Flexible chip for long-term antimicrobial resistance experiments
ListOfInventions_Jiang_Mingyang_InsightPD
1.
217.898.5037 // MingyangJiang2015@u.northwestern.edu // 800 Hinman Ave APT 605 // Evanston, IL, 60202
Mingyang
Jiang
LIST
OF
INVENTIONS
PERSONAL
HIGHLIGHTSMICROWELLSTAMP
www.linkedin.com/in/MingyangJiang
• Enthusiastic
bioengineer,
critical
thinker,
and
innovative
problem
solver
• Effectively
communicating
with
fellow
researchers
to
identify
new
research
needs
• Efficiently
combining
engineering
and
biosciences
to
deliver
creative
solutions
• Excellent
leader,
organizer
and
planner,
yet
good
at
dealing
with
ambiguity
• Enjoy
working
in
multidisciplinary
teams
at
a
self-‐motivated
fast
pace
OViPokeTM
OViPokeTM
is
a
new
tool
designed
for
ovarian
biology
that
helps
researchers
obtain
biologic
material
more
efficiently.
Unlike
current
methods
of
oocyte
isolation
that
utilizes
2
syringe
needles
to
perforate
the
ovary,
the
OViPokeTM
is
a
pen-‐shaped
device
that
allows
the
researcher
to
have
precise
control
over
their
experiment
and
maximum
perforation
in
a
short
period
of
time.
OViPokeTM
has
a
clean
and
simplified
design
for
easy
sterilization
and
improved
durability.
Microwell
Stamp
Embryoid
body
formation
is
a
technique
used
to
differentiate
stem
cells;
stem
cells
tend
to
grow
in
clumps
thus
uniform
distribution
is
very
important
to
avoid
irregular
embryoid
body
shapes.
The
PDMS
microwell
stamp
creates
microwell
structures
(diameter
800µM)
on
an
agarose
base,
allowing
stem
cells
to
form
an
optimally
shaped
embryoid
body
within
the
constraints
of
a
single
microwell.
This
design
eases
researchers
from
pipetting
each
cell
individually,
and
costs
90%
less
than
commercial
products.
a.
3rd
generation
stamp
design;
b.
Surface
of
a
stamp;
c.
Surface
of
stamped
structures
under
microscope;
d.
Embryoid
bodies
in
well
a
b
c
d
OviPokeWELLMODIFICATION
Cell
Culture
Plate
Well
Modification
Zinc
spark
is
a
promising
biomarker
to
determine
the
readiness
of
egg
for
in-‐vitro
fertilization.
The
current
method
uses
a
dye-‐coated
glass
slide
to
capture
zinc,
losing
zinc
signal
due
to
the
2D
nature.
This
well
modification
incorporates
zinc
dye
into
the
agarose
base,
and
creates
a
3D
surrounding
structure
to
capture
more
zinc
signal.
It
also
prevents
the
egg/cell
from
floating
around,
allowing
for
more
stable
imaging
using
an
automated
microscope.
The
end
goal
is
to
develop
a
new
clinical
tool
for
in-‐vitro
fertilization.
OTHER
Rapid
Soil
Nematode
Extraction
This
floating
apparatus
efficiently
extract
the
nematode-‐containing
layer
of
solution
after
soil
flocculation
–
the
1st
step
of
developing
a
hand-‐held
nematode
detector
(left).
Improved
Pearl
Millet
Grain
Processing
Machine
An
insert
that
extends
the
grain
feeder
to
minimize
loss
(right).
Foam