[iD]DNA® GUIDE 2015

WHAT WORKS FOR ONE PERSON,
DOES NOT NECESSARILY
WORK FOR ALL.
GENETICS CREATES A NEW CLASS OF ANTI-AGING TECHNOLOGY.
We know that not every skincare product is going to suit everyone,
and this is why there are so many brands out there and literally
thousands of different products.
LIFE IS COMPLICATED, BUT BEAUTY DOESN’T HAVE TO BE.
PERSONALIZED
REALLY PERSONALIZED
idna.works
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No more guesswork, no more buying products that feel like they might help.
THERE IS NO ONE-SIZE FITS ALL FOR OUR CUSTOMERS.
We replaced skincare guesswork with genetically-designed cosmeceuticals OTC (over the counter)
and nutricosmetics supplements programs.
THE RIGHT INGREDIENTS, IN THE RIGHT FORMULATIONS, IN THE RIGHT ORDER.
Science of [DNA] f(x)™ proprietary statistical algorithms grows in accuracy day by day with [iD]DNA®
growing
sample set. 2014 population for Science of [DNA] f(x)™ is about more than 20.000 DNA population wide
samples stored entirely in-house, making [iD]DNA®
ultra-custom biologically active treatments leading
the way in wellness personal genetics predictions.
Science of [DNA] f(x)™ = GENES VS LIFESTYLE
A PERSONALIZED
TREATMENT PLAN
GENES
VS
LIFESTYLE
HOW MUCH OF YOUR SKIN AGING
CAN YOU ACTUALLY CONTROL?
While genetics do play a large role in how quickly you will age, recent research has started
to show that the habits you develop and choices you make throughout life might be even more
telling, so with your genetically customized ANTI-AGING program you can have control over
how your skin ages.
[iD]DNA®
ultra-custom IS SMART SCIENCE
INDIVIDUAL TREATMENT
PROGRAMS THAT PERFORM
AS THEY CLAIM
A SIMPLE, ADVANCED,
PERSONALIZED TREATMENT PLAN
SUITED FOR TODAY BUSY LIVES
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WE FOCUS ON GENES VS LIFESTYLE:
How much of your skin aging can you control?
IF YOU WANT TO STAY YOUNG WITH AGE,
YOU NEED TO KNOW YOUR GENE-EXPRESSION AGE.
LET’S DISCOVER YOUR SKIN IDENTITY!
FIGHTING BACK
AGAINST YOUR EXPIRY
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Aging is a gradual, irreversible process that occurs
as a number of changes in the appearance
and texture of the different skin structures.
Your DNA is the code containing all the information
necessary to our cells to develop over time
[iD]DNA®
IS THE FIRST DNA-PERSONALIZED
ANTI-AGING TREATMENT IN THE WORLD
THE
SCIENTIFIC
APPROACH
DNA CODE
IS THE KEY
6 7[iD]DNA®
ultra-custom

LET’S FOCUS ON
GENES VS LIFESTYLE:
How much of your aging
can you really control?
STAY YOUNG WITH AGE!
DO YOU REALLY KNOW IF YOU’RE YOUNGER
OR OLDER THAN YOUR BIRTH-CERTIFICATE AGE?
DNAge
The first DNA-personalized prescription
strength treatment to help you fight
your SKIN AGING concerns on your
GENE-EXPRESSION AGE.
DNADiet
The DNA-personalized weight loss
management plan to help you manage
successfully your weight on your
GENE-EXPRESSION EATING PROFILE.
DNASport
The first DNA-personalized SPORT
PERFORMANCE optimization plan
to help you choose the sport that best
suits you and improve your performances
to your maximum potential.
DNACell
The first DNA-personalized CELLULITE
treatment to help you fight the severity
stage of your GENE-EXPRESSION
CELLULITE GRADE.
DNAHair
The DNA-personalized HAIR LOSS
treatment to help you fight your
GENE-EXPRESSION HAIR LOSS STAGE.
TURN BACK
THE CLOCK8 9[iD]DNA®
ultra-custom

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ONE-SIZE DOES FIT YOU
ULTRA-CUSTOM
[iD]DNA®
CHALLENGE
Your follow up for evidence-based performance.
[iD]DNA®
technology measures your results and how much you could improve.
Each [iD]DNA®
treatment is engineered on scientific studies (in vivo) clinical efficacy
terms of application and parameterized to individual GENES vs LIFESTYLE guidance.
[iD]DNA®
ASSESSMENT
As you’ve done your simple DNA assessment, you’re ready to discover research-grade lifelong
scientific remarks and suggestions.
[iD]DNA®
GENETIC REPORT
This [iD] GUIDE comes with your [iD] GENETIC REPORT.
Connect to idna.works to create your 15 days-trial of your [iD]DNA®
ultra-custom foundation
treatment.
[iD]DNA®
ULTRA-CUSTOM BIOLOGICALLY ACTIVE TREATMENTS
Your very individual treatment: the right ingredients, intensity, dose, dosage and the right order
depends on your [iD]DNA®
index, a benchmark of individual GENES vs LIFESTYLE expression age.
[iD]DNA®
THE CONCEPT
TREATMENT-PACK
60 days 2 months
120 days 4 months
180 days 6 months
240 days 8 months
CONCERNS
Anti-Aging
Anti-Aging • Weight Loss Management • Cellulite Treatment
Weight Loss Management • Cellulite Treatment • Hair Loss Treatment
Hair Loss Treatment
IT’S TIME FOR YOUR TREATMENT
TO GET PERSONAL
YOUR DNA TEST
Do you want real results?
[iD]DNA®
ultra-custom, the first and only genetically-guided
anti-aging treatment in the world.
Specific concerns.
Individual benefits.
Precision anti-aging treatments.
THE TRUTH
[iD]DNA®
is the only concept to accept the challenge
of proving on you the effectiveness of your personalized
treatment. Change perspective, focus on GENES vs LIFESTYLE
to calculate your gene-expression age (younger or older
than your birth-certificate age?)
REAL SCIENCE. REAL RESULTS.
GET RESULTS
Forget trials and errors. Get results now!
Your [iD]DNA®
ultra-custom treatment plan will provide you:
• THE RIGHT INGREDIENTS
• THE RIGHT FORMULATIONS
• THE RIGHT ORDER
Prescription strength. With no need of prescription.
DNA-PERSONALIZATION
You’re unique and your beauty is unique, only a personalized
treatment will work for you.
[iD]DNA®
ultra-custom is the luxury of a customized
science-based anti-aging program made specifically for you.
Because your genes don’t lie.
[iD]DNA®
YOUR IDENTITY
10 11[iD]DNA®
ultra-custom

