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OUR BIOLOGICAL
CLOCK
Samikshya Chhetri
Department of Pharmacy
Kathmandu University
Dhulikhel-04,Kavre,Nepal
www.pharmacyhighlights.com
 The general thinking of the individual is
the time on the clock controls every
aspects and how we live our life. But in
fact, a biological clock is ticking off inside
us that takes the control of our body
functions and behavior.
 Whatever the work we perform, our body
functions like heartbeat and our
hormones and so on, all are being
regulated by the biological clock so-
called circadian clock. www.pharmacyhighlights.com
 Most of the researchers think that if the
medicines were medicated as per the biological
clock, it would be more effective and safer than
according to the clock on our walls. But there are
a lot of challenges to bring it in practice.
 The challenges are two-fold.
 First one is that it is more expensive and time
consuming and the second one is that it is
always easy and not practical to tell which
therapies would benefit most from optically timed
administration.
 There are various tests that should be carried out
like the gold- standard test, the dim light
melatonin onset assay and many more.
www.pharmacyhighlights.com
According to the latest estimates, on a
roughly 24-hr schedule the expression
of half of the genome is controlled by
the biological clock. In this aspect,
knowing the chronotype of the individual
is very useful as it helps to know how
the medicines affect and work inside our
body.
www.pharmacyhighlights.com
www.pharmacyhighlights.com
 The tests are carried out taking the samples from
people with different chronotype and this
algorithm works differently on different people.
 And the goal is to emerge with a blood test that
makes easy to figure out our own genetic
chronotype. The database appeared to code for
the proteins that involved in transport,
metabolism and activity of known drugs.
 The database answers the question like best
time to deliver treatments, gives genetic
expression and also results in even more
therapeutic precision.
In future the researchers can use them to
deconstruct the body’s circadian rhythms into what
Wright calls satellite clocks
www.pharmacyhighlights.com
For detail study visit our site
www.pharmacyhighlights.com.
Thank you!!!
www.pharmacyhighlights.com

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Biological clock

  • 1. OUR BIOLOGICAL CLOCK Samikshya Chhetri Department of Pharmacy Kathmandu University Dhulikhel-04,Kavre,Nepal www.pharmacyhighlights.com
  • 2.  The general thinking of the individual is the time on the clock controls every aspects and how we live our life. But in fact, a biological clock is ticking off inside us that takes the control of our body functions and behavior.  Whatever the work we perform, our body functions like heartbeat and our hormones and so on, all are being regulated by the biological clock so- called circadian clock. www.pharmacyhighlights.com
  • 3.  Most of the researchers think that if the medicines were medicated as per the biological clock, it would be more effective and safer than according to the clock on our walls. But there are a lot of challenges to bring it in practice.  The challenges are two-fold.  First one is that it is more expensive and time consuming and the second one is that it is always easy and not practical to tell which therapies would benefit most from optically timed administration.  There are various tests that should be carried out like the gold- standard test, the dim light melatonin onset assay and many more. www.pharmacyhighlights.com
  • 4. According to the latest estimates, on a roughly 24-hr schedule the expression of half of the genome is controlled by the biological clock. In this aspect, knowing the chronotype of the individual is very useful as it helps to know how the medicines affect and work inside our body. www.pharmacyhighlights.com
  • 6.  The tests are carried out taking the samples from people with different chronotype and this algorithm works differently on different people.  And the goal is to emerge with a blood test that makes easy to figure out our own genetic chronotype. The database appeared to code for the proteins that involved in transport, metabolism and activity of known drugs.  The database answers the question like best time to deliver treatments, gives genetic expression and also results in even more therapeutic precision. In future the researchers can use them to deconstruct the body’s circadian rhythms into what Wright calls satellite clocks www.pharmacyhighlights.com
  • 7. For detail study visit our site www.pharmacyhighlights.com. Thank you!!! www.pharmacyhighlights.com