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Transforming Treatments to Personalized Cure
DiponEd
Dr. Kaushik Deb
Founder, CEO,
Managing Director
Volume01|Issue06|2020
T
H
E10MOST INNOVATIVE
BIOTECHSOLUTION PROVIDERS
TO WATCH IN 2020
one are the days, when Bio
GTech sector was embracing
only traditional processes to
fight the complexities of the disease.
Today, the sector is moving beyond the
'one disease, one protein, one drug'
paradigm by leveraging pipelines
showcasing multiple new-age drug
modalities. These modalities are an
even mix of compound varieties of
traditional protein-enabled molecules –
enzymes, monoclonal antibodies,
hormones, and fusion proteins over a
rapidly transforming area of cell
therapy and Antibody-drug Conjugates
(ADCs).
Currently, the Bio Tech Solution
Providers are putting their best foot
forward in gaining deep biological
insights into tangled diseases. They are
consistently endeavouring to surpass
every challenge coming their way with
sophisticated engineered drugs that
have the potential to save millions of
lives across the globe.
The Bio Tech business professionals
are all set to unlock new business
opportunities alongside disrupt the
healthcare world to stay on top of
different regulatory requirements.
Acknowledging the changing
dynamics of the society and
skyrocketing demands, they are rolling
out patient-centric solutions and
creating a platform of healthy
lifestyles. Besides, it's the right
combination of tech-based
advancements and agile manufacturing
techniques that are taking this sector to
be at the helm of 'Progress’and
‘Innovation’.
Recognizing such professionals that
are revolutionizing the Bio Tech
Solution Providers’ segment and
keeping innovation on their radar by
staying up-to-speed with the
developments, we have come up with
this special edition of “The 10 Most
Innovative Bio Tech Solution
Providers to Watch in 2020”. This
issue has featured a handful of
companies offering a diverse and
engaging mix of commitment and
distinctiveness. It will help you to walk
through a list of experts embracing a
The Changing
Scenario
of Bio Tech
Editor
Rahul Niraj
EDITOR’s
NOTE
multi-disciplinary approach and
covering a range of relevant issues in
its sector.
On the Cover of the issue is DiponEd –
an innovative healthcare biotechnology
R&D driven company. The company is
outshining its competitors with its
innovative solutions and redefining the
Bio Tech segment.
Apart from such an insightful cover
story, we have also enlisted, Bangalore
Bioinnovation Centre (BBC) is a
translational research centre catering to
the needs of startups in the broad areas
of Life Sciences viz., Health Care
(MedTech/ Pharma/ Bio-Pharma),
Agriculture, Food/Nutrition, Industrial
Biotechnology and Environmental
Biotechnology, FastSense Diagnostics
(FSD) has taken the responsibility to
bring in ‘Change’ which the world is
looking forward to, Sisco Research
Laboratories Pvt. Ltd. (SRL) stands
amongst the oldest and most respected
manufacturers of specialty fine
chemicals, microbiological,
nanotechnology and biotechnology
reagents, and Transcell Biolife was
founded to be a biobank for the
intended applications; built on
preservation theme and technology
translated to apply.
Alongside companies like Catalysts
Bio, Clonz Biotech, Cordlife India,
Bioxgreen Technology Private Limited
and Invitrosense (P) Ltd. have also
been featured in the listing of this
edition.
While flipping the pages, take note not
to miss out the exclusive interview
with team Accurex Biomedical Pvt.
Ltd. (ABPL). A CXO named ‘Insights
to Choosing the Right IVF Center’ by
Dr Ritu Hinduja, Senior Consultant
– Reproductive Medicine, Nova IVF,
Andheri (Mumbai) will make you go
gaga.
Turning some more pages will help
you find articles masterly crafted out
by our in-house Editors. These articles
will help you understand the current
market scenario of this industry.
Looking at the emerging opportunities
and the growing possibilities, this issue
of ours will introduce you to a whole
new world of novelty.
So, enjoy the exciting read!
DiponEd
Transforming Treatments
to Personalized Cure
Accurex Biomedical
Testing Life and Saving Lives
Contents
CoverStory
08
Articles
Market Dashboard
Social Media Marketing
for Pharma Industry
Agriculture Biotechnology:
Revolutionizing Agriculture
Process Globally
Agri Tech
22 34
14
Bangalore
Bioinnovation Centre
Helping Innovative
Ideas Hatch
FastSense
Diagnostics
The Next-Gen
Technology for Swift and
Efcient Care
Transcell Biolife
The Next Generation
Biobank with Global
Outlook
Experts Opinion
Insights to Choosing the
Right IVF Center
18
38
28
Sisco Research
Laboratories
A Name Synonymous
to Quality Reagents
and Biochemicals
32
26
SME-SMO Executive Uma
Circulation Manager Tanaji
Digital Marketing Manager Prashant Chevale
Technical Specialist Amar Sawant
Co-designer Mayur Koli
Art & Picture Editor Shweta Ambilwade
Art & Design Head Amol Kamble
Associate Designer Poonam Mahajan
Copyright © 2020 Insights Success Media and Technology Pvt. Ltd., All rights reserved. The content and images used in this magazine should not be reproduced or
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January, 2020
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Editor-in-Chief Pooja M. Bansal
Managing Editor
Shruti, Darshan, SnehaPublishing Control Team
RNI NUMBER: MAHENG/2018/75953
Technical Head Pratiksha Patil
Business Development Lead Ashwini Pahurkar
Sr. Business Development Executive Snehalata Lad
Rahul Niraj
Business Development Manager Megha Mishra
Dr. Kaushik Deb
Founder | CEO | MD
COVERSTORY
Dipon dETRANSFORMING TREATMENTS
TO PERSONALIZED CURE
ealthcare in today’s time has
Hbecome crucial in terms of
accessibility and ease of
facilitation. As new diseases are emerging
from the nooks and corners of the world,
the medical industry with all its dynamism
needs to double down to counter such
diseases in an effective and efficient
manner.
Moreover, to target the specific diseases
while diminishing or eliminating its effects,
the advent of precision medicine is moving
from a niche to a widely accepted method
for treatments. Also known as personalized
medicine, it is moving closer to be precise,
predictable and powerful healthcare
“We help various
companies through
contract manufacturing
of Biologicals at our
Class 10,000 cleaning
room facility”
approach which can be customized for
any individual patient.
Even the world’s best doctors and
scientists don’t completely
comprehend the development of
different diseases in people and their
response to the respective treatments.
The ‘one-size-fits-all’ approach to
medicine has been implemented by lots
of medical and healthcare providers
which is based on broad population
averages. The traditional practices
often misses its mark as each person’s
genetic makeup is quite different from
other people. This very often, can
affect the health of an individual in
important ways.
The growing understanding of genetics
and genomics is enabling the doctors to
provide better disease prevention,
accurate diagnosis, safer drug
prescriptions and effective treatments
for many people. Personalized
medicine is playing a vital role in
tailoring healthcare to every person's
unique genetic makeup. That is the
promising idea behind
precision/personalized medicine. This
approach towards the healthcare
services has revolutionized how the
medical industry works and have
facilitated results that are quintessential
for individual patient’s overall
development.
DiponEd BioIntelligence is an
organization working with such an
approach in the Indian healthcare
domain. It is an innovative healthcare
biotechnology company driven by
strong in-house R&D. It offers
precision and personalized medicine
products, services, and solutions
meeting global standards. The
company is developing a point of care
biological devices for isolation of stem
cells, PRP, Biologicals, Biosimilars,
Neo Antigens, and Cellular therapies.
These therapies include Mesenchymal
Stem Cells, NK Cell & T cell for
cancer, autoimmunity, diabetes,
neurological problems, orthopedics,
infertility, cardiovascular disease,
diabetes, anti-aging, and dermatology,
etc. “We focus on developing the next-
generation bio-intelligent products to
address unmet healthcare needs,” says
the team of DiponEd.
More about DiponEd
DiponEd has also developed a range of
personalized diagnostics and
prognostic tests like liquid biopsies,
gut metagenomics, pesticide tolerance,
genetic predispositions, stress scoring,
3D printed orthotics- prosthetics -
modeling, drug overloads, omics of
diseases, etc. under its brand Merisis
Therapeutics. DiponEd Institute of
Regenerative Medicine has been
offering education in regenerative
medications to clinicians through its
hybrid online and hands-on training
programs.
The company was started in 2010 with
an idea to develop solutions and
treatments for unmet medical needs
like cancer, nonhealing wounds, burns,
muscular dystrophies, autoimmune
conditions like rheumatoid arthritis and
T1 diabetes, and several other
debilitating conditions like ALS, MS,
COPD, ILD, T2 diabetes, etc. The
team at DiponEd soon realized that
prevention is better than cure for most
of these above-mentioned conditions.
Though, integration of preventive,
“Theworldissittingonatimebombofpre-cancer
andpre-l,ldiabeticpatients.Weneed
tostartprogramsthatprovideAtoZsolutions”
predictive, participatory, and
personalized medicine is required to
reach from ‘treatment to cure’. This
could prove to be a major diversion for
current health care treatment business
models.
“We then started working on
developing products and services like
predictive and prognostic genetic and
molecular tests for suspects or
patients, and also personalized
therapeutics,” states DiponEd's team.
The company is currently integrating
many in-house technologies as well as
some foreign service providers to make
an entire ecosystem to develop a
personalized cure for various diseases.
DiponEd-CRS (Contract Research
Services) is a wing of the company,
providing an R&D ecosystem with a
team of highly experienced and
qualified scientists. The wing acts as a
supporting facility for many
international Bio-Pharma companies.
This division offers its services in the
domains of integrated drug discovery
of small molecules in the areas of in-
silico modeling, PK-PD modeling, and
system biology. These services also
facilitate ADME, toxicology, pre-
clinical optimization, in vitro biology
and (Enzyme assays, Cell-based
assays, Ligand binding assays, GPCR,
ELISA) in vivo biology, etc. DiponEd
also provides services in the domain of
Molecular biology, immunogenicity
assays, formulation development and
Regulatory Assistance for the Indian
FDA. DiponEd CRS is an official
empanelled partner to Andhra Pradesh
Medical Tech Zone (AMTZ), Kalam
Institute of Health Technology, for
medical devices and regulatory
support.
Versatile Offerings, Simplified
Services
The power of biotechnology and
biomedical engineering has helped the
company’s R&D team to design
multiple programs targeting cellular
biologicals, stem cell transplantation &
processing protocols, developing
monoclonal antibodies (MAbs) and
cellular therapies. “We design and
create biomaterials using our
proprietary 3D printing technology
and 3D tissue engineering,” states the
team of DiponEd.
The company's focus is on current
personalized medicine which includes
genetic predispositions, mutation
detection, cancer-integrated therapies,
pharmacogenomics-based drug
response tests, anti-aging, stem cells
transplantations in blood-related
disorders, biomaterials, 3D
reconstructions, orthotics, radiation,
chemoprotection, personalization, skin
and hair treatments, infertility and
healthcare products.
DiponEd provides new devices and
technologies along with the solutions
which are developed in-house and are
at feasible costs, usually at a fraction of
the costs from the US or Chinese. The
firm is also integrating all the services
under one roof to emerge as a one-stop
solution provider for personalized
medicine services. The company is
also contributing towards the corporate
social responsibility cause through its
primary health care initiatives at
rural/semi-rural townships. Especially,
in the areas of diabetic foot ulcers and
pain management curated for the
unprivileged section of the society.
Remarkable Footprints
DiponEd emerged as Elevate 100
Award Winner, 2017. It was also
selected as the Emerging Leader in the
Medical Devices industry in India, for
Merisis Therapeutics point of care kits
presented at THE HEALTHCARE-
PHARMA & MEDICAL DEVICES
SUMMIT & EXCELLENCE
AWARDS 2017 on 4th August 2017 at
St. Regis, Mumbai. The firm received
Karnataka State's quality leadership
award, by the World Quality Congress
& Awards in 2019.
Under the leadership of Dr. Kaushik
Deb, Founder, CEO, and Managing
Director of DiponEd – the company
has developed more than 30 patented
products and services. It is
“Our concepts in personalized treatments are new to
the health care ecosystem in India and also in many
parts of the world. We are spending a lot of time and
effort in creating awareness”
collaborating with more than 20
international and National labs and
education institutions to develop its
unique line of therapeutics. He also
established the DiponEd Institute of
Regenerative Medicine (DIRM),
offering Certificate Course in
Regenerative Medicine (CCRM) and
Fellow Program in Regenerative
Clinical Medicine (FRCM) with the
DDM university.
He is the Director of Indian association
of laser therapies (IALT), and
Secretary, Society of Tissue
Engineering and Regenerative
Medicine (India). He has done M.Sc,
MD (IM), Ph.D., Post Doc Associate
(USA, Canada), EGMP (IIM-B) and
FRHS. He has been awarded the Govt
of India DBT's, Overseas Bilateral
exchange Associateship with Ottawa
General Hospital, and the Indian
National Academy of Sciences
(INSA)- bilateral exchange award with
the Czech Science Academy. He has
published over 70 peer-reviewed
research papers, abstracts, and book
chapters, and is also an active reviewer
for 4 international journals and
editorial board member for 5
international journals. He has authored
the book entitled ‘Stem Cells; Basic
and Applications’ published by
McGraw Hill New Delhi and ‘Stem
cell Technologies’ by McGraw Hill,
New Jersey, USA. Dr. Kaushik has
developed/ patented platform
technologies for personal health care
and personalized therapies in cancer,
radiation, hair and skin regeneration,
Oestochondral defects, organ-specific
aging, age-associated conditions,
diabetics AMR, 3D tissue engineering,
etc.
Dr. Kaushik has been awarded the
Govt of India DBT’s, Overseas
Bilateral exchange Associateship with
Ottawa General Hospital, and the
Indian National Academy of Sciences
(INSA)- bilateral exchange award with
the Czech Science Academy. He has
also been honored with MED
ACHIEVERS ICON AWARD for his
work in the field of Healthcare. He and
his team are developing 3D bioprinting
and 3D printing services, under the
'Uchhattar Avishkar Yojana' award,
supported by the Ministry of Health
Government of India.
DiponEd is setting up novel Artificial
“Our vision is to address unmet medical
and healthcare needs across the
globe through innovation, science,
and modern technologies”
intelligence platforms P4M Cure Clinic
and apps, and new algorithms are
being derived to learn about healthcare
and diseases. All of this while creating
integrated clinical data for Predictive,
Preventive, Participatory and
Personalized medicine, in collaboration
with hospitals globally. The R&D team
is working on several unique aspects of
modern health care challenges like
Drug interactions in patients, Drug
overloads, Chemosensitivity, Liquid
biopsies, Genomics, Proteomics,
Metabolomics, Molecular and Genetic
diagnostics, and Prognostics, cellular
biological APIs, therapeutic devices
(Merisis Therapeutics). It is also
creating other personalized products in
cancer, nephrology, podiatry, DFUs,
burns, sports injuries, orthopedics,
dermatology, etc.
