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Nutraceuticals
BST6007
ETH, EPJ, ELA
Dr. Sandeep Singh Rana,
Department of Bio Sciences, SBST
19-09-2022 Dr. Sandeep Singh Rana 1
Expected Course Outcomes (as given in
syllabus)
• Find the functional aspect of nutraceuticals compounds.
• Extend the importance of nutraceuticals in relation to health.
• Discuss the various processing methods of nutraceuticals.
• Select various sources of nutraceuticals from plant, animal, microbes,
and marine origin.
• Predict the diverse nutraceutical compounds involved in disease
prevention
• Decide the safety issues, regulatory policies, health claims, and
clinical trials in using nutraceuticals
19-09-2022 Dr. Sandeep Singh Rana 2
Nutraceuticals (Modules)
1. Introduction to nutraceuticals and functional foods
2. Importance of nutraceuticals
3. Extraction, analysis, physiology, processing of nutraceuticals
4. Nutraceuticals of plant and animal origin
5. Microbial and marine nutraceuticals
6. Nutraceuticals in disease prevention
7. Marketing, regulation, health claims and clinical trials
8. Emerging concepts in nutraceuticals
19-09-2022 Dr. Sandeep Singh Rana 3
Assessment of Course
19-09-2022 Dr. Sandeep Singh Rana 4
Assessment
type
Date
Maximum
Marks
Weightage
Quiz 1 Before CAT – I 20 10
Quiz 2 Before CAT–II 20 10
Assignment After CAT – I 20 10
CAT – I
As per the announcement by the University
15
CAT – II 15
FAT 40
Assignment Topic, Assessment Rubrics
• Choose any one topic from the syllabus
• Select three journal articles from the literature (published after 2015; only
original articles and not review papers; impact factor of the articles chosen
should be greater than 1.5)
• Write a report on the methodology adopted, results obtained, critical analysis of
the results and bibliography; the report should also include alternate
methodologies that can be adopted.
• Written report along with the articles referred should be converted into one
single pdf and submitted.
• Plagiarism check will be performed in the Moodle software after your upload.
19-09-2022 Dr. Sandeep Singh Rana 5
Assignment Topic, Assessment Rubrics
19-09-2022 Dr. Sandeep Singh Rana 6
Rubric/ Marks 0-50% 51-100%
Reporting writing Report written was concise and
the information was just copies
Report written was concise and
the information was written
without copying the content
Quantum of work Report size is less than 1500
words
Report size is more than 1500
words
Critical Review of the article
and methodology
Reviewed without insight and
methods suggested but not
compared and evaluated
appropriately.
Conclusion drawn from the
articles with proper justification
and relevant cum feasible
methods were suggested.
Time management Submission within two days of
specified dead line
Submission on or before the
dead line
Plagiarism Check Above 15% Below 15%
Introduction to nutraceuticals and functional
foods
1. Definition, concept of nutraceuticals
2. Classification of nutraceuticals, dietary supplements, fortified foods,
functional foods
3. Scope involved in the industry- Indian and global scenario
19-09-2022 Dr. Sandeep Singh Rana 7
Definition, concept of nutraceuticals
Nutrition + Pharmaceuticals
• Dr Stephen DeFelice coined the term “Nutraceutical” from “Nutrition”
and “Pharmaceutical” in 1989.
• He defined a nutraceutical as a “food, or parts of a food, that
provide medical or health benefits, including the prevention and
treatment of disease”.
Beyond the diet, but before the drugs
19-09-2022 Dr. Sandeep Singh Rana 8
Nutraceutical products
• Aminomine to treat mental depression.
• L-tryptophan + Lithium to treat bipolar disorder.
• Betaine reduces the levels of homocysteine as this amino acid contributes
to heart disease.
• Lecithin (present in soybeans, egg yolk) treats liver disease, gall bladder
disease, reduces memory loss associated with age, Alzheimer’s treatment.
• CoQ10 to treat migraine, heart failure, Parkinson’s, Huntington’s, AML
(Amyotrophic Lateral Sclerosis- Lou Gehrig’s- motor nerve damage).
• Omega-3 Fatty acids (PUFA): to lower triglycerides.
• Chondroitin: helps body to maintain fluid and flexibility in joints.
• Glucosamine: sugar protein to build body cartilage.
19-09-2022 Dr. Sandeep Singh Rana 9
19-09-2022 Dr. Sandeep Singh Rana 10
Regulatory Control
• New medicines are harder to find and more expensive and risky to
develop than ever before, many companies, for example, Du Pont,
Abbott Laboratories and Warner Lambert, which have produced
conventional pharmaceuticals in the past are now merging to
survive, or are turning to nutraceuticals
• To bring a medicine to market can take about 10 years and cost
$250m whereas to market an unlicensed nutraceutical can take a
fraction of time and the cost.
• Food labelling regulations do not allow food labels to carry health
claims in many countries. This makes it hard for companies
marketing nutraceuticals to advertise the benefits of their products
without a medicine licence.
