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Fundamental to Biomedical instrument
Basics of measuring instrumentation system
Kedir Ali
Department of Biomedical Engineering
Kombolcha Institute of Technology
Wollo University
Outlines
• Measurement
• Metrology
• Instrumentation
• Biomedical instrumentation system
• Components of Biomedical instrumentation system
• Types of medical instruments
History of measurement
• Measurement originate in 3rd & 4th millennium BC by ancient
people of Egypt, Mesopotamia, Indus Valley and Elam (Iran).
• They uses measurement for purposes of agriculture, construction
and trade.
Example: Cubit…
Cont.
• Stethoscope (1816)
• Wilhelm Conrad Rontgen X-ray
• 1965 First commercial Ultrasound
…etc..
Measurement
• A process of gathering information from a physical world and
comparing with agreed standards.
• Obtain correct value of the measured physical quantity.
• Essential for observing and testing scientific and technological
investigations.
• Measurements are carried out by using instruments.
Standards of Measurement System
• A fundamental references for which all other measuring devices
are compared
• Used for calibrations of measuring instruments (minimizing
error)
• On the basis of their function and application, standards are
classified as; international, primary, secondary and working
standards.
Cont.
1. International standards
• Defined on the basis of international agreement
• Define units precisely
• Preserved carefully under standard atmospheric condition
• Not applicable for measurement (only for comparison)
2. Primary standards
• Used for calibrating secondary standards
• Not available outside of national laboratory
• Compared with international standards after long interval
Cont.
3. Secondary standards
• Basic reference standards used in industrial measurement laboratories
• Compared with primary standards on periodic basis
4. Working standards
• Used as a reference purpose in lab and workshops
• Has an accuracy lower than the rest three
• Material used to make the standards are lower graded & relatively
cheap
Measurement Errors
The result of every measurement by any measuring instrument
contains some uncertainty – error.
Absolute Error : difference between the measured value & true
value of a quantity.
Relative Error: ratio of absolute error to the true value of the
quantity.
Classification of Errors
There are three main classes of errors, namely:
1. Gross Errors
• Occurred due to human mistake during measurement
Arise due to:
• Carelessness of the measurer
• Luck of ability to use the tool
• Inability to interpret the measured result
Cont.
2. Systematic Errors
• Occurred by any factor that systematically affect measurement.
• Caused by defective instruments, inherent limitation of measuring
device, and wrong construction of device – instrumental.
• Imperfect method of observation, wrong selection of measurement
tool, error while reading values – observational.
• Environmental interference, external conditions (temperature,
humidity, sound, …) – environmental error.
Cont.
3. Random Errors
• Errors caused by any factors that randomly affect the
measurement.
• Normal or unavoidable errors due to unknown sources.
• Cannot determine under ordinary measurement process.
How to reduce errors in measurement
• Use standard and properly validated instrument
• Pre-test the instrument
• Double check measurement & measurement tool
• Check the reliability, sensitivity of the scale
• Etc.…
Metrology
• Metrology derived from two words “metro” which means
measure, and “logos” which means study.
• A science of measurement and its application.
• Focuses on advancing measurement science to improve quality of
life.
Types of metrology
Scientific metrology
• Concerned with the establishment of new units and methods of
measurement.
• Deals with the specification of new standards, their realization,
and the conveyance of these standards to users.
Cont.
Applied or industrial metrology
• Deals with the use of measurement and its application to
industrial and manufacturing processes.
• It seeks to establish the importance of measurement in general.
• Ensures the functionality of measuring equipment, proper calibration,
and quality control.
Metrology calibration?
• An act of assessing and standardizing the accuracy and precision of
measuring equipment.
Cont.
Legal metrology
• Concerned with the regulatory requirements of measurements.
• Includes measurement methods, and units of measurement.
• The regulations aim to ensure fair trade, furthermore to protect
consumer rights, ensure public safety, protect the environment
and enable taxation.