“We are a bio-intelligent solutions
company with a focus on unique
formulations and solutions. All our
health care products are derived out of
in house R&D using data mining, lab
tests, artificial intelligence
applications, and advanced
biotechnology. We strive to be faster,
better and cheaper from any other
products and services company,”
concludes Dr. Kaushik.
The
Most
Innovative
Bio TechSolution Providers to Watch
in 2019
1
ACCUREX
BIOMEDICAL
he world of In Vitro
TDiagnostic Device (IVD) is
taking the centre stage with
existing and budding players
disrupting and creating their own
pathway. Contributing to this journey
is Accurex Biomedical Pvt. Ltd.
(ABPL) that is unlocking countless
opportunities for the betterment of
the masses by offering novel medical
diagnostic solutions. The below
excerpt is an exclusive interview
with team ABPL showcasing their
distinctiveness and curated acumen
which helps them in being ahead of
others.
IS: Share some insights about your
company, its inception story and
the vision behind.
Team ABPL: In 1984 almost 100%
of the diagnostic reagents were
imported into India. Mr A.J. Thakur
founded Accurex in 1984 to
indigenise the manufacturing of
imported reagents in India.
Accurex was the first company in
India to manufacture urine test strips
and enzymatic clinical chemistry
reagents in India. This was the
beginning of the IVD clinical
chemistry reagents manufacturing
industry of India.
The journey of Accurex since 1984
has been on a growth trajectory. With
the continuous launch of innovative
products, Accurex has created a
brand name in the Indian IVD
Industry.
IS: What your products & services'
ambit hold?
Team ABPL: In the laboratory
diagnostics space Accurex offers the
entire range of clinical chemistry and
haematology reagents. In
Instruments, we offer
semi-automated, fully automated
clinical chemistry, 3 part and 5 part
haematology analysers. We also offer
urinalysis test strips, urinalysis
meters and immunology rapid tests.
In the Point Of Care (POC) segment
we offer blood glucose meters,
haemoglobin meters, HbA1c meters,
immunofluorescence meters, uric
acid meters and respective test strips.
IS: With regards to your
organization’s profound industry
experience, how do you think the
diagnostic industry and market
have evolved and what can be
expected in the forthcoming years?
Team ABPL: The diagnostics
industry is getting disrupted by point
of care (POC) testing. Point-of-care
testing (POCT), or bedside testing is
defined as medical diagnostic testing
at or near the point of care—that is,
at the time and place of patient care.
This contrasts with the historical
pattern in which testing was wholly
or mostly confined to the medical
laboratory, which entailed sending
off specimens away from the point of
care and then waiting hours or days
to learn the results, during which
time care must continue without the
desired information. POC testing is
getting popular in the medical
diagnostic industry. Through POC
testing the lab tests are available at
the doctors and patients at home.
This is convenient for the patient.
Accurex has launched a complete
range of POC products to ensure
faster and convenient testing.
IS: What are the benefits gained by
your clients/users from your
products/solutions/services?
Team ABPL: Diagnostics affects
70% of medical decision and in only
3% of the healthcare costs. There is a
dire need in India to reduce the ever-
increasing cost of health care and
diagnostics plays a pivotal role in the
efficient use of resources.
TESTING LIFE AND SAVING LIVES
January 2020|14
Mr. Abhinav Thakur
Managing Director
January 2020| 15
India is till date dependent on
imports for its IVD needs with
almost 80% of IVDs are being
imported. The cost of manufacturing
in the developed world is many times
higher than the cost of manufacturing
in India consequently by
manufacturing indigenous products
Accurex lowers the healthcare costs
in India.
By using preventive diagnostics
effectively we can prevent diseases in
advance and significantly lower the
cost of health care in India.
Its an honour for Accurex to
contribute to the reduction of
healthcare cost to patients and
ultimately to our country.
IS: Tell us about Mr Abhinav and
his contribution to the company
and its success.
Team ABPL: Mr Abhinav Thakur
was studying in the USA when,
unfortunately, his father passed away
prematurely. He came back to India
to run the company for his family. At
that point of time the motivation for
him was survival of the family
business.
Now the motivation for him is to
grow the company so he can have an
impact on the healthcare industry by
manufacturing affordable and high-
quality medical diagnostic products.
Since his appointment as Managing
Director, APPL has grown 4.2 times
in revenue and our team size has
increased from 90 to 170 individuals.
We have moved from a diagnostic
reagent company to diagnostics
reagents and instruments company.
IS: In what ways does your
organization contribute towards
the Corporate Social
Responsibility cause?
Team ABPL: We at Accurex believe
wealth creation leads to wealth
distribution. So, it’s our endeavour to
create prosperity so we can
contribute towards the economic
development of India.
IS: What obstacles and/or
limitation does your organization
face while growing, sustaining or
retaining its clientele?
Team ABPL: The diagnostics
industry is capital intensive because
the business model in our industry is
moving towards analysers being
placed on reagent rentals. To place
analysers on reagent rental we need a
large capital investment. This is the
challenge we face in our industry.
IS: Could you list out the most
growth-deteriorating challenges
for your organization till date?
Team ABPL: Service is key in the
diagnostics industry. The analysers
need a fast turn around time (TAT) in
case of breakdown. Providing service
in a large geographical country like
India with underdeveloped
infrastructure is a challenge.
IS: What does the future hold for
your organization in terms of
internal as well as holistic
development?
Team ABPL: Now the motivation
for Mr Abhinav is to grow the
company so he can have an impact
on the economic development of our
country. He strongly believes that
economic development is the
antidote of poverty.
The next major milestone for him in
this decade will be getting Accurex
listed on the stock exchange.
IS: Would you like to highlight any
awards, accolades or testimonials
your company has achieved
throughout?
Team ABPL: Over the years we
have achieved various awards and
recognitions such as
• Ranked #10 in BioSpectrum Top
20 Indigenous Medical Devices &
Diagnostics Companies 2019
Survey
• Selected as “Visionary leader in
Healthcare 2017” by Medgate
Magazine
• Ranked at number 19 BIOTECH
companies ranking by Biospectrum
Magazine analysis done by KPMG
• Altina Entrepreneurs Excellence
Award,2017 in the healthcare
category
• India’s most Innovative and
Valuable Medical Devices
Company 2017
Interview With Insights Success
January 2020|16
While everyone speaks
about how innovations
are changing the face of
the world, few talk about the research
that goes behind it. What we are
currently enjoying as the latest
technology or an innovative marvel,
might have actually taken years or
may be decades of research to
develop into its current form. As
such, it is crucial that research
companies, especially start-ups, be
given a conducive environment
where they can flourish to help
mankind.
Bangalore Bioinnovation Centre
(BBC) is one translational research
centre catering to the needs of
startups in the broad areas of Life
Sciences viz., Health Care
(MedTech/ Pharma/ Bio-Pharma),
Agriculture, Food/Nutrition,
Industrial Biotechnology and
Environmental Biotechnology. BBC
is an initiative of Department of IT,
BT and S&T, Government of
Karnataka with funding support from
Department of Biotechnology,
Government of India. The centre is
located in Bangalore Helix
Biotechnology Park at Electronic
city, and thrives between academic
institutions like Institute of
Biotechnology and Applied
Biotechnology (IBAB), Centre for
Human Genetics (CHG). The centre
started functioning since April 2015
and has currently 38 startups being
physically incubated and 7 graduated
companies. BBC is envisioned to
nurture bio-startups ecosystem and
catalyse it's growth to benefit the
society at large and contribute to
bio-economy. As a not for profit
company and relationship builder,
BBC supports quality programs and
trainings that ensure strategic and
progressive growth of innovation and
entrepreneurship in Life Science.
Recently BBC received the Award
for being finalist in National
Entrepreneurship Award National
Centre for Excellence conferred by
Chief Secretary to the Government of
Karnataka, Shri Vijay Bhaskar T M,
IAS
Nurturing Start-ups
Bangalore Bioinnovation Centre
provide services such as
Infrastructure/ Equipments,
networking, branding, funding and
mentoring to startups in the field of
Healthcare, Agriculture,
Food/Nutrition, Industrial
Biotechnology and Environmental
Biotechnology. These startups utilize
the facilities to conduct R&D and
translate them into products. Many of
the incubatees have commercialised
their products based on technologies
like Artificial Intelligence for
diagnostic purpose, Point of care
devices, Non- invasive testing
devices, Customisable 3D printer, 3D
printed skin, kits for diagnosis and
Prosthetic foot. Some of the startups
involved in developing breakthrough
products are as detailed below.
OmiX Labs(OmiX) developed “The
OmiX Technology Platform”
designed to look at gene signatures
for Antimicrobial resistance. They
are also providing services pertaining
to unitized room-temperature stable
kits and automated assay setup.
Pandorum Technologies Private
Limited (PTPL) is engaged in
development of Bio-Engineered
Human Cornea that can be used as
Platform for in vitro toxicology and
safety assessment and Lab Grown
Mini Liver that can be used as
Platform for pre-clinical drug
discovery and development.
Innov4sight Health and Biomedical
Systems Private Ltd. is working on a
Bangalore
Bioinnovation
CentreHelping Innovative Ideas Hatch
January 2020|18
device to simulate fertility factors
called “FERTIMULATOR”. They are
also conducting research on
Biologically Activated Peptide
Concentrate (BAPC) used for
fertility factors regeneration.
Next Big Innovations Lab (NBIL) a
startup involved in development of
Innoskin®, a 3D Bioprinted Human
Skin and “TRIVIMA”, NBIL’s 3D
Bioprinter. These are innovative
breakthrough products that have
gained recognition and award from
established companies like Merck
from Germany.
Enriching Mankind
The incubatees, both current and
graduated, over time have developed
products that are now helping
companies and end-customers in
several ways. Here are some
products that are making a marked
difference:
Innov4sight Health and Biomedical
Systems Private Ltd. came up with
two technologies in the field of
fertility treatment. One is
FERTIMULATOR, a simulator
machine and one of the prime
products of Innov4Sight which is
covering simulation for fertility
specialists and embryologists to
simulate Oocyte Retrieval (OR),
Intra-Cytoplasmic Sperm Injection
(ICSI), and In Vitro Fertilization-
Embryo Transfer (IVF-ET). The
newer version of FERTIMULATOR
is incorporated with Regenerative
Medicine (RM) services that is
intended to help IVF experts in
treating endometrial deficiency, one
of the key factors causing infertility.
Next is the BAPC as mentioned
earlier, which is used for endometrial
regeneration. The future prospects of
this medicine is treatment of
infertility in women to induce
ovarian regeneration and oocyte
production.
OmiX’s portfolio of products and
services aim to create impact on
millions of lives. They offer a
“Insights
Put Into
Action”
Dr Jitendra Kumar
Managing Director
The
Most
Innovative
Bio TechSolution Providers to Watch
in 2019
1
January 2020| 19
platform for early detection and more accurate
identification of organisms causing infections. At the
same time, they are also determining whether the
infection is potentially drug resistant. OmiX Labs can
conduct drug resistant tests in only three hours, whereas
conventional tests require a minimum of three days in
laboratories equipped with microbiology facilities.
PTPL’s two breakthrough technologies include
Bio-inspired Corneal ‘ink’ that can be used as ‘Liquid
Cornea’ for therapeutic application and to ‘print’ Corneal
lenticule for human implantation for treating visual
impairment due to corneal defect. This has a social
impact as this will restore the sight of many people with
corneal defect. The other invention is mini liver platform
(normal and diseased models) which will be used in
pre-clinical drug screening (discovery and development)
by the pharmaceutical industries/CRO’s. This model will
significantly reduce the cost and time of new drug
discovery resulting in affordable drugs available to the
patients.
NBIL has focussed their research on finding alternative
for testing of products on animals, which is currently
banned and restricted. The current gold standard testing
alternative, 3D cultured skin, is priced extremely high
and has inconsistency from batch to batch. This has
motivated the startup to develop Innoskin®, an
economical and consistent product. Added to their
portfolio is NBIL's patented 3D Bioprinting technology
which allows positioning of cells with micron level
precision, thereby enhancing cell-to-cell interaction
within the tissue construct and reducing the chances of
batch-wise inconsistency.
An Experienced Motivator
Dr Jitendra Kumar, Managing Director, holds a PhD
in Biotechnology from Institute of Microbial
Technology, Chandigarh, a prestigious national
laboratory affiliated to Jawahar Lal Nehru University,
New Delhi. Subsequently, he moved to University of
Illinois at Chicago, where he worked on Leukemia. In
the next stint as a Post Doc at Ohio State University,
Columbus OHIO (USA) he worked on various cutting
edge research projects. He is the author on several
internationally acclaimed peer reviewed papers. He holds
an MBA degree from prestigious Fisher College of
Business at Ohio State University. After returning from
US, he joined as a Vice- President of Life Science
Incubator at IKP Knowledge Park, Hyderabad where he
was involved in actively mentoring Incubatee companies
and creating pipeline of entrepreneurs through
innovative models of team building around the
technologies. As the Director & Head of BBC his current
focus is on Incubating Innovations is Agriculture, Food
and Nutrition, Biofuel/Bio-energy and
Pharma/Healthcare. He is working closely with
Karnataka Biotechnology and Information Technology
Services (KBITS), Department of IT, BT and S&T, Govt
of Karnataka, to create a vibrant Life Sciences
Innovation cluster in Bangalore.
Helping Start-ups Grow
The startups at BBC are focussed primarily on delivering
solutions to problems prevailing in the biotech market.
The areas of research bridges the gap in technologies and
hence offer competitive products to meet the demands of
the market. This approach has fetched the startups
competency in market. The key impediment for the start-
ups to grow is the non-availability of funding. BBC
facilitates government funding called “SEED FUND” for
development of innovative ideas, incubation,
entrepreneurship thereby creating a bio-cluster working
in synergy with ecosystem partners like other similar-
minded startups, SMEs, industry, investors, government
organizations, policy think tanks and business
organizations. This paves opportunities for networking to
progress in their research and development. However,
the main challenge faced by these startups during
translation of research into products in market is the
requirement of substantial investment. This stymie the
growth and vision of startups and many fall into the
“valley of death”.
Positive Vibes for the Future
BBC is mandated to nurture start-ups working in the
broad areas of Life sciences with an aim to improve the
quality, efficacy and sustainability of healthcare,
agriculture, industrial & environmental biotechnology
products. A holistic development can be achieved only
when diversity and inclusivity is embedded in startups
from the beginning to bring out inter-disciplinary
innovations. BBC is fostering such a holistic growth
among the startups through interaction and learning and
for the greater benefit of society.
January 2020|20
SocialMedia
Marketing
he absence of pharma brands on social media creates a significant void of reputable healthcare information to aid
Tpatients,” writes Dawn Lacallade, LiveWorld’s Chief Social Strategist.
Social media infiltrate virtually every facet of an individual’s digital life. Today, patients are using social media as a major
source of information and healthcare research. Thus, it is essential that pharma companies should be present on social media
to provide full and accurate information to the consumers. To comprehend how social media can assist patients, it is crucial
to understand what compels people to use social media as a source of information.
