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VALUE FOCUS
Medtech & Device Industry
Third Quarter 2022
The update includes a review of market performance, valuation multiple trends, operating metrics, and other market data. This issue also includes
a review of M&A and IPO activity during the second quarter of 2022.
Mercer Capital has broad experience in providing valuation services to medtech and device start-ups, larger public and private companies, and
private equity and venture capital funds involved in the sector. Please contact us to discuss how we may be of help.
BUSINESS VALUATION &
FINANCIAL ADVISORY SERVICES
Copyright © 2022 Mercer Capital Management, Inc. All rights reserved. It is illegal under Federal law to reproduce this publication or any portion of its contents without the
publisher’s permission. Media quotations with source attribution are encouraged. Reporters requesting additional information or editorial comment should contact Barbara
Walters Price at 901.685.2120. Mercer Capital’s Industry Focus is published quarterly and does not constitute legal or financial consulting advice. It is offered as an informa-
tion service to our clients and friends. Those interested in specific guidance for legal or accounting matters should seek competent professional advice. Inquiries to discuss
specific valuation matters are welcomed. To add your name to our mailing list to receive this complimentary publication, visit our web site at www.mercercapital.com.
Contact Us
BUSINESS VALUATION &
FINANCIAL ADVISORY SERVICES
Medtech & Device Industry Services
Mercer Capital provides valuation services to start ups, larger public
and private companies, and private equity and venture capital funds.
Contact a Mercer Capital professional to discuss your needs in confidence.
Sujan Rajbhandary, CFA
901.322.9749
sujanr@mercercapital.com
Travis W. Harms, CFA, CPA/ABV
901.322.9760
harmst@mercercapital.com
J. David Smith, ASA, CFA
713.239.1005
smithd@mercercapital.com
Daniel P. McLeod, CFA
901.322.9716
mcleodd@mercercapital.com
J. Davis Rolfe, Jr., CPA
901.322.9712
rolfed@mercercapital.com
Follow Mercer Capital Mercer Capital @MercerCapital
In This Issue
Mercer Capital’s expertise in the medtech and device
industry spans the following segments:
• Biotechnology and life sciences
• Medical devices
• Healthcare technology
• Large, diversified
Our services include:
• Purchase price allocations
• Impairment testing
• Portfolio valuation for LP reporting
• Transaction and valuation advisory
• Equity compensation valuation for tax
compliance
Learn More about Mercer Capital &
our Medtech & Device Services at
www.mercercapital.com
Stock Market Performance	 1
Revenue Multiples	 4
EBITDA Multiples	 5
Select Operating Metrics	 6
Public Medical Device Companies 7
Mergers  Acquisitions 11
Initial Public Offerings 13
© 2022 Mercer Capital // www.mercercapital.com 1
Mercer Capital’s Value Focus: Medtech  Device Industry Third Quarter 2022
The SP 500 declined 16.4% during the second quarter of 2022 as the market downturn that began earlier in the year
gathered pace. As the Fed maintained an aggressive stance to counter inflation by raising interest rates and signaling
further increases, broader market moves reflected the increase in cost of capital. The medtech and device industry did
not remain unscathed by the general trend.
Compared to the prior quarter, estimates of forward earnings and cash flows changed only modestly but implied
valuation multiples compressed meaningfully. Perhaps, (downward) revision of earnings estimates is a lagging feature
that will manifest more noticeably later in the year if worries about the decelerating economy persist. Amid the stock
market turmoil, quarterly and year-to-date MA and IPO deal activity also slowed down compared to the same periods
in the prior year.
While three of four sub-sectors tracked by Mercer Capital outperformed the broader index in terms of stock price
performance, the medical devices group was a notable laggard. The group of large, diversified companies was the only
sub-sector that outperformed SP 500 during the first two quarters of 2022 and the year ended 2022.
• A market-capitalization weighted index of companies included in our biotechnology and life sciences sub-sector
decreased 14.8% over the quarter ended June 2022. The top performer of the group was Vertex Pharmaceuticals,
which posted an 8.0% return. VRTX discovers, develops, and commercializes pharmaceutical products for the
treatment of cystic fibrosis, cancer, inflammatory bowel, autoimmune disease, and neurological disorders.
• The medical device sub-sector index declined 28.0% in 2Q22. The group’s best performer was Olympus which
returned 4.4%. Olympus manufactures optoelectronic products including cameras, video sets, endoscopes for
medicine and industrial use, microscopes, analytical equipment, office communication systems, and laser optical
scanners.
Stock Market
Performance
© 2022 Mercer Capital // www.mercercapital.com 2
Mercer Capital’s Value Focus: Medtech  Device Industry Third Quarter 2022
• The healthcare technology sub-sector decreased 11.2% over the period. HealthStream, rising 9.0%, outperformed
all other constituents of the group. HSTM offers web-based solution to the continuing education and training needs
of the healthcare community including workforce development, training and learning management, credentialing,
privileging, provider enrollment, performance assessment, and managing simulation-based education programs.
• The group of large, diversified companies decreased 8.1% over the quarter. The top performer within the group
was Amgen which increased 1.4% during the period. AMGN is an independent biotechnology company that
discovers, develops, manufactures, and markets medicines for grievous illnesses while focusing on human
therapeutics and concentrating on innovating novel medicines based on cellular and molecular biology.
2Q 2022 Stock Price Performance
-14.8%
-28.0%
-11.2%
-8.1%
-16.4%
-35%
-30%
-25%
-20%
-15%
-10%
-5%
0%
5%
10%
Mar 22 Apr 22 May 22 Jun 22
Biotechnology  Life Sciences Medical Devices Healthcare Technology Large, Diversified SP 500
Stock Market
Performance
(cont.)
Individual sub-sector performance represented by market capitalization weighted indices for each group.
Data Source: Bloomberg LP; Mercer Capital Analysis
© 2022 Mercer Capital // www.mercercapital.com 3
Mercer Capital’s Value Focus: Medtech  Device Industry Third Quarter 2022
Individual sub-sector performance represented by market capitalization weighted indices for each group.
Source: Bloomberg LP; Mercer Capital Analysis
Stock Market
Performance
(cont.)
