Raynaud's disease.pptx

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SubhashreeMahapatro

it is a recurrent vasospasm of fingers & toes in response to cold and stress.

Health & Medicine

Etiology
• Rheumatoid arthritis.
• Atheroscleosis
• Cryglobulinemia
• Polymyositis
• Buerger’s disease
• Autoimmune disorder
• Injuries to the hands and feet.
• Repetitive actions such as typing and vibrating tools.
• Smoking
• Living in a cold climate
• Certain medications

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A. Standard Precautions-Standard precautions are to be followed for all patients, irrespective of their infection status. These are to be used to avoid contact with blood, body fluids, secretions and excretions regardless of whether contaminated grossly with blood or not; non intact skin; and mucous membrane. They are the basic level of infection control precautions which are to be used, as a minimum, in the care of all patients Infection control measure to be undertaken by hospital- Use standard precaution for the care of all patients. This general mandate is necessary because it is sometimes not known if the patient is colonized or infected with certain pathogenic microorganisms. Barrier precautions reduce the need to handle sharps. B. Transmission Precautions- The second tier condenses the disease-specific and categories approach to isolation into new transmission categories to be taken based on the route of transmission of organisms like contact precautions, airborne precautions, etc. These precautions are designed for specific patients with highly transmissible pathogens

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Information is the knowledge derived from study, experience or instruction. It can also be defined as a collection of facts or data. Education is both the acquisition of knowledge and experience and the development of skills, habits and attitudes that help a person lead a full and meaningful life. Communication is the interaction between two or more persons that involves the exchange of information between the sender and the receiver. Therefore, information, education and communication are closely related to health and play a vital role in creating awareness about health, mobilizing people and making them knowledgeable about health-related factors through efficient mass communication methods.

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Attitude is the bridge between knowledge and practice. Thus assessment of attitude becomes an integral part of student evaluation. Nursing is such a profession where nurses deal with the patients who are in need. So attitude of the nurses really matters to the quality of care they provide. Not only helping the student nurses to develop a healthy attitude, but assessing the same is also an important role of an educator. Unless assessed, we will not know if the students have developed appropriate attitude to enhance their profession. The assessment of attitude is essentially by observation of verbal and nonverbal behavior of the student and is likely to be very subjective. However, development of various attitude scales has reduced its subjectivity. types- There are two attitude scales commonly used to assess the attitude of individuals: Likert scale and semantic differential scale. Likert scale was named after a psychologist Rensis Likert, who developed it in 1932 as a psychological concept measurement scale. Likert scale is the most commonly used scaling technique. It was developed to measure the attitudes, values and feelings of people. Primarily, the original version of this scale was developed with a five-point scale (strongly agree, agree, uncertain, disagree and strongly disagree) containing a mixture of positive and negative declarative statements regarding measuring variables. However, one can even observe the Likert scale now with four point (strongly agree, moderately agree, disagree and uncertain) to seven point (very strongly agree, strongly agree, agree, uncertain, disagree, strongly disagree and very strongly disagree) scaling categories. Semantic differential scale measures individual's attitude toward objects, events or another individual. Respondents describe their feelings on scales with semantic labels. When bipolar adjectives are used at the end points of the scales, these are termed semantic differential scales. This scale consists of a series of contrasting adjective pairs (good- bad, beneficial- harmful) listed on opposite ends of the bipolar scale. The individual is given instruction to quickly tick on or in between the opposite adjective pairs. Scoring is done thereafter by adding the construct on each statement (one to seven).

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Blood glucose concentration in a normal adult remains in the range of 60-100 mg/100 ml. When the value exceeds, it is called hyperglycemia. Persistent hyperglycemia may be a result of diabetes mellitus, which is detected by estimating blood glucose concentration during fasting. To confirm the diagnosis, fasting and postprandial (after meals) samples are analyzed. Sometimes, it may also be essential to perform glucose tolerance test (GTT).