DNA-RECOMMENDED ACTIVE INGREDIENTS
CLINICAL PRESCRIPTION
TOPICAL INGREDIENTS NUTRITIONAL INGREDIENTS
ACETIL HEXAPEPTIDE-50
CAPRYLIC/CAPRIC TRIGLYCERIDE (AND) TEPRENONE
CERAMIDE 3 (AND) CERAMIDE 6 II (AND) CERAMIDE 1 (AND)
PHYTOSPHINGOSINE
CHRYSANTHUS BULB EXTRACT
COPPER TRIPEPTIDE-1
DIMETHILMETHOXY CHROMANOL
GLYCOPROTEINS, GLUTAMIC ACID, VALINE, THREONINE
SOY ISOFLAVONES
ISOTHIOCYANATES
L-ASCORBIC ACID 15%
OZONIZED OLEIC ACID
PHYTOCELLTEC MALUS DOMESTICA
PROANTHOCYANIDIN PHOSPOLIPID COMPLEX
TRIPEPTIDE-10 CITRULLINE
HYALURONIC ACID
SODIUM HYALURONATE CROSSPOLYMER
BIOSACCHARIDE GUM-1
SACCARINE ISOMERATE
DMAE-DIMETHYLAMINOETHANOL
HYDROLIZED RICE PROTEIN, GLYCINE SOJA PROTEIN,
SUPEROXIDE DISMUTASE
OLIGOPEPTIDE-68
PALMYTOL TRIPEPTIDE-5
SUPEROXIDE DISMUTASE
ACETYL TETRAPEPTIDE PLATINIUM
NIACINAMIDE
POLLEN EXTRACT (AND) GLYCINE SOJA
GLYCINE SOYA PROTEIN (AND) SUPEROXIDE DISMUTASE (AND)
SODIUM DEXTRAN SULFATE
OLIGOPEPTIDE-34
ACETYL DECAPEPTIDE-3
ALPHA-LIPOIC ACID
ELLAGIC ACID
NIACIN (VITAMIN B3)
SUPEROXIDE DISMUTASIS 560 UI
VITAMIN C
VITAMIN D
BIOTIN (VITAMIN H)
RECOMMENDED BIOACTIVE INGREDIENTS
ACETIL HEXAPEPTIDE-50
Juveleven® is the guardian of your genomic integrity, by protecting and repairing DNA damage
and delays senescence: cell rejuvenation by over 10 years*. Key element in preserving the vital
code. Reverts senescence in fibroblasts.
ACETYL DECAPEPTIDE-3
CG-Rejuline® is a bio-mimetic complex, which prevents the formation of expression lines and
wrinkles, promoting active cell regeneration. It's a new technology that revitalise and regenerate
your skin. CG-Rejuline® strengthens elasticity and improves skin quality, inducing the synthesis of
collagen type I and elastin.
ACETYL GLUTAMYL HEPTAPEPTIDE-1
SNAP-8® is a bio-mimetic epta-peptide safe hi-tech alternative solution to Botox®. Bye, bye
Botox®: SNAP-8® reduces wrinkles up to - 63%, after 28 days application*, without needles.
Maximum efficacy for frown lines, crow's feet, expression wrinkles.
ACETYL HEXAPEPTIDE-8
Argireline® is a bio-mimetic hexapeptide, specific for the correction of eye contour concerns. It
relieves congestion in the eye area; it is active against the formation of edema (swelling) caused
by compromised hemodynamics, against faulty lymphatic circulation, or against high capillary
permeability. This peptide regulates the loss of skin elasticity and the risk of formation of bags
under the eyes. It also reduces dark circles. Clinical tests show that it reduces bags under the eyes
in only 14 days*.
ACETYL TETRAPEPTIDE PLATINIUM
Platinum peptide is a bioconjugated high-tech nanoparticle clinically tested for +280% collagen III
synthesis increase, +250% collagen I synthesis increase, -61% wrinkles reduction, +47% skin
elasticity, +33% skin hydration, after just 30 days application*.
ACETYL TETRAPEPTIDE-2
Uplevity® hi-tech peptide counteract the force of gravity, by increasing collagen and functional
elastin synthesis, and cellular support. It provides a better structure to the dermis improving the
quality of mature skin. Clinically tested for +47,3% collagen I synthesis, +21,7% elastin synthesis.
Uplevity® peptide further contributes to skin firmness by overexpressing genes involved in cellular
cohesion, that are the interface between the actin cytoskeleton and extracellular matrix (ECM)*.
The ultra-personalized treatment plan on your genetic identity
[iD] DNA index [iD] DNA index TARGET Your DNA recommends
59% 69%
The genetic test highlighted a reduced susceptibility to chrono-aging.
This means that your skin properly protects against external agents and will
tend to remain more supple, firm and soft.
24% 36%
The genetic variant analyzed predispose to a reduced state of hydration. Your
skin is less able to retain water, appearing less tonic. Your genetics also expose
skin to the risk of developing intense dryness phenomena and loss of relaxing
capacity.
30% 35%
The genetic variant we detected predisposes to an increased accumulation of
adipose tissue.
Therefore you may experience alterations in the lipid film with typical
manifestations of oily skin and acne.
[1] Wrinkling (firmness + elasticity) ……………………………………………………………………………………………………………………medium risk
[2] Moisturisation (hyaluronic acid potential) ……………………………………………………………………………………increased risk
[3] Skin Hydration (hydro-lipid film) ……………………………………………………………………………………………………………………increased risk
SCIENTIFIC REFERENCES
1. The important role of stratum corneum lipids for the cutaneous barrier function. van Smeden J, Janssens M, Gooris GS, Bouwstra JA. Biochim
Biophys Acta. 2013 Nov 16. doi:pii: S1388-1981(13)00248-5. 10.1016/j.bbalip.2013.11.006.
2. Connective tissue biochemistry of the aging dermis. Age-associated alterations in collagen and elastin.Uitto J.Clin Geriatr Med. 1989 Feb;5(1):127-
47. Review.
3. Effect of the sun on visible clinical signs of aging in Caucasian skin. Flament F, Bazin R, Laquieze S, Rubert V, Simonpietri E, Piot B. Clin Cosmet
Investig Dermatol. 2013 Sep 27;6:221-32. doi: 10.2147/CCID.S44686.
4. 5,7-Dimethoxyflavone, an activator of PPARα/γ, inhibits UVB-induced MMP expression in human skin fibroblast cells.Kim JK, Mun S, Kim MS,
Kim MB, Sa BK, Hwang JK.Exp Dermatol. 2012 Mar;21(3):211-6. doi: 10.1111/j.1600-0625.2011.01435.x.
5. Peroxisomes in dermatology. Part I.Smith KJ, Dipreta E, Skelton H.J Cutan Med Surg. 2001 May-Jun;5(3):231-43. Epub 2001 May 17. Review.
6. The role of manganese superoxide dismutase in skin aging. Treiber N, Maity P, Singh K, Ferchiu F, Wlaschek M, Scharffetter-Kochanek
K.Dermatoendocrinol. 2012 Jul 1;4(3):232-5. doi: 10.4161/derm.21819.
7. Effects of cigarette smoke extracts on the growth and senescence of skin fibroblasts in vitro. Yang GY, Zhang CL, Liu XC, Qian G, Deng DQ.Int J
Biol Sci. 2013 Jun 28;9(6):613-23. doi: 10.7150/ijbs.6162. Print 2013.
8. Endothelial nitric oxide synthase mediates cutaneous vasodilation during local heating and is attenuated in middle-aged human skin. Bruning RS,
Santhanam L, Stanhewicz AE, Smith CJ, Berkowitz DE, Kenney WL, Holowatz LA. J Appl Physiol (1985). 2012 Jun;112(12):2019-26. doi:
10.1152/japplphysiol.01354.2011. Epub 2012 Apr 12.
9. Nitric oxide function in the skin. Cals-Grierson MM, Ormerod AD.Nitric Oxide. 2004 Jun;10(4):179-93. Review.
10. Aging affects the association between endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction in the Korean male
population.Park JE, Lee WH, Hwang TH, Chu JA, Kim S, Choi YH, Kim JS, Kim DK, Lee SH, Hong KP, Seo JD, Lee WR.Korean J Intern Med.
2000 Jan;15(1):65-70.
11. IL-11, IL-1α, IL-6, and TNF-α are induced by solar radiation in vitro and may be involved in facial subcutaneous fat loss in vivo. Li WH, Pappas A,
Zhang L, Ruvolo E, Cavender D. J Dermatol Sci. 2013 Jul;71(1):58-66. doi: 10.1016/j.jdermsci.2013.03.009. Epub 2013 Apr 10.
12. Factors of skin ageing share common mechanisms. Giacomoni PU, Rein G.Biogerontology. 2001;2(4):219-29. Review.
13. Effect of the sun on visible clinical signs of aging in Caucasian skin. Flament F, Bazin R, Laquieze S, Rubert V, Simonpietri E, Piot B. Clin Cosmet
Investig Dermatol. 2013 Sep 27;6:221-32. doi: 10.2147/CCID.S44686.
14. Loss-of-function polymorphisms in the filaggrin gene are associated with an increased susceptibility to chronic
15. irritant contact dermatitis: a case–control study C.M. de Jongh,*_ L. Khrenova,_ M.M. Verberk,* F. Calkoen,* F.J.H. van Dijk,* H. Voss,_ S.M.
John_ and S. Kezic**Coronel Institute of Occupational Health, Academic Medical Centre, University of Amsterdam, P.O. Box 22700, Amsterdam
1100 DE, the Netherlands_National Poisons Information Centre, National Institute for Public Health and the Environment, Bilthoven, the
Netherlands_Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabru¨ck, Osnabru¨ck, Germany
16. Matrix metalloproteinase-3 genotype contributes to age-related aortic stiffening through modulation of gene and protein expression.Medley TL,
Kingwell BA, Gatzka CD, Pillay P, Cole TJ.Circ Res. 2003 Jun 13;92(11):1254-61. Epub 2003 May 15.
17. Molecular pathology of the elastic fibers. Christiano AM, Uitto J. J Invest Dermatol. 1994 Nov;103(5 Suppl):53S-57S. Review.
18. Genotype-activity relationship for Mn-superoxide dismutase, glutathione peroxidase 1 and catalase in humans. Bastaki M, Huen K, Manzanillo P,
Chande N, Chen C, Balmes JR, Tager IB, Holland N Division of Environmental Health Sciences, School of Public Health, University of California-
Berkeley, Berkeley, CA 94608, USA.
19. Genotype-activity relationship for Mn-superoxide dismutase, glutathione peroxidase 1 and catalase in humans.
20. Bastaki M, Huen K, Manzanillo P, Chande N, Chen C, Balmes JR, Tager IB, Holland N. Division of Environmental Health Sciences, School of
Public Health, University of California-Berkeley, Berkeley, CA 94608, USA. Arch Dermatol Res. 2011 Aug;303(6):445-9. doi: 10.1007/s00403-