LTM Stock Price Performance
-14.2%
-32.2%
-40.6%
2.9%
-11.9%
-60%
-50%
-40%
-30%
-20%
-10%
0%
10%
20%
30%
Jun 21 Jul 21 Aug 21 Sep 21 Oct 21 Nov 21 Dec 21 Jan 22 Feb 22 Mar 22 Apr 22 May 22 Jun 22
Biotechnology  Life Sciences Medical Devices Healthcare Technology Large, Diversified SP 500
YTD Stock Price Performance
-22.3%
-36.9%
-27.2%
-10.9%
-20.6%
-45%
-40%
-35%
-30%
-25%
-20%
-15%
-10%
-5%
0%
5%
Dec 21 Jan 22 Feb 22 Mar 22 Apr 22 May 22 Jun 22
Biotechnology  Life Sciences Medical Devices Healthcare Technology Large, Diversified SP 500
© 2022 Mercer Capital // www.mercercapital.com 4
Mercer Capital’s Value Focus: Medtech  Device Industry Third Quarter 2022
4.85x
3.65x
3.98x
4.48x 4.33x 4.09x
4.43x 4.64x
4.23x
4.21x
0.00x
1.00x
2.00x
3.00x
4.00x
5.00x
6.00x
7.00x
8.00x
9.00x
4Q15 1Q16 2Q16 3Q16 4Q16 1Q17 2Q17 3Q17
75% Quartile Median 25% Quartile
Biotechnology  Life Sciences
EV / Trailing LTM Revenue
Healthcare Technology
EV / Trailing LTM Revenue
Medical Devices
EV / Trailing LTM Revenue
Large, Diversified
EV / Trailing LTM Revenue
8.15x
3.19x
2.37x
0x
2x
4x
6x
8x
10x
12x
14x
16x
2Q 2022
1Q 2022
4Q 2021
3Q 2021
2Q 2021
1Q 2021
4Q 2020
3Q 2020
5.69x
4.43x
4.20x
0x
1x
2x
3x
4x
5x
6x
7x
2Q 2022
1Q 2022
4Q 2021
3Q 2021
2Q 2021
1Q 2021
4Q 2020
3Q 2020
21.7x
17.7x
9.3x
0x
5x
10x
15x
20x
25x
30x
35x
40x
45x
2Q 2022
1Q 2022
4Q 2021
3Q 2021
2Q 2021
1Q 2021
4Q 2020
3Q 2020
Median Revenue multiples from each MCM group. Data source: Bloomberg
Revenue Multiples
9.08x
4.73x
3.70x
0x
2x
4x
6x
8x
10x
12x
14x
16x
2Q 2022
1Q 2022
4Q 2021
3Q 2021
2Q 2021
1Q 2021
4Q 2020
3Q 2020
© 2022 Mercer Capital // www.mercercapital.com 5
Mercer Capital’s Value Focus: Medtech  Device Industry Third Quarter 2022
4.85x
3.65x
3.98x
4.48x 4.33x 4.09x
4.43x 4.64x
4.23x
4.21x
0.00x
1.00x
2.00x
3.00x
4.00x
5.00x
6.00x
7.00x
8.00x
9.00x
4Q15 1Q16 2Q16 3Q16 4Q16 1Q17 2Q17 3Q17
75% Quartile Median 25% Quartile
Biotechnology  Life Sciences
EV / Trailing LTM EBITDA
Healthcare Technology
EV / Trailing LTM EBITDA
Medical Devices
EV / Trailing LTM EBITDA
Large, Diversified
EV / Trailing LTM EBITDA
50.8x
29.6x
13.4x
0x
10x
20x
30x
40x
50x
60x
2Q 2022
1Q 2022
4Q 2021
3Q 2021
2Q 2021
1Q 2021
4Q 2020
3Q 2020
21.7x
17.7x
9.3x
0x
5x
10x
15x
20x
25x
30x
35x
40x
45x
2Q 2022
1Q 2022
4Q 2021
3Q 2021
2Q 2021
1Q 2021
4Q 2020
3Q 2020
14.9x
13.7x
10.4x
0x
5x
10x
15x
20x
25x
2Q 2022
1Q 2022
4Q 2021
3Q 2021
2Q 2021
1Q 2021
4Q 2020
3Q 2020
Median EBITDA multiples from each MCM group. Data source: Bloomberg
EBITDA Multiples
27.6x
17.9x
13.8x
0x
5x
10x
15x
20x
25x
30x
35x
40x
45x
50x
2Q 2022
1Q 2022
4Q 2021
3Q 2021
2Q 2021
1Q 2021
4Q 2020
3Q 2020
© 2022 Mercer Capital // www.mercercapital.com 6
Mercer Capital’s Value Focus: Medtech  Device Industry Third Quarter 2022
Median measures for each group. | Data Source: Bloomberg
TTM Gross Margin TTM Operating Margin TTM RD / Revenue TTM EBITDA Margin
Sector 2Q 2022 1Q 2022 2Q 2022 1Q 2022 2Q 2022 1Q 2022 2Q 2022 1Q 2022
Biotechnology  Life Sciences 67.6% 68.8% 21.7% 20.6% 19.9% 18.2% 24.2% 26.9%
Medical Devices 64.4% 65.6% 20.2% 17.9% 7.1% 6.9% 30.0% 32.6%
Healthcare Technology 59.4% 59.7% 4.7% 5.5% 13.2% 13.2% 18.2% 17.7%
Large, Diversified 58.0% 57.0% 22.5% 22.3% 8.4% 8.3% 33.6% 33.6%
Overall Median 62.3% 63.4% 20.7% 19.1% 7.8% 7.7% 29.0% 28.8%
Revenue Growth L-T FWD Op. Earn.
Growth
Debt / EV Debt / EBITDA
Sector Q / Q Y / Y 2Q 2022 1Q 2022 2Q 2022 1Q 2022 2Q 2022 1Q 2022
Biotechnology  Life Sciences 1.0% 10.3% 12.5% 9.4% 7.3% 7.7% 1.5 1.5
Medical Devices 1.1% 10.8% 9.8% 11.0% 11.2% 7.2% 1.4 1.1
Healthcare Technology 4.5% 22.6% 9.4% 11.2% 11.9% 10.1% 1.0 0.3
Large, Diversified 0.7% 7.2% 6.4% 5.8% 19.2% 13.5% 2.3 2.3
Overall Median 1.2% 11.0% 8.8% 9.8% 11.2% 10.0% 1.6 1.5
Select
Operating
Metrics
© 2022 Mercer Capital // www.mercercapital.com 7
Mercer Capital’s Value Focus: Medtech  Device Industry Third Quarter 2022
Price ∆ Stock Price EV TTM Rev
TTM
EBITDA FWD EBITDA EV / Rev.
EV /
EBITDA
EV /
FWD EBITDA
2Q 2022 1Q 2022 2Q 2021 Qtrly Annual 2Q 2022 2Q 2022 2Q 2022 FY 2023 FY 2024 2Q 2022 2Q 2022 2023 2024
Biotechnology  Life Sciences
Biogen Inc BIIB $204 $211 $346 -3.2% -41.1% $31,263 $10,634 $5,060 $3,519 $3,354 2.94x 6.2x 8.9x 9.3x
Bio-Rad Laboratories Inc BIO 495 563 644 -12.1% -23.2% 14,135 2,871 692 691 751 4.92 20.4 20.5 18.8
BioMarin Pharmaceutical Inc BMRN 83 77 83 7.5% -0.7% 15,350 1,912 61 262 783 8.03 250.7 58.6 19.6
Sartorius Stedim Biotech DIM 314 413 471 -24.0% -33.4% 29,500 3,670 634 1,248 1,394 8.04 46.5 23.6 21.2
Eurofins Scientific SE ERF 78 98 112 -21.0% -30.6% 18,424 7,729 1,869 1,605 1,592 2.38 9.9 11.5 11.6
Gilead Sciences Inc GILD 61 58 65 5.3% -6.1% 95,848 27,515 12,620 12,815 12,559 3.48 7.6 7.5 7.6
Illumina Inc ILMN 184 349 473 -47.2% -61.0% 30,208 4,691 (1,077) 784 1,008 6.44 nm 38.5 30.0
Incyte Corp INCY 76 79 84 -4.3% -9.7% 14,168 3,320 801 807 1,180 4.27 17.7 17.6 12.0
IQVIA Holdings Inc IQV 217 231 242 -6.2% -10.5% 52,024 14,136 2,929 3,344 3,673 3.68 17.8 15.6 14.2
Lonza Group AG LONN 534 725 705 -26.4% -24.3% 39,713 6,275 (508) 1,936 2,231 6.33 nm 20.5 17.8
Mettler-Toledo International Inc MTD 1,149 1,373 1,385 -16.3% -17.1% 27,673 3,865 1,172 1,220 1,288 7.16 23.6 22.7 21.5
Regeneron Pharmaceuticals Inc REGN 591 698 559 -15.4% 5.8% 53,447 14,227 7,500 5,735 6,273 3.76 7.1 9.3 8.5
Vertex Pharmaceuticals Inc VRTX 282 261 202 8.0% 39.8% 63,740 8,350 4,400 4,907 5,455 7.63 14.5 13.0 11.7
Waters Corp WAT 331 310 346 6.6% -4.2% 21,132 2,901 1,005 1,022 1,076 7.29 21.0 20.7 19.6
Group Median -9.1% -13.8% 5.63x 17.7x 19.0x 16.0x
($Millions, except per share figures)
Data Source: Bloomberg
Public Medical Device Companies
© 2022 Mercer Capital // www.mercercapital.com 8
Mercer Capital’s Value Focus: Medtech  Device Industry Third Quarter 2022
Public Medical Device Companies (continued)
Price ∆ Stock Price EV TTM Rev
TTM
EBITDA FWD EBITDA EV / Rev.
