a de novo mutation in the CACNAID gene cause autism spectrum disorder and epilepsy. this gene codes for a Ca2+ channel that function as a monomer. at the molecular level, the mutation is a missense mutation in the channel protein that causes increased Ca2+ entry into the cell compared to the wild type channels. .

1. a de novo mutation in the CACNAID gene cause autism spectrum disorder and epilepsy.
this gene codes for a Ca2+ channel that function as a monomer. at the molecular level,
the mutation is a missense mutation in the channel protein that causes increased Ca2+
entry into the cell compared to the wild type channels.