011-1129-9. Epub 2011 Feb 4.
59% 69%
24% 36%
capacity.
30% 35%
adipose tissue.
59% 69%
24% 36%
capacity.
30% 35%
adipose tissue.
YOUR [iD] GENETIC PROFILE
Gene Cromosome Genotype
FLG Filaggrin 1q21.3 II
MMP3 Stromelysin-1 also called matrix metalloproteinase 3 11q22.2 5A/5A
ELN Elastin 7q11.23 -/A
PPARG Cellular receptor PPARG 3p25.2 CC
SOD Superoxide dismutase 2 6q25.3 TC
GSTT Glutathione S-transferase T-1 22q11.23 INS
GSTM Glutathione S-transferase M-1 1p13.3 DEL
NOS3 Endothelial nitric oxide synthase 7q36.1 5/5
TNFα Endothelial nitric oxide synthase α 6p21.33 GG
EMILIN1 Emilin 1 2p23.3 CG
COL3a1 Collagen 2q32.2 GG
GPX Glutathione peroxidase 3p21.31 CT
HAS1 Hyaluronic acid synthetase 19q13.41 GG
GENETIC EVALUATION DECODING KEY
OPTIMAL genetic function
ALTERED genetic function
ADVERSE genetic function
GENETICAL GUIDANCE FOR YOUR TREATMENT PLAN
The genetic variant analyzed predispose to a reduced state of hydration. Your skin is less able to
retain water, appearing less tonic. Your genetics also expose skin to the risk of developing intense
dryness phenomena and loss of relaxing capacity.
To counter the adverse effects to which your genetics predispose you it is important to follow few
recommendations that may be useful to improve your state of hydration, delaying the onset of
aging phenomena and helping skin remain firmer for longer.
Given that intense exposure to UV rays coming from the sun may cause skin damage, it is
recommendable to use sunscreens and avoid the hours of maximum intensity. UV rays are also
emitted from sunlamps used in tanning treatments.
The best international scientific references recommend you a corrective treatment based on these
suggestions.
Pentavitin® is a 100%-natural ingredient, made in Switzerland, ECOCERT, to feel deep hydration
for 72 hours. Clinically tested to effectively stimulate genes that play a key role in skin barrier
improvement.*
Moreover, to improve the aspects analyzed in this area, the treatment should also include
hyaluronic acid, sodium hyaluronate crosspolymer, biosaccharide gum-1.
Strictly following the treatment plan that you can create with this genetical guidance, the [iD]
DNA index® for SKIN MOISTURISATION will improve up to 36%.
VISIBLE EFFECTS BIOLOGICAL EFFECTS
POSSIBLE SAGGING SKIN IN THE FORM OF UNSIGHTLY WRINKLES
OR EXPRESSION LINES
POSSIBLE PREDISPOSITION TO HYPERSENSITIVE AND REACTIVE
SKIN
INSUFFICIENT INTAKE OF NITRIC OXIDE
POSSIBLE MINOR DEFENSE AND REGENERATION CAPABILITIES
AGAINST EXOGENOUS STIMULI
POSSIBLE MINOR FIRMNESS OF THE DERMIS
AREA [2]
*all clinical data refers to in vitro ed in vivo clinical studies for claim substantiations by the manufacturers, from their product dossier. Data used for internal training on treatment
functionalities and outcomes presentation. Available evidence documentation on request.
GENE-EXPRESSION AGE
VISIBLE EFFECTS BIOLOGICAL EFFECTS
soft skin
[1]
balanced tone and elasticity maintenance
[1]
potential premature skin aging
[2]
possible loss of subcutaneous fat on the face resulting in the
appearance of wrinkles and skin folds
[2]
soft and shiny skin
[3]
proper hydration
[3]
possible sagging skin in the form of unsightly wrinkles or expression
lines
[6]
possible predisposition to hypersensitive and reactive skin
[6]
unaltered hydro-lipid film barrier protection
[4]
good protection against free radicals damage and oxidative stress
[5]
effective elimination of toxic substances
[5]
correct cell regeneration
[1]
protection against external agents
[1]
maintenance of firmness
[1]
possible alteration in the production of pro-inflammatory
cytokines
[2]
risk of developing flogistic phenomena
[2]
fair hydrating ability
[3]
normal ability to retain water
[3]
insufficient intake of nitric oxide
[6]
possible minor defense and regeneration capabilities against
exogenous stimuli
[6]
possible minor firmness of the dermis
[6]
[ ] brackets indicates the number of the area in which the effect of which it refers.
100 OPTIMAL + + Base level FOLLOW UP -- recommended
0 MAXIMUM RISK - - MAXIMUM SUPPORT recommended + +
Your [iD] DNA index*
54%
Determined upon the basis of genetic testing combined with your lifestyle self-optimisation
[2] Moisturisation (hyaluronic acid potential) ……………………………………………………………………………………………increased risk
[3] Skin Hydration (hydro-lipid film) ……………………………………………………………………………………………………………increased risk
[4] Free radicals damage …………………………………………………………………………………………………………… medium risk
[5] Regeneration (vascolarisation + oxygenation) …………………………………………………………………reduced risk
[6] Sensivity + Inflammation …………………………………………………………………………………………………………………………………………reduced risk
*[iD] DNA® index is the benchmark of the Swiss patent pending concept [iD] DNA® ultra-
custom, showing your scoring in terms of GENES vs. LIFESTYLE. [iD] DNA® index is created on
your genetics, balanced by the interference of individual habits by anamnestic self-assessment.
Your area [iD] DNA® index will be processed by the Science of [DNA] f(x)™ to get your
recommended treatment plan.
The scale [iD] DNA® index ranges from 100 to 0.
SNP DETAIL
Gene
HAS1 Hyaluronic acid synthetase
Hyaluronic acid bestows skin the particular properties of plasticity,
strength, and shape retention thanks to its moisturizing ability. In
fact, it is able to bind a large number of molecules of water,
ensuring greater skin hydration.
The presence of a polymorphism at this gene level, may contribute
to a lesser state of hydration of skin.
Your DNA test highlighted the presence of the disadvantageous GG
variant which renders the HAS1 enzyme less functioning. The
reduction of hyaluronic acid which follows causes skin to appear
less hydrated, as it retains less water molecules.
Cromosome Genotype
18 GG
Locus Telomere localisation
18q13.41 13.41
AREA [2]
GUIDANCE FOR YOUR TREATMENT PLAN
ant analyzed predispose to a reduced state of hydration. Your skin is less able to
pearing less tonic. Your genetics also expose skin to the risk of developing intense
mena and loss of relaxing capacity.
adverse effects to which your genetics predispose you it is important to follow few
ns that may be useful to improve your state of hydration, delaying the onset of
na and helping skin remain firmer for longer.
nse exposure to UV rays coming from the sun may cause skin damage, it is
to use sunscreens and avoid the hours of maximum intensity. UV rays are also
nlamps used in tanning treatments.
tional scientific references recommend you a corrective treatment based on these
100%-natural ingredient, made in Switzerland, ECOCERT, to feel deep hydration
inically tested to effectively stimulate genes that play a key role in skin barrier
mprove the aspects analyzed in this area, the treatment should also include
sodium hyaluronate crosspolymer, biosaccharide gum-1.
g the treatment plan that you can create with this genetical guidance, the [iD]
SKIN MOISTURISATION will improve up to 36%.
CTS BIOLOGICAL EFFECTS
KIN IN THE FORM OF UNSIGHTLY WRINKLES
S
SITION TO HYPERSENSITIVE AND REACTIVE
INSUFFICIENT INTAKE OF NITRIC OXIDE
POSSIBLE MINOR DEFENSE AND REGENERATION CAPABILITIES
AGAINST EXOGENOUS STIMULI
POSSIBLE MINOR FIRMNESS OF THE DERMIS
n vitro ed in vivo clinical studies for claim substantiations by the manufacturers, from their product dossier. Data used for internal training on treatment
es presentation. Available evidence documentation on request.
[iD] GENE-EXPRESSION
5
7
6
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Rather than simply focus on an analysis
of your skin health, your [iD]DNA®
provides
active ingredients recommendations, directly
related to your individual requirements.
[iD]DNA®
reveals you the improvement you
can achieve following your [iD]DNA®
ultra-
custom biologically active treatment.
Follow the suggestions to get results!
Our scientific references library is able
to define the relationship between
the active ingredients and the different
genes variations of your genetic profile.
[iD]DNA®
is scientifically backed
by third parties scientific references,
you can find and check them at the end
of your [iD] GENETIC REPORT.
YOUR [iD] GENETIC REPORT
HOW TO READ YOUR
[iD] GENETIC REPORT
1
3
2
4
Your [iD] starts with your [iD]DNA®
index.
All the relevant areas in terms of biological
systems affecting the concerns are detailed
with visible and biological (internal) effects.
In your [iD] GENETIC REPORT, you find:
• GENETIC remarks;
• LIFESTYLE recommendations;
• EXERCISE suggestions;
• NUTRITION recommendations;
• ACTIVE INGREDIENTS that suits most your skin.
This is your genetic profile. All the SNPs
involved are presented in detail with your
genotype and an easy-to-understand
positive/negative rating.
The scientific foundation uncovers your
skin potential. Real science application
reveals your human genomic profile,
for more accurately predicting your
DNA-personalized treatment.
12 13[iD]DNA®
ultra-custom