EV /
EBITDA
EV /
FWD EBITDA
2Q 2022 1Q 2022 2Q 2021 Quarterly Annual 2Q 2022 2Q 2022 2Q 2022 FY 2023 FY 2024 2Q 2022 2Q 2022 2023 2024
Medical Devices
Terumo Corp TRUMF $30 $31 $40 -1.6% -25.1% $23,220 $6,281 $1,679 $201,453 $225,029 3.70x 13.8x 0.1x 0.1x
Sysmex Corp SSMXY 60 73 118 -18.0% -49.0% 12,079 3,180 839 107,645 116,847 3.80 14.4 0.1 0.1
Olympus Corp OCPNY 20 19 20 4.4% 1.7% 26,858 7,696 1,924 391,101 297,597 3.49 14.0 0.1 0.1
ABIOMED Inc ABMD 248 331 312 -25.3% -20.7% 10,422 974 325 295 360 10.70 32.1 35.3 28.9
Align Technology Inc ALGN 237 436 611 -45.7% -61.3% 17,620 3,990 985 1,044 1,171 4.42 17.9 16.9 15.0
Baxter International Inc BAX 64 77 79 -16.8% -19.0% 47,503 14,193 3,382 3,526 3,725 3.35 14.0 13.5 12.8
Boston Scientific Corp BSX 37 44 43 -15.9% -12.8% 62,345 12,329 3,435 3,666 4,027 5.06 18.2 17.0 15.5
Coloplast A/S COLOB 114 152 161 -24.9% -29.2% 27,222 3,216 1,155 7,695 8,758 8.46 23.6 3.5 3.1
Edwards Lifesciences Corp EW 95 118 104 -19.2% -8.2% 58,104 5,355 1,783 1,975 2,106 10.85 32.6 29.4 27.6
Hologic Inc HOLX 69 77 67 -9.8% 3.9% 18,092 5,392 2,548 2,044 1,260 3.36 7.1 8.9 14.4
IDEXX Laboratories Inc IDXX 351 547 632 -35.9% -44.5% 30,550 3,309 994 1,019 1,196 9.23 30.7 30.0 25.5
Intuitive Surgical Inc ISRG 201 302 307 -33.5% -34.5% 67,242 5,964 2,072 2,415 2,789 11.28 32.5 27.8 24.1
ResMed Inc RMD 209 242 244 -13.4% -14.4% 31,277 3,444 1,132 1,333 1,503 9.08 27.6 23.5 20.8
Smith  Nephew PLC SN/ 14 16 21 -12.8% -33.7% 14,343 5,213 1,160 1,303 1,379 2.75 12.4 11.0 10.4
Stryker Corp SYK 199 266 257 -25.3% -22.6% 87,984 17,629 4,840 4,982 5,439 4.99 18.2 17.7 16.2
Teleflex Inc TFX 246 354 400 -30.6% -38.6% 13,283 2,808 1,027 832 892 4.73 12.9 16.0 14.9
Zimmer Biomet Holdings Inc ZBH 105 128 155 -17.7% -32.1% 27,658 7,407 2,497 2,386 2,469 3.73 11.1 11.6 11.2
Group Median -18.0% -25.1% 4.73x 17.9x 16.0x 14.9x
($Millions, except per share figures)
Data Source: Bloomberg
© 2022 Mercer Capital // www.mercercapital.com 9
Mercer Capital’s Value Focus: Medtech  Device Industry Third Quarter 2022
Price ∆ Stock Price EV TTM Rev
TTM
EBITDA FWD EBITDA EV / Rev.
EV /
EBITDA
EV /
FWD EBITDA
2Q 2022 1Q 2022 2Q 2021 Quarterly Annual 2Q 2022 2Q 2022 2Q 2022 FY 2023 FY 2024 2Q 2022 2Q 2022 2023 2024
Healthcare Technology
M3 Inc MTHRY $29 $37 $73 -21.8% -60.5% $18,477 $1,785 $665 $84,942 $97,707 10.35x 27.8x 0.2x 0.2x
Change Healthcare Inc CHNG 23 22 23 5.8% 0.1% 12,213 3,335 969 1,072 1,164 3.66 12.6 11.4 10.5
Craneware PLC CRW 22 22 29 2.1% -23.3% 873 118 30 55 60 7.42 29.6 15.8 14.5
Doximity Inc DOCS 35 52 58 -33.2% -40.2% 5,990 277 52 182 227 21.59 114.9 32.9 26.4
Evolent Health Inc EVH 31 32 21 -4.9% 45.4% 2,923 1,088 66 102 147 2.69 44.0 28.5 19.8
HealthStream Inc HSTM 22 20 28 9.0% -22.3% 649 259 46 52 57 2.50 14.2 12.4 11.3
Allscripts Healthcare Solutions
Inc
MDRX 15 23 19 -34.1% -19.9% 1,363 1,055 219 169 192 1.29 6.2 8.1 7.1
NextGen Healthcare Inc NXGN 17 21 17 -16.6% 5.1% 1,138 581 100 110 120 1.96 11.4 10.3 9.5
Omnicell Inc OMCL 114 129 151 -12.2% -24.9% 5,413 1,258 176 247 301 4.30 30.8 21.9 18.0
Teladoc Health Inc TDOC 33 72 166 -54.0% -80.0% 6,084 2,234 4 233 295 2.72 1435.5 26.1 20.6
Tabula Rasa HealthCare Inc TRHC 3 6 50 -55.4% -94.9% 435 312 (10) 9 19 1.39 nm 49.5 23.4
Veeva Systems Inc VEEV 198 212 311 -6.8% -36.3% 28,451 1,663 494 844 983 17.10 57.6 33.7 28.9
Group Median -14.4% -24.1% 3.19x 29.6x 18.9x 16.3x
($Millions, except per share figures)
Data Source: Bloomberg
Public Medical Device Companies (continued)
© 2022 Mercer Capital // www.mercercapital.com 10
Mercer Capital’s Value Focus: Medtech  Device Industry Third Quarter 2022
Price ∆ Stock Price EV TTM Rev
TTM
EBITDA FWD EBITDA EV / Rev.
EV /
EBITDA
EV /
FWD EBITDA
2Q 2022 1Q 2022 2Q 2021 Quarterly Annual 2Q 2022 2Q 2022 2Q 2022 FY 2023 FY 2024 2Q 2022 2Q 2022 2023 2024
Large, Diversified
Agilent Technologies Inc A $119 $132 $147 -10.1% -19.2% $37,147 $6,527 $1,889 $1,947 $2,089 5.69x 19.7x 19.1x 17.8x
AbbVie Inc ABBV 152 159 107 -4.7% 41.8% 331,257 57,349 31,990 32,704 28,400 5.78 10.4 10.1 11.7
Abbott Laboratories ABT 108 117 114 -7.8% -4.8% 196,784 45,548 13,861 12,096 11,221 4.32 14.2 16.3 17.5
Amgen Inc AMGN 241 238 234 1.4% 3.1% 158,483 26,384 15,562 14,931 15,085 6.01 10.2 10.6 10.5
Becton Dickinson and Co BDX 246 258 233 -4.6% 5.4% 85,548 19,748 6,626 4,792 5,300 4.33 12.9 17.9 16.1
Danaher Corp DHR 254 293 267 -13.5% -5.2% 200,366 30,816 10,795 10,584 10,914 6.50 18.6 18.9 18.4
Johnson  Johnson JNJ 176 175 160 0.8% 10.5% 463,656 95,588 33,127 33,842 36,247 4.85 14.0 13.7 12.8
Medtronic PLC MDT 89 109 120 -18.5% -25.9% 133,447 31,797 9,718 9,746 10,225 4.20 13.7 13.7 13.1
Koninklijke Philips NV PHIA 22 30 48 -27.3% -54.9% 26,138 19,411 2,939 2,518 3,016 1.35 8.9 10.4 8.7
PerkinElmer Inc PKI 142 174 154 -18.4% -7.7% 22,241 5,020 1,740 1,413 1,143 4.43 12.8 15.7 19.5
Roche Holding AG ROG 334 397 367 -15.9% -8.9% 290,032 69,083 27,883 25,653 25,864 4.20 10.4 11.3 11.2
Siemens Healthineers AG SHL 51 62 61 -18.4% -15.9% 73,209 24,033 4,919 4,451 4,591 3.05 14.9 16.4 15.9
Thermo Fisher Scientific Inc TMO 543 590 503 -8.0% 7.9% 240,936 42,820 12,902 11,904 12,421 5.63 18.7 20.2 19.4
Group Median -10.1% -5.2% 4.43x 13.7x 15.7x 15.9x
($Millions, except per share figures)
Data Source: Bloomberg
Public Medical Device Companies (continued)
© 2022 Mercer Capital // www.mercercapital.com 11
Mercer Capital’s Value Focus: Medtech  Device Industry Third Quarter 2022
Announced Transactions During 2Q 2022
Implied EV
Acquirer Target
Announce
Date
Transaction
Value
Implied
EV Revenue EBIT EBITDA Target Sector
Pfizer Inc. Biohaven Pharmaceutical Holding
Company Ltd.