Social media allows interaction among people which involves exchange and creation of information. It is the perfect conduit
for pharmaceutical companies to connect with their customers, patients and physicians.
According to the current FDA regulations, pharma companies are not able to easily join in a conversation to provide accurate
and balanced information. Regulations dictate that, in a single social post, brands are required to provide precise facts on the
benefits and hazards associated with conditions and products. Due to the character limitations on many social media
platforms, most pharma companies prefer to stay out of the conversation. This results in circulation of falsified information.
This information can be either marginally inaccurate or significantly harmful.
“
for
Market Dashboard
January 2020|22
Although the communication of pharmaceutical industries is highly
regulated, they are gradually adopting social media platforms to reach and
interact with consumers and healthcare professionals. Here are some of the
top social media practices to look out for:
Crafting Customer Experience
Several marketers think that their job is finished once the sales team
takes over, but in reality, it is just the beginning. The way people
experience your brand will impact the way they think about you, which
will have an enormous effect on the success of your company in the long
run. Devoting a part of the marketing budget to nurture the
existing clientele will make their experience splendid and
thus promote brand loyalty. It is also crucial to respond
whenever your brand in mentioned publicly, whether
positively or negatively, which will help cultivate a
strong and lasting relationship with your customers.
Younger generations are increasingly withdrawing
from traditional social media platforms and adopting
more innovative channels that are more intimate in the
way of communication. To keep up with this challenge,
companies need to find a way to automate the process
wherever possible.
Regulating Content
Pharma companies need to develop content marketing strategies that merge each
piece of content on every channel with their organization’s objectives and
customers’ needs. Creators need to have a clear business objective including the
value that will be delivered to distinct audiences. All companies need to have a
social media compliance officer who will work closely with a corporate legal
counsel and develop a complete strategy and decide if there will be consolidated
social media posting or if individual employees will have the consent to
participate. And lastly, it is critical that all employees understand their role in
corporate social media and be trained on the rules.
Overall Integration
Pharma companies should stop thinking about content marketing and social media
as add-ons. To boost their outcome for clients, content and social marketing need to
be a part of almost every program. To develop a fully integrated program, companies need
to involve influencers and content marketers during the initial stages. Implementing an
organized approach to content and moderation will not only optimize the processes, but also aid
in assuring authorities that all the bases are covered to protect and provide value for the brand.
Investing in Employees
An independent survey discovered that 72% of social media users expect response within an
hour from the brands they follow. This has caused brands to start heavily investing in cross-
functional social media teams that can keep up with the increasing number of client pings
January 2020| 23
every day. Encouraging and incentivizing team members to share brand messages on their own social media accounts, is
predicted to be a game-changer in the coming days. However this cannot be forced, it is essential for employees to want to
share company posts, and along with this the content has to resonate with their own audiences.
Influencer Marketing
Influencer marketing will continue to develop and become an even more established part of the strategy. Currently many
brands try influencer marketing and fail as it is not easy to find effective influencers. Additional data will help in selection
of the right influencers and analyze the results from influencer campaigns. Today, in healthcare, influencers are often
regular people. Some are directly affected by a disease or are being treated with a specific product, while others have
gained a lot of knowledge about a condition and are considered as Subject Matter Experts. The common trend is to select
someone who has an ever-increasing community of followers who value their opinion.
Numerous companies still think of social media as merely a marketing tool which is not true anymore. Consumers learn
about products on different social networks and seek customer service on messaging channels. Moreover, good storytelling
has always been an essential part of effective marketing. But social media is changing the way audiences consume stories
and pharma companies will be required to keep up with the evolution of social storytelling if they want to remain relevant.
Yet there is still a note of caution with compliance being the foremost priority of pharmaceutical companies. But as
industries are starting to adopt social media without clear regulatory guidance, remaining compliant will be the main
challenge to face.
BUSINESS
MARKETING
January 2020|24
Dr Ritu Hinduja is an MD,
MRM (UK), and DRM
(Germany) who has
completed her Fellowship
in Reproductive Medicine
(India, Spain, Israel). She is
a certified Genetic
Counsellor and a well-
known medical
practitioner. Dr Ritu
specializes in Reproductive
medicine and Infertility
treatment and has an
experience of more than a
decade for the same. For
her dedication and
contribution, she has been
honoured with various
prominent awards like
FOGSI Chorion Award for
Best Research, FOGSI-
Kumud Tamaskar Award
for Best Research in
Infertility, and FOGSI-
Dr Shanti Yadav Award for
Infertility, to name a few.
Insights to Choosing
the Right IVF Center
About The Author
Dr Ritu Hinduja
Senior Consultant –
Reproductive Medicine,
Nova IVF, Andheri (Mumbai)
January 2020|26
Reproductive medicine is an
ever advancing field of
medicine which provides a ray
hope for couples who are battling
infertility.
IVF is usually effective, though not
always immediately for all women,
research suggests that if you’re
considering assisted reproductive
technologies to help you conceive, it is
suggested that you chose your fertility
clinic well and that can improve your
odds of a good outcome. But with so
many clinics out there to choose from
deciding which one best meets your
needs can feel a bit overwhelming. You
can use the following pointers to help
you chose a clinic that meets your
needs.
Do Some Research
All fertility clinic may apparently look
the same, but they are not, and it does
not hurt to do your homework. You
may want to consider enquiring about
the success rate of the clinic. While
enquiring about the success rates it is
advisable to compare oranges to
oranges so compare the success rates
for your age group and also the kind of
treatment that you plan to do. Once
you are convinced about the success
rates it's a good idea to have a look at
their accreditations you can either look
for ISO, ISAR or a NABH
accreditation in the Indian
subcontinent. Also make sure that the
clinic is registered with the ICMR
(Indian Council of Medical Research)
Ask Questions
Before you commit to an IVF clinic its
always best to ask all the questions that
come to mind even if you think they
are silly. It’s your treatment and you
need to be at peace at what you are
proceeding with and it’s your right to
know every pro and con about the
treatment or any other query that may
come to mind. Some of the questions
you may consider asking:
• The process of IVF per se
• How many embryos do they
transfer?
• What is their embryo freezing
program like? What is their contract
time period? What will be renewal
clause be?
• Do they prefer a day 3 or a day 5
transfer?
• The technique of fertilization ---
ICSI for all or IVF for selected
cases?
• Do they have an identification
system in place for the Gametes?
• How are donors screened and
allotted?
• Will you need genetic screening?
• Will you need sperm selection
techniques?
• What will happen when you get
pregnant? who will you follow up
with?
• What will happen if you don’t get
pregnant?
• If attempting genetic screening – you
may want to ask which lab they are
associated with for the analysis?
• Do they have an in house full time
andrologist and embryologist?
• Is it an all under one roof facility?
Find out if they have a Psychological
Counsellor or a Patient-support
Group
It's important for a fertility clinic to
offer indicated medical treatment to
help you conceive but it’s also
important that there is enough
emotional support available while you
are embarking on one of the most
emotional journeys of your life. Also,
if the sessions with the psychologist
are chargeable or are free of cost.
Consider the Monitory Factors
Always take your financial counselling
in written from the clinic. Consider
have they given you all the inclusion
and exclusion criterion’s in written.
The inclusion criteria you may want to
look for are gonadotropins, blastocyst
transfer and luteal support medicine till
Bhcg. Always gauge how transparent
they are attempting to be in their
pricing.
Trust your Instincts
When you’re considering a fertility
clinic, always trust your gut feeling. I
think patients’ gut feelings are usually
pretty good. Life’s most precious
commodities are your gametes and
hence any decision you take regarding
them has to be carefully contemplated
hence it is important that you get a feel
of the people who are going to be
handling your gametes. Consider the
professionalism of the staff of the
clinic and how they treat you , pay
attention to what they say to you and
how professional and genuine does
their care feel to you and does their
care make you feel comfortable and at
ease or do you feel rushed or ignored.
If Applicable to you may want to
find out more about the Special
Program the Center has
• Who is the andrologist attached with
the center if you are going to need
testicular sperm extraction?
• If you are looking for social fertility
preservation: then you may want to
know about their oocyte freezing
facilities. Find out how many times
you may need to do egg retrievals to
freeze the optimal number of
oocytes. What is the payment
structure? How long will the oocytes
be cryopreserved according to the
initial contract; how will the renewal
clauses be.
• Fertility preservation program for
cancer patients.
Even after all the above pointers only
you can know which clinic suits you
best and always remember A great
fertility clinic isn’t just one that can
give you effective treatment, it is the
one with staff that is compassionate,
has transparent and clear financial
counselling, smooth administrative
processes and a system in place for
exceptional emotional support.
January 2020| 27
Experts Opinion
The Indian Biochemical sector is initiating
breakthrough enactments and is laying the
foundation of a stronger growth trajectory. With
this immense growth potential, the sector will continue to
play a pivotal role as an innovative manufacturing hub and
unlock countless opportunities for today and tomorrow.
Acknowledging this scenario, organized manufactures are
offering exclusive solutions for the betterment of the
economy alongside delivering quality to the core.
Founded in 1975, Sisco Research Laboratories Pvt. Ltd.
(SRL) is one such organization that stands amongst the
oldest and most respected manufacturers of specialty fine
chemicals, microbiological, nanotechnology and
biotechnology reagents. It's an ISO 9001-2015, CGMP,
FDA, and CE certified organization that employs about 300
personnel to manufacture. Headquartered in Mumbai, SRL
effectively services the needs of scientists, researchers,
quality control managers of industries, researchers of
institutions and academic bodies.
Today, the company stands amongst the five leading
Reagents and Biochemicals providing companies in India.
It's patronized by various National Laboratories, CSIR,
ICMR, ICAR, DRDO, IITs, NITs, NISER institutes and
National Universities thereby, leading to accreditation and
acceptance by the multinationals, Indian manufacturers and
even overseas buyers.
Apart from all this, SRL also makes its modest
contributions towards various CSR activities.
The Success Story
Mr S. K. Agarwal laid the foundation of SRL way back in
1975 when India's premier Research institutes and
academic bodies such as Universities and Colleges were
Sisco Research
Laboratories:A Name Synonymous to Quality Reagents and Biochemicals
relying wholly on imported reagents and chemicals. Being
the Managing Director, his sole aim was and is to
contribute to this ever-increasing ocean of scientific
research and learning in the country.
At that point in time, he faced a plethora of challenges
concerning designing, production & testing methodologies,
capital, operations, and staff training. Making staff
understand the importance of high-quality testing and
manufacturing standards was not an easy task for the
company. Also, customers preferred to import chemicals
from the leading companies in the world rather than
embracing Indian products.
Keeping up with times and acknowledging these trends, Mr
Agarwal embarked on a journey of manufacturing
speciality chemicals and reagents at par international
quality in India. With the passage of time, his curated
acumen and consistent efforts successfully carved out
affordable pricing strategies that have the potential to
satisfy the needs of the customers with limited financial
grants.
Currently, his leadership is helping the company in
contributing to the growth of scientific research in India.
The young dynamic Directors - Mr. Akash Agarwal and Mr.
Vikas Agarwal (Grandsons of Mr. S.K. Agarwal) have taken
the SRL's visions and goals to a broader and higher
mission. Their education, experience and leadership is
enabling the company to penetrate many new markets
(Pharma, FMCG, Cosmetics & R&D etc.) and reaching to
every corner of the world. They are also upgrading and up-
scaling the product range of the company by introducing
newer reagents in the field of diagnostics, nano-technology,
molecular biology and PCR related reagents.
January 2020|28
Meet the Cornerstones
Mr Ramesh Agarwal, Director and son of Mr Agarwal is
associated with the company since last four decades and has
been especially credited with the procurement of raw
materials for the company with his business acumen in bulk
chemical industry.
Mr Akash Agarwal and Mr Vikas Agarwal, the young
Directors of the family-owned company have introduced
many verticals of management at the head office. While Mr
Akash has completed his Chemical Engineering and MBA
from USA, Mr Vikas has done his Post Graduation in
Commerce and MBA from UK. They have been driving
digitalization and computerization in operations at all levels
for faster growth within India and overseas.
A biochemist devoted to R&D, Late Dr M. R. Raikar
pioneered the development of various reagents under the
leadership and guidance of Mr Agarwal. His knowledge and
experience assisted the company in launching its first
manufacturing unit in Kashimira in Mumbai.
A Reader in Mumbai University and a devoted student of
Organic Chemistry, Late Dr Pandit had been instrumental
in establishing the second manufacturing unit in MIDC,
Turbhe, Navi Mumbai.
The Corporate R&D and Production Manager of the
company who stands amongst the proficient R&D
scientists having experience in UK, US, and MNC pharma
companies has led the team of chemists at Turbhe factory to
effectively synthesize highly purified reagents, phase
transfer catalysts, and specialized solvents thereby adding
to the growth of the company.
The Corporate Quality Control Manager of the
company who heads the quality control department at the
MIDC, Taloja factory has been accredited with the
development and modifications of analytical methods of
hundreds of biochemicals, reagents, and solvents.
A versatile manufacturing microbiologist, who Heads the
Microbiology Division of the company is helpful in
The
Most
Innovative
Bio TechSolution Providers to Watch
in 2019
1
We ensure that the
products we manufacture
give the desired consistent
results batch-after-batch
“The Company vision is “
to serve the endless process
of science
‘‘ ‘‘
Mr Akash Agarwal
Director
Mr Vikas Agarwal
Director
January 2020| 29
developing a new production department of dehydrated culture media,
playing a pivotal role in catering to health care, environmental, and
microbiological quality control.
The Chief Accountant has been aptly instrumental in handling the
financial and accounting management of the company.
The Regulatory Personnel has been instrumental in introducing
several regulatory systems like ISO, CE, GMP, and VQs to meet the
industry’s and government’s mandatory requirements.
Rewards & Recognitions
Mr S.K. Agarwal was awarded the ‘Indian Achievers Award' in 2014
for Industry Development in the field of CSR and Sustainable
Development.
A renowned media company Bio Spectrum recognized SRL amongst
the ‘20 Top Biotechnology Companies’. It had also published a profile
of Mr Agarwal, as a leader in the field of biotechnology-related
reagents in the country in the year 2013.
In 2010, he was felicitated by ISGF / AISG in recognition of his
contribution to Scout and Guide Fellowship during the past 50 years
in India. He was also a member of the ISGF World Committee from
1993 to 1999.
He has attended & successfully completed MIT Management
Executive Education (Leading Organisations and Change) in 2018
from EMERITUS institute of management, US.
Outperforming Own Milestones
SRL manufactures and provides more than 6000 products across
15000 Stock Keeping Units (SKU’s). Its product menu includes
Organic & Inorganic reagents, Biochemistry and Molecular Biology
reagents, Nanotechnology products, Microbiology dehydrated culture
media and PCR reagents.