IN&OUT BENEFITS: + CLINIAge NUTRICOSMETIC
A DNA-personalized and professional-optimized skincare program program designed to work in
synergy at the cellular level to:
• PROTECT SKIN STEM CELLS
• REPAIR DNA
• SMOOTH OUT WRINKLES FROM THE INSIDE OUT
• PROTECT THE YOUTHFUL LOOK AND VITALITY OF YOUR SKIN
FUNCTION
AGE-DEFYING
PRECISION
CORRECTIVE
INVERTAGE
AVERAGE DURATIONS
60 days 2 months treatment
60/120 days 2-4 months treatment
IN&OUT
SUGGESTED
OPTIONAL
SUGGESTED
MANDATORY
Just log on with your [iD] code to find out you DNA-personalized program:
PREMIUM SWISS SKINCARE TECHNOLOGY
THE SCIENCE OF AGELESS SKIN: 3+
5
REPAIRS, REJUVENATES AND TRANSFORMS SKIN.
PREMIUM
SWISS SKINCARE
CLEANSE
FOUNDATION TREATMENT: CLINILift
+ PRESCRIPTION STRENGTH: booster
PRECISION TREATMENT: CLINIUV A-B
CLEANSE
PRIMARY ACTIVATION: CLINICo2
A,
CLINICo2
B
FOUNDATION TREATMENT: CLINIGf DNA
+ PRESCRIPTION STRENGTH: booster
PRECISION TREATMENT: CLINIEye_5
INTENSIVE CARE: CLINIFace
(Eye) therapy
33
22
11
4
5
every
2 weeks
every
10 weeks
idna.works
FORGET TRIALS AND ERRORS
GET RESULTS NOW!
[iD]DNA®
ultra-custom represents an unprecedented approach to skin aging.
Your personalized skincare program started with your [iD]DNA®
test.
• BY TAKING THIS SIMPLE TEST, you unlock the secrets to your skin’s genetic strengths
and weaknesses.