5/10/22 $12,184 $11,891 16.12x nm nm Biotechnology
Bristol-Myers Squibb Company Turning Point Therapeutics, Inc. 6/3/22 3,976 3,058 505.14 nm nm Biotechnology
GSK plc Affinivax, Inc. 5/31/22 3,300 3,300 nm nm nm Biotechnology
GlaxoSmithKline plc (nka:GSK plc) Sierra Oncology, Inc. 4/13/22 1,931 1,657 nm nm nm Biotechnology
Optum Health Solutions (UK) Limited EMIS Group plc 4/8/22 1,632 1,549 7.07 32.6 27.8 Health Care Technology
Becton, Dickinson and Company Parata Systems, LLC 6/6/22 1,525 1,525 6.93 nm nm Life Sciences Tools and Services
ArchiMed SAS; Med Platform II Natus Medical Incorporated 4/18/22 1,207 1,122 2.35 36.3 17.0 Health Care Equipment
ResMed Germany Inc. MediFox GmbH 6/14/22 990 990 nm nm nm Health Care Technology
Gurnet Point Capital Limited; Patient Square Capital, LP Radius Health, Inc. 6/23/22 893 821 3.79 nm nm Biotechnology
EQT Partners AB; EQT IX SPT Labtech Ltd 6/22/22 800 800 nm nm nm Life Sciences Tools and Services
Ipsen Biopharmaceuticals, Inc. Epizyme, Inc. 6/27/22 707 507 13.18 nm nm Biotechnology
Wallaby Medical, LLC. phenox GmbH 4/21/22 543 543 nm nm nm Health Care Equipment
Pfizer Inc. ReViral Ltd 4/7/22 525 525 nm nm nm Biotechnology
Regeneron Pharmaceuticals, Inc. Checkmate Pharmaceuticals, Inc. 4/19/22 275 215 nm nm nm Biotechnology
CONMED Corporation In2Bones Global, Inc. 5/4/22 255 255 6.93 nm nm Health Care Equipment
Galapagos NV CellPoint B.V. 6/21/22 237 237 nm nm nm Biotechnology
ICF Incorporated, L.L.C. SemanticBits, LLC 6/8/22 220 220 nm nm nm Health Care Technology
invoX Pharma Limited F-star Therapeutics, Inc. 6/23/22 181 112 5.40 nm nm Biotechnology
Transaction values over $100 million; Presented in $millions
Data Source: Capital IQ
Mergers  Acquisitions
Mergers  Acquisitions
© 2022 Mercer Capital // www.mercercapital.com 12
Mercer Capital’s Value Focus: Medtech  Device Industry Third Quarter 2022
Announced Transactions During 2Q 2022
Implied EV
Acquirer Target
Announce
Date
Transaction
Value
Implied
EV Revenue EBIT EBITDA Target Sector
Kennedy Lewis Investment Management LLC; Kennedy
Lewis Capital Partners Master Fund II LP; Kennedy
Lewis Capital Partners Master Fund III LP
Rapid Micro Biosystems, Inc. 6/30/22 170 33 1.48 nm nm Life Sciences Tools and Services
Castle Biosciences, Inc. AltheaDx, Inc. 4/4/22 143 143 142.62 nm nm Life Sciences Tools and Services
Integer Holdings Corporation Connemara Biomedical Holdings
Teoranta
4/7/22 142 142 8.34 nm nm Biotechnology
Advanced Instruments, LLC Artel, Inc. 4/26/22 140 140 7.00 nm 28.0 Life Sciences Tools and Services
Straumann Holding AG Sunshine Smile GmbH 5/20/22 138 138 nm nm nm Health Care Supplies
Cochlear Limited Oticon Medical A/S 4/27/22 120 120 1.64 nm nm Health Care Equipment
LivaNova PLC ALung Technologies, Inc. 5/4/22 110 110 nm nm nm Health Care Equipment
Transaction values over $100 million; Presented in $millions
Data Source: Capital IQ
Mergers  Acquisitions (cont.)
$143 $190 $136 $181 $254 $113 $52
226
206
220
261
360
189
108
2017 2018 2019 2020 2021 YTD 2021 YTD 2022
Transaction Volume ($Billions) Deal Count
Medtech  Device MA
© 2022 Mercer Capital // www.mercercapital.com 13
Mercer Capital’s Value Focus: Medtech  Device Industry Third Quarter 2022
Completed Initial Public Offerings During 2Q 2022
Issuer Ticker IPO Date IPO Price
Gross
Proceeds
($mil)
6/30/22
Stock
Price
Return
Since
IPO
6/30/22
Market
Cap Industry
Heart Test Laboratories, Inc. NasdaqCM:HSCS 6/15/22 $4.25 $6.4 $1.87 -55.9% $15.2 Health Care Equipment
Psych Capital Plc OFEX:PSY 6/9/22 0.06 1.0 0.07 6.7% 19.4 Health Care Technology
Sensidose AB NGM:SENSI 5/9/22 1.06 2.4 0.34 -67.8% 4.1 Health Care Equipment
PepGen Inc. NasdaqGS:PEPG 5/5/22 12.00 108.0 9.93 -17.3% 234.7 Biotechnology
Bausch + Lomb Corporation NYSE:BLCO 5/5/22 18.00 630.0 15.24 -15.3% 5,334.0 Health Care Supplies
HilleVax, Inc. NasdaqGS:HLVX 4/28/22 17.00 200.0 10.93 -35.7% 339.9 Biotechnology
Tenon Medical, Inc. NasdaqCM:TNON 4/26/22 5.00 16.0 2.26 -54.8% 25.4 Health Care Equipment
Promimic AB (publ) OM:PRO 4/25/22 1.65 1.7 1.17 -28.8% 20.4 Life Sciences Tools and
Services
Aclarion, Inc. NasdaqCM:ACON 4/21/22 4.35 9.4 0.91 -79.0% 7.1 Health Care Technology
Sharps Technology, Inc. NasdaqCM:STSS 4/13/22 4.25 15.9 0.96 -77.4% 8.8 Health Care Supplies
Tendo AB NGM:TENDO 4/6/22 1.43 2.0 0.38 -73.7% 2.4 Health Care Equipment
S.M.A.I.O S.A. ENXTPA:ALSMA 4/1/22 6.11 11.3 4.60 -24.8% 24.0 Health Care Equipment
Data Source: Capital IQ
Initial Public Offerings
© 2022 Mercer Capital // www.mercercapital.com 14
Mercer Capital’s Value Focus: Medtech  Device Industry Third Quarter 2022
Initial Public
Offerings
(continued)
Medtech  Device IPOs
$3.9 $10.6 $12.7 $20.4 $24.2 $14.1
$1.4
77 75
74
113
177
89
24
2017 2018 2019 2020 2021 YTD 2021 YTD 2022
Amount Raised ($Billions) Number of IPOs
Source: Capital IQ; Mercer Capital Analysis
Mercer Capital
www.mercercapital.com

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Mercer Capital's Value Focus:Medtech and Device| Q3 2022

  • 1. VALUE FOCUS Medtech & Device Industry Third Quarter 2022 The update includes a review of market performance, valuation multiple trends, operating metrics, and other market data. This issue also includes a review of M&A and IPO activity during the second quarter of 2022. Mercer Capital has broad experience in providing valuation services to medtech and device start-ups, larger public and private companies, and private equity and venture capital funds involved in the sector. Please contact us to discuss how we may be of help. BUSINESS VALUATION & FINANCIAL ADVISORY SERVICES
