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DOES LOW TESTOSTERONE LEAD TO DEPRESSION?
1. DOES LOW TESTOSTERONE LEAD TO DEPRESSION?
LOW TESTOSTERONE LEAD TO DEPRESSION in Testosterone deficiency is a condition w hen the normal levels of testosterone
fall inside the male body to such level that it starts to affect the male reproductive systemand masculine characteristics(such
as muscle mass, bone health, hair density, sexualcharacteristics, etc). It may occur due to a disease or damage to the
hypothalamus, pituitary gland or testicles that inhibit hormone secretion and testosterone production.
Testosterone deficiency gives rise to a number of complications. One such complication is depression. According to International
Society of Men’s Health (ISMH), men w ith testosterone deficiencyare at higher risk of depression. The onset of depression
increases the cost of treatment of testosterone deficiency.
A clinical study w as conducted on 278 men over the age of 45 years for a period of four years. At the conclusion of the study, it w as
reported that the men w ho had low testosterone levels were four times as likely to be diagnosed w ith clinicaldepression as the men
w ho had normal levels of testosterone.
SYMPTOMS OF LOW TESTOSTERONE LEAD TO DEPRESSION IN TESTOSTERONE DEFICIENCY
Irritability
Anxiety
Sadness
Memory problems
Low sex drive
Trouble concentrating
Sleep problems
The symptoms of depression in testosterone deficiencyare often centered around headachesand backpain.
REASON BEHIND LOW TESTOSTERONE LEAD TO DEPRESSION IN TESTOSTERONE DEFICIENCY
A study conducted by Almeida et al. on low testosterone in men suggests another possibility that low er testosterone levels in male
body contributes greatly tow ards depression. They may actually directly affect serotonin levels in the brain.
Serotonin is another naturalhormone and one of its many roles is to help regulate the moods. Thus, disturbance in serotonin levels
causes depression in men w ith low testosterones.
3. Testosterone deficiency and depression can be managed together starting w ith change in lifestyle. The follow ing may help w ith both
low testosterone and stressmanagement:
Lose weight: Body fat makes estrogen, which can tip the ratio of estrogen to testosterone, which results in unfavorably low er
amounts of testosterone.
Depression also tends to cause men to exercise less and eat fattening foods more, w hich further contributesto low ertestosterone.
When body w eight is managed, the process reversesand testosterone levels tend to go back up.
4. Get enough sleep: Men under stress tend to be deficient in sleep and lack of sleep can lead to low testosterone & depression too.
During stress, body releases a hormone called as cortisol, which actively interferes with and inhibits testosterone function in the
body. Low testosterone furtherworsensthe condition of stress and the cycle continues.
Thus, taking enough sleep can help to cope with stress and can indirectly manage the levels of testosterone in the body. Sleeping
better can help to fight against stress.
Change in diet:To help boost testosterone levels naturally, high-protein and low -fat diet is recommended by physicians.
Also limit certain foods such as those, which are high in refined sugars, salt and saturated and trans fats that can elevate
triglycerides, cholesteroland fatty acids.
Exercise: Exercise in almost any form can act as a stress reliever.Regularexercise releases endorphin neurotransmitter, which
can reduce stress and help in management of stress-induced testosterone deficiency.
Regular exercise can increase self-confidence and can help in mind relaxation. It can also low er the symptoms associated w ith mild
depression and anxiety.
5. Herbs & plants: Natural anti-anxiety herbs help to release stress from body. Some of those herbs include ashwagandha,
chamomile, lavender, kava, etc. If testosterone levels in the body are boosted by herbal supplements then, stress generated
from testosterone deficiency can be managed.
ROLE OF CHEMFORCE IN MANAGEMENT OF STRESS AND TESTOSTERONE
According to the clinical study conducted by Sw aroop A et al., fenugreek seed extract(Furosap®
), the major ingredientin
CHEMFORCE is effective in the management of testosterones levelin the body.
Their clinical study proved that Furosap®
effectively increased testosteronelevels, spermprofile, mental alertness, mood and libido
in male volunteers.
Their study on 50 male volunteers showed that free testosterone levels were improved up to 46% in 90% of the study population.
6. Majority of the subjects enrolled in the study demonstrated improvements in mental alertness and mood. Libido w as significantly
improved w hich helped in the management of stress in the volunteers.
Their study proved that this herbalsupplement w as completely safe in the enrolled male volunteers as their safety parameters were
w ithin the normal range after the completion of the clinical study.
Mechanismof action:Furosap®
is know n to act due to the presence of its active constituent know n as protodioscin.
Protodioscinis a steroid saponin, w hich has been found to promote healthy testosterone levels through its effectson testosterone-
dihydrotestosterone conversion. It appears to promote healthy production of luteinizing hormone (LH). It delivers its hormonal effects
in a balanced (not over-active) fashion.
Protodioscin also promotes healthy red blood cell production, w hich ultimately supports healthy oxygen delivery throughout the
body. This combination of hormonal and circulatory effects resultsin both healthy sexualfunction and optimal athletic endurance.
Managementof testosterone levels in the body ultimately helps to manage depression.
REFERENCES
http://www.healthcommunities.com/testosterone-deficiency/overview-of-testosterone-deficiency.shtml
http://www.ismh.org/en/sys/wp-content/uploads/2012/04/2_MERYN-epidemiology-SR-formatted-and-second-checked1.pdf
http://www.healthline.com/health/low-testosterone/depression#Overview1
https://www.lucidatreatment.com/blog/mental-health/low -testosterone-depression-link/
http://jamanetw ork.com/journals/jamapsychiatry/fullarticle/482640
http://www.everydayhealth.com/hs/low-testosterone-guide/managing-stress/
https://www.anabolicmen.com/depression-testosterone/
http://grow youthful.com/remedy/testosterone.php
http://www.mayoclinic.org/healthy-lifestyle/stress-management/in-depth/exercise-and-stress/art-20044469
http://www.fasebj.org/content/30/1_Supplement/1156.7