The company’s products are quenching the needs of various industries
like Pharma, FMCG, Cosmetics, etc. Companies embrace these
products for their R&D and pilot-scale & bulk production. However,
the introduction of newer range of diagnostic reagents has created a
shift in the buyers’ preference for SRL products alongside gaining the
advantage of economical prices and promoting availability.
With the expansion of its export business in the Indian subcontinent,
Far-east, Europe and the US, SRL is all set to observe growth rates in
excess of 30%-40% on year-to-year in the next 5 years.
Explore more on srlchem.com
Mr S. K. Agarwal
MD
Mr Ramesh Agarwal
Director
January 2020|30
Biobanking is going to be the
new world order to provide
first-in-class transformative
medicine replacing hospitals and based
medical, healthcare institutions. As far
as the bio-samples are considered,
storing for applications will evolve to
become a blue-chip industry. Biobank
derivatives put to applications are
forecast to be pegged at 500 billion
global market opportunity covering big
data in genomics, drug discovery,
development, CAR-T cell therapies,
transplantations, repair, and
regeneration.
Transcell Biolife was founded to be a
biobank for the intended applications;
built on preservation theme and
technology translated to apply.
In Biolife’s context with credible in-
house R&D, Intellectual property
surrounding the story as translating the
prowess of adult stem cell technologies
to the intended applications,
thebiosamples derived stem cell units
and data are invaluable assets in the
repository. The belief and the
conviction have been handling the
right kind of bio-samples, derived
cellular platforms depending on the
use, with Biolife’s team emerging as
revenants in the wake of industry
transformation, adaptation.
With a track record of offering bio
storage products and related services,
Biolife today has positioned itself
addressing expectant families and
families with kids aged between 5 and
11- year markets. The vision of the
company is to become an epicenter
biobank for Asia facilitating
transformative medicine. Biolife is a
revelation from India in the field of
biobanking with applications shown
beyond autologous presentations.
Extraordinary Services and
Products
ScellCare
ScellCare is into storing umbilical
cord, bone marrow and bio-sample
derivatives (cellular units and stem cell
transcriptomics). Collection is non-
invasive, painless, and poses no risk to
the donor, while source is being
categorized as biological discards. In
India, blood forming (hematopoietic)
stem cells from bone marrow or
umbilical (nadi) cord blood are
routinely used to treat blood cancers
and different blood disorders as
Standard Care in managing 40 different
kind of diseases. The stem cell
transcriptomics derived report is
predictive (not diagnostic) in nature
with details on the donor stem cells
genomics in readable format. This is
completely next generation feature of
the biobanking service that Biolife has
integrated into it’s regular offering.
ToothScell
Dental stem cells are adult stem cells
found in wisdom teeth and baby teeth.
They are being studied for applications
in regenerative medicine and dentistry
while over 2000 clinical trials are
ongoing at global level. ToothScell
program acquires donor’s tooth stem
cell nucleotide sequence before
cryopreserving the units in the
repository. Identification of disease
genes from the sequence can have
applications in proactive healthcare
approach and predictive testing.
Relationship of dental stem cell
molecular markers with other systemic
illnesses like that of heart ailments,
diabetes, immune disorders are known.
ToothScell is a comprehensive and
progressive relationship with it’s
clients offering precious service from
collected bio-sample.
Benefits for Clients
Insightful, Latest, Modern, Credible,
Transcell Biolife’s laboratory driven
original data converted to users’
precious experience in the form of
biobanking related solutions. Biolife
empowers them by offering these
solutions to act informed addressing
their family’s wholistic medical,
healthcare requirement.
The Leader with Vision
S Dravida, the Founder, and CEO is
a scientist by profession, practicing to
translate the group’s proprietary stem
cell platform technologies to
applications. With utmost dedication
and focus on delivering maximum with
minimum input philosophy, she has
orchestrated Biolife for preserving all
precious things to offer the intended
applications keeping stakeholder value
in mind. It is her vision, which is built
on the team’s strengths to become
Asia’s epicenter biobank playing a key
role in facilitating the derived
applications, that sets Biolife apart
from the rest of the players.
Transcell Biolife
The Next Generation Biobank with Global Outlook
January 2020|32
L Krishna is the head of Operations
with Biolife team. He has been the core
member with technical, and medical
background contributing to the success
of present operations. His alignment,
passion for the company’s mission and
vision translating to setting an example
with Biolife achieving operational
efficiency is a rare talent. He plays a
crucial role in bridging the facilities
and the field dynamics with
commitment.
Adopting Digital Disruptions
The company believes and practices
original research driving the business
offerings from Biolife and so has built
unique internal complex processes
customized connecting digitization.
Starting from the client enrolment, till
the promised service from the Biobank
is delivered, the entire operational
(technical and sales) process is wired
while handling privacy related matters
as per the rule of the country.
Overcoming the Challenges
“We operate from India and this
market is crowded with known
businesses, models, markets for
example cord blood banking which is
commoditized. So, it was difficult for us
to get practitioners, evangelists,
ambassadors, sales champions in the
beginning who could proactively be
our referral points promoting our story
that has unique differentiators with
proven track record”, S Dravida
recollects.
Further, she says, “To our honest
self and after facing the market
and the customers for the past 7
years continuously sharing our
ups and downs that are different
from the others, Biolife stands tall
today with great connection
established with needy market. The
discovered growth formula
addressing bio-sample storage
disruptively is the ground breaking
strategy breaking all the growth
deteriorating challenges in this
space.” The vision, operating team’s
adaptability, ability to connect with the
user (B2B or B2C) on Biolife’s
strengths, core capacities have set any
competition at bay in the market.
The Future Roadmap
“As far as Biolife’s internal growth in
India, it is planned to be organic by
strengthening facilities, adding
channel partners from North and
Eastern states to handle volumes while
thegrowth formula embraced by Biolife
positions the company as epicenter
biobank in Asia building assets in the
repository to apply”, S Dravida
expresses her view regarding the
future road map for the company.
Biolife operates with a purpose and
the fact that it has growing
clientele and collaborations in
India is a testimonial in its
language.
Meaningful
innovation
does not need
to be based
on outright
invention. Rather,
there is an
exhilarating
shortcut. It is
based on bold,
new combinations
of already existing
components that
simultaneously
unlock heightened
levels of consumer
value and reduce
costs.
-Gabor George Burt
S Dravida
Founder & CEO
The
Most
Innovative
Bio TechSolution Providers to Watch
in 2019
1
‘‘
‘‘
January 2020| 33
Biotechnology is a the exploration and development of various biological
processes to achieve mainly industrial and various other purposes
cultivation of the plants, and improvements through breeding programs.
The processes also employs artificial selection and hybridization which emphases
its functionality. At present, the modern usage also includes genetic engineering as
well as cell and tissue culture technologies.
In earlier days biotechnology process was initiated by farmers who developed
improved species of plants and animals by cross-fertilizing or cross-breeding. In recent
years, biotechnology has expanded its core functionality widely which now focuses on
sophistication, scope, and applicability.
A well-known and author and writer is vague and can be unsubstantial, for example,
Clayton Christensen share his views as, "There are other dimensions of biotechnology. If
you think of biotechnology like the Internet, it's not a category - it's an infrastructure that
can be deployed to sustain or disrupt. In healthcare, the most complex problems at the high
end have to be dealt with in a problem-solving mode by the best, most experienced
physicians you can find.”
Biotechnology is immensely contributing towards agriculture which enhances its
functionality to the next level. Agriculture aspects have extremely changed with
biotechnology functions and increase readability of the process.
What is Agriculture Biotechnology?
Agricultural Biotechnology is also known as Agritech. It is an area of agricultural
science involving the use of scientific tools and techniques. There are several
techniques used in agriculture biotechnology such as Genetic Engineering,
January 2020|34
Agri Tech
Protoplast Fusion: Protoplast fusion is
also known as Somatic fusion. It is a
type of genetic modification in plants by
which two distinct species of plants.
In this method, it includes joining
of cells or cell components to
transfer traits between species.
Transgenics: Transgenics is the method
which involves the insertion of one piece
of DNA into another organism's DNA. It
works in order to introduce a new gene
into the original organism. This addition of
genes into an organism's genetic material
creates a new variety with desired
qualities.
Impact of Agriculture Biotechnology on
Economy and Social Life
The technology used in agricultural
productivity improved its usability and
functionality with some major factors
such as combine harvesters,
chemical fertilizers, and the green
revolution. Like every technology,
agricultural biotechnology will
also have its major impact on
economic and social.
In agriculture, crops using biotechnologies
have improved its quality and also been
used safely with benefits. The technology
influences the whole process by the
reduction of pesticide use. At present
agricultural biotechnology, one of the
factors that influence the health and
welfare of the farmers and other citizens in
the developing world.
Influence of Agriculture Biotechnology
in the Future
The aim of agricultural biotechnology
is to present the functionality of the
applications used in agriculture
biotechnology. The applications
are eagerly awaited to increase
Molecular Markers, Molecular Diagnostics, Vaccines,
and tissue culture. And it also modifies the living
organisms like Plants, Animals, and Microorganisms.
In recent times, Crop biotechnology has been developed
its functionality in agriculture and is also one of the main
aspects of agriculture biotechnology. Its desired qualities
are exported from a particular species of Crop to an
entirely different species.
How is Agriculture Biotechnology Used?
Genetic Engineering: The term is derived from
scientific research provides information about how to
move genes from one organism to another. This is known
as genetic engineering (GE) or genetic modification
(GM). Genetic engineering includes the transfer of
useful characteristics by inserting DNA of Plants, animal
or microorganism from another organism to another.
Molecular Diagnostics: Molecular diagnostics
significantly detect genes or gene products that are very
precise and specific. Molecular diagnostics is the method
used in agriculture to more accurately diagnose
crop/livestock diseases.
Tissue Culture: Tissue culture is the process of
regeneration of plants from the disease-free plant. This
technique allows reproduction of disease-free planting
material for crops.
Unified Methods Used for Corp Modification
Traditional Breeding: Traditional breeding method has
been used for centuries to improve crop quality and
quantity. The crossbreeding describes the combination of
two compatible species to create a new variety with the
desired traits. The crossbreeding can be only utilized
within the same or closely related species.
Polyploidy: Polyploidy is the method describes which
can be induced to modify the number of chromosomes in
a crop in order to influence its fertility or size. Through
naturally or with the use of chemicals, the number of
chromosomes can change. The process results in the
fertility changes in modification within the crop.
January 2020| 35
the productivity of crops, primarily by reducing the costs
of production by decreasing the needs for inputs of
pesticides. The process is mostly used in crops grown in
temperate zones. The application of agricultural
biotechnology can improve the quality of life by
developing new strains of plants that give higher crops.
The crops can be grown in a wider range of
environments which give better rotations to conserve
natural resources. It also provides more nutritious
harvested products that keep much longer in storage and
transport, and continue low-cost food supplies to
consumers.
According to Crop Science, the company with credible
authority on the progress and future implications of
Agricultural biotechnology states that, “Farming is
evolving in the 21st century with the development and
use of biotechnology crops. Scientists and agronomists
work in the lab and greenhouse to come up with genes
that improve crop yield and make corn, soybean, cotton
and canola plants more resistant to insects and more
tolerant to herbicides, drought, and stress.”
The biotechnology and its process is the evidence of the
contributions towards rural development around the
world. It serves as the source of inspiration for emerging
nations to complement existing practices with
agricultural biotechnology.
January 2020|36
Today, as technology is making
advancements, the world is
also progressing with an
exponential rate. This advancement has
also taken the healthcare space to a
different dimension. Yet, there are
many diseases and disorders that are
untouched by emerging technological
advancements.
Currently, it is estimated that
approximately 2.3 million people are
living with cancer in India.
Approximately 12 lakh new patients
get registered per year and 8 lakh
deaths occurs in a year.
While there are many brilliant minds in
the world working towards changing
the devastating scenario of current
cancer care, very few have been
successful in implementing it. One
such visionary startup FastSense
Diagnostics (FSD) has taken the
responsibility to bring the change
which the world is looking forward to.
The company is led by three dynamic
personalities. Dr. Preeti Nigam Joshi
is the Founder of FastSense
Diagnostics. While Harish Joshi and
Dr. Saildendra Mishra are the
Co-founders of the company. The
reason behind the genesis of FastSense
was when Preeti’s mother was
diagnosed with pancreatic cancer.
Growing with the Company’s Vision
It is known that most of the times lives
are lost to late diagnosis of diseases
when no treatment is possible. At
FastSense Diagnostics the primary
focus is to develop portable, easy to
use, early-stage detection devices and
models for complex diseases. It
focuses specifically on deep tissue
cancers and neonatal sepsis as these are
the untouched segments but deeply
affecting many lives.
Dr. Preeti says, “Our company is
driven by the vision of affordable
healthcare for all and the ability to
develop the indigenous technologies to
bring the cost down and take the
benefits of scientific advancements to
the last man in society.”
Revolutionary Products
FastSense is targeting to build point of
care devices for early detection of fatal
diseases, drug delivery systems for
deep tissue cancers and AI-based
modules for disease prediction. The
company majorly focuses on complex
diseases segment including cancers
(liver, pancreatic, GI tract, oral, lung),
neonatal sepsis, Alzheimer’s, etc.
Their premium product L-Sens which
would be hitting the market soon is a
handy device for diagnosis liver cancer
(Hepatocellular Carcinoma). The
advantage of the system is that it can
be used to screen a large population
prone to liver cancer.
The next product in the line is Sepsis-S
for neonatal sepsis. According to
Preeti, in an estimate, India alone
reported sepsis cases in
17,000/1,00,000 live births and that
data itself shows the gravity of the
situation. These cases are
comparatively high in the rural parts of
the country.
“Currently, there is no portable
detection method available to identify
the cases timely and we are filling the
gap by our kit “Sepsis-S”. It’s a state-
of-the-art minimally invasive device to
identify sepsis onset within 72 hrs. Our
products are compatible with
smartphones so data can be easily
transferred to doctors and healthcare
providers to get a timely assessment in
critical cases like sepsis,” expresses
Dr. Preeti.
Overcoming the Challenges
As a startup, there are many obstacles
that a company has to face. The
challenges increased when it came to
fundraising for FastSense. Being a
non-IT startup, all these obstacles
seemed more challenging.
Nevertheless, the company, through its
innovative thinking and goodwill,
received funding.
Dr. Preeti mentions, “The biggest
problem with technology start-ups (in
non-IT domains especially in health
tech) is fundraising as many times the
product development takes a long time
from 3-10 years for medical devices to
come into the market and to sustain
FastSense Diagnostics
The Next-Gen Technology for Swift and E cient Care
January 2020|38
during such long duration is a big
challenge. Although government
policies are creating a positive
environment for start-ups still it’s a
long way to solve all problems that
startups face.”
Recently, FastSense has received the
Bio Ignition Grant and NIDHI Prayas
award by the Department of
Biotechnology – BIRAC, Government
of India. Apart from this, the company
made a special news appearance in
BioVoice under “Special Startup
Series: Affordable diagnostic kits for
early-stage cancer detection.
