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Lee	
  J,	
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  AL,	
  Allen	
  AM,	
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angiotensin	
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  7,	
  on	
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  learning	
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Lew	
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  Angiotensin	
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are	
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Jul;86(2):344-­‐50.	
  
	
  
Harley	
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(2003)	
  Defective	
  importin	
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  recognition	
  and	
  nuclear	
  import	
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  the	
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  factor	
  
SRY	
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  sex-­‐reversing	
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Lee	
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(2003)	
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inhibitor	
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Albiston	
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  AT4	
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insulin-­‐regulated	
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enhancement.Trends	
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Mansour	
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Offiah	
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dysplasia	
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  Bioactive	
  
angiotensin	
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  Aldosterone	
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Dec;2(4):205-­‐10.	
  	
  
	
  
McDowall	
  SG*,	
  Albiston	
  AL*,	
  Matsacos	
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  Sim	
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  Clune	
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  Mustafa	
  T,	
  Lee	
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Simpson	
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  SY.	
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  Evidence	
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the	
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first	
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Chai	
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  MA,	
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  Matsacos	
  DJ,	
  Mustafa	
  T,	
  Lee	
  JH,	
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Mendelsohn	
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receptor)	
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  human	
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autoradiography.	
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McDowall,	
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  Mertin,	
  S.,	
  Mansour,	
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and	
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  Functional	
  and	
  structural	
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  of	
  wildtype	
  SOX9	
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causing	
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Argentaro	
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and	
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Mertin	
  S,	
  McDowall	
  SG,	
  Harley	
  VR.	
  (1999)The	
  DNA-­‐binding	
  specificity	
  of	
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SOX	
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  Acids	
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Scrofani,	
  SDB,	
  Brereton,	
  PS,	
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  MJ,	
  McDowall,	
  SG,	
  Vincent,	
  GA,	
  Brownlee,	
  
RTC,	
  Hoogenraad,	
  NJ,	
  Sadek,	
  M	
  and	
  Wedd,	
  AG	
  (1994)	
  Comparison	
  of	
  native	
  and	
  mutant	
  
proteins	
  provides	
  a	
  sequence-­‐specific	
  assignment	
  of	
  the	
  cysteinyl	
  ligand	
  proton	
  NMR	
  
resonances	
  in	
  the	
  2[Fe4S4]	
  ferredoxin	
  from	
  Clostridium	
  pasteurianum.	
  Biochemistry,	
  33,	
  
14486-­‐14495.	
  
McDowall,	
  S,	
  van	
  Heeswijck,	
  R	
  and	
  Hoogenraad,	
  N	
  (1990)	
  Site-­‐directed	
  mutagenesis	
  of	
  
Arg60	
  and	
  Cys271	
  in	
  ornithine	
  transcarbamylase	
  from	
  rat	
  liver.	
  Protein	
  Engineering,	
  4,	
  73-­‐77.	
  
Patent:
Anthony	
  L	
  Albiston,	
  Frederick	
  AO	
  Mendelsohn,	
  Sharon	
  G	
  McDowall,	
  Siew	
  Yeen	
  Chai:	
  
Modulation	
  of	
  insulin-­‐regulated	
  aminopeptidase	
  (irap)/angiotensin	
  iv	
  (at4)	
  receptor	
  activity.	
  
