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CELL AND ITS ORGANELLES
CELL
Cells are the smallest units of life. They are a closed system, can self-replicate, and are the building blocks of
our bodies. The cells provide shape, structure, and carries out different types of functions to keep the
entire system active. There are 2 types of cells: eukaryotic cells, cells- that contain a nucleus and Prokaryotic
cells- cells that lack a nucleus, are structured differently. A cell consists of two major regions, the cytoplasm
and the nucleus. The nucleus is surrounded by a nuclear envelope and contains DNA in the form of
chromosomes. The cytoplasm is a fluid matrix that usually surrounds the nucleus and is bound by the outer
membrane of the cell.
Organelles are small structures within the cytoplasm that carry out functions necessary to maintain
homeostasis in the cell. They are involved in many processes, for example energy production, building
proteins and secretions, destroying toxins, and responding to external signals. Organelles are considered
either membranous or non-membranous. Membranous organelles possess their own plasma membrane to
create a lumen separate from the cytoplasm. This may be the location of hormone synthesis or degradation of
macromolecules. Non-membranous organelles are not surrounded by a plasma membrane. Most non-
membranous organelles are part of the cytoskeleton, the major support structure of the cell. These include:
filaments, microtubules, and centrioles.
Organelles without membrane: The Cell wall, Ribosomes, Microtubules, Actin filaments, Intermediate
filaments, Centrioles and Cytoskeleton are membrane-bound cell organelles. They are present both
in prokaryotic cell and the eukaryotic cell.
Single membrane-bound organelles: Vacuole, Peroxisomes, Lysosome, Golgi apparatus, Endoplasmic
Reticulum are single membrane-bound organelles present only in a eukaryotic cell.
Double membrane-bound organelles: Mitochondria, Vesicles and chloroplast are double membrane-
bound organelles present only in a eukaryotic cell.
CELL
ORGANELLES
STRUCTURE FUNCTIONS
CELL MEMBRANE/
PLASMA
MEMBRANE/
PLASMALEMMA
A double membrane composed of lipids
(cholesterol) and proteins [Phospholipid- lipid-
Phospholipid]. Present both in plant and animal
cell.
Provides shape, protects the
inner organelle of the cell
and acts as a selectively
permeable membrane.
CELL WALL
The cell wall is made up of cellulose,
hemicellulose, and proteins while in a fungal
cell, it is composed of chitin.
protecting and maintaining
the shape of the cell, helps
the cell withstand the turgor
pressure of the cell, initiates
cell division
CENTRIOLE
Cylindrical structure made with nine triplets
microtubules that surround the periphery of the
centriole while the center has a Y-shaped linker
and a barrel-like structure that stabilizes the
centriole.
Cartwheel is present in a centriole which is
made up of a central hub with nine
spokes/filaments radiating from it. Each of these
filaments/spokes is connected to the
microtubules through a pinhead.
forming spindle fibers,
formation of cilia and
flagella
CILIA AND
FLAGELLA
tiny hair-like projections from the cell made of
microtubules and covered by the plasma
membrane. Flagella are a filamentous organelle,
the structure of which is different in prokaryotes
and eukaryotes.
In prokaryotes, flagellin protein is wrapped
C/F- movement of the
organisms & movement of
various particles present
around the organisms.
C- In the blood vessels,
which helps in controlling
around in a helical manner creating a hollow
structure at the center throughout the length.
In eukaryotes, protein is absent and the structure
is replaced with microtubules.
the flow of blood
CENTROSOMES
Composed of Centrioles and found only in the
animal cells.
It plays a major role in
organizing the microtubule
and Cell division.
CYTOPLASM
A jelly-like substance, which consists of water,
dissolved nutrients and waste products of the
cell.
Responsible for the cellโ€™s
metabolic activities.
CYTOSKELETON
A number of fibrous structures are present in the
cytosol that helps give shape to the cell while
supporting cellular transport.
Around three different classes of fibers make up
the cytoskeleton which is: microtubules,
microfilaments, and intermediate filaments.
These are separated based on a protein present
in them.
provide shape and
mechanical support to the
cell against deformation,
expansion and contraction of
the cell, intracellular and
extracellular transport of
materials.
MICROFILAMENTS
thinnest part of the cytoskeleton, and are made
of actin
Useful protein in cell
movement. In the heart,
contraction is mediated
through an actin-myosin
system.
MICROTUBULES
small tubes made from the protein tubulin,
found in cilia and flagella
cell movement, provide
pathways for secretory
vesicles, cell division part
INTERMEDIATE
FILAMENTS
Smaller than the microtubules, but larger than
the microfilaments, they are made of a variety
of proteins such as keratin and/or neurofilament.