Creating a Mark on the Society
In the current times, it is necessary to
develop oneself while taking each
other along. Intermixing of different
fields of expertise has been proven
beneficial. Dr. Preeti herself has a
background in biotechnology but she
now works in the field of
nanotechnology.
Preeti mentions, “We believe the future
to be bright as our products have got
good responses among experts and
clinical validation are on and we are
confident of hitting the market at
earliest. We will continue to strive for
developing products that are in sync
with our vision of affordable
healthcare. We are developing different
in-house facilities and gradually
working on team building to bring
likeminded people under the umbrella
of FastSense so that we could sail full
throttle to bring new products and
technologies for all.”
In the forthcoming years, a
combination of numerous information
technology like AI, ML, 5G,
computing efficiency and chemical
sciences will help tackle problems
that were otherwise not easy to crack
to date. It will further be possible to
interlink telemedicine, remote
surgery, personalized or customized
treatment regime. This will
ultimately turn the tables around
as the medical healthcare will
become distinctly affordable.
The prime
motivation
we have is
" Detect early
Save lives" and
our products
will bridge the
gap between
diagnosis
and treatment
and provide
better survival
rates
‘‘
‘‘
Dr. Preeti Nigam Joshi
Founder
Mr. Harish Joshi
Co-founder
Sailendra Mishra
Co-founder
At FastSense, we
have I3 (Innovation,
Inspire & Integrity) as
a common set of
values and our team
works with full
dedication to solve
complex health
problems to
improve lives
‘‘
‘‘
The
Most
Innovative
Bio TechSolution Providers to Watch
in 2019
1
January 2020| 39
The 10 most innovative bio tech solution providers
The 10 most innovative bio tech solution providers
The 10 most innovative bio tech solution providers

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The 10 most innovative bio tech solution providers

  • 1. Transforming Treatments to Personalized Cure DiponEd Dr. Kaushik Deb Founder, CEO, Managing Director Volume01|Issue06|2020 T H E10MOST INNOVATIVE BIOTECHSOLUTION PROVIDERS TO WATCH IN 2020
  • 2.
  • 3.
  • 4. one are the days, when Bio GTech sector was embracing only traditional processes to fight the complexities of the disease. Today, the sector is moving beyond the 'one disease, one protein, one drug' paradigm by leveraging pipelines showcasing multiple new-age drug modalities. These modalities are an even mix of compound varieties of traditional protein-enabled molecules – enzymes, monoclonal antibodies, hormones, and fusion proteins over a rapidly transforming area of cell therapy and Antibody-drug Conjugates (ADCs). Currently, the Bio Tech Solution Providers are putting their best foot forward in gaining deep biological insights into tangled diseases. They are consistently endeavouring to surpass every challenge coming their way with sophisticated engineered drugs that have the potential to save millions of lives across the globe. The Bio Tech business professionals are all set to unlock new business opportunities alongside disrupt the healthcare world to stay on top of different regulatory requirements. Acknowledging the changing dynamics of the society and skyrocketing demands, they are rolling out patient-centric solutions and creating a platform of healthy lifestyles. Besides, it's the right combination of tech-based advancements and agile manufacturing techniques that are taking this sector to be at the helm of 'Progress’and ‘Innovation’. Recognizing such professionals that are revolutionizing the Bio Tech Solution Providers’ segment and keeping innovation on their radar by staying up-to-speed with the developments, we have come up with this special edition of “The 10 Most Innovative Bio Tech Solution Providers to Watch in 2020”. This issue has featured a handful of companies offering a diverse and engaging mix of commitment and distinctiveness. It will help you to walk through a list of experts embracing a The Changing Scenario of Bio Tech Editor Rahul Niraj
  • 5. EDITOR’s NOTE multi-disciplinary approach and covering a range of relevant issues in its sector. On the Cover of the issue is DiponEd – an innovative healthcare biotechnology R&D driven company. The company is outshining its competitors with its innovative solutions and redefining the Bio Tech segment. Apart from such an insightful cover story, we have also enlisted, Bangalore Bioinnovation Centre (BBC) is a translational research centre catering to the needs of startups in the broad areas of Life Sciences viz., Health Care (MedTech/ Pharma/ Bio-Pharma), Agriculture, Food/Nutrition, Industrial Biotechnology and Environmental Biotechnology, FastSense Diagnostics (FSD) has taken the responsibility to bring in ‘Change’ which the world is looking forward to, Sisco Research Laboratories Pvt. Ltd. (SRL) stands amongst the oldest and most respected manufacturers of specialty fine chemicals, microbiological, nanotechnology and biotechnology reagents, and Transcell Biolife was founded to be a biobank for the intended applications; built on preservation theme and technology translated to apply. Alongside companies like Catalysts Bio, Clonz Biotech, Cordlife India, Bioxgreen Technology Private Limited and Invitrosense (P) Ltd. have also been featured in the listing of this edition. While flipping the pages, take note not to miss out the exclusive interview with team Accurex Biomedical Pvt. Ltd. (ABPL). A CXO named ‘Insights to Choosing the Right IVF Center’ by Dr Ritu Hinduja, Senior Consultant – Reproductive Medicine, Nova IVF, Andheri (Mumbai) will make you go gaga. Turning some more pages will help you find articles masterly crafted out by our in-house Editors. These articles will help you understand the current market scenario of this industry. Looking at the emerging opportunities and the growing possibilities, this issue of ours will introduce you to a whole new world of novelty. So, enjoy the exciting read!
  • 6. DiponEd Transforming Treatments to Personalized Cure Accurex Biomedical Testing Life and Saving Lives Contents CoverStory 08 Articles Market Dashboard Social Media Marketing for Pharma Industry Agriculture Biotechnology: Revolutionizing Agriculture Process Globally Agri Tech 22 34 14
  • 7. Bangalore Bioinnovation Centre Helping Innovative Ideas Hatch FastSense Diagnostics The Next-Gen Technology for Swift and Efcient Care Transcell Biolife The Next Generation Biobank with Global Outlook Experts Opinion Insights to Choosing the Right IVF Center 18 38 28 Sisco Research Laboratories A Name Synonymous to Quality Reagents and Biochemicals 32 26
  • 8.
  • 9. SME-SMO Executive Uma Circulation Manager Tanaji Digital Marketing Manager Prashant Chevale Technical Specialist Amar Sawant Co-designer Mayur Koli Art & Picture Editor Shweta Ambilwade Art & Design Head Amol Kamble Associate Designer Poonam Mahajan Copyright © 2020 Insights Success Media and Technology Pvt. Ltd., All rights reserved. The content and images used in this magazine should not be reproduced or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior permission from Insights Success Media and Technology Pvt. Ltd. Reprint rights remain solely with Insights Success. Printed and Published by Insights Success Media and Technology Pvt. Ltd. Corporate Ofces: Insights Success Media Tech LLC 555 Metro Place North, Suite 100, Dublin, OH 43017, United States Phone - (614)-602-1754 Email: info@insightssuccess.com For Subscription: www.insightssuccess.com Insights Success Media and Technology Pvt. Ltd. Off. No. 22 & 510, Rainbow Plaza, Shivar Chowk, Pimple Saudagar, Pune, Maharashtra 411017 Phone - India: +91 7410079881/ 82/ 83/ 84/ 85 Email: info@insightssuccess.in For Subscription: www.insightssuccess.in sales@insightssuccess.com January, 2020 Follow us on : www.facebook.com/insightssuccess/ https://twitter.com/insightssuccess Cover Price : RS. 150/- Editor-in-Chief Pooja M. Bansal Managing Editor Shruti, Darshan, SnehaPublishing Control Team RNI NUMBER: MAHENG/2018/75953 Technical Head Pratiksha Patil Business Development Lead Ashwini Pahurkar Sr. Business Development Executive Snehalata Lad Rahul Niraj Business Development Manager Megha Mishra
  • 10. Dr. Kaushik Deb Founder | CEO | MD COVERSTORY
  • 11. Dipon dETRANSFORMING TREATMENTS TO PERSONALIZED CURE ealthcare in today’s time has Hbecome crucial in terms of accessibility and ease of facilitation. As new diseases are emerging from the nooks and corners of the world, the medical industry with all its dynamism needs to double down to counter such diseases in an effective and efficient manner. Moreover, to target the specific diseases while diminishing or eliminating its effects, the advent of precision medicine is moving from a niche to a widely accepted method for treatments. Also known as personalized medicine, it is moving closer to be precise, predictable and powerful healthcare “We help various companies through contract manufacturing of Biologicals at our Class 10,000 cleaning room facility”
  • 12. approach which can be customized for any individual patient. Even the world’s best doctors and scientists don’t completely comprehend the development of different diseases in people and their response to the respective treatments. The ‘one-size-fits-all’ approach to medicine has been implemented by lots of medical and healthcare providers which is based on broad population averages. The traditional practices often misses its mark as each person’s genetic makeup is quite different from other people. This very often, can affect the health of an individual in important ways. The growing understanding of genetics and genomics is enabling the doctors to provide better disease prevention, accurate diagnosis, safer drug prescriptions and effective treatments for many people. Personalized medicine is playing a vital role in tailoring healthcare to every person's unique genetic makeup. That is the promising idea behind precision/personalized medicine. This approach towards the healthcare services has revolutionized how the medical industry works and have facilitated results that are quintessential for individual patient’s overall development. DiponEd BioIntelligence is an organization working with such an approach in the Indian healthcare domain. It is an innovative healthcare biotechnology company driven by strong in-house R&D. It offers precision and personalized medicine products, services, and solutions meeting global standards. The company is developing a point of care biological devices for isolation of stem cells, PRP, Biologicals, Biosimilars, Neo Antigens, and Cellular therapies. These therapies include Mesenchymal Stem Cells, NK Cell & T cell for cancer, autoimmunity, diabetes, neurological problems, orthopedics, infertility, cardiovascular disease, diabetes, anti-aging, and dermatology, etc. “We focus on developing the next- generation bio-intelligent products to address unmet healthcare needs,” says the team of DiponEd. More about DiponEd DiponEd has also developed a range of personalized diagnostics and prognostic tests like liquid biopsies, gut metagenomics, pesticide tolerance, genetic predispositions, stress scoring, 3D printed orthotics- prosthetics - modeling, drug overloads, omics of diseases, etc. under its brand Merisis Therapeutics. DiponEd Institute of Regenerative Medicine has been offering education in regenerative medications to clinicians through its hybrid online and hands-on training programs. The company was started in 2010 with an idea to develop solutions and treatments for unmet medical needs like cancer, nonhealing wounds, burns, muscular dystrophies, autoimmune conditions like rheumatoid arthritis and T1 diabetes, and several other debilitating conditions like ALS, MS, COPD, ILD, T2 diabetes, etc. The team at DiponEd soon realized that prevention is better than cure for most of these above-mentioned conditions. Though, integration of preventive, “Theworldissittingonatimebombofpre-cancer andpre-l,ldiabeticpatients.Weneed tostartprogramsthatprovideAtoZsolutions”
  • 13. predictive, participatory, and personalized medicine is required to reach from ‘treatment to cure’. This could prove to be a major diversion for current health care treatment business models. “We then started working on developing products and services like predictive and prognostic genetic and molecular tests for suspects or patients, and also personalized therapeutics,” states DiponEd's team. The company is currently integrating many in-house technologies as well as some foreign service providers to make an entire ecosystem to develop a personalized cure for various diseases. DiponEd-CRS (Contract Research Services) is a wing of the company, providing an R&D ecosystem with a team of highly experienced and qualified scientists. The wing acts as a supporting facility for many international Bio-Pharma companies. This division offers its services in the domains of integrated drug discovery of small molecules in the areas of in- silico modeling, PK-PD modeling, and system biology. These services also facilitate ADME, toxicology, pre- clinical optimization, in vitro biology and (Enzyme assays, Cell-based assays, Ligand binding assays, GPCR, ELISA) in vivo biology, etc. DiponEd also provides services in the domain of Molecular biology, immunogenicity assays, formulation development and Regulatory Assistance for the Indian FDA. DiponEd CRS is an official empanelled partner to Andhra Pradesh Medical Tech Zone (AMTZ), Kalam Institute of Health Technology, for medical devices and regulatory support. Versatile Offerings, Simplified Services The power of biotechnology and biomedical engineering has helped the company’s R&D team to design multiple programs targeting cellular biologicals, stem cell transplantation & processing protocols, developing monoclonal antibodies (MAbs) and cellular therapies. “We design and create biomaterials using our proprietary 3D printing technology and 3D tissue engineering,” states the team of DiponEd. The company's focus is on current personalized medicine which includes genetic predispositions, mutation detection, cancer-integrated therapies, pharmacogenomics-based drug response tests, anti-aging, stem cells transplantations in blood-related disorders, biomaterials, 3D reconstructions, orthotics, radiation, chemoprotection, personalization, skin and hair treatments, infertility and healthcare products. DiponEd provides new devices and technologies along with the solutions which are developed in-house and are at feasible costs, usually at a fraction of the costs from the US or Chinese. The firm is also integrating all the services under one roof to emerge as a one-stop solution provider for personalized medicine services. The company is also contributing towards the corporate social responsibility cause through its primary health care initiatives at rural/semi-rural townships. Especially, in the areas of diabetic foot ulcers and pain management curated for the unprivileged section of the society. Remarkable Footprints DiponEd emerged as Elevate 100 Award Winner, 2017. It was also selected as the Emerging Leader in the Medical Devices industry in India, for Merisis Therapeutics point of care kits presented at THE HEALTHCARE- PHARMA & MEDICAL DEVICES SUMMIT & EXCELLENCE AWARDS 2017 on 4th August 2017 at St. Regis, Mumbai. The firm received Karnataka State's quality leadership award, by the World Quality Congress & Awards in 2019. Under the leadership of Dr. Kaushik Deb, Founder, CEO, and Managing Director of DiponEd – the company has developed more than 30 patented products and services. It is “Our concepts in personalized treatments are new to the health care ecosystem in India and also in many parts of the world. We are spending a lot of time and effort in creating awareness”
  • 14. collaborating with more than 20 international and National labs and education institutions to develop its unique line of therapeutics. He also established the DiponEd Institute of Regenerative Medicine (DIRM), offering Certificate Course in Regenerative Medicine (CCRM) and Fellow Program in Regenerative Clinical Medicine (FRCM) with the DDM university. He is the Director of Indian association of laser therapies (IALT), and Secretary, Society of Tissue Engineering and Regenerative Medicine (India). He has done M.Sc, MD (IM), Ph.D., Post Doc Associate (USA, Canada), EGMP (IIM-B) and FRHS. He has been awarded the Govt of India DBT's, Overseas Bilateral exchange Associateship with Ottawa General Hospital, and the Indian National Academy of Sciences (INSA)- bilateral exchange award with the Czech Science Academy. He has published over 70 peer-reviewed research papers, abstracts, and book chapters, and is also an active reviewer for 4 international journals and editorial board member for 5 international journals. He has authored the book entitled ‘Stem Cells; Basic and Applications’ published by McGraw Hill New Delhi and ‘Stem cell Technologies’ by McGraw Hill, New Jersey, USA. Dr. Kaushik has developed/ patented platform technologies for personal health care and personalized therapies in cancer, radiation, hair and skin regeneration, Oestochondral defects, organ-specific aging, age-associated conditions, diabetics AMR, 3D tissue engineering, etc. Dr. Kaushik has been awarded the Govt of India DBT’s, Overseas Bilateral exchange Associateship with Ottawa General Hospital, and the Indian National Academy of Sciences (INSA)- bilateral exchange award with the Czech Science Academy. He has also been honored with MED ACHIEVERS ICON AWARD for his work in the field of Healthcare. He and his team are developing 3D bioprinting and 3D printing services, under the 'Uchhattar Avishkar Yojana' award, supported by the Ministry of Health Government of India. DiponEd is setting up novel Artificial “Our vision is to address unmet medical and healthcare needs across the globe through innovation, science, and modern technologies” intelligence platforms P4M Cure Clinic and apps, and new algorithms are being derived to learn about healthcare and diseases. All of this while creating integrated clinical data for Predictive, Preventive, Participatory and Personalized medicine, in collaboration with hospitals globally. The R&D team is working on several unique aspects of modern health care challenges like Drug interactions in patients, Drug overloads, Chemosensitivity, Liquid biopsies, Genomics, Proteomics, Metabolomics, Molecular and Genetic diagnostics, and Prognostics, cellular biological APIs, therapeutic devices (Merisis Therapeutics). It is also creating other personalized products in cancer, nephrology, podiatry, DFUs, burns, sports injuries, orthopedics, dermatology, etc. “We are a bio-intelligent solutions company with a focus on unique formulations and solutions. All our health care products are derived out of in house R&D using data mining, lab tests, artificial intelligence applications, and advanced biotechnology. We strive to be faster, better and cheaper from any other products and services company,” concludes Dr. Kaushik. The Most Innovative Bio TechSolution Providers to Watch in 2019 1
  • 15.