• BY TESTING YOUR DNA, now you can scientifically select the professional strength
treatment that will most benefit your skin’s beauty and health.
ENJOY YOUR 15 DAYS DNA-PERSONALIZED
FOUNDATION TREATMENT TODAY!
AFTER YOUR FIRST 15 DAYS PROGRAM, TO GET
YOUR COMPLETE DNA-PERSONALIZED TREATMENT:
connect to idna.works
just enter your [iD]code
select the signs of aging you want to fight in YOU+
online adjustment
It’s easier than you think and it takes only 5 minutes.
2
1
3
YOUR [iD]DNA®
IDNA.WORKS
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14 15[iD]DNA®
ultra-custom

ALL THE ACTIVE INGREDIENTS ARE SELECTED TO ENSURE
AN UNPRECEDENTED COSMETOGENOMICS EFFICACY:
EXTENDS CELL VITALITY AND LONGEVITY
Reactivating cells regeneration and renewal in the basal layer of epidermis,
leading to a higher keratinocyte production. The epidermal tissue becomes
thicker, denser and more resistant to external aggressions.
STRENGTHENS THE EXTRACELLULAR MATRIX
Restoring the dermo-epidermal junction and stimulates fibroblasts achieving
an increase in the quality and amount of collagen and elastin.
The skin recovers elasticity and firmness, facial oval has a new sustain
and expression lines decrease substantially.
CELL REGENERATION AND REPAIR
Protecting and reactivating your own dermo-epidermal stem cells, with
selected biomimetic peptides and plant stem cells extracts, strengthening
the connective tissue structure an improving skin quality and texture.
INTELLIGENT ANTIOXIDANT ACTION
Neutralising free radicals contributing to improve the skin’s defence capacity
and delays the skin aging process.
HIGH-TECH COSMETIC ENGINEERING
Encapsulating biomimetic peptides, functional ingredients, plant stem cells
in release biovectors to transport them and act in the innermost skin.
They mimics, in their composition and structure, the cell membrane,
increasing the penetration and diffusion levels.
CLINICare®
cliniceuticals is our brand of unique formulations
for genetically-guided individual treatments,
built just for the [iD]DNA®
ultra-custom concept.
+ PATENTED SCIENCE
+ PROPRIETARY FORMULATIONS
Proprietary formulations
Scientifically formulated from researchers for targeted efficacy
CLINICare®
CLINICEUTICALS
1716 [iD]DNA®
ultra-custom

