BPSMV, South Campus , DPER ,bhainswal Kalan , Sonipat

2. • Progesterone is a steroid hormone involved in menstural
cycle, pregnancy & embryogenesis of humans.
• Progesterone is also important metabolic intermediate in
the production of other endogenous steroids.
• Plays an important role in brain function as a
neurosteroid.
• Formed in :
• Corpus leuteum : in the early pregnancy.
• Placenta : in the late pregnancy period.
• Testes
• Adrenal Cortex.

3. Pregn – 4ene – 3
, 20 – dione

4. Pregnenolone
Corpus
luteum
Placenta
Cholesterol
Progestero
nePregnant

5. Approximately 18% of serum progesterone is
bound to transcortin (Corticosteroid – binding
globulin )
 The another 80% of it is bound to serum
albumin.
The remaining 2% is free.

8. • Testosterone is a steroidal sex hormone
found in both male and female.
• Testosterone is the principle androgen
secreted by the mature testis.
• Normal young men produce about 7
mg per day .

9. • In males , testosterone is produced
by the leydig cells of the testis.
• It promotes spermatogenesis.
• To maintain functional maturation
of spermatazoa.
• To develop and maintain primary
and secondary organs.

15. • “Foye’s Principles of medicinal Chemistry “ a textbook of
medicinal chemistry , Edition 7th by “Thomas L. Lemke &
David A. Williams”.
• “Essentials of medical pharmacology” a textbook of
medical pharmacology , “seventh Edition” Page No. 282.
• www.wikipedia.org.in.
• www.ncbi.nlm.nih.gov.in
• www.mayoclinic.com
• Estrogens- advances in research and application : 2013
Edition; 21st june 2013 Page no. 4.`