  • 2. Copyright © 2022 Mercer Capital Management, Inc. All rights reserved. It is illegal under Federal law to reproduce this publication or any portion of its contents without the publisher’s permission. Media quotations with source attribution are encouraged. Reporters requesting additional information or editorial comment should contact Barbara Walters Price at 901.685.2120. Mercer Capital’s Industry Focus is published quarterly and does not constitute legal or financial consulting advice. It is offered as an informa- tion service to our clients and friends. Those interested in specific guidance for legal or accounting matters should seek competent professional advice. Inquiries to discuss specific valuation matters are welcomed. To add your name to our mailing list to receive this complimentary publication, visit our web site at www.mercercapital.com. Contact Us BUSINESS VALUATION & FINANCIAL ADVISORY SERVICES Medtech & Device Industry Services Mercer Capital provides valuation services to start ups, larger public and private companies, and private equity and venture capital funds. Contact a Mercer Capital professional to discuss your needs in confidence. Sujan Rajbhandary, CFA 901.322.9749 sujanr@mercercapital.com Travis W. Harms, CFA, CPA/ABV 901.322.9760 harmst@mercercapital.com J. David Smith, ASA, CFA 713.239.1005 smithd@mercercapital.com Daniel P. McLeod, CFA 901.322.9716 mcleodd@mercercapital.com J. Davis Rolfe, Jr., CPA 901.322.9712 rolfed@mercercapital.com Follow Mercer Capital Mercer Capital @MercerCapital In This Issue Mercer Capital’s expertise in the medtech and device industry spans the following segments: • Biotechnology and life sciences • Medical devices • Healthcare technology • Large, diversified Our services include: • Purchase price allocations • Impairment testing • Portfolio valuation for LP reporting • Transaction and valuation advisory • Equity compensation valuation for tax compliance Learn More about Mercer Capital & our Medtech & Device Services at www.mercercapital.com Stock Market Performance 1 Revenue Multiples 4 EBITDA Multiples 5 Select Operating Metrics 6 Public Medical Device Companies 7 Mergers Acquisitions 11 Initial Public Offerings 13
  • 3. © 2022 Mercer Capital // www.mercercapital.com 1 Mercer Capital’s Value Focus: Medtech Device Industry Third Quarter 2022 The SP 500 declined 16.4% during the second quarter of 2022 as the market downturn that began earlier in the year gathered pace. As the Fed maintained an aggressive stance to counter inflation by raising interest rates and signaling further increases, broader market moves reflected the increase in cost of capital. The medtech and device industry did not remain unscathed by the general trend. Compared to the prior quarter, estimates of forward earnings and cash flows changed only modestly but implied valuation multiples compressed meaningfully. Perhaps, (downward) revision of earnings estimates is a lagging feature that will manifest more noticeably later in the year if worries about the decelerating economy persist. Amid the stock market turmoil, quarterly and year-to-date MA and IPO deal activity also slowed down compared to the same periods in the prior year. While three of four sub-sectors tracked by Mercer Capital outperformed the broader index in terms of stock price performance, the medical devices group was a notable laggard. The group of large, diversified companies was the only sub-sector that outperformed SP 500 during the first two quarters of 2022 and the year ended 2022. • A market-capitalization weighted index of companies included in our biotechnology and life sciences sub-sector decreased 14.8% over the quarter ended June 2022. The top performer of the group was Vertex Pharmaceuticals, which posted an 8.0% return. VRTX discovers, develops, and commercializes pharmaceutical products for the treatment of cystic fibrosis, cancer, inflammatory bowel, autoimmune disease, and neurological disorders. • The medical device sub-sector index declined 28.0% in 2Q22. The group’s best performer was Olympus which returned 4.4%. Olympus manufactures optoelectronic products including cameras, video sets, endoscopes for medicine and industrial use, microscopes, analytical equipment, office communication systems, and laser optical scanners. Stock Market Performance
  • 4. © 2022 Mercer Capital // www.mercercapital.com 2 Mercer Capital’s Value Focus: Medtech Device Industry Third Quarter 2022 • The healthcare technology sub-sector decreased 11.2% over the period. HealthStream, rising 9.0%, outperformed all other constituents of the group. HSTM offers web-based solution to the continuing education and training needs of the healthcare community including workforce development, training and learning management, credentialing, privileging, provider enrollment, performance assessment, and managing simulation-based education programs. • The group of large, diversified companies decreased 8.1% over the quarter. The top performer within the group was Amgen which increased 1.4% during the period. AMGN is an independent biotechnology company that discovers, develops, manufactures, and markets medicines for grievous illnesses while focusing on human therapeutics and concentrating on innovating novel medicines based on cellular and molecular biology. 2Q 2022 Stock Price Performance -14.8% -28.0% -11.2% -8.1% -16.4% -35% -30% -25% -20% -15% -10% -5% 0% 5% 10% Mar 22 Apr 22 May 22 Jun 22 Biotechnology Life Sciences Medical Devices Healthcare Technology Large, Diversified SP 500 Stock Market Performance (cont.) Individual sub-sector performance represented by market capitalization weighted indices for each group. Data Source: Bloomberg LP; Mercer Capital Analysis
