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Pain DOES NOT BEGIN WITH THE STIMULATION OF RECEPTORS
AND IS NOT THE END PRODUCT OF A LINEAR SENSORY SYSTEM!
@SigMik
Meaks The notoriusWarm-up gig for
What the hell is that?
Oh,
just my mind.
Can I ask you a question?
It depends.
Knowledge is
case specific.
Can I ask you a question?
It depends.
Knowledge is
case specific.
Why does my back hurt?
N=1
PARADOXES
An unacceptable conclusion
Derived by apperently acceptable reasoning
from apperantly acceptable premises
KNOWLEDGE
PARADOXES
Specific cause = specific solution?
The problem is not that nothing works,
The problem is that anything can work
KNOWLEDGE
PARADOXES
The more i learn, the more i fix?
Can everything be fixed?
KNOWLEDGE
PARADOXES
It doesn’t Even have to be true,
But it can still potentially
be of great value
WHY?
How?!
PARADOXES leads to dilemmas
A case for simplicity, but
which simplicity should we listen to?
Simple solutions are everywhere!
Where facts are few, experts are many
The pLot
Is it possible to find sense in chaos?
Depends on certain premises
The pLot
Firstly:
YOU ARE NOT THE CENTER
Of THE UNIVERSE
The pLot
Secondly:
you have to be willing
to live with uncertainty
Accept informed probabilities,
Not definite certainties
Conceptual
hygiene
As little contradiction as possible
”Knowledge is case specific”
”True” knowledge is true
In all landscapes of ”reality”
We need certain models of reasoning
Models are tools for thinking
E.G. THE SAB & BPS model
What is a
Model?
”	
George E. P. Box
What is a GOOD
Model?
”	
George E. P. Box
Explains existing phenomeNon and
provides reliable predictability
Models are tools for thinking
E.G. THE SAB & BPS model
Explains existing phenomeNon and
provides reliable predictability
What is a
Model?
”good”
Essentially,
all models are wrong
but some are useful
”	
George E. P. Box
Therapeutic models – wrong, but useful?
Normative
model
Causal
model
Descriptive
model
How the fuck
Why the fuck
What the fuck
Different situations rests on
different premises
How the fuck
Different situations rests on
different premises
Prescriptive
Based on an assumption
On how the world works
We basically do the same,
but from wildly (?)
Different premises
Normative
model
Why the fuck
Different situations rests on
different premises
history
+ Culture
= Identity
Causal
model
Why the fuck
Different situations rests on
different premises
How to become a man
The etero vs the kaluli
Henrich J, Heine SJ, Norenzayan A. The weirdest people in the world?
Behav Brain Sci. 2010;33(2-3):61–83; discussion 83–135.
Causal
model
Why the fuck
Different situations rests on
different premises
THE SOMATIC
DYSFUNCTION
BLOCKING OF QI
HYPOMOBILITY
SUBLUXATION
TRIGGERPOINT
BREATHING PATTERN
BPS-model
neurobollocks
Causal
model
DESCRIPTIVE
model
WHAT THE FUCK
Different situations rests on
different premises
FIRST OF ALL:
”Before we say something
is OUT of this world,
first make sure that it
is not IN this world”
Michael shermer
WHAT THE FUCK
Different situations rests on
different premises
secondly:
biological plausibility?
Thirdly:
Maybe Interesting,
But So what?
DESCRIPTIVE
model
cultural
consistency
Conceptual
hygiene
prescriptive Basic science
Normative
model
Causal
model
Descriptive
model
cultural
consistency
Conceptual
hygiene
prescriptive Basic science
Normative
model
Causal
model
Descriptive
model
THE SOMATIC
DYSFUNCTION
BLOCKING OF QI
HYPOMOBILITY
SUBLUXATION
TRIGGERPOINT
BREATHING PATTERN
BPS-modellen
BRAINSBRAINS
Why the fuck
Understanding of X, y, Z
Crosses all domains!
How the fuck What the fuck
Normative
model
Causal
model
Descriptive
model
Why the fuck
Understanding of X, y, Z
Crosses all domains!
How the fuck What the fuck
In which domain does the Pain
discussion take place?
Normative
model
Causal
model
Descriptive
model
Why the fuck
How the fuck What the fuck
How much (about reality) do
we need to know??
Normative
model
Causal
model
Descriptive
model
We believe what we do
And we do what we do
Because of our
culture!
What is pain?
Fundamental consequences
Are we machines or ecosystems?
True or false?