Instrumentation
• Development and use of precise measuring equipment.
• Devices used in measurement system.
Medical Instrumentation system
• To measure or determine the presence of some physical quantity
that can assist the medical personnel to make better diagnosis
and treatment.
Components of instrumentation system
Measurand
• The physical quantity or condition that the instrumentation
system measures.
• The source for the measurand is the human body which
generates a variety of signals.
Cont.
Transducer
• A device that converts one form of energy to other.
• a piezo-electric crystal converts mechanical vibrations into
an electrical signal
• Provides a usable output in response to the measurand.
Cont.
Sensor
• Converts a physical measurand to an electrical signal.
• The sensor should be minimally invasive and interface with the
living system with minimum extraction of energy.
Cont.
Signal Conditioner
• Convert the output of the transducer into an electrical quantity
suitable for operation of the display or recording system.
• Includes amplification, filtering analog-to-digital and digital-to-
analog conversion or signal transmission circuitry.
Cont.
Display System
• Provides a visible representation of the quantity on the screen of
a cathode ray tube or in numerical form.
• Visual, audible signals from alarm
Cont.
Alarm System
• Notify when the measurand goes beyond preset limits.
Cont.
Data transmission & Storage
• Maintains the data for future reference (hard copy or memories).
General concerns in the design of instrumentation systems
Accuracy
Range
• The range of an instrument is generally considered to include all
the levels of input amplitude and frequency over which the
device is expected to operate.
• The objective should be to provide an instrument that will give a
usable reading from the smallest expected value of the variable
or parameter being measured to the largest.
Cont.
Sensitivity
• The sensitivity of an instrument determines how small a variation
of a variable or parameter can be reliably measured.
• The sensitivity directly determines the resolution of the device,
which is the minimum variation that can accurately be read.
• Too high a sensitivity often results in nonlinearities or instability.
Cont.
Linearity
• The degree to which variations in the output of an instrument follow
input variations.
• In a linear system the sensitivity would be the same for all absolute
levels of input, whether in the high, middle, or low portion of the range.
• In some instruments a certain form of nonlinearity is purposely
introduced to create a desired effect.
Cont.
Hysteresis
• A characteristic of some instruments whereby a given value of
the measured variable results in a different reading when
reached in an ascending direction from that obtained when it is
reached in a descending direction.
• Mechanical friction in a meter, for example, can cause the
movement of the indicating needle to lag behind corresponding
changes in the measured variable, thus resulting in a hysteresis
error in the reading.
Cont.
Frequency Response
• A variation in sensitivity over the frequency range of the
measurement.
• Flat response An instrument system should be able to respond rapidly
enough to reproduce all frequency components of the waveform with
equal sensitivity.
Cont.
Signal-to-Noise Ratio
• It is important that the signal-to-noise ratio be as high as
possible.
Types of instruments
Instruments can be subdivided into separate classes according to
several criteria.
• Active vs Passive Instruments
• Analog and Digital Instruments
• …
Cont.
Active instruments
• Quantity to be measured activates the magnitude of external power
input source that produces the measurement.
• Additional external energy input source is required.
• Output adjusted by adjusting the external energy.
• High resolution
Passive instruments
• The output is entirely produced by the quantity being measured.
• Additional external energy input source is not required.
Cont.
Analog instruments
• Output varies continuously as the quantity being measured changes.
• Output can have infinite number of values within instrument range
• Recordings are made with linear bumps & dips.
• Information is exact
Digital instruments
• Output varies in discrete steps
• Output can have finite number of values
• Recordings are made with zeros & ones
• Information are not exact as analog information
Medical equipment in different dept. of hospital
• Outpatient Department (OPD)
• Radiology department
• Pharmacy department
• Inpatient service
• Medical department
• Pathology department
• …
Reading assignment
1.Difference between sensors & transducer
Quiz-1
1. What is the purpose of measurement, instrumentation &
metrology ?