To make you sure about getting the best results of your [iD]DNA®
ultra-custom biologically active
treatment, we put your smartphone in charge as your personal assistant:
check your [iD]DNA®
ultra-custom treatment plan:
THE RIGHT INGREDIENTS
THE RIGHT FORMULATIONS
THE RIGHT ORDER
[iD]DNA®
ultra-custom app will remind you all your treatments with your personalized dose,
at the right moment.
SCIENCE OF [DNA]
WHAT NEXT?
YOUR TREATMENT
AT YOUR FINGERTIPS!
SEE THE REAL RESULTS!
[iD]DNA®
CHALLENGE
When you’re about to end your treatment, your [iD]DNA®
follow up will check your
[iD]DNA®
indexes to show how much you really improved.
COMBINATION THERAPY
DNA
ASSESSMENT
ACTIVE TREATMENTS
cliniceuticals
FOLLOW UP
cliniceuticals
COLLECTIONS
ANTI-WRINKLE
TIGHTEN & LIFT
REJUVENATION
PRECISION
professional strength
ACTIVE INGREDIENTS
TRYLAGEN®
functional
SNAP-8®
peptide
MATRIXYL-3000®
peptide
JUVELEVEN®
peptide
UPLEVITY®
peptide
RELISTASE®
peptide
DMAE
EGF
COPPER-peptide 1
PLATINUM-peptide
REJULINE®
peptide
PREREGEN®
functional
ARGIRELINE®
peptide
BONT-peptide®
SYN-AKE®
peptide
SENESTEM®
functional
DERMCOM®
functional
BENEFITS
• diminishes length and depth
of lines and wrinkles
• stimulates collagen regeneration
for healthy, younger looking skin
• tightens and firms skin
• restores elastin to create lift
and contour
• intelligent antioxidant action
• free radicals and sun damage
protection, DNA repair
• moisturisation and skin protection
• renews skin smoothness
• refines skin texture
• reveals skin radiance
• revitalizes skin tone
• intelligent antioxidant action
• corrects eye bags, puffy eyes
SUSTAINABLE
SAFE HI-TECH
COSMECEUTICALS
PARABEN
PHTALATE
SLS
COMEDOGENIC
ANIMAL INGREDIENTS
ARTIFICIAL COLORS
NOFREE
AGE-DEFYING
SKINCARE
18 19[iD]DNA®
ultra-custom

