Also known as short term memory loss.Although there is no cure, Alzheimer's medications can temporarily slow the worsening of symptoms.

1. Assignment on
Alzheimer’s diseases
Course Title: Pharmacology-11
Course Code: BPH-313
Prepared By:
All An Shariah Brishti
Sec: 13th
(B)
Department of pharmacy
Faculty Of Ailed Health Science
Daffodil International University
Submission Date:15th
April,2017

2. Patient’s data
Name: X
Age: 65
Sex: Female
Symptoms: Memory loss and confusion
Behavioral: Aggression, agitation, difficulty with self-care
Mood: Anger, loneliness
Diagnosis:
 Conduct tests of memory, problem solving, attention, counting, and
language.
 Blood and urine tests, to identify other possible causes of the problem.
 Perform brain scans, such as computed tomography (CT), magnetic
resonance imaging (MRI).
Patient suffer from Alzheimer’s diseases.
Treatment for the patient:
Although there is no cure, Alzheimer's medications can temporarily slow the
worsening of symptoms. Two types of FDA approved drugs used to treat the
cognitive symptoms of Alzheimer’s.
 Cholinesterase inhibitor
 Memantine.
Neurons are the chief cells destroyed by Alzheimer's disease.
In the brain, neurons connect and communicate at synapses, where tiny bursts
of chemicals called neurotransmitters carry information from one cell to

3. another. Alzheimer's disrupts this process, and eventually destroys synapses and
kills neurons, damaging the brain's communication network.
Current FDA-approved Alzheimer's drugs support this communication process
through two different mechanisms:
1) Cholinesterase inhibitors work by slowing down the process that breaks
down a key neurotransmitter. Cholinesterase breaks apart the
neurotransmitter acetylcholine, which is vital for the transmission of nerve
impulses. Donepezil, galantamine and rivastigmine are cholinesterase
inhibitors.
2) Memantine is an NMDA (N-methyl-D-aspartate) receptor antagonist,
which works by regulating the activity of glutamate, an important
neurotransmitter in the brain involved in learning and memory.
Self-care: Aerobic activity for 20-30 minutes 5 days a week improves
cardiovascular health.
Consultation with Occupational Therapist, Geriatrician, Neurologist.
Occupational Therapist: Improves daily living and work skills of patients.
Geriatrician: Focuses on the health care of elderly people.
Neurologist: Treats nervous system disorders.