2. What purpose of signal conditioning ?

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1. Basics of Measuring Instrumentation System (2).pptx

  • 1. Fundamental to Biomedical instrument Basics of measuring instrumentation system Kedir Ali Department of Biomedical Engineering Kombolcha Institute of Technology Wollo University
  • 2. Outlines • Measurement • Metrology • Instrumentation • Biomedical instrumentation system • Components of Biomedical instrumentation system • Types of medical instruments
  • 3. History of measurement • Measurement originate in 3rd & 4th millennium BC by ancient people of Egypt, Mesopotamia, Indus Valley and Elam (Iran). • They uses measurement for purposes of agriculture, construction and trade. Example: Cubit…
  • 4. Cont. • Stethoscope (1816) • Wilhelm Conrad Rontgen X-ray • 1965 First commercial Ultrasound …etc..
  • 5. Measurement • A process of gathering information from a physical world and comparing with agreed standards. • Obtain correct value of the measured physical quantity. • Essential for observing and testing scientific and technological investigations. • Measurements are carried out by using instruments.
  • 6. Standards of Measurement System • A fundamental references for which all other measuring devices are compared • Used for calibrations of measuring instruments (minimizing error) • On the basis of their function and application, standards are classified as; international, primary, secondary and working standards.
  • 7. Cont. 1. International standards • Defined on the basis of international agreement • Define units precisely • Preserved carefully under standard atmospheric condition • Not applicable for measurement (only for comparison) 2. Primary standards • Used for calibrating secondary standards • Not available outside of national laboratory • Compared with international standards after long interval
  • 8. Cont. 3. Secondary standards • Basic reference standards used in industrial measurement laboratories • Compared with primary standards on periodic basis 4. Working standards • Used as a reference purpose in lab and workshops • Has an accuracy lower than the rest three • Material used to make the standards are lower graded & relatively cheap
  • 9. Measurement Errors The result of every measurement by any measuring instrument contains some uncertainty – error. Absolute Error : difference between the measured value & true value of a quantity. Relative Error: ratio of absolute error to the true value of the quantity.
  • 10. Classification of Errors There are three main classes of errors, namely: 1. Gross Errors • Occurred due to human mistake during measurement Arise due to: • Carelessness of the measurer • Luck of ability to use the tool • Inability to interpret the measured result
  • 11. Cont. 2. Systematic Errors • Occurred by any factor that systematically affect measurement. • Caused by defective instruments, inherent limitation of measuring device, and wrong construction of device – instrumental. • Imperfect method of observation, wrong selection of measurement tool, error while reading values – observational. • Environmental interference, external conditions (temperature, humidity, sound, …) – environmental error.
  • 12. Cont. 3. Random Errors • Errors caused by any factors that randomly affect the measurement. • Normal or unavoidable errors due to unknown sources. • Cannot determine under ordinary measurement process.
  • 13. How to reduce errors in measurement • Use standard and properly validated instrument • Pre-test the instrument • Double check measurement & measurement tool • Check the reliability, sensitivity of the scale • Etc.…
  • 14. Metrology • Metrology derived from two words “metro” which means measure, and “logos” which means study. • A science of measurement and its application. • Focuses on advancing measurement science to improve quality of life.
  • 15. Types of metrology Scientific metrology • Concerned with the establishment of new units and methods of measurement. • Deals with the specification of new standards, their realization, and the conveyance of these standards to users.
  • 16. Cont. Applied or industrial metrology • Deals with the use of measurement and its application to industrial and manufacturing processes. • It seeks to establish the importance of measurement in general. • Ensures the functionality of measuring equipment, proper calibration, and quality control. Metrology calibration? • An act of assessing and standardizing the accuracy and precision of measuring equipment.
  • 17. Cont. Legal metrology • Concerned with the regulatory requirements of measurements. • Includes measurement methods, and units of measurement. • The regulations aim to ensure fair trade, furthermore to protect consumer rights, ensure public safety, protect the environment and enable taxation.