January	
  27,	
  2005:	
  US20050020519-­‐A1	
  

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Bibliography - Nephrology
 

publications

  • 1. P U B L I C A T I O N S Lee  J,  Albiston  AL,  Allen  AM,  Mendelsohn  FA,  Ping  SE,  Barrett  GL,  Murphy  M,  Morris  MJ,   McDowall  SG,  Chai  SY.  (2004)  Effect  of  I.C.V.  injection  of  AT4  receptor  ligands,  NLE1-­‐ angiotensin  IV  and  LVV-­‐hemorphin  7,  on  spatial  learning  in  rats.  Neuroscience.;124(2):341-­‐9.       Lew  RA,  Mustafa  T,  Ye  S,  McDowall  SG,  Chai  SY,  Albiston  AL.  (2003)  Angiotensin  AT4  ligands   are  potent,  competitive  inhibitors  of  insulin  regulated  aminopeptidase  (IRAP).  J  Neurochem.   Jul;86(2):344-­‐50.     Harley  VR,  Layfield  S,  Mitchell  CL,  Forwood  JK,  John  AP,  Briggs  LJ,  McDowall  SG,  Jans  DA.   (2003)  Defective  importin  beta  recognition  and  nuclear  import  of  the  sex-­‐determining  factor   SRY  are  associated  with  XY  sex-­‐reversing  mutations.  Proc  Natl  Acad  Sci  U  S  A.  2003  Jun   10;100(12):7045-­‐50.       Lee  J,  Mustafa  T,  McDowall  SG,  Mendelsohn  FA,  Brennan  M,  Lew  RA,  Albiston  AL,  Chai  SY.   (2003)  Structure-­‐activity  study  of  LVV-­‐hemorphin-­‐7:  angiotensin  AT4  receptor  ligand  and   inhibitor  of  insulin-­‐regulated  aminopeptidase.  J  Pharmacol  Exp  Ther.  Apr;305(1):205-­‐11.     Albiston  AL,  Mustafa  T,  McDowall  SG,  Mendelsohn  FA,  Lee  J,  Chai  SY.  (2003)  AT4  receptor  is   insulin-­‐regulated  membrane  aminopeptidase:  potential  mechanisms  of  memory   enhancement.Trends  Endocrinol  Metab.  14(2):72-­‐7.       Mansour  S,  Offiah  AC,  McDowall  S,  Sim  P,  Tolmie  J,  Hall    C  (2002)  The  phenotype  of  survivors   of  campomelic  dysplasia. J  Med  Genet.  39(8):597-­‐602.     Offiah  AC,  Mansour  S,  McDowall  S,  Tolmie  J,  Sim  P,  Hall  CM.(  2002)  Surviving  campomelic   dysplasia  has  the  radiological  features  of  the  previously  reported  ischio-­‐pubic-­‐patella   syndrome.   J  Med  Genet.  39(9)     Mustafa  T,  Lee  JH,  Chai  SY,  Albiston  AL,  McDowall  SG,  Mendelsohn  FA.  (2001)  Bioactive   angiotensin  peptides:  focus  on  angiotensin  IV.J  Renin  Angiotensin  Aldosterone  Syst.   Dec;2(4):205-­‐10.       McDowall  SG*,  Albiston  AL*,  Matsacos  D,  Sim  P,  Clune  E,  Mustafa  T,  Lee  J,  Mendelsohn  FA,   Simpson  RJ,  Connolly  LM,  Chai  SY.  (2001)  Evidence  that  the  angiotensin  IV  (AT(4))  receptor  is   the  enzyme  insulin-­‐regulated  aminopeptidase.  J  Biol  Chem.  Dec  28;276(52):48623-­‐6.  *equal   first  authors     Chai  SY,  Bastias  MA,  Clune  EF,  Matsacos  DJ,  Mustafa  T,  Lee  JH,  McDowall  SG,  Paxinos  G,   Mendelsohn  FA,  Albiston  AL.  (  2000)  Distribution  of  angiotensin  IV  binding  sites  (AT4   receptor)  in  the  human  forebrain,  midbrain  and  pons  as  visualised  by  in  vitro  receptor   autoradiography.  J  Chem  Neuroanat.  20(3-­‐4):339-­‐48.  Erratum  in:  J  Chem  Neuroanat     Jun;21(4):331.       McDowall,  S.G.,  Argentaro,  A.,  Ranganathan,  S.,  Weller,  P.,  Mertin,  S.,  Mansour,  S.,  Tolmie,  J.   and  Harley,  V.R.  (1999)  Functional  and  structural  studies  of  wildtype  SOX9  and  mutations   causing  campomelic  dysplasia.  J Biol Chem. 274(34):24023-30.     Argentaro  A,  Olsson  J,  Critcher  R,  McDowall  SG,  Harley  VR.  (2000)  Genomic  characterisation   and  fine  mapping  of  the  human  SOX13  gene.  Gene.  May  30;250(1-­‐2):181-­‐9.  
  • 2.   Mertin  S,  McDowall  SG,  Harley  VR.  (1999)The  DNA-­‐binding  specificity  of  SOX9  and  other   SOX  proteins.  Nucleic  Acids  Res.  Mar  1;27(5):1359-­‐64.     Scrofani,  SDB,  Brereton,  PS,  Hamer,  AM,  Lavery,  MJ,  McDowall,  SG,  Vincent,  GA,  Brownlee,   RTC,  Hoogenraad,  NJ,  Sadek,  M  and  Wedd,  AG  (1994)  Comparison  of  native  and  mutant   proteins  provides  a  sequence-­‐specific  assignment  of  the  cysteinyl  ligand  proton  NMR   resonances  in  the  2[Fe4S4]  ferredoxin  from  Clostridium  pasteurianum.  Biochemistry,  33,   14486-­‐14495.   McDowall,  S,  van  Heeswijck,  R  and  Hoogenraad,  N  (1990)  Site-­‐directed  mutagenesis  of   Arg60  and  Cys271  in  ornithine  transcarbamylase  from  rat  liver.  Protein  Engineering,  4,  73-­‐77.   Patent: Anthony  L  Albiston,  Frederick  AO  Mendelsohn,  Sharon  G  McDowall,  Siew  Yeen  Chai:   Modulation  of  insulin-­‐regulated  aminopeptidase  (irap)/angiotensin  iv  (at4)  receptor  activity.   January  27,  2005:  US20050020519-­‐A1