a wide range of signs and symptoms can occur when a persons overdoses and everyone responds differently. symptoms can be often be divided into differing toxidromes. this can help one determine what class of drug or toxin is causing the difficulties.

1. SEMINAR
PRESENTED BY
LAKSHMI MANOJ

2. SIGNS AND SYMPTOMS OF
OVERDOSAGE
A wide range of signs and symptoms can occur
when a person overdoses and everyone responds
differently.
Signs and symptoms depend on a variety of factors
including:
• which substance they took
• how much they took
• how they took
• their state of health
• age , etc.

3. • The symptoms can
often be divided into
differing toxidromes.
• This can help one
determine what class
of drug or toxin is
causing the difficulties.

4. Symptoms of opioid overdose

5. Drugs or toxins frequently involved in
overdose and death
Acute alcohol
intoxication
• Ethyl alcohol
• Methanol poisoning
• Ethylene glycol
poisoning
Sedative hypnotics
• Barbiturate overdose
• Benzodiazepine
overdose

6. Diagnosis
• Determination of substance by asking the patient
• Patient’s history from friends and relatives
• Examination for toxindromes
• Drug testing
• Laboratory test such as glucose,urea,paracetamol levels and
salicylate levels

7. Antidotes
 Naloxone is the antidote
for opiates such as
heroin or morphine
 Flumazenil is the
antidote for
benzodiazepine
 Activated charcoal is
frequently
recommended if
available within one
hour of ingestion