They are very stable, and
help provide structure to the
nuclear envelope and anchor
organelles.
ENDOPLASMIC
RETICULUM [ER]
A network of membranous tubules, present
within the cytoplasm of a cell.
Forms the skeletal
framework of the cell,
involved in the
Detoxification, production of
Lipids and proteins.
ROUGH ER
The outer plasma membrane of rER is carpeted
with ribosomes, causing it to appear dotted under
a microscope, composed of cisternae, tubules,
and vesicles.
Protein production; in
particular for export out of
the cell
SMOOTH ER It lacks ribosomes and thus appears smooth under
a microscope and a storage organelle
Lipid & steroid production;
Detoxification
ENDOSOMES
Membrane-bound compartments within a cell
originating from the Golgi network and are
mainly composed of tubular structures.
Allow the sorting and
delivery of internalized
materials from the cell
surface and transport of
materials to the Golgi or the
lysosomes.
GOLGI
APPARATUS/
COMPLEX/ BODY
Membrane-bound, sac-like organelles, present
within the cytoplasm of the eukaryotic cells.
It is mainly involved in
secretion and intracellular
transport.
LYSOSOMES
A tiny, circular-shaped, single membrane-bound
organelles, filled with digestive enzymes.
Helps in the digestion and
removes wastes and digests
dead and damaged cells.
Therefore, it is also called as
the โ€œsuicidal bagsโ€.
Irregular or pleomorphic; are surrounded by a plasma membrane repair, cell
LYSOZYME lysosomal membrane that contains the enzymes
within the lysosome and protects the cytosol
with the rest of the cell from the harmful action
of the enzymes.
signalling, and energy
metabolism
MICROVILLI
tiny finger-like structures that project on or out
of the cells. These exist either on their own or in
conjunction with villi.
increase the surface area of
the cell, allow the breakdown
of larger molecules into
smaller, act as an anchoring
agent in white blood cells
and in sperms during
fertilization
MITOCHONDRIA
An oval-shaped, membrane-bound organelle,
also called as the โ€œPower House of The Cellโ€.
The main sites of cellular
respiration and also involved
in storing energy in the form
of ATP molecules.
NUCLEUS
A largest, double membrane-bound organelles,
which contains the entire cellโ€™s genetic
information.
Controls the activity of the
cell, helps in cell division
and controls the hereditary
characters.
NUCLEOID
Nucleoid is a non-membrane, irregular shaped
cell organelle present in all prokaryotic cells.
They are the carrier of the
genetic material of a cell.
NUCLEOLUS
Within the nucleus is a small subspace known
as the nucleolus. It is not bound by a membrane,
so it is not an organelle.
responsible for making
proteins, assembling and exit
of Ribosomes
PEROXISOME
A membrane-bound cellular organelle present in
the cytoplasm, which contains the reducing
enzyme.
Involved in the metabolism
of lipids and catabolism of
long-chain fatty acids.
PLASMODESMATA
Tiny passages or channels that allow the transfer
of material and communication between
different cells.
Primary site for the
communication of two cells.
It allows the transfer of
molecules like proteins,
RNA, and viral genomes.
PLASTIDS
Double membrane-bound organelles. There are
3 types of plastids:
1.Leucoplast โ€“Colourless plastids.
2.Chromoplastโ€“Blue, Red, and Yellow colour
plastids.
3.Chloroplast โ€“ Green coloured plastids.
Helps in the process of
photosynthesis and
pollination, Imparts colour
for leaves, flowers and fruits
and stores starch, proteins
and fats.
CHLOROPLASTS
Present only in plant cells and contains a green-
coloured pigment known as chlorophyll.
Sites of photosynthesis.
CHROMOPLASTS
Present in certain photosynthetic eukaryotes. production and storage of
carotenoid pigments -
absorbing light energy &
protecting chlorophyll
GERONTOPLASTS
develops from the chloroplast
during senescence in foliage plants
salvaging nutrients and other
important material as a cell
dies
LEUCOPLAST
unpigmented organelles storage of starch
(amyloplasts), lipids
(elaioplasts) and proteins
(proteinoplasts)
RIBOSOMES
Non-membrane organelles, found floating freely
in the cellโ€™s cytoplasm or embedded within the
Involved in the Synthesis of
Proteins.
endoplasmic reticulum.