CHRONO-AGING depends on genetic factors
specific to each of us. It begins after the age
of 25, and it may be visibly manifested from
40 years onwards.
We observe at the level of the epidermis a lower
ability of cells to regenerate with consequent
thinning of the skin layer.
Even the skin glands are gradually reducing
their activity, resulting in reduced production
of sebum and increased skin dryness.
Aging is also induced by environmental factors
such as pollution, stress, unbalanced diets
or exposure to irritants and harmful substances
such as cigarette smoke.
in particular, a very important role is played
by PHOTO-AGING, which is a chronic and
premature aging of the skin due to prolonged
exposure to sunlight and to the formation
of free radicals.
Today, aging is worsen by TECHNOLOGICAL
AGING, the aging process caused by
electromagnetic waves of iphones, mobile
phones, ipads,computers, constantly attacking
skin moisturisation and hydration barrier.
With the passage of time, the skin may experience skin aging, i.e.
a series of physiological changes that lead to an increased occurrence
of micro-wrinkles, loss of elasticity, and skin dryness.
These changes are mainly due
to two parallel events:
CHRONOLOGICAL AGING and
ENVIRONMENTAL FACTORS.
BEFORE AFTER
YOUR DNAge [iD]
Science of [DNA] f(x)™ = [(1+1) x (8+324
+1) x 3)] + 2 = 6.291.512
INDIVIDUAL TREATMENT
COMBINATIONS
WRINKLING
Firmness + Elasticity
MOISTURISATION
Hyaluronic Acid
Potential
HYDRATION
BARRIER
Hydrolipid Film
REGENERATION
Vascolarisation +
Oxigenation
SENSITIVITY +
INFLAMMATION
FREE RADICALS
DAMAGE
FLG1
1q21.3
MMP311
11q22.2
ELN7
7q11.23
EMILIN12
2p23.3
COL3a12
2q32.2
SOD6
6q25.3
GSTM1
1p13.3
GSTT22
22q11.23
GPX3
3p21.31
LET’S CALCULATE
YOUR GENE-EXPRESSION AGE
Are you younger or older than your birth-certificate age?
Everyone’s skin is unique, as are their fingerprints and genetic code.
Your biological and emotional life can be read on your skin.
Your skin talks your story.
HAS119
19q13.41
PPARG3
3p25.2
NOS37
7q36.1
TNFα6
6p21.33
20 21[iD]DNA®
ultra-custom

Nutrigenetics is a new discipline
that seeks to explain how
the substances we ingest
are metabolized and used,
based on our genes.
The study of DNA makes it possible
to determine the exact amount
of nutrients that each of us requires
and the reaction you’ve to different
dietary components.
DNADiet IS NOT A DIETARY PLAN
DNADiet PROVIDES SPECIFIC
NUTRITIONAL RECOMMENDATIONS
FROM YOUR DNA
No more dieting, but healthy eating:
know yourself to take care of yourself
YOUR DNADiet [iD]
With this test we have analyzed some variations present in
16 GENES, which are involved in the metabolism of foods,
and play an important role in determining your body health:
• FATS ABSORBTION
• LIPIDS AND GLUCOSE METABOLISM
• FATS MOBILIZATION AND LIPIDS METABOLISM
• FATS REGULATION AND BREAKDOWN OF STORED FAT
• FATS METABOLISM AND BODY FAT LOSS
• BONES HEALTH
• SENSITIVITY TO CAFFEINE, ALCOHOL, SALT HYPERTENSION
CAN YOU EAT WHAT YOU
LIKE, MANAGING SUCCESS-
FULLY YOUR WEIGHT?
It is scientifically proven that good nutrition can improve the state
of your health, reducing the risk of many diseases, as well
as chronic ones. But there are no dietary rules that are the same
for everyone, just as there are no diets that work for everyone.
FTO16
16q12.2
ACE17
17q23.3
IL101
1q32.1
TNFα6
6p21.33
CYP1a215
15q24.1
VDR12
12q13.11
APOC311
11q23.3
LPL8
8p21.3
GSTM1
1p13.3
GSTT22
22q11.23
CYP1a215
15q24.1
SOD6
6q25.3
MTHFR1
1p36.22
LCT2
2q21.3
VDR12
12q13.11
DQ2/86
6p21.32
ACE17
17q23.3
BODY FAT LEVELS
AND SUGGESTED
EXERCISE
INFLAMMATORY
RESPONSE
SENSITIVITY
TO CAFFEINE
LIPIDS
METABOLISM
GLYCEMIC
LEVELS +
CARBOHYDRATES
METABOLISM
B VITAMINS
METABOLISM
LACTOSE
INTOLERANCE
D VITAMIN
METABOLISM
Bone Health
PREDISPOSITION
TO CELIAC DISEASE
Gluten Tolerance
SENSITIVITY
TO SALT
Hypertension
DETOXIFICATION
ABILITY
ACE17
17q23.3
PPARG3
3p25.2
TCF7L210
10q25.2-3
22 23[iD]DNA®
ultra-custom