OGTT.pptx

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Biomedical importance- The study of carbohydrates is necessary because they have many important functions in our body. Some examples are as follows:Carbohydrates are major dietary components, which meet 60-70% of our energy requirement. These are starch, sucrose, lactose, etc.Carbohydrates are important constituents of glycoproteins and proteoglycans in cells, tissues and organs. Carbohydrates are used to synthesize many compounds like fats, amino acids, etc. Studying the composition of carbohydrates requires the study of the chemical nature and structure of carbohydrates commonly used. "Carbohydrates are aldehyde or ketone derivatives of polyhydroxy alcohols." The simplest carbohydrates known in nature have 3-carbon atoms and are found both as aldehydes (aldose) and ketones (ketose). Depending on the number of carbon atoms, carbohydrates are called triose, tetrose, pentose, hexose, heptose, etc. having 3, 4, 5, 6 and 7 carbon atoms respectively. However, each can exist both as an aldehyde derivative i.e. aldose, and as a ketone derivative i.e. ketose Carbohydrates are commonly referred to as 'sugars' as many of them are sweet in taste such as sucrose, glucose, etc. But all carbohydrates are not sweet in taste, e.g. starch, cellulose etc. functions- 1. They are the most abundant dietary source of energy (4 Cal/g) for all organisms. 2. Carbohydrates are precursors for many organic compounds (fats, amino acids). 3. Carbohydrates (as glycoproteins and glycolipids) participate in the structure of cell membrane and cellular functions such as cell growth, adhesion and fertilization. 4. They are structural components of many organisms. These include the fiber (cellulose) of plants, exoskeleton of some insects and the cell wall of microorganisms. 5. Carbohydrates also serve as the storage form of energy (glycogen) to meet the immediate energy demands of the body.

carbohydrate.pptx

SubhashreeMahapatro

Buffer-It is a solution of weak acid/base & it’s corresponding salt which resists a change in pH when a small amount of acid or base is added to it. By buffering mechanism, a strong acid (or base) is replaced by a weaker one. pH, quantitative measure of the acidity or basicity of aqueous or other liquid solutions Blood buffer- 1. A chemical buffer is a system of one or two molecules that acts to resist changes in pH by binding H+ when the pH drops, or releasing H* when the pH rises. 2. The bicarbonate buffer system is the main buffer of the extracellular fluid, and consists of carbonic acid and its salt, sodium bicarbonate. H2CO3+NaHCO3 a. When a strong acid is added to the solution, carbonic acid is mostly unchanged, but bicarbonate ions of the salt bind excess H+, forming more carbonic acid. b. When a strong base is added to solution, the sodium bicarbonate remains relatively unaffected, but carbonic acid dissociates further, donating more H+ to bind the excess hydroxide. c. Bicarbonate concentration of the extracellular fluid is closely regulated by the kidneys, and plasma bicarbonate concentrations are controlled by the respiratory system. 3. The phosphate buffer system operates in the urine and intracellular fluid similar to the bicarbonate buffer system: sodium dihydrogen phosphate (NaH,PO) is its weak acid, and monohydrogen phosphate (Na,HPO,) is its weak base. 4. The protein buffer system consists of organic acids containing carboxyl groups that dissociate to release H+ when the pH begins to rise, or bind excess H+ when the pH declines. Respiratory regulation of PH-The lungs have the ability to exhale CO, which is the substrate for H2CO3 and HCO3. Thus, by regulating the rate of pulmonary ventilation through chemoreceptors, PCO, is regulated by lungs. So, a high PCO, leads to decrease in pH and low PCO, increase in pH. High PCO, stimulates ventilation which results in removal of CO₂ by expiration. Renal Mechanisms of Acid-Base Balance- 1. Only the kidneys can rid the body of acids generated by cellular metabolism, while also regulating blood levels of alkaline substances and renewing chemical buffer components. a. Bicarbonate ions can be conserved from filtrate when depleted, and their reabsorption is dependent on H+ secretion Conservation of Bicarbonate lons b. Type A intercalated cells of the renal tubules can synthesize new bicarbonate ions while excreting more hydrogen ions. Synthesis of New Bicarbonate/Excretion of BufferedH* c. Ammonums are weak acids that are excreted and urine, replenishing the alkaline reserve of the blood. NH4+, Excretion d. When the body is in alkalosis, type B intercalated cells excrete bicarbonate, and reclaim hydrogen ions. Acid base disorder-1. When arterial blood pH rises above 7.45, the body is in alkalosis; when arterial pH falls below 7.35, the body is in acidosis. 2. Most hydrogen ions originate as metabolic by-products, although they can also enter the body via ingested foods. Metabolic acidosis:

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