STORAGE
GRANULES
Membrane-bound organelles, also called
zymogen granules storing cellโ€™s energy reserve
and other metabolites & surrounded by a lipid
bilayer and are composed mostly of phosphorus
and oxygen.
Many prokaryotes and
eukaryotes store nutrients
Sulfur granules are
characteristic of prokaryotes
that utilize hydrogen sulfide
as a source of energy.
VACUOLES
A membrane-bound, fluid-filled organelle found
within the cytoplasm.
Provide shape and rigidity to
the plant cell and helps in
digestion, excretion, and
storage of substances.
VESICLES
Present inside the cell which are either formed
naturally during processes like exocytosis,
endocytosis or transport of materials throughout
the cell, or they might form artificially, which
are called liposomes. It contain liquid or cytosol
which is enclosed by a lipid bilayer
facilitate the storage and
transport of materials in and
outside the cell, exchange of
molecules between two cells,
allow temporary storage of
food and control the
buoyancy of the cell.
Actin - a highly-conserved protein that is actually the most abundant protein in most eukaryotic cells. It is
both flexible and strong.
Cytosol - the proteins that enter the Golgi by mistake are sent back into the cytosol (imagine the barcode
scanning wrong and the item being returned).
Plasma membrane
The plasma membrane surrounds the cell to create a barrier between the cytosol and the extracellular matrix.
Plasma membranes also enclose lumens of some cellular organelles. The structure of the membrane
resembles a fluid mosaic made up of phospholipids, cholesterol, and membrane proteins. Phospholipid
molecules, the main structural components of the membrane, form an amphipathic bilayer.
An amphipathic structure is both hydrophilic and hydrophobic; part of the structure has a high affinity for
water and the other part is repelled by water. The inner surface of each layer is made up of lipid chains and
thus is hydrophobic. The outer surface of each layer is made up of the polar heads of the phospholipids and
is hydrophilic.
Proteins associated with the plasma membrane are either peripheral membrane proteins or integral membrane
proteins. Peripheral membrane proteins interact closely with the membrane through ionic
interactions. Integral membrane proteins are embedded within or pass through the lipid bilayer. There are six
broad categories of integral membrane proteins: pumps, channels, receptors, linkers, enzymes, and structural
proteins.
๏‚ท Pumps - transport ions, sugars, and amino acids across membranes
๏‚ท Channels - allow small ions and molecules to pass freely in and out of the cell
๏‚ท Receptors - recognise and bind with ligands
๏‚ท Linkers - anchor the cytoskeleton to the extracellular matrix
๏‚ท Enzymes - have many roles, for example ATPases participate in ion pumping
๏‚ท Structural proteins - form junctions with neighboring cells
Cell and its Organelle
Cell and its Organelle

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Cell and its Organelle

  • 1. CELL AND ITS ORGANELLES CELL Cells are the smallest units of life. They are a closed system, can self-replicate, and are the building blocks of our bodies. The cells provide shape, structure, and carries out different types of functions to keep the entire system active. There are 2 types of cells: eukaryotic cells, cells- that contain a nucleus and Prokaryotic cells- cells that lack a nucleus, are structured differently. A cell consists of two major regions, the cytoplasm and the nucleus. The nucleus is surrounded by a nuclear envelope and contains DNA in the form of chromosomes. The cytoplasm is a fluid matrix that usually surrounds the nucleus and is bound by the outer membrane of the cell. Organelles are small structures within the cytoplasm that carry out functions necessary to maintain homeostasis in the cell. They are involved in many processes, for example energy production, building proteins and secretions, destroying toxins, and responding to external signals. Organelles are considered either membranous or non-membranous. Membranous organelles possess their own plasma membrane to create a lumen separate from the cytoplasm. This may be the location of hormone synthesis or degradation of macromolecules. Non-membranous organelles are not surrounded by a plasma membrane. Most non- membranous organelles are part of the cytoskeleton, the major support structure of the cell. These include: filaments, microtubules, and centrioles. Organelles without membrane: The Cell wall, Ribosomes, Microtubules, Actin filaments, Intermediate filaments, Centrioles and Cytoskeleton are membrane-bound cell organelles. They are present both in prokaryotic cell and the eukaryotic cell. Single membrane-bound organelles: Vacuole, Peroxisomes, Lysosome, Golgi apparatus, Endoplasmic Reticulum are single membrane-bound organelles present only in a eukaryotic cell. Double membrane-bound organelles: Mitochondria, Vesicles and chloroplast are double membrane- bound organelles present only in a eukaryotic