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Dr. Md Noor Alam Khan
Dept. of Paediatrics
Dept. of Paediatrics
&
Dept. of Microbiology
Neonatal Sepsis
 Clinical Syndrome characterised by signs and
symptoms of infection with or without
accompanying bacteraemia
Neonatal
Sepsis
Mother’s Birth
canal
Across Placenta
Environment
With health
care facility
Care-related risk factors that
increase the risk of infection
•Intensive care stay
•Presence of invasive medical devices
•Parenteral nutrition
•Antimicrobial therapy which may lead to multiple
drug resistance organism (MDRO) infections
•Overcrowding and Understaffing
•Ward layout (sinks, bed spacing)
•Use of fetal scalp electrodes/ probes and canula
•Contact with colonized/ infected family, visitors, or
healthcare workers
•Proximity of colonized neonates.
•Increased length of stay
Prevent Entry of Microbes Into the
NICU
Infection Control Step I
A- Clean Immediate Environment
Prevent by 5C’s-
 Clean hand
 Clean delivery surface
 Clean cloth
 Clean cord cutting
 Clean cord Clamp
B-Standardize the NICU care
1-Location of NICU-
 Distinct area with controlled access
 Minimum 120 Sq ft clear floor space/baby
 Minimum 4 ft gap between 2 infant beds
2-Airborne infection prevention –
 An airborne infection isolation room
 Hand fee hand washing station
 Area for gowning
 Negative pressure ventilation
 Relative humidity 30-60%
 ACH 6 for NICU, 12 for isolation room
3-Hand washing station–
 Infant bed within 20 feet of HWS
 Free from splash
 Pictorial hand washing instructions
 Space for soap and towel dispensers
C-Hand hygiene
D-Use of Alcohol Based Hand
Rubs
E- Visitors’ policy/ Mobile
restriction
F-Gowning
G-Jewellery & Accessories
Policy
Prevent Proliferation of Microbe in the
NICU
Infection Control Step II
 Dry and clean NICU
 Good house keeping routines
 Daily routine cleaning
 Weekly routine cleaning
 Proper waste disposal
Preventing infection Spread from
Proliferation Sites to baby and From
one baby to another
Infection Control Step III
A- Nurse to Patient Ratio
1:1- Baby on
Ventilator, Critically
ill, MDR resistant
sepsis
1:2-3, Non
ventilated ,
relatively stable
baby
B-Use Disposables
C-Laminar Flow System For Drugs,
Fluids and TPN preparation
Prevent Entry Of Microbe Into The Baby
Infection Control Step IV
 Cord care
 Skin Care
 Aseptic precaution during procedures
Breast milk/Breastfeeding and Correct
Preparation of Formula Milk(when
Indicated)
Infection Control Step V
 Support and promote breastfeeding
 Encourage use of colostrum, trophic feeds and
non nutritive sucking
 If formula milk is needed, ensure adequate
and sterile preparation
Kangaroo Mother Care/ Early
Discharge
Infection Control Step VI
 KMC for LBW and premature baby
 Early step-down, rooming in
 Early discharge
Decreasing Susceptibility of Baby to
Infection
Infection Control Step VII
A-Early Breastfeeding/Use of
Colustrum/Minimal Enteral Nutrition
 B-Immunomodulators: like Probiotics
 C-Antifungal prophylaxis: Recommended for
extremely low birth weight baby
Infection Control Protocols
Infection Control Step VIII
A-Role of Hospital Management
 To provide adequate resources and staff, ward
attendants, housekeeping and other
supportive staff
 Arrangement of necessary equipments
 To establish a multidisciplinary Infection
B-Infection Control Committee
 Yearly programme of activity for surveillance
and prevention
 Epidemiological surveillance data and identify
area of interventions
 Appropriate staff training in infection control
and safety
 Provide inputs into investigation of epidemics
C-Antibiotic Usage and Microbial
Resistance
 Antibiotics policy depending on local
conditions
 Avoid prophylactic antibiotics
 Mandatory blood culture before starting of
antibiotics
 Narrow spectrum antibiotics should be used
 Shorten duration whenever possible
 Restrict Cephalosporin, Carbapenems &
Quinolones to Aminoglycoside and Penecillin
resistant microbes
Conclusion
Infection prevention and control policy in nicu

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Infection prevention and control policy in nicu

Editor's Notes

  1. May be used in between patient examination
  2. Usually microbes enters in nicu through person who enter into nicu. Nicu shold be a cell free zone
  3. Daily- warmer, infusion pump, phototherapy unit, pulse oximeter, hood, floor, basin, bag and mask, laryngoscope, stethoscope, thermometer, BP cuff Weekly- fridge, AC, ventilator and cpap circit, procedre trays
  4. To break the jorney of microbes ample disposables are needed.
  5. Promoting clean cord care and reducing harmful cord application Skin care- prevention of skin injury, use of tegaderm, dropore
  6. KMC is associated with significant redction in severe sepsis.
  7. -Hospital must have In caselike birth asphyxia, prematrity, TTNB without exeption a If blood clture is sterile
  8. Mortality and morbidity of neonate can be significantly reduced by instituting strict infection control strategies This can be achieved by cumulative effort of gynecologist, paediatrician, nursing staff, and other workers with the help of microbiologists and hospital administration and infection control committee.