  • 16. ACCUREX BIOMEDICAL he world of In Vitro TDiagnostic Device (IVD) is taking the centre stage with existing and budding players disrupting and creating their own pathway. Contributing to this journey is Accurex Biomedical Pvt. Ltd. (ABPL) that is unlocking countless opportunities for the betterment of the masses by offering novel medical diagnostic solutions. The below excerpt is an exclusive interview with team ABPL showcasing their distinctiveness and curated acumen which helps them in being ahead of others. IS: Share some insights about your company, its inception story and the vision behind. Team ABPL: In 1984 almost 100% of the diagnostic reagents were imported into India. Mr A.J. Thakur founded Accurex in 1984 to indigenise the manufacturing of imported reagents in India. Accurex was the first company in India to manufacture urine test strips and enzymatic clinical chemistry reagents in India. This was the beginning of the IVD clinical chemistry reagents manufacturing industry of India. The journey of Accurex since 1984 has been on a growth trajectory. With the continuous launch of innovative products, Accurex has created a brand name in the Indian IVD Industry. IS: What your products & services' ambit hold? Team ABPL: In the laboratory diagnostics space Accurex offers the entire range of clinical chemistry and haematology reagents. In Instruments, we offer semi-automated, fully automated clinical chemistry, 3 part and 5 part haematology analysers. We also offer urinalysis test strips, urinalysis meters and immunology rapid tests. In the Point Of Care (POC) segment we offer blood glucose meters, haemoglobin meters, HbA1c meters, immunofluorescence meters, uric acid meters and respective test strips. IS: With regards to your organization’s profound industry experience, how do you think the diagnostic industry and market have evolved and what can be expected in the forthcoming years? Team ABPL: The diagnostics industry is getting disrupted by point of care (POC) testing. Point-of-care testing (POCT), or bedside testing is defined as medical diagnostic testing at or near the point of care—that is, at the time and place of patient care. This contrasts with the historical pattern in which testing was wholly or mostly confined to the medical laboratory, which entailed sending off specimens away from the point of care and then waiting hours or days to learn the results, during which time care must continue without the desired information. POC testing is getting popular in the medical diagnostic industry. Through POC testing the lab tests are available at the doctors and patients at home. This is convenient for the patient. Accurex has launched a complete range of POC products to ensure faster and convenient testing. IS: What are the benefits gained by your clients/users from your products/solutions/services? Team ABPL: Diagnostics affects 70% of medical decision and in only 3% of the healthcare costs. There is a dire need in India to reduce the ever- increasing cost of health care and diagnostics plays a pivotal role in the efficient use of resources. TESTING LIFE AND SAVING LIVES January 2020|14
  • 17. Mr. Abhinav Thakur Managing Director January 2020| 15
  • 18. India is till date dependent on imports for its IVD needs with almost 80% of IVDs are being imported. The cost of manufacturing in the developed world is many times higher than the cost of manufacturing in India consequently by manufacturing indigenous products Accurex lowers the healthcare costs in India. By using preventive diagnostics effectively we can prevent diseases in advance and significantly lower the cost of health care in India. Its an honour for Accurex to contribute to the reduction of healthcare cost to patients and ultimately to our country. IS: Tell us about Mr Abhinav and his contribution to the company and its success. Team ABPL: Mr Abhinav Thakur was studying in the USA when, unfortunately, his father passed away prematurely. He came back to India to run the company for his family. At that point of time the motivation for him was survival of the family business. Now the motivation for him is to grow the company so he can have an impact on the healthcare industry by manufacturing affordable and high- quality medical diagnostic products. Since his appointment as Managing Director, APPL has grown 4.2 times in revenue and our team size has increased from 90 to 170 individuals. We have moved from a diagnostic reagent company to diagnostics reagents and instruments company. IS: In what ways does your organization contribute towards the Corporate Social Responsibility cause? Team ABPL: We at Accurex believe wealth creation leads to wealth distribution. So, it’s our endeavour to create prosperity so we can contribute towards the economic development of India. IS: What obstacles and/or limitation does your organization face while growing, sustaining or retaining its clientele? Team ABPL: The diagnostics industry is capital intensive because the business model in our industry is moving towards analysers being placed on reagent rentals. To place analysers on reagent rental we need a large capital investment. This is the challenge we face in our industry. IS: Could you list out the most growth-deteriorating challenges for your organization till date? Team ABPL: Service is key in the diagnostics industry. The analysers need a fast turn around time (TAT) in case of breakdown. Providing service in a large geographical country like India with underdeveloped infrastructure is a challenge. IS: What does the future hold for your organization in terms of internal as well as holistic development? Team ABPL: Now the motivation for Mr Abhinav is to grow the company so he can have an impact on the economic development of our country. He strongly believes that economic development is the antidote of poverty. The next major milestone for him in this decade will be getting Accurex listed on the stock exchange. IS: Would you like to highlight any awards, accolades or testimonials your company has achieved throughout? Team ABPL: Over the years we have achieved various awards and recognitions such as • Ranked #10 in BioSpectrum Top 20 Indigenous Medical Devices & Diagnostics Companies 2019 Survey • Selected as “Visionary leader in Healthcare 2017” by Medgate Magazine • Ranked at number 19 BIOTECH companies ranking by Biospectrum Magazine analysis done by KPMG • Altina Entrepreneurs Excellence Award,2017 in the healthcare category • India’s most Innovative and Valuable Medical Devices Company 2017 Interview With Insights Success January 2020|16
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  • 20. While everyone speaks about how innovations are changing the face of the world, few talk about the research that goes behind it. What we are currently enjoying as the latest technology or an innovative marvel, might have actually taken years or may be decades of research to develop into its current form. As such, it is crucial that research companies, especially start-ups, be given a conducive environment where they can flourish to help mankind. Bangalore Bioinnovation Centre (BBC) is one translational research centre catering to the needs of startups in the broad areas of Life Sciences viz., Health Care (MedTech/ Pharma/ Bio-Pharma), Agriculture, Food/Nutrition, Industrial Biotechnology and Environmental Biotechnology. BBC is an initiative of Department of IT, BT and S&T, Government of Karnataka with funding support from Department of Biotechnology, Government of India. The centre is located in Bangalore Helix Biotechnology Park at Electronic city, and thrives between academic institutions like Institute of Biotechnology and Applied Biotechnology (IBAB), Centre for Human Genetics (CHG). The centre started functioning since April 2015 and has currently 38 startups being physically incubated and 7 graduated companies. BBC is envisioned to nurture bio-startups ecosystem and catalyse it's growth to benefit the society at large and contribute to bio-economy. As a not for profit company and relationship builder, BBC supports quality programs and trainings that ensure strategic and progressive growth of innovation and entrepreneurship in Life Science. Recently BBC received the Award for being finalist in National Entrepreneurship Award National Centre for Excellence conferred by Chief Secretary to the Government of Karnataka, Shri Vijay Bhaskar T M, IAS Nurturing Start-ups Bangalore Bioinnovation Centre provide services such as Infrastructure/ Equipments, networking, branding, funding and mentoring to startups in the field of Healthcare, Agriculture, Food/Nutrition, Industrial Biotechnology and Environmental Biotechnology. These startups utilize the facilities to conduct R&D and translate them into products. Many of the incubatees have commercialised their products based on technologies like Artificial Intelligence for diagnostic purpose, Point of care devices, Non- invasive testing devices, Customisable 3D printer, 3D printed skin, kits for diagnosis and Prosthetic foot. Some of the startups involved in developing breakthrough products are as detailed below. OmiX Labs(OmiX) developed “The OmiX Technology Platform” designed to look at gene signatures for Antimicrobial resistance. They are also providing services pertaining to unitized room-temperature stable kits and automated assay setup. Pandorum Technologies Private Limited (PTPL) is engaged in development of Bio-Engineered Human Cornea that can be used as Platform for in vitro toxicology and safety assessment and Lab Grown Mini Liver that can be used as Platform for pre-clinical drug discovery and development. Innov4sight Health and Biomedical Systems Private Ltd. is working on a Bangalore Bioinnovation CentreHelping Innovative Ideas Hatch January 2020|18
  • 21. device to simulate fertility factors called “FERTIMULATOR”. They are also conducting research on Biologically Activated Peptide Concentrate (BAPC) used for fertility factors regeneration. Next Big Innovations Lab (NBIL) a startup involved in development of Innoskin®, a 3D Bioprinted Human Skin and “TRIVIMA”, NBIL’s 3D Bioprinter. These are innovative breakthrough products that have gained recognition and award from established companies like Merck from Germany. Enriching Mankind The incubatees, both current and graduated, over time have developed products that are now helping companies and end-customers in several ways. Here are some products that are making a marked difference: Innov4sight Health and Biomedical Systems Private Ltd. came up with two technologies in the field of fertility treatment. One is FERTIMULATOR, a simulator machine and one of the prime products of Innov4Sight which is covering simulation for fertility specialists and embryologists to simulate Oocyte Retrieval (OR), Intra-Cytoplasmic Sperm Injection (ICSI), and In Vitro Fertilization- Embryo Transfer (IVF-ET). The newer version of FERTIMULATOR is incorporated with Regenerative Medicine (RM) services that is intended to help IVF experts in treating endometrial deficiency, one of the key factors causing infertility. Next is the BAPC as mentioned earlier, which is used for endometrial regeneration. The future prospects of this medicine is treatment of infertility in women to induce ovarian regeneration and oocyte production. OmiX’s portfolio of products and services aim to create impact on millions of lives. They offer a “Insights Put Into Action” Dr Jitendra Kumar Managing Director The Most Innovative Bio TechSolution Providers to Watch in 2019 1 January 2020| 19
  • 22. platform for early detection and more accurate identification of organisms causing infections. At the same time, they are also determining whether the infection is potentially drug resistant. OmiX Labs can conduct drug resistant tests in only three hours, whereas conventional tests require a minimum of three days in laboratories equipped with microbiology facilities. PTPL’s two breakthrough technologies include Bio-inspired Corneal ‘ink’ that can be used as ‘Liquid Cornea’ for therapeutic application and to ‘print’ Corneal lenticule for human implantation for treating visual impairment due to corneal defect. This has a social impact as this will restore the sight of many people with corneal defect. The other invention is mini liver platform (normal and diseased models) which will be used in pre-clinical drug screening (discovery and development) by the pharmaceutical industries/CRO’s. This model will significantly reduce the cost and time of new drug discovery resulting in affordable drugs available to the patients. NBIL has focussed their research on finding alternative for testing of products on animals, which is currently banned and restricted. The current gold standard testing alternative, 3D cultured skin, is priced extremely high and has inconsistency from batch to batch. This has motivated the startup to develop Innoskin®, an economical and consistent product. Added to their portfolio is NBIL's patented 3D Bioprinting technology which allows positioning of cells with micron level precision, thereby enhancing cell-to-cell interaction within the tissue construct and reducing the chances of batch-wise inconsistency. An Experienced Motivator Dr Jitendra Kumar, Managing Director, holds a PhD in Biotechnology from Institute of Microbial Technology, Chandigarh, a prestigious national laboratory affiliated to Jawahar Lal Nehru University, New Delhi. Subsequently, he moved to University of Illinois at Chicago, where he worked on Leukemia. In the next stint as a Post Doc at Ohio State University, Columbus OHIO (USA) he worked on various cutting edge research projects. He is the author on several internationally acclaimed peer reviewed papers. He holds an MBA degree from prestigious Fisher College of Business at Ohio State University. After returning from US, he joined as a Vice- President of Life Science Incubator at IKP Knowledge Park, Hyderabad where he was involved in actively mentoring Incubatee companies and creating pipeline of entrepreneurs through innovative models of team building around the technologies. As the Director & Head of BBC his current focus is on Incubating Innovations is Agriculture, Food and Nutrition, Biofuel/Bio-energy and Pharma/Healthcare. He is working closely with Karnataka Biotechnology and Information Technology Services (KBITS), Department of IT, BT and S&T, Govt of Karnataka, to create a vibrant Life Sciences Innovation cluster in Bangalore. Helping Start-ups Grow The startups at BBC are focussed primarily on delivering solutions to problems prevailing in the biotech market. The areas of research bridges the gap in technologies and hence offer competitive products to meet the demands of the market. This approach has fetched the startups competency in market. The key impediment for the start- ups to grow is the non-availability of funding. BBC facilitates government funding called “SEED FUND” for development of innovative ideas, incubation, entrepreneurship thereby creating a bio-cluster working in synergy with ecosystem partners like other similar- minded startups, SMEs, industry, investors, government organizations, policy think tanks and business organizations. This paves opportunities for networking to progress in their research and development. However, the main challenge faced by these startups during translation of research into products in market is the requirement of substantial investment. This stymie the growth and vision of startups and many fall into the “valley of death”. Positive Vibes for the Future BBC is mandated to nurture start-ups working in the broad areas of Life sciences with an aim to improve the quality, efficacy and sustainability of healthcare, agriculture, industrial & environmental biotechnology products. A holistic development can be achieved only when diversity and inclusivity is embedded in startups from the beginning to bring out inter-disciplinary innovations. BBC is fostering such a holistic growth among the startups through interaction and learning and for the greater benefit of society. January 2020|20
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  • 24. SocialMedia Marketing he absence of pharma brands on social media creates a significant void of reputable healthcare information to aid Tpatients,” writes Dawn Lacallade, LiveWorld’s Chief Social Strategist. Social media infiltrate virtually every facet of an individual’s digital life. Today, patients are using social media as a major source of information and healthcare research. Thus, it is essential that pharma companies should be present on social media to provide full and accurate information to the consumers. To comprehend how social media can assist patients, it is crucial to understand what compels people to use social media as a source of information. Social media allows interaction among people which involves exchange and creation of information. It is the perfect conduit for pharmaceutical companies to connect with their customers, patients and physicians. According to the current FDA regulations, pharma companies are not able to easily join in a conversation to provide accurate and balanced information. Regulations dictate that, in a single social post, brands are required to provide precise facts on the benefits and hazards associated with conditions and products. Due to the character limitations on many social media platforms, most pharma companies prefer to stay out of the conversation. This results in circulation of falsified information. This information can be either marginally inaccurate or significantly harmful. “ for Market Dashboard January 2020|22
