In the growing biopharmaceutical market, diversity and demand of biologics has increased the complexity and vulnerability of global supply chains to disruptions.
Collaboration between biopharmaceutical manufacturers and suppliers is crucial for supply robustness and control. An accurate demand and long-range forecast drive the right supply chain decisions such as capacity investments and expansions, at the right times to enable our combined success.
In this webinar, you will learn about the importance of collaborative forecasting and transparency to product requirements.
In this webinar, you will learn how:
- And when to share an accurate, up-to-date forecast with your suppliers
- The forecast information is used by the supplier to make supply network decisions
- To partner with your supplier to ensure supply robustness
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How to make your supply chain more robust with collaborative forecasting & transparency?
1. Merck KGaA
Darmstadt, Germany
Aida Tsouroukdissian
Head of Demand Planning, Integrated Supply Chain
Operations
21 February 2019
How to make your
supply chain more
robust with
collaborative
forecasting &
transparency?
2. 2
The life science business of
Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma
in the U.S. and Canada.
4. The first rule of forecasting –
that forecasts are always wrong –
is truer today than ever before.
Collaborative Forecasting | 21 February 2019
The Power of Resilience
Yossi Sheffi
5. Demonstrate how collaboration between biopharmaceutical manufacturers and
suppliers is crucial for supply robustness and control.
Learn
How and when to collaborate to mitigate potential supply risk
With whom to partner to have a successful collaboration process
How collaboration adds value
How to measure success of the collaboration process
How To Make Your Supply Chain More Robust with Collaborative Forecasting?
Objective
Collaborative Forecasting | 21 February 2019
7. How To Make Your Supply Chain More Robust with Collaborative Forecasting?
Forecasting Future Biologic Manufacturing Capacity Requirements
Challenges
New Drug Product
Classes
Clinical Trial Results
New Indications
Manufacturing Scale
Bioreactor Size
Titer Projections
Number of Batches
Yield
Shelf-life
Bill of Materials
Patient Demand
Volume
Uptake
Dosage / Frequency of
Administration
Competition
Market Share
Biologic Product Launch
Timing
Approval by Regulatory
Authorities, By Geography
Collaborative Forecasting | 21 February 2019
8. How To Make Your Supply Chain More Robust with Collaborative Forecasting?
Implications of Bill-of-Material Forecasts for Suppliers
Forecast is Too Low
Supplier is unable to
meet customer demand
1. Out of stock
2. Disruptions
3. Allocation
Forecast is Too High
Supplier has too much
capacity
1. Increased cost of goods
2. Negative working capital
3. Increased pricesCollaborative Forecasting | 21 February 2019
9. How To Make Your Supply Chain More Robust with Collaborative Forecasting?
Our Process
Review
Business
Review
Demand
Review
Supply
Sales &
Operations
Planning
(S&OP)
Life Cycle
Management
(LCM)
Capacity
Review
Process Budgeting
OP
Collaborative Forecasting | 21 February 2019
10. How To Make Your Supply Chain More Robust with Collaborative Forecasting?
Long Range Planning Process
Demand
Planning
Monthly
Commercial
Demand
Review
• Commercial
Review
0-18 months
Quarterly
Portfolio
Review
• Business Review
3-5years
Annual
Strategic
Planning
Review
• Business Review
10 years
Semi-
Annual
Long Range
Planning
• Handover to Operations in
COGS/units for Capacity Planning
Assessment in June & November
• Portfolio
Review
➢ Understand upside opportunities
and downside risks
➢ Collaboration process with
customers
ISC
Reviews
➢ Long range demand plan
driving long range capacity
planning
➢ Annual process with twice
a year assessment of global
capacities and actions needed
to mitigate risks
Collaborative Forecasting | 21 February 201910
Monthly/Quarterly
Customer
Collaboration Review
Molecule
Mapping
11. S&OP Connection with Capacity Review Process
Portfolio
review
Demand Plan Phase In/Out & Trends Long Range Plan
Commercial Area
(0-18 months)
Business Area
(0-5 years)
How To Make Your Supply Chain More Robust with Collaborative Forecasting?
