inhibitors, and then predicted its structure and compound binding in silico.Several teams were able to identify an irreversible inhibitor binding site, using proteomics mass spectrometry. Following the Purdue tradition, after departure we printed a 3-D model of each participant’s enzyme and mailed it to them. Field trips to Eli Lilly and Vertex opened participants’ eyes to the newest technologies in drug discovery. Drs. Susan Jerian ’79 and David Essayan presented the gripping story of how a drug makes it to market. UCSD Executive Vice Chancellor Elizabeth Simmons ‘80 and her spouse, physicist R. Sekhar Chivukula ’78, joined us for dinner one evening.We resumed the old tradition of Wednesday afternoon beach trips. Our last trip was to the famed San Diego Zoo. The hugs and tears on Departure Day,and the follow-up thank-you notes and emails, told us that despite some bumps in the road, we managed to give the authentic SSP experience to these 36 budding young scientists. I come from a low-income family in an area with few opportunities. This program has reinvigorated my interest in a biochemical career and has allowed me to make friendships that I will never break. In essence, SSP truly is the educational experience of a lifetime. -Harry Heiberger ‘19 07
  • 8. Letter from the Chair What a year in astrophysics! The 50th anniversary of Apollo 11,the Nobel Prize in Physics for the discovery of exoplanets,and an image of a black hole attest to the continuing vibrancy of the first science. This year’s SSP participants shared in this excitement—honoring a legacy begun in 1959.The Biochemistry project launched at Purdue three summers ago,and “cloned”at UC San Diego this past summer, showed that our “special sauce”isn’t limited to astrophysics. What’s next? Chief Academic Officer Dr.Amy Barr Mlinar ’94 is now evaluating project proposals in the emerging field of metagenomics.Exploiting the genomics revolution and big data, metagenomics promises to be as foundational to 21st-century biology as Newton’s laws are to physics. In the lifetimes of SSP’19 alumni,I predict evidence will be found for extraterrestrial life.Elements of each of these fields –Astronomy,Biochemistry,Genomics–will be central to this profound milestone in humankind’s relationship to the universe! SSP’s future is bright.Thank you for being part of it. Business Office: 108 Whiteberry Dr Cary, NC 27519 Address Service Requested Universal Times 12 by Dr. Michael Weiss ’74, Board Chair