  • 25. Although the communication of pharmaceutical industries is highly regulated, they are gradually adopting social media platforms to reach and interact with consumers and healthcare professionals. Here are some of the top social media practices to look out for: Crafting Customer Experience Several marketers think that their job is finished once the sales team takes over, but in reality, it is just the beginning. The way people experience your brand will impact the way they think about you, which will have an enormous effect on the success of your company in the long run. Devoting a part of the marketing budget to nurture the existing clientele will make their experience splendid and thus promote brand loyalty. It is also crucial to respond whenever your brand in mentioned publicly, whether positively or negatively, which will help cultivate a strong and lasting relationship with your customers. Younger generations are increasingly withdrawing from traditional social media platforms and adopting more innovative channels that are more intimate in the way of communication. To keep up with this challenge, companies need to find a way to automate the process wherever possible. Regulating Content Pharma companies need to develop content marketing strategies that merge each piece of content on every channel with their organization’s objectives and customers’ needs. Creators need to have a clear business objective including the value that will be delivered to distinct audiences. All companies need to have a social media compliance officer who will work closely with a corporate legal counsel and develop a complete strategy and decide if there will be consolidated social media posting or if individual employees will have the consent to participate. And lastly, it is critical that all employees understand their role in corporate social media and be trained on the rules. Overall Integration Pharma companies should stop thinking about content marketing and social media as add-ons. To boost their outcome for clients, content and social marketing need to be a part of almost every program. To develop a fully integrated program, companies need to involve influencers and content marketers during the initial stages. Implementing an organized approach to content and moderation will not only optimize the processes, but also aid in assuring authorities that all the bases are covered to protect and provide value for the brand. Investing in Employees An independent survey discovered that 72% of social media users expect response within an hour from the brands they follow. This has caused brands to start heavily investing in cross- functional social media teams that can keep up with the increasing number of client pings January 2020| 23
  • 26. every day. Encouraging and incentivizing team members to share brand messages on their own social media accounts, is predicted to be a game-changer in the coming days. However this cannot be forced, it is essential for employees to want to share company posts, and along with this the content has to resonate with their own audiences. Influencer Marketing Influencer marketing will continue to develop and become an even more established part of the strategy. Currently many brands try influencer marketing and fail as it is not easy to find effective influencers. Additional data will help in selection of the right influencers and analyze the results from influencer campaigns. Today, in healthcare, influencers are often regular people. Some are directly affected by a disease or are being treated with a specific product, while others have gained a lot of knowledge about a condition and are considered as Subject Matter Experts. The common trend is to select someone who has an ever-increasing community of followers who value their opinion. Numerous companies still think of social media as merely a marketing tool which is not true anymore. Consumers learn about products on different social networks and seek customer service on messaging channels. Moreover, good storytelling has always been an essential part of effective marketing. But social media is changing the way audiences consume stories and pharma companies will be required to keep up with the evolution of social storytelling if they want to remain relevant. Yet there is still a note of caution with compliance being the foremost priority of pharmaceutical companies. But as industries are starting to adopt social media without clear regulatory guidance, remaining compliant will be the main challenge to face. BUSINESS MARKETING January 2020|24
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  • 28. Dr Ritu Hinduja is an MD, MRM (UK), and DRM (Germany) who has completed her Fellowship in Reproductive Medicine (India, Spain, Israel). She is a certified Genetic Counsellor and a well- known medical practitioner. Dr Ritu specializes in Reproductive medicine and Infertility treatment and has an experience of more than a decade for the same. For her dedication and contribution, she has been honoured with various prominent awards like FOGSI Chorion Award for Best Research, FOGSI- Kumud Tamaskar Award for Best Research in Infertility, and FOGSI- Dr Shanti Yadav Award for Infertility, to name a few. Insights to Choosing the Right IVF Center About The Author Dr Ritu Hinduja Senior Consultant – Reproductive Medicine, Nova IVF, Andheri (Mumbai) January 2020|26
  • 29. Reproductive medicine is an ever advancing field of medicine which provides a ray hope for couples who are battling infertility. IVF is usually effective, though not always immediately for all women, research suggests that if you’re considering assisted reproductive technologies to help you conceive, it is suggested that you chose your fertility clinic well and that can improve your odds of a good outcome. But with so many clinics out there to choose from deciding which one best meets your needs can feel a bit overwhelming. You can use the following pointers to help you chose a clinic that meets your needs. Do Some Research All fertility clinic may apparently look the same, but they are not, and it does not hurt to do your homework. You may want to consider enquiring about the success rate of the clinic. While enquiring about the success rates it is advisable to compare oranges to oranges so compare the success rates for your age group and also the kind of treatment that you plan to do. Once you are convinced about the success rates it's a good idea to have a look at their accreditations you can either look for ISO, ISAR or a NABH accreditation in the Indian subcontinent. Also make sure that the clinic is registered with the ICMR (Indian Council of Medical Research) Ask Questions Before you commit to an IVF clinic its always best to ask all the questions that come to mind even if you think they are silly. It’s your treatment and you need to be at peace at what you are proceeding with and it’s your right to know every pro and con about the treatment or any other query that may come to mind. Some of the questions you may consider asking: • The process of IVF per se • How many embryos do they transfer? • What is their embryo freezing program like? What is their contract time period? What will be renewal clause be? • Do they prefer a day 3 or a day 5 transfer? • The technique of fertilization --- ICSI for all or IVF for selected cases? • Do they have an identification system in place for the Gametes? • How are donors screened and allotted? • Will you need genetic screening? • Will you need sperm selection techniques? • What will happen when you get pregnant? who will you follow up with? • What will happen if you don’t get pregnant? • If attempting genetic screening – you may want to ask which lab they are associated with for the analysis? • Do they have an in house full time andrologist and embryologist? • Is it an all under one roof facility? Find out if they have a Psychological Counsellor or a Patient-support Group It's important for a fertility clinic to offer indicated medical treatment to help you conceive but it’s also important that there is enough emotional support available while you are embarking on one of the most emotional journeys of your life. Also, if the sessions with the psychologist are chargeable or are free of cost. Consider the Monitory Factors Always take your financial counselling in written from the clinic. Consider have they given you all the inclusion and exclusion criterion’s in written. The inclusion criteria you may want to look for are gonadotropins, blastocyst transfer and luteal support medicine till Bhcg. Always gauge how transparent they are attempting to be in their pricing. Trust your Instincts When you’re considering a fertility clinic, always trust your gut feeling. I think patients’ gut feelings are usually pretty good. Life’s most precious commodities are your gametes and hence any decision you take regarding them has to be carefully contemplated hence it is important that you get a feel of the people who are going to be handling your gametes. Consider the professionalism of the staff of the clinic and how they treat you , pay attention to what they say to you and how professional and genuine does their care feel to you and does their care make you feel comfortable and at ease or do you feel rushed or ignored. If Applicable to you may want to find out more about the Special Program the Center has • Who is the andrologist attached with the center if you are going to need testicular sperm extraction? • If you are looking for social fertility preservation: then you may want to know about their oocyte freezing facilities. Find out how many times you may need to do egg retrievals to freeze the optimal number of oocytes. What is the payment structure? How long will the oocytes be cryopreserved according to the initial contract; how will the renewal clauses be. • Fertility preservation program for cancer patients. Even after all the above pointers only you can know which clinic suits you best and always remember A great fertility clinic isn’t just one that can give you effective treatment, it is the one with staff that is compassionate, has transparent and clear financial counselling, smooth administrative processes and a system in place for exceptional emotional support. January 2020| 27 Experts Opinion
  • 30. The Indian Biochemical sector is initiating breakthrough enactments and is laying the foundation of a stronger growth trajectory. With this immense growth potential, the sector will continue to play a pivotal role as an innovative manufacturing hub and unlock countless opportunities for today and tomorrow. Acknowledging this scenario, organized manufactures are offering exclusive solutions for the betterment of the economy alongside delivering quality to the core. Founded in 1975, Sisco Research Laboratories Pvt. Ltd. (SRL) is one such organization that stands amongst the oldest and most respected manufacturers of specialty fine chemicals, microbiological, nanotechnology and biotechnology reagents. It's an ISO 9001-2015, CGMP, FDA, and CE certified organization that employs about 300 personnel to manufacture. Headquartered in Mumbai, SRL effectively services the needs of scientists, researchers, quality control managers of industries, researchers of institutions and academic bodies. Today, the company stands amongst the five leading Reagents and Biochemicals providing companies in India. It's patronized by various National Laboratories, CSIR, ICMR, ICAR, DRDO, IITs, NITs, NISER institutes and National Universities thereby, leading to accreditation and acceptance by the multinationals, Indian manufacturers and even overseas buyers. Apart from all this, SRL also makes its modest contributions towards various CSR activities. The Success Story Mr S. K. Agarwal laid the foundation of SRL way back in 1975 when India's premier Research institutes and academic bodies such as Universities and Colleges were Sisco Research Laboratories:A Name Synonymous to Quality Reagents and Biochemicals relying wholly on imported reagents and chemicals. Being the Managing Director, his sole aim was and is to contribute to this ever-increasing ocean of scientific research and learning in the country. At that point in time, he faced a plethora of challenges concerning designing, production & testing methodologies, capital, operations, and staff training. Making staff understand the importance of high-quality testing and manufacturing standards was not an easy task for the company. Also, customers preferred to import chemicals from the leading companies in the world rather than embracing Indian products. Keeping up with times and acknowledging these trends, Mr Agarwal embarked on a journey of manufacturing speciality chemicals and reagents at par international quality in India. With the passage of time, his curated acumen and consistent efforts successfully carved out affordable pricing strategies that have the potential to satisfy the needs of the customers with limited financial grants. Currently, his leadership is helping the company in contributing to the growth of scientific research in India. The young dynamic Directors - Mr. Akash Agarwal and Mr. Vikas Agarwal (Grandsons of Mr. S.K. Agarwal) have taken the SRL's visions and goals to a broader and higher mission. Their education, experience and leadership is enabling the company to penetrate many new markets (Pharma, FMCG, Cosmetics & R&D etc.) and reaching to every corner of the world. They are also upgrading and up- scaling the product range of the company by introducing newer reagents in the field of diagnostics, nano-technology, molecular biology and PCR related reagents. January 2020|28
  • 31. Meet the Cornerstones Mr Ramesh Agarwal, Director and son of Mr Agarwal is associated with the company since last four decades and has been especially credited with the procurement of raw materials for the company with his business acumen in bulk chemical industry. Mr Akash Agarwal and Mr Vikas Agarwal, the young Directors of the family-owned company have introduced many verticals of management at the head office. While Mr Akash has completed his Chemical Engineering and MBA from USA, Mr Vikas has done his Post Graduation in Commerce and MBA from UK. They have been driving digitalization and computerization in operations at all levels for faster growth within India and overseas. A biochemist devoted to R&D, Late Dr M. R. Raikar pioneered the development of various reagents under the leadership and guidance of Mr Agarwal. His knowledge and experience assisted the company in launching its first manufacturing unit in Kashimira in Mumbai. A Reader in Mumbai University and a devoted student of Organic Chemistry, Late Dr Pandit had been instrumental in establishing the second manufacturing unit in MIDC, Turbhe, Navi Mumbai. The Corporate R&D and Production Manager of the company who stands amongst the proficient R&D scientists having experience in UK, US, and MNC pharma companies has led the team of chemists at Turbhe factory to effectively synthesize highly purified reagents, phase transfer catalysts, and specialized solvents thereby adding to the growth of the company. The Corporate Quality Control Manager of the company who heads the quality control department at the MIDC, Taloja factory has been accredited with the development and modifications of analytical methods of hundreds of biochemicals, reagents, and solvents. A versatile manufacturing microbiologist, who Heads the Microbiology Division of the company is helpful in The Most Innovative Bio TechSolution Providers to Watch in 2019 1 We ensure that the products we manufacture give the desired consistent results batch-after-batch “The Company vision is “ to serve the endless process of science ‘‘ ‘‘ Mr Akash Agarwal Director Mr Vikas Agarwal Director January 2020| 29
  • 32. developing a new production department of dehydrated culture media, playing a pivotal role in catering to health care, environmental, and microbiological quality control. The Chief Accountant has been aptly instrumental in handling the financial and accounting management of the company. The Regulatory Personnel has been instrumental in introducing several regulatory systems like ISO, CE, GMP, and VQs to meet the industry’s and government’s mandatory requirements. Rewards & Recognitions Mr S.K. Agarwal was awarded the ‘Indian Achievers Award' in 2014 for Industry Development in the field of CSR and Sustainable Development. A renowned media company Bio Spectrum recognized SRL amongst the ‘20 Top Biotechnology Companies’. It had also published a profile of Mr Agarwal, as a leader in the field of biotechnology-related reagents in the country in the year 2013. In 2010, he was felicitated by ISGF / AISG in recognition of his contribution to Scout and Guide Fellowship during the past 50 years in India. He was also a member of the ISGF World Committee from 1993 to 1999. He has attended & successfully completed MIT Management Executive Education (Leading Organisations and Change) in 2018 from EMERITUS institute of management, US. Outperforming Own Milestones SRL manufactures and provides more than 6000 products across 15000 Stock Keeping Units (SKU’s). Its product menu includes Organic & Inorganic reagents, Biochemistry and Molecular Biology reagents, Nanotechnology products, Microbiology dehydrated culture media and PCR reagents. The company’s products are quenching the needs of various industries like Pharma, FMCG, Cosmetics, etc. Companies embrace these products for their R&D and pilot-scale & bulk production. However, the introduction of newer range of diagnostic reagents has created a shift in the buyers’ preference for SRL products alongside gaining the advantage of economical prices and promoting availability. With the expansion of its export business in the Indian subcontinent, Far-east, Europe and the US, SRL is all set to observe growth rates in excess of 30%-40% on year-to-year in the next 5 years. Explore more on srlchem.com Mr S. K. Agarwal MD Mr Ramesh Agarwal Director January 2020|30
