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Eye Anatomy
& Function
Dr Jie Zhang PhD
Senior Research Fellow
Associate Professor Bruce Hadden
LLD, FRACS, FRANZCO
External ocular appearance
• Transmits and refracts
light from the front to
the back of the eye
• Transparent light path
• Includes structures
that bend light
(refract)
• Converts light energy
into action potentials
transmitted to brain
Key Eye Functions
Layers and chambers of the eye
Fibrous Tunic
Vascular Tunic
Nervous Tunic
Anterior Chamber
Posterior Chamber
Vitreous Chamber
Defining ocular segments
Posterior
segment:
Vitreous,
retina,
choroid,
optic nerve
Anterior
segment:
Structures in
front of
vitreous:
Cornea,
iris,
ciliary body,
and lens
• Oil layer:
• Meibomian glands
• Prevents evaporation
• Water layer:
• Lacrimal glands
• Lubricates
• Allows blinking
• Washes away debris
• Forms smooth surface
• Mucin layer:
• Goblet cells of conjunctiva
• Attaches tear film to eye
• Spreads water evenly
Tear film layers and functions
• Transmits light, transparent
• Collagen and matrix
• Aligned
• Spacing
• Relative dehydration is
maintained by endothelial
cells
• No blood vessels
• Refracts light +40-44 dioptres
• Curvature
• Has different refractive index
from air
Cornea functions
Corneal anatomy
Epithelium:
Barrier to fluid loss and pathogen
penetration
Stroma:
Collagen, ECM, keratocytes
Endothelium:
Maintains relative dehydration
Dense innervation:
Most sensitive organ in the body
Immune privilege
Rapid tearing reflex
The cornea:
Transmits light
Refracts lights
Protects ocular interior
Structure of the crystalline lens
Crystalline Lens: Structure and function
• Composed of α, β, and γ crystallins
(water soluble proteins)
• Transmission of light
• Refraction of light. +17 dioptres
• Variable refraction of light -
accommodation
Cornea 2/3rd and lens 1/3rd refracting power
Accommodation
Far objects:
Ciliary muscle relaxed
(↑ diameter)
Zonules tight
Lens flatter i.e.
distance
Near objects:
Ciliary muscle contracts
(↓ diameter)
Zonules relaxed
Lens increases in convexity
‘accommodation’ i.e. near
Accommodation video
• https://www.youtube.com/watch?v=p_xLO7yxgOk&list=WL&index=3&t=0s
• Search for accommodation reflex on youtube
Emmetropia, Myopia & Hypermetropia
Myopic eye = long, hyperopic eye = short
Emmetropia: cornea/lens/eye length “normal”
Retinal Function
• Photoreceptors: conversion of light into action potentials
• Cones. 6 million. High threshold to light. High acuity. Light adapted (photopic)
vision. Colour vision- 3 types of cones: blue, green, red.
• Rods. 120 million. Low threshold to light. Sensitive to movement. Dark adapted
(scotopic) vision. No colour. Low resolution.
• Synapse with bipolar cells  Retinal ganglion cells  Axons form the optic nerve.
1 million fibres.
Spectral sensitivity ranges (nm)
S (Blue 2%) 400-500nm
M (Green 32%) 450-630nm
L (Red 64%) 500-700nm
RETINAL MICRO-STRUCTURE
RETINAL MICRO-STRUCTURE
RETINAL MICRO-STRUCTURE
Fovea is within the central macula
Temporal Nasal
Superior
Retinal
Detachment
Optic nerve head
and adjacent retina
(Masson’s trichome)
Ciliary Body
• Attachment of zonules (suspensory ligament of lens)
• Accommodation. Ciliary body smooth muscle
• Secretion of aqueous humour: Ciliary epithelium
• Provides nutrition for the (avascular)cornea and lens
• Maintains intraocular pressure
Ciliary processes visible
adjacent to lens in eye
with large iridectomy
Name
these
ocular
structures
The Uveal Tract
The eye’s vascular and immunological pool
Iris
Variable size of pupil (iris diaphragm) with light
level with nearness of fixation
Ciliary Body
Aqueous, accommodation, zonule
Choroid
Nutrition of retina and sclera
The most vascular tissue in the body
Eyelids and conjunctiva
1. Skin
2. Muscles
3. Tarsal plate - mechanical
stability & Meibomian glands
– oil layer of tear
4. Conjunctiva
Attach eyeball to orbit & lids
& permits rotation
Functions: Distribute tears, clear debris, cover eyes
during sleep & prevent evaporation, protect from
foreign bodies via the blink reflex
Meibomian glands
Eyelids
and
conjunctiva
Orbicularis oculi muscle
50 in upper eyelid
25 in lower eyelid
Orbicularis oculi and eyelids
Eye movements
Adduction
Abduction
Elevation
Depression
Intorsion/Internal rotation
Extorsion/External rotation
Annulus of Zinn
Trochlea
Extra-ocular muscles
• Medial rectus. Adducts.
• Lateral rectus. Abducts.
• Superior rectus. Elevates.
• Inferior rectus. Depresses.
• Superior oblique. Intorts. depresses, abducts.
• Inferior oblique. Extorts. elevates, abducts.
Extra-ocular muscles
Innervation of extraocular muscles
Lateral Rectus Muscle 
“Abducts”  Innvervated by
Abducens nerve
= Cranial nerve 6
Superior Oblique Muscle 
Passes through the
“trochlea” 
Innervated by Trochlear
nerve = Cranial nerve 4
The other 4 muscles 
Produce “ocular movements”
 Innervated by Oculomotor
nerve = Cranial nerve 3
Search for ‘extraocular muscles eye anatomy’ on youtube
https://www.youtube.com/watch?v=f_rb6FMVHPk&t=7s
Extraocular muscles video
Tear production and drainage
Upper cannaliculus
Lacrimal sac
Lacrimal duct
Lower cannaliculus
Lacrimal gland
Meibomian glands
Conjunctiva
Visual Pathway
Optic nerve
Optic chiasm
Optic tract
Lateral geniculate
nucleus
Optic radiation
Primary visual cortex
Injuries to Visual Pathway
ON
OT
LGN
OR
1° Visual cortex
Age of onset
Congenital
Age-related
Location
Nuclear sclerotic
Cortical
Posterior
Subcapsular
Cause
Age-related
Traumatic
Diabetic
Cataract of the crystalline lens
Phacoemulsification cataract surgery
Capsulorrhexis Phacoemulsification Injection of foldable IOL IOL in capsular bag
Intra-ocular lens (multifocal and toric)
Long thought extinct
living takahē were
rediscovered in an
expedition led
by Invercargill based
ophthalmologist & ENT
physician Dr Geoffrey
Orbell near Lake Te
Anau in the Murchison
Mountains, in 1948.
The End
Material contained in this lecture presentation
is copyright of The Department of
Ophthalmology, New Zealand National Eye
Centre, University of Auckland, and should not
be reproduced without first obtaining written
permission

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ophthalmology-v-eye-anatomy-and-function.pdf