Our fMRI study concludes that
participants performing memory tasks
showed activity in the parts of the brain
associated with high sounds,
claustrophobia, colors and farting
CLOCKS vs CLOUDS
Bricks are relevant
for a building
But doesn’t say anything
about the meaning
BILDE -REDS503 @FLICKR
From THE bio-psycho-Social model
To The Socio-Psycho-Biological model?
Biography “becomes” biology
“Gains” (salutogenesis)
Trust
Belonging and
nourishment
Respect
Care
Honour and pride
A life sustaining
physiology of meaning,
belonging and hope
“Drains” (pathogenesis)
Threat and betrayal
Isolation and neglect
Humiliation and
integrity violation
Leaving behind
Guilt and shame
A pathophysiology of
disempowerment and
disadvantage
Linn Getz #CauseHealth
tendencies
The brain paradigm
Is the brain becoming the new spine?
”you have pain because something is
messed up in your spine”
”You have pain because something is
messed up in your brain”
Limitations of language
Do we ALL describe
love, hate, fear & Joy
The same way?
The SAB-model is useful,
but TOO simplistic
so what next?
Limitations of language
New definition of pain?
Pain is
an unpleasant sensory and
emotional experience
associated with actual or
potential tissue damage, or
described in terms of such
damage
Pain is
damage
Limitations of language
New definition of pain?
Pain is a distressing experience
associated with actual or potential
tissue damage with sensory, emotional,
cognitive and social components
Williams	–	2016	–	Upda0ng	the	defini0on	of	pain
Limitations of language
…all DEFINITIONS and models of
understanding are wrong, but...
Different models of understanding
are useful for different purposes
(and different realities)
Limitations of language
Humanistic (clinical) definition
Pain is whatever the person says it is
Limitations of language
Humanistic (clinical) definition
Pain is whatever the person says it is
pain is whatever
the experiencing person says it is,
existing whenever and wherever
the person say it does
Margo McCaffery
Problematic that A person could point at a rock and say ”That is pain”?
TID TID
MA
KE
SD
”THE MODERN BRAIN”
STRESSREGULATION PROGRAMS
ACTION PROGRAMS
PAIN PERCEPTION
Cognitive, sensory and
affective dimensions
Voluntary and involuntary action
patterns. Social communication
and management
Cortisol, noradrenalin,
endorphin levels and
immune system activity
BODY-SELF
NEUROMATRIX
INPUTS TO THE BODY-SELF
NEUROMATRIX FROM:
OUTPUT TO BRAIN AREAS
THAT PRODUCE:
Melzack, Katz; Cogn Sci 2013, 4:1–15@SigMik
The neuromatrix
”SENSORY SIGNALLING SYSTEM”
”THE PRIMITIVE BRAIN”
Is not specific for pain!
TID TID
MA
KE
SD
STRESSREGULATION PROGRAMS
PAIN PERCEPTION
Cognitive, sensory and
affective dimensions
Voluntary and involuntary action
patterns. Social communication
and management
Cortisol, noradrenalin,
endorphin levels and
immune system activity
INPUTS TO THE BODY-SELF
NEUROMATRIX FROM:
OUTPUT TO BRAIN AREAS
THAT PRODUCE:
Melzack, Katz; Cogn Sci 2013, 4:1–15@SigMik
What Goes on here?
COGNITIVE-RELATED BRAIN AREAS
Memories of past experience,
attention, meaning and anxiety
ACTION PROGRAMSEMOTION-RELATED BRAIN AREAS
Limbic system and associated
homeostatic/stress mechanism
SENSORY SIGNALLING SYSTEMS
Cutaneous, visceral and
musculoskeletal inputs
What Goes on here?
Humans are ecosystems
“Brains are necessary,
But not sufficient
For the perception of pain”
”the structure of the neuromatrix is
predominantly determined by genetic factors,
although its eventual synaptic architecture is
influenced by sensory inputs.”
Activity in the water stream
is like synaptic activity
The swirls in the river
Is like “blobs” in the brain
A brain without synaptic activity
Is like a river without water
What pain is not
Pain is not a structural injury
Pain is not brain activity
Pain is not a chemical
So what?
Why does it matter?
If you really understand pain:
Then you’ll always believe people in pain
Then you’ll understand when pain becomes suffering
Then you’ll understand why communication matters
Then you’ll understand why so many treatments fail
Then your management will change
Evidence-based
physiotherapy:
A crisis in movement
Touch people who need touching,
this is therapy. Don’t touch people
who don’t need touching,
this is battery.