  • 5. © 2022 Mercer Capital // www.mercercapital.com 3 Mercer Capital’s Value Focus: Medtech Device Industry Third Quarter 2022 Individual sub-sector performance represented by market capitalization weighted indices for each group. Source: Bloomberg LP; Mercer Capital Analysis Stock Market Performance (cont.) LTM Stock Price Performance -14.2% -32.2% -40.6% 2.9% -11.9% -60% -50% -40% -30% -20% -10% 0% 10% 20% 30% Jun 21 Jul 21 Aug 21 Sep 21 Oct 21 Nov 21 Dec 21 Jan 22 Feb 22 Mar 22 Apr 22 May 22 Jun 22 Biotechnology Life Sciences Medical Devices Healthcare Technology Large, Diversified SP 500 YTD Stock Price Performance -22.3% -36.9% -27.2% -10.9% -20.6% -45% -40% -35% -30% -25% -20% -15% -10% -5% 0% 5% Dec 21 Jan 22 Feb 22 Mar 22 Apr 22 May 22 Jun 22 Biotechnology Life Sciences Medical Devices Healthcare Technology Large, Diversified SP 500
  • 6. © 2022 Mercer Capital // www.mercercapital.com 4 Mercer Capital’s Value Focus: Medtech Device Industry Third Quarter 2022 4.85x 3.65x 3.98x 4.48x 4.33x 4.09x 4.43x 4.64x 4.23x 4.21x 0.00x 1.00x 2.00x 3.00x 4.00x 5.00x 6.00x 7.00x 8.00x 9.00x 4Q15 1Q16 2Q16 3Q16 4Q16 1Q17 2Q17 3Q17 75% Quartile Median 25% Quartile Biotechnology Life Sciences EV / Trailing LTM Revenue Healthcare Technology EV / Trailing LTM Revenue Medical Devices EV / Trailing LTM Revenue Large, Diversified EV / Trailing LTM Revenue 8.15x 3.19x 2.37x 0x 2x 4x 6x 8x 10x 12x 14x 16x 2Q 2022 1Q 2022 4Q 2021 3Q 2021 2Q 2021 1Q 2021 4Q 2020 3Q 2020 5.69x 4.43x 4.20x 0x 1x 2x 3x 4x 5x 6x 7x 2Q 2022 1Q 2022 4Q 2021 3Q 2021 2Q 2021 1Q 2021 4Q 2020 3Q 2020 21.7x 17.7x 9.3x 0x 5x 10x 15x 20x 25x 30x 35x 40x 45x 2Q 2022 1Q 2022 4Q 2021 3Q 2021 2Q 2021 1Q 2021 4Q 2020 3Q 2020 Median Revenue multiples from each MCM group. Data source: Bloomberg Revenue Multiples 9.08x 4.73x 3.70x 0x 2x 4x 6x 8x 10x 12x 14x 16x 2Q 2022 1Q 2022 4Q 2021 3Q 2021 2Q 2021 1Q 2021 4Q 2020 3Q 2020
  • 7. © 2022 Mercer Capital // www.mercercapital.com 5 Mercer Capital’s Value Focus: Medtech Device Industry Third Quarter 2022 4.85x 3.65x 3.98x 4.48x 4.33x 4.09x 4.43x 4.64x 4.23x 4.21x 0.00x 1.00x 2.00x 3.00x 4.00x 5.00x 6.00x 7.00x 8.00x 9.00x 4Q15 1Q16 2Q16 3Q16 4Q16 1Q17 2Q17 3Q17 75% Quartile Median 25% Quartile Biotechnology Life Sciences EV / Trailing LTM EBITDA Healthcare Technology EV / Trailing LTM EBITDA Medical Devices EV / Trailing LTM EBITDA Large, Diversified EV / Trailing LTM EBITDA 50.8x 29.6x 13.4x 0x 10x 20x 30x 40x 50x 60x 2Q 2022 1Q 2022 4Q 2021 3Q 2021 2Q 2021 1Q 2021 4Q 2020 3Q 2020 21.7x 17.7x 9.3x 0x 5x 10x 15x 20x 25x 30x 35x 40x 45x 2Q 2022 1Q 2022 4Q 2021 3Q 2021 2Q 2021 1Q 2021 4Q 2020 3Q 2020 14.9x 13.7x 10.4x 0x 5x 10x 15x 20x 25x 2Q 2022 1Q 2022 4Q 2021 3Q 2021 2Q 2021 1Q 2021 4Q 2020 3Q 2020 Median EBITDA multiples from each MCM group. Data source: Bloomberg EBITDA Multiples 27.6x 17.9x 13.8x 0x 5x 10x 15x 20x 25x 30x 35x 40x 45x 50x 2Q 2022 1Q 2022 4Q 2021 3Q 2021 2Q 2021 1Q 2021 4Q 2020 3Q 2020
  • 8. © 2022 Mercer Capital // www.mercercapital.com 6 Mercer Capital’s Value Focus: Medtech Device Industry Third Quarter 2022 Median measures for each group. | Data Source: Bloomberg TTM Gross Margin TTM Operating Margin TTM RD / Revenue TTM EBITDA Margin Sector 2Q 2022 1Q 2022 2Q 2022 1Q 2022 2Q 2022 1Q 2022 2Q 2022 1Q 2022 Biotechnology Life Sciences 67.6% 68.8% 21.7% 20.6% 19.9% 18.2% 24.2% 26.9% Medical Devices 64.4% 65.6% 20.2% 17.9% 7.1% 6.9% 30.0% 32.6% Healthcare Technology 59.4% 59.7% 4.7% 5.5% 13.2% 13.2% 18.2% 17.7% Large, Diversified 58.0% 57.0% 22.5% 22.3% 8.4% 8.3% 33.6% 33.6% Overall Median 62.3% 63.4% 20.7% 19.1% 7.8% 7.7% 29.0% 28.8% Revenue Growth L-T FWD Op. Earn. Growth Debt / EV Debt / EBITDA Sector Q / Q Y / Y 2Q 2022 1Q 2022 2Q 2022 1Q 2022 2Q 2022 1Q 2022 Biotechnology Life Sciences 1.0% 10.3% 12.5% 9.4% 7.3% 7.7% 1.5 1.5 Medical Devices 1.1% 10.8% 9.8% 11.0% 11.2% 7.2% 1.4 1.1 Healthcare Technology 4.5% 22.6% 9.4% 11.2% 11.9% 10.1% 1.0 0.3 Large, Diversified 0.7% 7.2% 6.4% 5.8% 19.2% 13.5% 2.3 2.3 Overall Median 1.2% 11.0% 8.8% 9.8% 11.2% 10.0% 1.6 1.5 Select Operating Metrics
  • 9. © 2022 Mercer Capital // www.mercercapital.com 7 Mercer Capital’s Value Focus: Medtech Device Industry Third Quarter 2022 Price ∆ Stock Price EV TTM Rev TTM EBITDA FWD EBITDA EV / Rev. EV / EBITDA EV / FWD EBITDA 2Q 2022 1Q 2022 2Q 2021 Qtrly Annual 2Q 2022 2Q 2022 2Q 2022 FY 2023 FY 2024 2Q 2022 2Q 2022 2023 2024 Biotechnology Life Sciences Biogen Inc BIIB $204 $211 $346 -3.2% -41.1% $31,263 $10,634 $5,060 $3,519 $3,354 2.94x 6.2x 8.9x 9.3x Bio-Rad Laboratories Inc BIO 495 563 644 -12.1% -23.2% 14,135 2,871 692 691 751 4.92 20.4 20.5 18.8 BioMarin Pharmaceutical Inc BMRN 83 77 83 7.5% -0.7% 15,350 1,912 61 262 783 8.03 250.7 58.6 19.6 Sartorius Stedim Biotech DIM 314 413 471 -24.0% -33.4% 29,500 3,670 634 1,248 1,394 8.04 46.5 23.6 21.2 Eurofins Scientific SE ERF 78 98 112 -21.0% -30.6% 18,424 7,729 1,869 1,605 1,592 2.38 9.9 11.5 11.6 Gilead Sciences Inc GILD 61 58 65 5.3% -6.1% 95,848 27,515 12,620 12,815 12,559 3.48 7.6 7.5 7.6 Illumina Inc ILMN 184 349 473 -47.2% -61.0% 30,208 4,691 (1,077) 784 1,008 6.44 nm 38.5 30.0 Incyte Corp INCY 76 79 84 -4.3% -9.7% 14,168 3,320 801 807 1,180 4.27 17.7 17.6 12.0 IQVIA Holdings Inc IQV 217 231 242 -6.2% -10.5% 52,024 14,136 2,929 3,344 3,673 3.68 17.8 15.6 14.2 Lonza Group AG LONN 534 725 705 -26.4% -24.3% 39,713 6,275 (508) 1,936 2,231 6.33 nm 20.5 17.8 Mettler-Toledo International Inc MTD 1,149 1,373 1,385 -16.3% -17.1% 27,673 3,865 1,172 1,220 1,288 7.16 23.6 22.7 21.5 Regeneron Pharmaceuticals Inc REGN 591 698 559 -15.4% 5.8% 53,447 14,227 7,500 5,735 6,273 3.76 7.1 9.3 8.5 Vertex Pharmaceuticals Inc VRTX 282 261 202 8.0% 39.8% 63,740 8,350 4,400 4,907 5,455 7.63 14.5 13.0 11.7 Waters Corp WAT 331 310 346 6.6% -4.2% 21,132 2,901 1,005 1,022 1,076 7.29 21.0 20.7 19.6 Group Median -9.1% -13.8% 5.63x 17.7x 19.0x 16.0x ($Millions, except per share figures) Data Source: Bloomberg Public Medical Device Companies