  • 18. Instrumentation • Development and use of precise measuring equipment. • Devices used in measurement system.
  • 19. Medical Instrumentation system • To measure or determine the presence of some physical quantity that can assist the medical personnel to make better diagnosis and treatment.
  • 20. Components of instrumentation system Measurand • The physical quantity or condition that the instrumentation system measures. • The source for the measurand is the human body which generates a variety of signals.
  • 21. Cont. Transducer • A device that converts one form of energy to other. • a piezo-electric crystal converts mechanical vibrations into an electrical signal • Provides a usable output in response to the measurand.
  • 22. Cont. Sensor • Converts a physical measurand to an electrical signal. • The sensor should be minimally invasive and interface with the living system with minimum extraction of energy.
  • 23. Cont. Signal Conditioner • Convert the output of the transducer into an electrical quantity suitable for operation of the display or recording system. • Includes amplification, filtering analog-to-digital and digital-to- analog conversion or signal transmission circuitry.
  • 24. Cont. Display System • Provides a visible representation of the quantity on the screen of a cathode ray tube or in numerical form. • Visual, audible signals from alarm
  • 25. Cont. Alarm System • Notify when the measurand goes beyond preset limits.
  • 26. Cont. Data transmission & Storage • Maintains the data for future reference (hard copy or memories).
  • 27. General concerns in the design of instrumentation systems Accuracy Range • The range of an instrument is generally considered to include all the levels of input amplitude and frequency over which the device is expected to operate. • The objective should be to provide an instrument that will give a usable reading from the smallest expected value of the variable or parameter being measured to the largest.
  • 28. Cont. Sensitivity • The sensitivity of an instrument determines how small a variation of a variable or parameter can be reliably measured. • The sensitivity directly determines the resolution of the device, which is the minimum variation that can accurately be read. • Too high a sensitivity often results in nonlinearities or instability.
  • 29. Cont. Linearity • The degree to which variations in the output of an instrument follow input variations. • In a linear system the sensitivity would be the same for all absolute levels of input, whether in the high, middle, or low portion of the range. • In some instruments a certain form of nonlinearity is purposely introduced to create a desired effect.
  • 30. Cont. Hysteresis • A characteristic of some instruments whereby a given value of the measured variable results in a different reading when reached in an ascending direction from that obtained when it is reached in a descending direction. • Mechanical friction in a meter, for example, can cause the movement of the indicating needle to lag behind corresponding changes in the measured variable, thus resulting in a hysteresis error in the reading.
  • 31. Cont. Frequency Response • A variation in sensitivity over the frequency range of the measurement. • Flat response An instrument system should be able to respond rapidly enough to reproduce all frequency components of the waveform with equal sensitivity.
  • 32. Cont. Signal-to-Noise Ratio • It is important that the signal-to-noise ratio be as high as possible.
  • 33. Types of instruments Instruments can be subdivided into separate classes according to several criteria. • Active vs Passive Instruments • Analog and Digital Instruments • …
  • 34. Cont. Active instruments • Quantity to be measured activates the magnitude of external power input source that produces the measurement. • Additional external energy input source is required. • Output adjusted by adjusting the external energy. • High resolution Passive instruments • The output is entirely produced by the quantity being measured. • Additional external energy input source is not required.
  • 35. Cont. Analog instruments • Output varies continuously as the quantity being measured changes. • Output can have infinite number of values within instrument range • Recordings are made with linear bumps & dips. • Information is exact Digital instruments • Output varies in discrete steps • Output can have finite number of values • Recordings are made with zeros & ones • Information are not exact as analog information
  • 36. Medical equipment in different dept. of hospital • Outpatient Department (OPD) • Radiology department • Pharmacy department • Inpatient service • Medical department • Pathology department • …
  • 37. Reading assignment 1.Difference between sensors & transducer Quiz-1 1. What is the purpose of measurement, instrumentation & metrology ? 2. What purpose of signal conditioning ?