Your genes play a key role in biological systems,
like muscle formation, oxygenation of blood and tissues,
and metabolism of lactic acid. Although you cannot
change your genetic profile, you can benefit from your
genetic advantages and maximise your potential.
YOU CAN OVERCOME THE PAIN
FROM INTENSE EXERCISE AND
PRESSURE UNDER COMPETITION.
YOU CAN BETTER AVOID INJURIES.
Since the diet of athletes is a significant
factor for their performance, we’re releasing
DNASport POWER
and DNASport ENDURANCE
containing also genetic factors which
affect athletes’s power and endurance
performance nutritional and recovery needs.
MORE THAN JUST A TRAINING PLAN
YOUR DNASport PERFORMANCE
ANALYSES GENES FOR CERTAIN
MUTATIONS ASSOCIATED
WITH ATHLETIC PERFORMANCE,
ALL DOCUMENTED IN SCIENTIFIC
LITERATURE.
YOUR DNASport [iD]
SPORT
INJURIES
SPORT
PERFORMANCE
TRAINING
& RECOVERY
ARE YOU BETTER SUITED
TO SPORTS REQUIRING
ENDURANCE, STRENGTH OR SPEED?
Choose a sports that suits you. Learn how your can improve
your sport performance, following your genetic advantages.
Identify your athletic strengths and weaknesses.
ADRB25
5q31
AGT1
1q42.2
ACE17
17q23.3
BDRK214
14q32.1
MSTN2
2q32.2
ACTN311
11q13.1
VEGF6
6q21.1
PPARGα
4p15.2
GDF520
20q11.2
COL5a19
9q34.2
IL6R1
1q21.3
IL67
7q15.3
CRP1
1q23.2
SOD26
6q25.3
NOS7
7q36.1
25[iD]DNA®
ultra-custom
24

The macroscopic appearance of cellulite is a result of alterations of the connective tissue,
which bestow typically spongy and riddled features on the outer layer of skin,
commonly known as orange peel. But not all cellulite is created equal.
Cellulite is characterized by relief alterations of the skin surface, which give the skin
an orange peel, cottage cheese, or mattress appearance.
Flaccidity, laxity, or sagging of the skin further aggravates relief alterations.
Scientific studies have shown that this type of imperfection may arise in very thin people,
and that, on the contrary, some people who are overweight may not be affected by it.
These data suggested that cellulite is not only linked to incorrect diet and lifestyle, but that
genetic factors may also somehow be involved.
EACH ONE OF US IS DIFFERENT, AND THESE DIFFERENCES ARE DUE,
AT LEAST IN PART, TO OUR DNA THAT WITH ITS MINOR VARIATIONS
ALLOWS US TO DIFFERENTIATE IN AT LEAST 3 ASPECTS:
YOUR DNACell [iD]
HORMONAL FACTORS
Have a dominant role in the formation of cellulite.
INFLAMMATION
Contributes to increased levels of fluid in tissues.
OXYGENATION-VASODILATION-ALTERATION
OF THE MICROCIRCULATION
Some genes may be associated with alterations of the venous
system causing a slowing down of blood flow and stagnation
of fluids in the spaces between cells.
2
1
3
LET’S CALCULATE
YOUR GENE-EXPRESSION
CELLULITE GRADE
Although cellulite is often associated a lack of fitness,
ABOUT 90% OF WOMEN, including thin and athletic morphotypes,
experience some kind of cellulite.
ACE17
17q23.3
HIF1α14
14q23.2
NOS37
7q36.1
ESR16
6q25.1
IL-1a2
2q13
HORMONAL FACTORS
AND GENETIC
PREDISPOSITION
CELLULAR
AND TISSUE
INFLAMMATION
OXYGENATION,
VASODILATATION
AND ALTERATION OF
MICROCIRCULATION
26 27[iD]DNA®
ultra-custom

ARE YOU GENETICALLY
PREDISPOSED TO HAIR LOSS?
Your DNA determines when you start showing hair loss, if this is androgenetic alopecia
or just stress, how quickly and at what rate your alopecia could worsen as becoming irreversible
baldness, which is unique to you.
Your DNAHair profile will detail your risk of irreversible androgenetic alopecia and the best
corrective professional treatment, so that you can take action straight away.
ARx
Xq12
EDA2Rx
Xq12
20p1120
20p11
GPX3
3p21.31
OXIDATIVE
STRESS HAIR
LOSS
GENETIC
PREDISPOSITION
Androgenetic
Alopecia
YOUR DNAHair [iD]
idna.works
[iD]DNA®
test, genetic report and treatments are not intended, and should not be used, to diagnose or treat any diseases or medical conditions.
[iD]DNA®
is a exclusive swiss patented pending concept, covered by international trademarks and intellectual property rights protection worldwide.
[iD]DNA®
and all its brands, trademarks, products and materials belong exclusively to Suisse Life Science SA and are to be used for informational purposes only.28 [iD]DNA®
ultra-custom

[iD]DNA® GUIDE 2015

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[iD]DNA® GUIDE 2015