  • 10. © 2022 Mercer Capital // www.mercercapital.com 8 Mercer Capital’s Value Focus: Medtech Device Industry Third Quarter 2022 Public Medical Device Companies (continued) Price ∆ Stock Price EV TTM Rev TTM EBITDA FWD EBITDA EV / Rev. EV / EBITDA EV / FWD EBITDA 2Q 2022 1Q 2022 2Q 2021 Quarterly Annual 2Q 2022 2Q 2022 2Q 2022 FY 2023 FY 2024 2Q 2022 2Q 2022 2023 2024 Medical Devices Terumo Corp TRUMF $30 $31 $40 -1.6% -25.1% $23,220 $6,281 $1,679 $201,453 $225,029 3.70x 13.8x 0.1x 0.1x Sysmex Corp SSMXY 60 73 118 -18.0% -49.0% 12,079 3,180 839 107,645 116,847 3.80 14.4 0.1 0.1 Olympus Corp OCPNY 20 19 20 4.4% 1.7% 26,858 7,696 1,924 391,101 297,597 3.49 14.0 0.1 0.1 ABIOMED Inc ABMD 248 331 312 -25.3% -20.7% 10,422 974 325 295 360 10.70 32.1 35.3 28.9 Align Technology Inc ALGN 237 436 611 -45.7% -61.3% 17,620 3,990 985 1,044 1,171 4.42 17.9 16.9 15.0 Baxter International Inc BAX 64 77 79 -16.8% -19.0% 47,503 14,193 3,382 3,526 3,725 3.35 14.0 13.5 12.8 Boston Scientific Corp BSX 37 44 43 -15.9% -12.8% 62,345 12,329 3,435 3,666 4,027 5.06 18.2 17.0 15.5 Coloplast A/S COLOB 114 152 161 -24.9% -29.2% 27,222 3,216 1,155 7,695 8,758 8.46 23.6 3.5 3.1 Edwards Lifesciences Corp EW 95 118 104 -19.2% -8.2% 58,104 5,355 1,783 1,975 2,106 10.85 32.6 29.4 27.6 Hologic Inc HOLX 69 77 67 -9.8% 3.9% 18,092 5,392 2,548 2,044 1,260 3.36 7.1 8.9 14.4 IDEXX Laboratories Inc IDXX 351 547 632 -35.9% -44.5% 30,550 3,309 994 1,019 1,196 9.23 30.7 30.0 25.5 Intuitive Surgical Inc ISRG 201 302 307 -33.5% -34.5% 67,242 5,964 2,072 2,415 2,789 11.28 32.5 27.8 24.1 ResMed Inc RMD 209 242 244 -13.4% -14.4% 31,277 3,444 1,132 1,333 1,503 9.08 27.6 23.5 20.8 Smith Nephew PLC SN/ 14 16 21 -12.8% -33.7% 14,343 5,213 1,160 1,303 1,379 2.75 12.4 11.0 10.4 Stryker Corp SYK 199 266 257 -25.3% -22.6% 87,984 17,629 4,840 4,982 5,439 4.99 18.2 17.7 16.2 Teleflex Inc TFX 246 354 400 -30.6% -38.6% 13,283 2,808 1,027 832 892 4.73 12.9 16.0 14.9 Zimmer Biomet Holdings Inc ZBH 105 128 155 -17.7% -32.1% 27,658 7,407 2,497 2,386 2,469 3.73 11.1 11.6 11.2 Group Median -18.0% -25.1% 4.73x 17.9x 16.0x 14.9x ($Millions, except per share figures) Data Source: Bloomberg
  • 11. © 2022 Mercer Capital // www.mercercapital.com 9 Mercer Capital’s Value Focus: Medtech Device Industry Third Quarter 2022 Price ∆ Stock Price EV TTM Rev TTM EBITDA FWD EBITDA EV / Rev. EV / EBITDA EV / FWD EBITDA 2Q 2022 1Q 2022 2Q 2021 Quarterly Annual 2Q 2022 2Q 2022 2Q 2022 FY 2023 FY 2024 2Q 2022 2Q 2022 2023 2024 Healthcare Technology M3 Inc MTHRY $29 $37 $73 -21.8% -60.5% $18,477 $1,785 $665 $84,942 $97,707 10.35x 27.8x 0.2x 0.2x Change Healthcare Inc CHNG 23 22 23 5.8% 0.1% 12,213 3,335 969 1,072 1,164 3.66 12.6 11.4 10.5 Craneware PLC CRW 22 22 29 2.1% -23.3% 873 118 30 55 60 7.42 29.6 15.8 14.5 Doximity Inc DOCS 35 52 58 -33.2% -40.2% 5,990 277 52 182 227 21.59 114.9 32.9 26.4 Evolent Health Inc EVH 31 32 21 -4.9% 45.4% 2,923 1,088 66 102 147 2.69 44.0 28.5 19.8 HealthStream Inc HSTM 22 20 28 9.0% -22.3% 649 259 46 52 57 2.50 14.2 12.4 11.3 Allscripts Healthcare Solutions Inc MDRX 15 23 19 -34.1% -19.9% 1,363 1,055 219 169 192 1.29 6.2 8.1 7.1 NextGen Healthcare Inc NXGN 17 21 17 -16.6% 5.1% 1,138 581 100 110 120 1.96 11.4 10.3 9.5 Omnicell Inc OMCL 114 129 151 -12.2% -24.9% 5,413 1,258 176 247 301 4.30 30.8 21.9 18.0 Teladoc Health Inc TDOC 33 72 166 -54.0% -80.0% 6,084 2,234 4 233 295 2.72 1435.5 26.1 20.6 Tabula Rasa HealthCare Inc TRHC 3 6 50 -55.4% -94.9% 435 312 (10) 9 19 1.39 nm 49.5 23.4 Veeva Systems Inc VEEV 198 212 311 -6.8% -36.3% 28,451 1,663 494 844 983 17.10 57.6 33.7 28.9 Group Median -14.4% -24.1% 3.19x 29.6x 18.9x 16.3x ($Millions, except per share figures) Data Source: Bloomberg Public Medical Device Companies (continued)
  • 12. © 2022 Mercer Capital // www.mercercapital.com 10 Mercer Capital’s Value Focus: Medtech Device Industry Third Quarter 2022 Price ∆ Stock Price EV TTM Rev TTM EBITDA FWD EBITDA EV / Rev. EV / EBITDA EV / FWD EBITDA 2Q 2022 1Q 2022 2Q 2021 Quarterly Annual 2Q 2022 2Q 2022 2Q 2022 FY 2023 FY 2024 2Q 2022 2Q 2022 2023 2024 Large, Diversified Agilent Technologies Inc A $119 $132 $147 -10.1% -19.2% $37,147 $6,527 $1,889 $1,947 $2,089 5.69x 19.7x 19.1x 17.8x AbbVie Inc ABBV 152 159 107 -4.7% 41.8% 331,257 57,349 31,990 32,704 28,400 5.78 10.4 10.1 11.7 Abbott Laboratories ABT 108 117 114 -7.8% -4.8% 196,784 45,548 13,861 12,096 11,221 4.32 14.2 16.3 17.5 Amgen Inc AMGN 241 238 234 1.4% 3.1% 158,483 26,384 15,562 14,931 15,085 6.01 10.2 10.6 10.5 Becton Dickinson and Co BDX 246 258 233 -4.6% 5.4% 85,548 19,748 6,626 4,792 5,300 4.33 12.9 17.9 16.1 Danaher Corp DHR 254 293 267 -13.5% -5.2% 200,366 30,816 10,795 10,584 10,914 6.50 18.6 18.9 18.4 Johnson Johnson JNJ 176 175 160 0.8% 10.5% 463,656 95,588 33,127 33,842 36,247 4.85 14.0 13.7 12.8 Medtronic PLC MDT 89 109 120 -18.5% -25.9% 133,447 31,797 9,718 9,746 10,225 4.20 13.7 13.7 13.1 Koninklijke Philips NV PHIA 22 30 48 -27.3% -54.9% 26,138 19,411 2,939 2,518 3,016 1.35 8.9 10.4 8.7 PerkinElmer Inc PKI 142 174 154 -18.4% -7.7% 22,241 5,020 1,740 1,413 1,143 4.43 12.8 15.7 19.5 Roche Holding AG ROG 334 397 367 -15.9% -8.9% 290,032 69,083 27,883 25,653 25,864 4.20 10.4 11.3 11.2 Siemens Healthineers AG SHL 51 62 61 -18.4% -15.9% 73,209 24,033 4,919 4,451 4,591 3.05 14.9 16.4 15.9 Thermo Fisher Scientific Inc TMO 543 590 503 -8.0% 7.9% 240,936 42,820 12,902 11,904 12,421 5.63 18.7 20.2 19.4 Group Median -10.1% -5.2% 4.43x 13.7x 15.7x 15.9x ($Millions, except per share figures) Data Source: Bloomberg Public Medical Device Companies (continued)