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  • 34. Biobanking is going to be the new world order to provide first-in-class transformative medicine replacing hospitals and based medical, healthcare institutions. As far as the bio-samples are considered, storing for applications will evolve to become a blue-chip industry. Biobank derivatives put to applications are forecast to be pegged at 500 billion global market opportunity covering big data in genomics, drug discovery, development, CAR-T cell therapies, transplantations, repair, and regeneration. Transcell Biolife was founded to be a biobank for the intended applications; built on preservation theme and technology translated to apply. In Biolife’s context with credible in- house R&D, Intellectual property surrounding the story as translating the prowess of adult stem cell technologies to the intended applications, thebiosamples derived stem cell units and data are invaluable assets in the repository. The belief and the conviction have been handling the right kind of bio-samples, derived cellular platforms depending on the use, with Biolife’s team emerging as revenants in the wake of industry transformation, adaptation. With a track record of offering bio storage products and related services, Biolife today has positioned itself addressing expectant families and families with kids aged between 5 and 11- year markets. The vision of the company is to become an epicenter biobank for Asia facilitating transformative medicine. Biolife is a revelation from India in the field of biobanking with applications shown beyond autologous presentations. Extraordinary Services and Products ScellCare ScellCare is into storing umbilical cord, bone marrow and bio-sample derivatives (cellular units and stem cell transcriptomics). Collection is non- invasive, painless, and poses no risk to the donor, while source is being categorized as biological discards. In India, blood forming (hematopoietic) stem cells from bone marrow or umbilical (nadi) cord blood are routinely used to treat blood cancers and different blood disorders as Standard Care in managing 40 different kind of diseases. The stem cell transcriptomics derived report is predictive (not diagnostic) in nature with details on the donor stem cells genomics in readable format. This is completely next generation feature of the biobanking service that Biolife has integrated into it’s regular offering. ToothScell Dental stem cells are adult stem cells found in wisdom teeth and baby teeth. They are being studied for applications in regenerative medicine and dentistry while over 2000 clinical trials are ongoing at global level. ToothScell program acquires donor’s tooth stem cell nucleotide sequence before cryopreserving the units in the repository. Identification of disease genes from the sequence can have applications in proactive healthcare approach and predictive testing. Relationship of dental stem cell molecular markers with other systemic illnesses like that of heart ailments, diabetes, immune disorders are known. ToothScell is a comprehensive and progressive relationship with it’s clients offering precious service from collected bio-sample. Benefits for Clients Insightful, Latest, Modern, Credible, Transcell Biolife’s laboratory driven original data converted to users’ precious experience in the form of biobanking related solutions. Biolife empowers them by offering these solutions to act informed addressing their family’s wholistic medical, healthcare requirement. The Leader with Vision S Dravida, the Founder, and CEO is a scientist by profession, practicing to translate the group’s proprietary stem cell platform technologies to applications. With utmost dedication and focus on delivering maximum with minimum input philosophy, she has orchestrated Biolife for preserving all precious things to offer the intended applications keeping stakeholder value in mind. It is her vision, which is built on the team’s strengths to become Asia’s epicenter biobank playing a key role in facilitating the derived applications, that sets Biolife apart from the rest of the players. Transcell Biolife The Next Generation Biobank with Global Outlook January 2020|32
  • 35. L Krishna is the head of Operations with Biolife team. He has been the core member with technical, and medical background contributing to the success of present operations. His alignment, passion for the company’s mission and vision translating to setting an example with Biolife achieving operational efficiency is a rare talent. He plays a crucial role in bridging the facilities and the field dynamics with commitment. Adopting Digital Disruptions The company believes and practices original research driving the business offerings from Biolife and so has built unique internal complex processes customized connecting digitization. Starting from the client enrolment, till the promised service from the Biobank is delivered, the entire operational (technical and sales) process is wired while handling privacy related matters as per the rule of the country. Overcoming the Challenges “We operate from India and this market is crowded with known businesses, models, markets for example cord blood banking which is commoditized. So, it was difficult for us to get practitioners, evangelists, ambassadors, sales champions in the beginning who could proactively be our referral points promoting our story that has unique differentiators with proven track record”, S Dravida recollects. Further, she says, “To our honest self and after facing the market and the customers for the past 7 years continuously sharing our ups and downs that are different from the others, Biolife stands tall today with great connection established with needy market. The discovered growth formula addressing bio-sample storage disruptively is the ground breaking strategy breaking all the growth deteriorating challenges in this space.” The vision, operating team’s adaptability, ability to connect with the user (B2B or B2C) on Biolife’s strengths, core capacities have set any competition at bay in the market. The Future Roadmap “As far as Biolife’s internal growth in India, it is planned to be organic by strengthening facilities, adding channel partners from North and Eastern states to handle volumes while thegrowth formula embraced by Biolife positions the company as epicenter biobank in Asia building assets in the repository to apply”, S Dravida expresses her view regarding the future road map for the company. Biolife operates with a purpose and the fact that it has growing clientele and collaborations in India is a testimonial in its language. Meaningful innovation does not need to be based on outright invention. Rather, there is an exhilarating shortcut. It is based on bold, new combinations of already existing components that simultaneously unlock heightened levels of consumer value and reduce costs. -Gabor George Burt S Dravida Founder & CEO The Most Innovative Bio TechSolution Providers to Watch in 2019 1 ‘‘ ‘‘ January 2020| 33
  • 36. Biotechnology is a the exploration and development of various biological processes to achieve mainly industrial and various other purposes cultivation of the plants, and improvements through breeding programs. The processes also employs artificial selection and hybridization which emphases its functionality. At present, the modern usage also includes genetic engineering as well as cell and tissue culture technologies. In earlier days biotechnology process was initiated by farmers who developed improved species of plants and animals by cross-fertilizing or cross-breeding. In recent years, biotechnology has expanded its core functionality widely which now focuses on sophistication, scope, and applicability. A well-known and author and writer is vague and can be unsubstantial, for example, Clayton Christensen share his views as, "There are other dimensions of biotechnology. If you think of biotechnology like the Internet, it's not a category - it's an infrastructure that can be deployed to sustain or disrupt. In healthcare, the most complex problems at the high end have to be dealt with in a problem-solving mode by the best, most experienced physicians you can find.” Biotechnology is immensely contributing towards agriculture which enhances its functionality to the next level. Agriculture aspects have extremely changed with biotechnology functions and increase readability of the process. What is Agriculture Biotechnology? Agricultural Biotechnology is also known as Agritech. It is an area of agricultural science involving the use of scientific tools and techniques. There are several techniques used in agriculture biotechnology such as Genetic Engineering, January 2020|34 Agri Tech
  • 37. Protoplast Fusion: Protoplast fusion is also known as Somatic fusion. It is a type of genetic modification in plants by which two distinct species of plants. In this method, it includes joining of cells or cell components to transfer traits between species. Transgenics: Transgenics is the method which involves the insertion of one piece of DNA into another organism's DNA. It works in order to introduce a new gene into the original organism. This addition of genes into an organism's genetic material creates a new variety with desired qualities. Impact of Agriculture Biotechnology on Economy and Social Life The technology used in agricultural productivity improved its usability and functionality with some major factors such as combine harvesters, chemical fertilizers, and the green revolution. Like every technology, agricultural biotechnology will also have its major impact on economic and social. In agriculture, crops using biotechnologies have improved its quality and also been used safely with benefits. The technology influences the whole process by the reduction of pesticide use. At present agricultural biotechnology, one of the factors that influence the health and welfare of the farmers and other citizens in the developing world. Influence of Agriculture Biotechnology in the Future The aim of agricultural biotechnology is to present the functionality of the applications used in agriculture biotechnology. The applications are eagerly awaited to increase Molecular Markers, Molecular Diagnostics, Vaccines, and tissue culture. And it also modifies the living organisms like Plants, Animals, and Microorganisms. In recent times, Crop biotechnology has been developed its functionality in agriculture and is also one of the main aspects of agriculture biotechnology. Its desired qualities are exported from a particular species of Crop to an entirely different species. How is Agriculture Biotechnology Used? Genetic Engineering: The term is derived from scientific research provides information about how to move genes from one organism to another. This is known as genetic engineering (GE) or genetic modification (GM). Genetic engineering includes the transfer of useful characteristics by inserting DNA of Plants, animal or microorganism from another organism to another. Molecular Diagnostics: Molecular diagnostics significantly detect genes or gene products that are very precise and specific. Molecular diagnostics is the method used in agriculture to more accurately diagnose crop/livestock diseases. Tissue Culture: Tissue culture is the process of regeneration of plants from the disease-free plant. This technique allows reproduction of disease-free planting material for crops. Unified Methods Used for Corp Modification Traditional Breeding: Traditional breeding method has been used for centuries to improve crop quality and quantity. The crossbreeding describes the combination of two compatible species to create a new variety with the desired traits. The crossbreeding can be only utilized within the same or closely related species. Polyploidy: Polyploidy is the method describes which can be induced to modify the number of chromosomes in a crop in order to influence its fertility or size. Through naturally or with the use of chemicals, the number of chromosomes can change. The process results in the fertility changes in modification within the crop. January 2020| 35
  • 38. the productivity of crops, primarily by reducing the costs of production by decreasing the needs for inputs of pesticides. The process is mostly used in crops grown in temperate zones. The application of agricultural biotechnology can improve the quality of life by developing new strains of plants that give higher crops. The crops can be grown in a wider range of environments which give better rotations to conserve natural resources. It also provides more nutritious harvested products that keep much longer in storage and transport, and continue low-cost food supplies to consumers. According to Crop Science, the company with credible authority on the progress and future implications of Agricultural biotechnology states that, “Farming is evolving in the 21st century with the development and use of biotechnology crops. Scientists and agronomists work in the lab and greenhouse to come up with genes that improve crop yield and make corn, soybean, cotton and canola plants more resistant to insects and more tolerant to herbicides, drought, and stress.” The biotechnology and its process is the evidence of the contributions towards rural development around the world. It serves as the source of inspiration for emerging nations to complement existing practices with agricultural biotechnology. January 2020|36
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  • 40. Today, as technology is making advancements, the world is also progressing with an exponential rate. This advancement has also taken the healthcare space to a different dimension. Yet, there are many diseases and disorders that are untouched by emerging technological advancements. Currently, it is estimated that approximately 2.3 million people are living with cancer in India. Approximately 12 lakh new patients get registered per year and 8 lakh deaths occurs in a year. While there are many brilliant minds in the world working towards changing the devastating scenario of current cancer care, very few have been successful in implementing it. One such visionary startup FastSense Diagnostics (FSD) has taken the responsibility to bring the change which the world is looking forward to. The company is led by three dynamic personalities. Dr. Preeti Nigam Joshi is the Founder of FastSense Diagnostics. While Harish Joshi and Dr. Saildendra Mishra are the Co-founders of the company. The reason behind the genesis of FastSense was when Preeti’s mother was diagnosed with pancreatic cancer. Growing with the Company’s Vision It is known that most of the times lives are lost to late diagnosis of diseases when no treatment is possible. At FastSense Diagnostics the primary focus is to develop portable, easy to use, early-stage detection devices and models for complex diseases. It focuses specifically on deep tissue cancers and neonatal sepsis as these are the untouched segments but deeply affecting many lives. Dr. Preeti says, “Our company is driven by the vision of affordable healthcare for all and the ability to develop the indigenous technologies to bring the cost down and take the benefits of scientific advancements to the last man in society.” Revolutionary Products FastSense is targeting to build point of care devices for early detection of fatal diseases, drug delivery systems for deep tissue cancers and AI-based modules for disease prediction. The company majorly focuses on complex diseases segment including cancers (liver, pancreatic, GI tract, oral, lung), neonatal sepsis, Alzheimer’s, etc. Their premium product L-Sens which would be hitting the market soon is a handy device for diagnosis liver cancer (Hepatocellular Carcinoma). The advantage of the system is that it can be used to screen a large population prone to liver cancer. The next product in the line is Sepsis-S for neonatal sepsis. According to Preeti, in an estimate, India alone reported sepsis cases in 17,000/1,00,000 live births and that data itself shows the gravity of the situation. These cases are comparatively high in the rural parts of the country. “Currently, there is no portable detection method available to identify the cases timely and we are filling the gap by our kit “Sepsis-S”. It’s a state- of-the-art minimally invasive device to identify sepsis onset within 72 hrs. Our products are compatible with smartphones so data can be easily transferred to doctors and healthcare providers to get a timely assessment in critical cases like sepsis,” expresses Dr. Preeti. Overcoming the Challenges As a startup, there are many obstacles that a company has to face. The challenges increased when it came to fundraising for FastSense. Being a non-IT startup, all these obstacles seemed more challenging. Nevertheless, the company, through its innovative thinking and goodwill, received funding. Dr. Preeti mentions, “The biggest problem with technology start-ups (in non-IT domains especially in health tech) is fundraising as many times the product development takes a long time from 3-10 years for medical devices to come into the market and to sustain FastSense Diagnostics The Next-Gen Technology for Swift and E cient Care January 2020|38
  • 41. during such long duration is a big challenge. Although government policies are creating a positive environment for start-ups still it’s a long way to solve all problems that startups face.” Recently, FastSense has received the Bio Ignition Grant and NIDHI Prayas award by the Department of Biotechnology – BIRAC, Government of India. Apart from this, the company made a special news appearance in BioVoice under “Special Startup Series: Affordable diagnostic kits for early-stage cancer detection. Creating a Mark on the Society In the current times, it is necessary to develop oneself while taking each other along. Intermixing of different fields of expertise has been proven beneficial. Dr. Preeti herself has a background in biotechnology but she now works in the field of nanotechnology. Preeti mentions, “We believe the future to be bright as our products have got good responses among experts and clinical validation are on and we are confident of hitting the market at earliest. We will continue to strive for developing products that are in sync with our vision of affordable healthcare. We are developing different in-house facilities and gradually working on team building to bring likeminded people under the umbrella of FastSense so that we could sail full throttle to bring new products and technologies for all.” In the forthcoming years, a combination of numerous information technology like AI, ML, 5G, computing efficiency and chemical sciences will help tackle problems that were otherwise not easy to crack to date. It will further be possible to interlink telemedicine, remote surgery, personalized or customized treatment regime. This will ultimately turn the tables around as the medical healthcare will become distinctly affordable. The prime motivation we have is " Detect early Save lives" and our products will bridge the gap between diagnosis and treatment and provide better survival rates ‘‘ ‘‘ Dr. Preeti Nigam Joshi Founder Mr. Harish Joshi Co-founder Sailendra Mishra Co-founder At FastSense, we have I3 (Innovation, Inspire & Integrity) as a common set of values and our team works with full dedication to solve complex health problems to improve lives ‘‘ ‘‘ The Most Innovative Bio TechSolution Providers to Watch in 2019 1 January 2020| 39