cell. CELL ORGANELLES STRUCTURE FUNCTIONS CELL MEMBRANE/ PLASMA MEMBRANE/ PLASMALEMMA A double membrane composed of lipids (cholesterol) and proteins [Phospholipid- lipid- Phospholipid]. Present both in plant and animal cell. Provides shape, protects the inner organelle of the cell and acts as a selectively permeable membrane. CELL WALL The cell wall is made up of cellulose, hemicellulose, and proteins while in a fungal cell, it is composed of chitin. protecting and maintaining the shape of the cell, helps the cell withstand the turgor pressure of the cell, initiates cell division CENTRIOLE Cylindrical structure made with nine triplets microtubules that surround the periphery of the centriole while the center has a Y-shaped linker and a barrel-like structure that stabilizes the centriole. Cartwheel is present in a centriole which is made up of a central hub with nine spokes/filaments radiating from it. Each of these filaments/spokes is connected to the microtubules through a pinhead. forming spindle fibers, formation of cilia and flagella CILIA AND FLAGELLA tiny hair-like projections from the cell made of microtubules and covered by the plasma membrane. Flagella are a filamentous organelle, the structure of which is different in prokaryotes and eukaryotes. In prokaryotes, flagellin protein is wrapped C/F- movement of the organisms & movement of various particles present around the organisms. C- In the blood vessels, which helps in controlling
  • 2. around in a helical manner creating a hollow structure at the center throughout the length. In eukaryotes, protein is absent and the structure is replaced with microtubules. the flow of blood CENTROSOMES Composed of Centrioles and found only in the animal cells. It plays a major role in organizing the microtubule and Cell division. CYTOPLASM A jelly-like substance, which consists of water, dissolved nutrients and waste products of the cell. Responsible for the cellโ€™s metabolic activities. CYTOSKELETON A number of fibrous structures are present in the cytosol that helps give shape to the cell while supporting cellular transport. Around three different classes of fibers make up the cytoskeleton which is: microtubules, microfilaments, and intermediate filaments. These are separated based on a protein present in them. provide shape and mechanical support to the cell against deformation, expansion and contraction of the cell, intracellular and extracellular transport of materials. MICROFILAMENTS thinnest part of the cytoskeleton, and are made of actin Useful protein in cell movement. In the heart, contraction is mediated through an actin-myosin system. MICROTUBULES small tubes made from the protein tubulin, found in cilia and flagella cell movement, provide pathways for secretory vesicles, cell division part INTERMEDIATE FILAMENTS Smaller than the microtubules, but larger than the microfilaments, they are made of a variety of proteins such as keratin and/or neurofilament. They are very stable, and help provide structure to the nuclear envelope and anchor organelles. ENDOPLASMIC RETICULUM [ER] A network of membranous tubules, present within the cytoplasm of a cell. Forms the skeletal framework of the cell, involved in the Detoxification, production of Lipids and proteins. ROUGH ER The outer plasma membrane of rER is carpeted with ribosomes, causing it to appear dotted under a microscope, composed of cisternae, tubules, and vesicles. Protein production; in particular for export out of the cell SMOOTH ER It lacks ribosomes and thus appears smooth under a microscope and a storage organelle Lipid & steroid production; Detoxification ENDOSOMES Membrane-bound compartments within a cell originating from the Golgi network and are mainly composed of tubular structures. Allow the sorting and delivery of internalized materials from the cell surface and transport of materials to the Golgi or the lysosomes. GOLGI APPARATUS/ COMPLEX/ BODY Membrane-bound, sac-like organelles, present within the cytoplasm of the eukaryotic cells. It is mainly involved in secretion and intracellular transport. LYSOSOMES A tiny, circular-shaped, single membrane-bound organelles, filled with digestive enzymes. Helps in the digestion and removes wastes and digests dead and damaged cells. Therefore, it is also called as the โ€œsuicidal bagsโ€. Irregular or pleomorphic; are surrounded by a plasma membrane repair, cell
