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Approach to Obstructive
Jaundice
Udit Mishra
Surgery Resident
Outline
• History
• Examination
• Investigations
• Treatment
History
• Is it jaundice or not
• Obstructive vs Hemolytic jaundice
• Causes that led to jaundice
• Condition/status of the patient
• Complications
Jaundice
• Yellowish pigmentation of sclera or other
mucus membrane due raised bilirubin level in
blood (>2mg/dl)
• Jaundice without any prodormal symptoms is
usually Surgical jaundice
Causes
• Intraluminal
– Primary and secondary CBD stones
– Flukes
• Fasciola
• Ascariasis
• Clonorchis
• Schistosomiasis
– Tumor emboli
• Mural
– Congenital
• Congenital atresia
• Choledochal cyst
– Inflammatory
• Sclerosing cholangitis
– Neoplastic
• Cholangiocarcinoma
– Benign Stricture
• Post traumatic
• Post radiotherapy
• Post inflammatory
• Extra luminal
– Malignant :
• Periampullary carcinoma
• Carcinoma head of pancreas
• Carcinoma gall bladder
• Porta hepatis nodes
– Carcinoma gall bladder
– Carcinoma stomach
– Colorectal malignancy
– Benign :
• Chronic Pancreatitis
• Mirrizi syndrome
History continued
• Age, sex, demography
• Jaundice – onset, progression, duration
• Urine color
• Stool color
• Abdominal pain
• Pruritus
• Anorexia, early satiety, Weight loss
• High grade fever with chills and rigor
• Change in bowel habit
• Alcohol or drug intake
• Previous biliary surgery
• Systemic review
Physical examination
• To know the
– Status of the patient
– Cause
– Complications
• Vital status
• Eyes
• Scratch marks
• Signs of liver cell failure :
• Testicular atrophy
• Gynecomastia
• Vascular spiders
• Dupuytren’s contracture
• Parotid enlargement
• Palmer erythema
• Hepatomegaly
• Palpable gall bladder
• Courvoiser’s law
• Exceptions
• Charcot’s Triad, Reynold’s pentad
• Splenomegaly
Investigations
• To confirm the disease
• To know the cause
• To stage the disease
• To asses the status of patient
• To plan the management
To confirm the disease
• LFT –TB, DB
• Fecal stercobilin, urobilin
To know the cause
• Abdominal ultrasound
• Triphasic CECT abdomen and pelvis
• MRCP/ERCP/PTC
• HIDA scan
• EUS
HIDA scan
To assess the status of Patient
• CBC
• LFT – ALT, AST, ALP, PT/INR, Total and Direct
bilirubin, Total protein, albumin
• RFT, electrolyt4es
• Chest Xray, HRCT chest
Tumor markers
• CA-19-9
• CEA
To plan the management/staging
• PET scan
• Bone scan
• Laparoscopy
• Cardiological assessment
Management
• Preoperative management
– Hydration – D10, D5
– Nutrition – fat soluble vitamins (A,D,E,K)
– Antibiotic prophylaxis – broad spectrum
– Correction of anemia, hypoproteinemia
– Symptomatic relief
• Pruritus- cholestyramine 4g TDS
• Pain- opoids vs non-opoids
– Decompression
Preoperative biliary drainage
• Indications :
– Cholangitis
– Severe pruritus
– Neoadjuvant chemotherapy
– Delayed surgery
– Routine decompression (controversary)
– Right hepatectomy
– Portal vein embolisation
Surgery
• According to cause
• Aim :
– To cure the disease
– To relief symptoms
– To improve quality of life
• Thank you

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Approach to Surgical Jaundice.pptx

  • 1. Approach to Obstructive Jaundice Udit Mishra Surgery Resident
  • 2. Outline • History • Examination • Investigations • Treatment
  • 3. History • Is it jaundice or not • Obstructive vs Hemolytic jaundice • Causes that led to jaundice • Condition/status of the patient • Complications
  • 4. Jaundice • Yellowish pigmentation of sclera or other mucus membrane due raised bilirubin level in blood (>2mg/dl) • Jaundice without any prodormal symptoms is usually Surgical jaundice
  • 5. Causes • Intraluminal – Primary and secondary CBD stones – Flukes • Fasciola • Ascariasis • Clonorchis • Schistosomiasis – Tumor emboli
  • 6. • Mural – Congenital • Congenital atresia • Choledochal cyst – Inflammatory • Sclerosing cholangitis – Neoplastic • Cholangiocarcinoma – Benign Stricture • Post traumatic • Post radiotherapy • Post inflammatory
  • 7. • Extra luminal – Malignant : • Periampullary carcinoma • Carcinoma head of pancreas • Carcinoma gall bladder • Porta hepatis nodes – Carcinoma gall bladder – Carcinoma stomach – Colorectal malignancy – Benign : • Chronic Pancreatitis • Mirrizi syndrome
  • 8. History continued • Age, sex, demography • Jaundice – onset, progression, duration • Urine color • Stool color • Abdominal pain • Pruritus • Anorexia, early satiety, Weight loss • High grade fever with chills and rigor • Change in bowel habit • Alcohol or drug intake • Previous biliary surgery • Systemic review
  • 9. Physical examination • To know the – Status of the patient – Cause – Complications
  • 10. • Vital status • Eyes • Scratch marks • Signs of liver cell failure : • Testicular atrophy • Gynecomastia • Vascular spiders • Dupuytren’s contracture • Parotid enlargement • Palmer erythema • Hepatomegaly • Palpable gall bladder
  • 11. • Courvoiser’s law • Exceptions • Charcot’s Triad, Reynold’s pentad • Splenomegaly
  • 12. Investigations • To confirm the disease • To know the cause • To stage the disease • To asses the status of patient • To plan the management
  • 13. To confirm the disease • LFT –TB, DB • Fecal stercobilin, urobilin
  • 14. To know the cause • Abdominal ultrasound • Triphasic CECT abdomen and pelvis • MRCP/ERCP/PTC • HIDA scan • EUS
  • 15.
  • 16.
  • 17.
  • 18.
  • 19.
  • 20.
  • 21.
  • 22.
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 29. To assess the status of Patient • CBC • LFT – ALT, AST, ALP, PT/INR, Total and Direct bilirubin, Total protein, albumin • RFT, electrolyt4es • Chest Xray, HRCT chest
  • 31. To plan the management/staging • PET scan • Bone scan • Laparoscopy • Cardiological assessment
  • 32.
  • 33. Management • Preoperative management – Hydration – D10, D5 – Nutrition – fat soluble vitamins (A,D,E,K) – Antibiotic prophylaxis – broad spectrum – Correction of anemia, hypoproteinemia – Symptomatic relief • Pruritus- cholestyramine 4g TDS • Pain- opoids vs non-opoids – Decompression
  • 34. Preoperative biliary drainage • Indications : – Cholangitis – Severe pruritus – Neoadjuvant chemotherapy – Delayed surgery – Routine decompression (controversary) – Right hepatectomy – Portal vein embolisation
  • 35. Surgery • According to cause • Aim : – To cure the disease – To relief symptoms – To improve quality of life