  • 13. © 2022 Mercer Capital // www.mercercapital.com 11 Mercer Capital’s Value Focus: Medtech Device Industry Third Quarter 2022 Announced Transactions During 2Q 2022 Implied EV Acquirer Target Announce Date Transaction Value Implied EV Revenue EBIT EBITDA Target Sector Pfizer Inc. Biohaven Pharmaceutical Holding Company Ltd. 5/10/22 $12,184 $11,891 16.12x nm nm Biotechnology Bristol-Myers Squibb Company Turning Point Therapeutics, Inc. 6/3/22 3,976 3,058 505.14 nm nm Biotechnology GSK plc Affinivax, Inc. 5/31/22 3,300 3,300 nm nm nm Biotechnology GlaxoSmithKline plc (nka:GSK plc) Sierra Oncology, Inc. 4/13/22 1,931 1,657 nm nm nm Biotechnology Optum Health Solutions (UK) Limited EMIS Group plc 4/8/22 1,632 1,549 7.07 32.6 27.8 Health Care Technology Becton, Dickinson and Company Parata Systems, LLC 6/6/22 1,525 1,525 6.93 nm nm Life Sciences Tools and Services ArchiMed SAS; Med Platform II Natus Medical Incorporated 4/18/22 1,207 1,122 2.35 36.3 17.0 Health Care Equipment ResMed Germany Inc. MediFox GmbH 6/14/22 990 990 nm nm nm Health Care Technology Gurnet Point Capital Limited; Patient Square Capital, LP Radius Health, Inc. 6/23/22 893 821 3.79 nm nm Biotechnology EQT Partners AB; EQT IX SPT Labtech Ltd 6/22/22 800 800 nm nm nm Life Sciences Tools and Services Ipsen Biopharmaceuticals, Inc. Epizyme, Inc. 6/27/22 707 507 13.18 nm nm Biotechnology Wallaby Medical, LLC. phenox GmbH 4/21/22 543 543 nm nm nm Health Care Equipment Pfizer Inc. ReViral Ltd 4/7/22 525 525 nm nm nm Biotechnology Regeneron Pharmaceuticals, Inc. Checkmate Pharmaceuticals, Inc. 4/19/22 275 215 nm nm nm Biotechnology CONMED Corporation In2Bones Global, Inc. 5/4/22 255 255 6.93 nm nm Health Care Equipment Galapagos NV CellPoint B.V. 6/21/22 237 237 nm nm nm Biotechnology ICF Incorporated, L.L.C. SemanticBits, LLC 6/8/22 220 220 nm nm nm Health Care Technology invoX Pharma Limited F-star Therapeutics, Inc. 6/23/22 181 112 5.40 nm nm Biotechnology Transaction values over $100 million; Presented in $millions Data Source: Capital IQ Mergers Acquisitions Mergers Acquisitions
  • 14. © 2022 Mercer Capital // www.mercercapital.com 12 Mercer Capital’s Value Focus: Medtech Device Industry Third Quarter 2022 Announced Transactions During 2Q 2022 Implied EV Acquirer Target Announce Date Transaction Value Implied EV Revenue EBIT EBITDA Target Sector Kennedy Lewis Investment Management LLC; Kennedy Lewis Capital Partners Master Fund II LP; Kennedy Lewis Capital Partners Master Fund III LP Rapid Micro Biosystems, Inc. 6/30/22 170 33 1.48 nm nm Life Sciences Tools and Services Castle Biosciences, Inc. AltheaDx, Inc. 4/4/22 143 143 142.62 nm nm Life Sciences Tools and Services Integer Holdings Corporation Connemara Biomedical Holdings Teoranta 4/7/22 142 142 8.34 nm nm Biotechnology Advanced Instruments, LLC Artel, Inc. 4/26/22 140 140 7.00 nm 28.0 Life Sciences Tools and Services Straumann Holding AG Sunshine Smile GmbH 5/20/22 138 138 nm nm nm Health Care Supplies Cochlear Limited Oticon Medical A/S 4/27/22 120 120 1.64 nm nm Health Care Equipment LivaNova PLC ALung Technologies, Inc. 5/4/22 110 110 nm nm nm Health Care Equipment Transaction values over $100 million; Presented in $millions Data Source: Capital IQ Mergers Acquisitions (cont.) $143 $190 $136 $181 $254 $113 $52 226 206 220 261 360 189 108 2017 2018 2019 2020 2021 YTD 2021 YTD 2022 Transaction Volume ($Billions) Deal Count Medtech Device MA
  • 15. © 2022 Mercer Capital // www.mercercapital.com 13 Mercer Capital’s Value Focus: Medtech Device Industry Third Quarter 2022 Completed Initial Public Offerings During 2Q 2022 Issuer Ticker IPO Date IPO Price Gross Proceeds ($mil) 6/30/22 Stock Price Return Since IPO 6/30/22 Market Cap Industry Heart Test Laboratories, Inc. NasdaqCM:HSCS 6/15/22 $4.25 $6.4 $1.87 -55.9% $15.2 Health Care Equipment Psych Capital Plc OFEX:PSY 6/9/22 0.06 1.0 0.07 6.7% 19.4 Health Care Technology Sensidose AB NGM:SENSI 5/9/22 1.06 2.4 0.34 -67.8% 4.1 Health Care Equipment PepGen Inc. NasdaqGS:PEPG 5/5/22 12.00 108.0 9.93 -17.3% 234.7 Biotechnology Bausch + Lomb Corporation NYSE:BLCO 5/5/22 18.00 630.0 15.24 -15.3% 5,334.0 Health Care Supplies HilleVax, Inc. NasdaqGS:HLVX 4/28/22 17.00 200.0 10.93 -35.7% 339.9 Biotechnology Tenon Medical, Inc. NasdaqCM:TNON 4/26/22 5.00 16.0 2.26 -54.8% 25.4 Health Care Equipment Promimic AB (publ) OM:PRO 4/25/22 1.65 1.7 1.17 -28.8% 20.4 Life Sciences Tools and Services Aclarion, Inc. NasdaqCM:ACON 4/21/22 4.35 9.4 0.91 -79.0% 7.1 Health Care Technology Sharps Technology, Inc. NasdaqCM:STSS 4/13/22 4.25 15.9 0.96 -77.4% 8.8 Health Care Supplies Tendo AB NGM:TENDO 4/6/22 1.43 2.0 0.38 -73.7% 2.4 Health Care Equipment S.M.A.I.O S.A. ENXTPA:ALSMA 4/1/22 6.11 11.3 4.60 -24.8% 24.0 Health Care Equipment Data Source: Capital IQ Initial Public Offerings
  • 16. © 2022 Mercer Capital // www.mercercapital.com 14 Mercer Capital’s Value Focus: Medtech Device Industry Third Quarter 2022 Initial Public Offerings (continued) Medtech Device IPOs $3.9 $10.6 $12.7 $20.4 $24.2 $14.1 $1.4 77 75 74 113 177 89 24 2017 2018 2019 2020 2021 YTD 2021 YTD 2022 Amount Raised ($Billions) Number of IPOs Source: Capital IQ; Mercer Capital Analysis