  • 3. LYSOZYME lysosomal membrane that contains the enzymes within the lysosome and protects the cytosol with the rest of the cell from the harmful action of the enzymes. signalling, and energy metabolism MICROVILLI tiny finger-like structures that project on or out of the cells. These exist either on their own or in conjunction with villi. increase the surface area of the cell, allow the breakdown of larger molecules into smaller, act as an anchoring agent in white blood cells and in sperms during fertilization MITOCHONDRIA An oval-shaped, membrane-bound organelle, also called as the โ€œPower House of The Cellโ€. The main sites of cellular respiration and also involved in storing energy in the form of ATP molecules. NUCLEUS A largest, double membrane-bound organelles, which contains the entire cellโ€™s genetic information. Controls the activity of the cell, helps in cell division and controls the hereditary characters. NUCLEOID Nucleoid is a non-membrane, irregular shaped cell organelle present in all prokaryotic cells. They are the carrier of the genetic material of a cell. NUCLEOLUS Within the nucleus is a small subspace known as the nucleolus. It is not bound by a membrane, so it is not an organelle. responsible for making proteins, assembling and exit of Ribosomes PEROXISOME A membrane-bound cellular organelle present in the cytoplasm, which contains the reducing enzyme. Involved in the metabolism of lipids and catabolism of long-chain fatty acids. PLASMODESMATA Tiny passages or channels that allow the transfer of material and communication between different cells. Primary site for the communication of two cells. It allows the transfer of molecules like proteins, RNA, and viral genomes. PLASTIDS Double membrane-bound organelles. There are 3 types of plastids: 1.Leucoplast โ€“Colourless plastids. 2.Chromoplastโ€“Blue, Red, and Yellow colour plastids. 3.Chloroplast โ€“ Green coloured plastids. Helps in the process of photosynthesis and pollination, Imparts colour for leaves, flowers and fruits and stores starch, proteins and fats. CHLOROPLASTS Present only in plant cells and contains a green- coloured pigment known as chlorophyll. Sites of photosynthesis. CHROMOPLASTS Present in certain photosynthetic eukaryotes. production and storage of carotenoid pigments - absorbing light energy & protecting chlorophyll GERONTOPLASTS develops from the chloroplast during senescence in foliage plants salvaging nutrients and other important material as a cell dies LEUCOPLAST unpigmented organelles storage of starch (amyloplasts), lipids (elaioplasts) and proteins (proteinoplasts) RIBOSOMES Non-membrane organelles, found floating freely in the cellโ€™s cytoplasm or embedded within the Involved in the Synthesis of Proteins.
  • 4. endoplasmic reticulum. STORAGE GRANULES Membrane-bound organelles, also called zymogen granules storing cellโ€™s energy reserve and other metabolites & surrounded by a lipid bilayer and are composed mostly of phosphorus and oxygen. Many prokaryotes and eukaryotes store nutrients Sulfur granules are characteristic of prokaryotes that utilize hydrogen sulfide as a source of energy. VACUOLES A membrane-bound, fluid-filled organelle found within the cytoplasm. Provide shape and rigidity to the plant cell and helps in digestion, excretion, and storage of substances. VESICLES Present inside the cell which are either formed naturally during processes like exocytosis, endocytosis or transport of materials throughout the cell, or they might form artificially, which are called liposomes. It contain liquid or cytosol which is enclosed by a lipid bilayer facilitate the storage and transport of materials in and outside the cell, exchange of molecules between two cells, allow temporary storage of food and control the buoyancy of the cell. Actin - a highly-conserved protein that is actually the most abundant protein in most eukaryotic cells. It is both flexible and strong. Cytosol - the proteins that enter the Golgi by mistake are sent back into the cytosol (imagine the barcode scanning wrong and the item being returned). Plasma membrane The plasma membrane surrounds the cell to create a barrier between the cytosol and the extracellular matrix. Plasma membranes also enclose lumens of some cellular organelles. The structure of the membrane resembles a fluid mosaic made up of phospholipids, cholesterol, and membrane proteins. Phospholipid molecules, the main structural components of the membrane, form an amphipathic bilayer. An amphipathic structure is both hydrophilic and hydrophobic; part of the structure has a high affinity for water and the other part is repelled by water. The inner surface of each layer is made up of lipid chains and thus is hydrophobic. The outer surface of each layer is made up of the polar heads of the phospholipids and is hydrophilic. Proteins associated with the plasma membrane are either peripheral membrane proteins or integral membrane proteins. Peripheral membrane proteins interact closely with the membrane through ionic interactions. Integral membrane proteins are embedded within or pass through the lipid bilayer. There are six broad categories of integral membrane proteins: pumps, channels, receptors, linkers, enzymes, and structural proteins. ๏‚ท Pumps - transport ions, sugars, and amino acids across membranes ๏‚ท Channels - allow small ions and molecules to pass freely in and out of the cell ๏‚ท Receptors - recognise and bind with ligands ๏‚ท Linkers - anchor the cytoskeleton to the extracellular matrix ๏‚ท Enzymes - have many roles, for example ATPases participate in ion pumping ๏‚ท Structural proteins - form junctions with neighboring cells