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Imhof eshre press briefing stockholm july 4, 2011
1. Fertility Europe
United in Europe – helping the storks to fly
Treatment of Subfertility
Martin Imhof
Fertility Europe, ESHRE, Stockholm July 4, 2011
2. Regular Fertility
• conception = 25-30% per female month
healthy couples conceive
• 50% after 3 month
• 75% after 6 month
• 90% after 12 month
• medium 4 month to conceive
3. Definition of Subfertility
• reduction of male and female fertility
• no pregnancy after a period of 12
months of sexual intercourse
4. • every 5th couple has problems in
reproduction
• every 10th couple needs
medical treatment
Subfertility
9. Fertility Check
day 1 day 30
First
Consultation
Blood check
Semen analysis
8-10 days
Sonography
Hysteroscopy
Fallopian Tubes
Infection screening
Summary
Next steps1-3 days
10. Female Treatment
• Track ovulation
• Hormonale therapy
• Therapy of infections
• Ovarian stimulation
• Laparoscopy
• .....
• Less than 3-5% need IVF
11. Swan et. al. – National Institute of
environmental health sciences
•Review of 101 published studies
•Data collected 52 years (1938-1996)
Average annual decrease of
U.S. minus 1.5%/year
Europa minus 3.1%/year
Semen Quality
12. Male Subfertility
Guidelines on food fortifcation
with micronutrients
by Lindsay Allen et al. World Health Organization and
Food and Agriculture Organization of the United Nations
2006
Male factor subfertility: possible causes
and the Impact of nutritional factors
Wong WY et al., Fertil Steril 2000 73:435-442
13. Profertil Study with 120 men, Ø 35,9 a (23-58)
Intake 2x1 Capsule daily for 3 Month
L-Carnitin 440 mg
L-Arginine 250mg
Vitamin E 120 mg
Selenium 60 μg
Glutathione 80 mg
Folic-acid 800 μg
Coenzyme Q10 15 mg
Zinc 40 mg
Improvement of Male Fertility