2. New heart attack drug may be on the horizon
• Scientists, including one of Indian-origin, have found that some
scarforming cells in the heart can turn to blood vessels and help in
healing the damaged organ, a finding that paves the way for a new
strategy to treat heart attack.
• Researchers from the University of California, Los Angeles, have
discovered that the scar-forming cells in the heart, known as
fibroblasts, have the ability to become endothelial cells -the cells
that form blood vessels to heal an injured heart. In studies
involving mice, the team also found that a drug could enhance this
phenomenon and improve the repair process after a heart attack.
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3. Cont.….
• “It is well known that increasing the number of blood vessels in the
injured heart following a heart attack improves its ability to heal,“ said Dr.
Arjun Deb, the study's senior author and an associate professor of
medicine in the division of cardiology at the David Geffen School of
Medicine at UCLA. “And we know that scar tissue in the heart is associated
with a poorer prognosis. There is compelling clinical evidence to show that
if you have more scar tissue in your heart, you are worse off,“ Deb said.
• “Our findings suggest the possibility of coaxing scarforming cells in the
heart to change their identity into blood vessel-forming cells, which could
potentially be a useful approach for better heart repair,“ he said.
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