Talk with people who need talking
with, this is therapy.
Judge when this becomes
meaningless.
Educate your patient by all means,
but also let them educate you.
The Notorious R. Kerry
Was that it?
I guess

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Painful Paradoxes, Dilemmas & Premises For The Understanding of Pain

  • 1. Pain DOES NOT BEGIN WITH THE STIMULATION OF RECEPTORS AND IS NOT THE END PRODUCT OF A LINEAR SENSORY SYSTEM! @SigMik
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  • 9. What the hell is that? Oh, just my mind.
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  • 11. Can I ask you a question? It depends. Knowledge is case specific.
  • 12. Can I ask you a question? It depends. Knowledge is case specific. Why does my back hurt? N=1
  • 13. PARADOXES An unacceptable conclusion Derived by apperently acceptable reasoning from apperantly acceptable premises
  • 14. KNOWLEDGE PARADOXES Specific cause = specific solution? The problem is not that nothing works, The problem is that anything can work
  • 15. KNOWLEDGE PARADOXES The more i learn, the more i fix? Can everything be fixed?
  • 16. KNOWLEDGE PARADOXES It doesn’t Even have to be true, But it can still potentially be of great value WHY? How?!
  • 17. PARADOXES leads to dilemmas A case for simplicity, but which simplicity should we listen to? Simple solutions are everywhere! Where facts are few, experts are many
  • 18. The pLot Is it possible to find sense in chaos? Depends on certain premises
  • 19. The pLot Firstly: YOU ARE NOT THE CENTER Of THE UNIVERSE
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  • 21. The pLot Secondly: you have to be willing to live with uncertainty Accept informed probabilities, Not definite certainties
  • 22. Conceptual hygiene As little contradiction as possible ”Knowledge is case specific” ”True” knowledge is true In all landscapes of ”reality” We need certain models of reasoning
  • 23. Models are tools for thinking E.G. THE SAB & BPS model What is a Model? ” George E. P. Box
  • 24. What is a GOOD Model? ” George E. P. Box Explains existing phenomeNon and provides reliable predictability
  • 25. Models are tools for thinking E.G. THE SAB & BPS model Explains existing phenomeNon and provides reliable predictability What is a Model? ”good” Essentially, all models are wrong but some are useful ” George E. P. Box Therapeutic models – wrong, but useful?
  • 26. Normative model Causal model Descriptive model How the fuck Why the fuck What the fuck Different situations rests on different premises
  • 27. How the fuck Different situations rests on different premises Prescriptive Based on an assumption On how the world works We basically do the same, but from wildly (?) Different premises Normative model
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  • 29. Why the fuck Different situations rests on different premises history + Culture = Identity Causal model
  • 30. Why the fuck Different situations rests on different premises How to become a man The etero vs the kaluli Henrich J, Heine SJ, Norenzayan A. The weirdest people in the world? Behav Brain Sci. 2010;33(2-3):61–83; discussion 83–135. Causal model
  • 31. Why the fuck Different situations rests on different premises THE SOMATIC DYSFUNCTION BLOCKING OF QI HYPOMOBILITY SUBLUXATION TRIGGERPOINT BREATHING PATTERN BPS-model neurobollocks Causal model
  • 32. DESCRIPTIVE model WHAT THE FUCK Different situations rests on different premises FIRST OF ALL: ”Before we say something is OUT of this world, first make sure that it is not IN this world” Michael shermer
  • 33. WHAT THE FUCK Different situations rests on different premises secondly: biological plausibility? Thirdly: Maybe Interesting, But So what? DESCRIPTIVE model
  • 35. cultural consistency Conceptual hygiene prescriptive Basic science Normative model Causal model Descriptive model THE SOMATIC DYSFUNCTION BLOCKING OF QI HYPOMOBILITY SUBLUXATION TRIGGERPOINT BREATHING PATTERN BPS-modellen BRAINSBRAINS
  • 36. Why the fuck Understanding of X, y, Z Crosses all domains! How the fuck What the fuck Normative model Causal model Descriptive model
  • 37. Why the fuck Understanding of X, y, Z Crosses all domains! How the fuck What the fuck In which domain does the Pain discussion take place? Normative model Causal model Descriptive model
  • 38. Why the fuck How the fuck What the fuck How much (about reality) do we need to know?? Normative model Causal model Descriptive model We believe what we do And we do what we do Because of our culture!