Demand Planning Trends
Review
Business
Review
Demand
Review
Supply
Sales &
Operations
Planning
(S&OP)
Capacity
Review
Process
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
S&OP
Portfolio Review
Long Range Plan (LRP)
Collaborative Forecasting | 21 February 2019
12. How To Make Your Supply Chain More Robust With Collaborative Forecasting?
What Do We Do With Your Forecasts?
Resources Global Supply NetworkManufacturing Production
Lines & Sites
Use Information to execute in the short-term and
make long-term Investment Decisions
Collaborative Forecasting | 21 February 2019
13. How To Make Your Supply Chain More Robust with Collaborative Forecasting?
Demand Planning – Your Collaboration Partner
Head of Global
Demand
Planning
Global
Portfolio
Planning
Tools & Data
Management
Commercial
Planning
Global
Strategic
Accounts
Regional
Accounts
Custom
Planning
Portfolio by
Customer
Collaborative Forecasting | 21 February 2019
Global
MKT
OPS
MKT
COMM
Global
DP
Global
COMM
SD
14. Communicate
up-to-date
requirements
monthly
Collaborative Forecasting | 21 February 2019
How To Make Your Supply Chain More Robust with Collaborative Forecasting?
What Can You – As Our Customer – Do?
1
By Manufacturing Site Location:
• Country/Region
2
By Molecule:
• Phase I, II, III
• Commercial
3
By Material:
• Supplier SKU – Identify “critical”
RM’s with Unit of Measure
• Quantity required by month with 12
Month rolling forecast
• Long Range Plan 3-5 years
15. Collaborative Forecasting | 21 February 2019
How To Make Your Supply Chain More Robust with Transparency?
What Can You – As Our Customer – Do?
Share your Confidence Level of the
accuracy of the forecast
Share the Market Outlook for the
molecule based on patient
demographics, competitive information
and more
Highlight changes based on previously
provided forecasts, risks and
opportunities
Share strategic information influencing
the Demand Plan
• Planned inventory strategy changes
• Terminal buys of pre-change inventory
• Risk mitigation activities, such as dual
sourcing
• Large capacity investments
• Brexit, Tariffs, Regulatory
1
2
3
4
Confidence
High
Medium
Low
Legend
Increase On Track Decrease
16. Be more
transparent
Collaborative Forecasting | 21 February 2019
How To Make Your Supply Chain More Robust with Transparency?
What Can We – As Your Supplier – Do?
1
By Product Classification
• Lead Times
• Potential disruptions
2
3
By Forecast
• Trends
• Highlight deviations
By Process
• Provide guidance
• Share best practices
17. Collaborative Forecasting | 21 February 2019
How To Make Your Supply Chain More Robust?
What Do We Do With Your Forecasts?
Actions:
1. Analyze and
confirm forecast
by request date
2. Enter
information into
planning system
3. Hand over to
Operations’
Partners –
Highlight
changes, trends,
risks &
opportunities
4. Drives decisions
Result:
Improved Service Levels
18. Collaborative Forecasting | 21 February 2019
How To Make Your Supply Chain More Robust with Transparency?
Portfolio Segmentation
19. Collaborative Forecasting | 21 February 2019
How To Make Your Supply Chain More Robust with Transparency?
Together, We Can Strengthen Our Supply Chains
1 Realize the Power of Collaboration
2
3
Implement a Supply Chain strategy with
collaboration as a core element between
Planning : Planning teams
Develop mutually agreed KPIs and jointly
improve on-time delivery metrics
& meet patients’ needs for
life-saving & life-enhancing drugs
110
85
95
76
105
100
92
100
95
100
105
94
75%
70%
82%
76%
82% 83% 84% 86% 88% 89% 91%
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
0
20
40
60
80
100
120
# of Lines % OTIF Target
20. Collaborative Forecasting | 21 February 2019
Closing
remarks
"Curiosity is not only about finding
new ideas.
It is about being able to deal with
the new, the complex. It is about
being able and willing to continue
even if the new brings unpleasant
feelings with it.”
Carl Naughton
Linguistic Researcher at the University of Cologne,
Germany
Educational Speaker & Member of the Merck KGaA ,
Darmstadt, Germany Curiosity Council