The document discusses the histology of the pancreas, describing its exocrine and endocrine components. The exocrine portion contains acinar cells that secrete approximately 1500 mL of pancreatic juice per day into the duodenum through ducts, containing enzymes that break down proteins, nucleic acids, carbohydrates, lipids, and cholesterol. The endocrine portion is made up of clusters of cells called the islets of Langerhans that secrete important hormones like insulin and glucagon which regulate carbohydrate metabolism.

1. Universidad de Ciencias y Artes de Chiapas
Facultad de Ciencias Odontológicas y Salud Publica
Licenciatura en Cirujano Dentista
Asignatura:
Fisiología
Contenido:
Aparato Digestivo: Páncreas
Docente:
Dra. Maria Georgina Rivas Bocanegra
EQUIPO 4
Integrantes:
Aguirre Alfonso Magda Karina
Córdova Esteban Diana Minelli
Diaz Carreño Nadelyn
Dominguez Gallegos Montserrat
Hidalgo Morales Esmirna
Grado: 2 Grupo: “A”

2. Histología del Páncreas
El páncreas está formado por dos componentes secretorios: el tejido insular o endocrino (islotes
de Langerhans) y el tejido acinar o exocrino.
La porción exocrina contiene células acinosas que sintetizan unos 1500 mL de jugo pancreático
por día que se vacían en el duodeno a través del sistema de conductos excretores.
El jugo pancreático contiene varias enzimas
capaces de degradar los componentes
principales del alimento, además de
abundantes iones bicarbonato que
desempeñan un papel esencial en la
neutralización del quimo gástrico ácido.

3. Las enzimas son secretadas sólo por las células acinosas.
• Tripsina, quimotripsina y carboxipeptidasas: degradan las proteínas no digeridas o
digeridas en parte a péptidos pequeños o aminoácidos libres.
• RibonucIeasa y la desoxirribonucIeasa: escinden las correspondientes nucleoproteínas.
• Amilasa pancreática: hidroliza almidón, glucógeno y la mayor parte de los demás
hidratos de carbono (pero no celulosa) a disacáridos.
• Lipasa pancreática: hidroliza los triacilgliceroles a monoacilglicerol y ácidos grasos libres,
mientras que la colesterol esterasa escinde los ésteres de colesterol.
La porción endocrina se compone de las células de los islotes de Langerhans que producen,
por ejemplo, las hormonas insulina y glucagón, de importancia fundamental sobre el
metabolismo de los hidratos de carbono. Estas hormonas son liberadas al torrente sanguíneo.
Las células A (células alfa) secretan glucagón y representan
cerca del 20% de las células; las células B (células beta)
secretan insulina y representan alrededor del 70% de las
células; las células D (células delta) secretan somatostatina y
representan el 5-10% de las células y las células F secretan
polipéptido pancreático y representan el 1-2% de las células

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