19-09-2022 Dr. Sandeep Singh Rana 11

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Nutraceutical

  • 1. Nutraceuticals BST6007 ETH, EPJ, ELA Dr. Sandeep Singh Rana, Department of Bio Sciences, SBST 19-09-2022 Dr. Sandeep Singh Rana 1
  • 2. Expected Course Outcomes (as given in syllabus) • Find the functional aspect of nutraceuticals compounds. • Extend the importance of nutraceuticals in relation to health. • Discuss the various processing methods of nutraceuticals. • Select various sources of nutraceuticals from plant, animal, microbes, and marine origin. • Predict the diverse nutraceutical compounds involved in disease prevention • Decide the safety issues, regulatory policies, health claims, and clinical trials in using nutraceuticals 19-09-2022 Dr. Sandeep Singh Rana 2
  • 3. Nutraceuticals (Modules) 1. Introduction to nutraceuticals and functional foods 2. Importance of nutraceuticals 3. Extraction, analysis, physiology, processing of nutraceuticals 4. Nutraceuticals of plant and animal origin 5. Microbial and marine nutraceuticals 6. Nutraceuticals in disease prevention 7. Marketing, regulation, health claims and clinical trials 8. Emerging concepts in nutraceuticals 19-09-2022 Dr. Sandeep Singh Rana 3
  • 4. Assessment of Course 19-09-2022 Dr. Sandeep Singh Rana 4 Assessment type Date Maximum Marks Weightage Quiz 1 Before CAT – I 20 10 Quiz 2 Before CAT–II 20 10 Assignment After CAT – I 20 10 CAT – I As per the announcement by the University 15 CAT – II 15 FAT 40
  • 5. Assignment Topic, Assessment Rubrics • Choose any one topic from the syllabus • Select three journal articles from the literature (published after 2015; only original articles and not review papers; impact factor of the articles chosen should be greater than 1.5) • Write a report on the methodology adopted, results obtained, critical analysis of the results and bibliography; the report should also include alternate methodologies that can be adopted. • Written report along with the articles referred should be converted into one single pdf and submitted. • Plagiarism check will be performed in the Moodle software after your upload. 19-09-2022 Dr. Sandeep Singh Rana 5
  • 6. Assignment Topic, Assessment Rubrics 19-09-2022 Dr. Sandeep Singh Rana 6 Rubric/ Marks 0-50% 51-100% Reporting writing Report written was concise and the information was just copies Report written was concise and the information was written without copying the content Quantum of work Report size is less than 1500 words Report size is more than 1500 words Critical Review of the article and methodology Reviewed without insight and methods suggested but not compared and evaluated appropriately. Conclusion drawn from the articles with proper justification and relevant cum feasible methods were suggested. Time management Submission within two days of specified dead line Submission on or before the dead line Plagiarism Check Above 15% Below 15%
  • 7. Introduction to nutraceuticals and functional foods 1. Definition, concept of nutraceuticals 2. Classification of nutraceuticals, dietary supplements, fortified foods, functional foods 3. Scope involved in the industry- Indian and global scenario 19-09-2022 Dr. Sandeep Singh Rana 7
  • 8. Definition, concept of nutraceuticals Nutrition + Pharmaceuticals • Dr Stephen DeFelice coined the term “Nutraceutical” from “Nutrition” and “Pharmaceutical” in 1989. • He defined a nutraceutical as a “food, or parts of a food, that provide medical or health benefits, including the prevention and treatment of disease”. Beyond the diet, but before the drugs 19-09-2022 Dr. Sandeep Singh Rana 8
  • 9. Nutraceutical products • Aminomine to treat mental depression. • L-tryptophan + Lithium to treat bipolar disorder. • Betaine reduces the levels of homocysteine as this amino acid contributes to heart disease. • Lecithin (present in soybeans, egg yolk) treats liver disease, gall bladder disease, reduces memory loss associated with age, Alzheimer’s treatment. • CoQ10 to treat migraine, heart failure, Parkinson’s, Huntington’s, AML (Amyotrophic Lateral Sclerosis- Lou Gehrig’s- motor nerve damage). • Omega-3 Fatty acids (PUFA): to lower triglycerides. • Chondroitin: helps body to maintain fluid and flexibility in joints. • Glucosamine: sugar protein to build body cartilage. 19-09-2022 Dr. Sandeep Singh Rana 9
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  • 11. Regulatory Control • New medicines are harder to find and more expensive and risky to develop than ever before, many companies, for example, Du Pont, Abbott Laboratories and Warner Lambert, which have produced conventional pharmaceuticals in the past are now merging to survive, or are turning to nutraceuticals • To bring a medicine to market can take about 10 years and cost $250m whereas to market an unlicensed nutraceutical can take a fraction of time and the cost. • Food labelling regulations do not allow food labels to carry health claims in many countries. This makes it hard for companies marketing nutraceuticals to advertise the benefits of their products without a medicine licence. 19-09-2022 Dr. Sandeep Singh Rana 11