  • 40. Fundamental consequences Are we machines or ecosystems?
  • 42. Our fMRI study concludes that participants performing memory tasks showed activity in the parts of the brain associated with high sounds, claustrophobia, colors and farting
  • 45. But doesn’t say anything about the meaning BILDE -REDS503 @FLICKR
  • 46. From THE bio-psycho-Social model To The Socio-Psycho-Biological model?
  • 47. Biography “becomes” biology “Gains” (salutogenesis) Trust Belonging and nourishment Respect Care Honour and pride A life sustaining physiology of meaning, belonging and hope “Drains” (pathogenesis) Threat and betrayal Isolation and neglect Humiliation and integrity violation Leaving behind Guilt and shame A pathophysiology of disempowerment and disadvantage Linn Getz #CauseHealth tendencies
  • 48. The brain paradigm Is the brain becoming the new spine? ”you have pain because something is messed up in your spine” ”You have pain because something is messed up in your brain”
  • 49. Limitations of language Do we ALL describe love, hate, fear & Joy The same way? The SAB-model is useful, but TOO simplistic so what next?
  • 50. Limitations of language New definition of pain?
  • 51. Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage
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  • 54. Limitations of language New definition of pain? Pain is a distressing experience associated with actual or potential tissue damage with sensory, emotional, cognitive and social components Williams – 2016 – Upda0ng the defini0on of pain
  • 55. Limitations of language …all DEFINITIONS and models of understanding are wrong, but... Different models of understanding are useful for different purposes (and different realities)
  • 56. Limitations of language Humanistic (clinical) definition Pain is whatever the person says it is
  • 57. Limitations of language Humanistic (clinical) definition Pain is whatever the person says it is pain is whatever the experiencing person says it is, existing whenever and wherever the person say it does Margo McCaffery Problematic that A person could point at a rock and say ”That is pain”?
  • 58. TID TID MA KE SD ”THE MODERN BRAIN” STRESSREGULATION PROGRAMS ACTION PROGRAMS PAIN PERCEPTION Cognitive, sensory and affective dimensions Voluntary and involuntary action patterns. Social communication and management Cortisol, noradrenalin, endorphin levels and immune system activity BODY-SELF NEUROMATRIX INPUTS TO THE BODY-SELF NEUROMATRIX FROM: OUTPUT TO BRAIN AREAS THAT PRODUCE: Melzack, Katz; Cogn Sci 2013, 4:1–15@SigMik The neuromatrix ”SENSORY SIGNALLING SYSTEM” ”THE PRIMITIVE BRAIN” Is not specific for pain!
  • 59. TID TID MA KE SD STRESSREGULATION PROGRAMS PAIN PERCEPTION Cognitive, sensory and affective dimensions Voluntary and involuntary action patterns. Social communication and management Cortisol, noradrenalin, endorphin levels and immune system activity INPUTS TO THE BODY-SELF NEUROMATRIX FROM: OUTPUT TO BRAIN AREAS THAT PRODUCE: Melzack, Katz; Cogn Sci 2013, 4:1–15@SigMik What Goes on here? COGNITIVE-RELATED BRAIN AREAS Memories of past experience, attention, meaning and anxiety ACTION PROGRAMSEMOTION-RELATED BRAIN AREAS Limbic system and associated homeostatic/stress mechanism SENSORY SIGNALLING SYSTEMS Cutaneous, visceral and musculoskeletal inputs
  • 60. What Goes on here? Humans are ecosystems
  • 61. “Brains are necessary, But not sufficient For the perception of pain”
  • 62. ”the structure of the neuromatrix is predominantly determined by genetic factors, although its eventual synaptic architecture is influenced by sensory inputs.”
  • 63. Activity in the water stream is like synaptic activity The swirls in the river Is like “blobs” in the brain
  • 64. A brain without synaptic activity Is like a river without water
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  • 66. What pain is not Pain is not a structural injury Pain is not brain activity Pain is not a chemical
  • 67. So what? Why does it matter? If you really understand pain: Then you’ll always believe people in pain Then you’ll understand when pain becomes suffering Then you’ll understand why communication matters Then you’ll understand why so many treatments fail Then your management will change
  • 68. Evidence-based physiotherapy: A crisis in movement Touch people who need touching, this is therapy. Don’t touch people who don’t need touching, this is battery. Talk with people who need talking with, this is therapy. Judge when this becomes meaningless. Educate your patient by all means, but also let them educate you. The Notorious R. Kerry
  • 69. Was that it? I guess