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- 1. 1 3/27/2023 Acquired Immunity Hugh B. Fackrell filename : Kuby 01B7
- 2. 2 3/27/2023 Acquired Immunity: Outline Acquired vs Innate Immunity Functions of Acquired Immunity Humoral Immunity: antibody Cell Mediated Immunity Role of Macrophages Regulation of Immunity Next
- 3. 3 3/27/2023 Acquired Immunity: Definitions Acquired Immunity Antigen Immunogen Humoral Immunity Cell Mediated Immunity Next
- 4. 4 3/27/2023 Acquired Immunity: Objectives Define the following terms: Antigen, immunogen, acquired immunity, humoral immunity, cell mediated immunity Identify the cells of the acquired immune response from light or electron micrographs Identify the functions of the cells of the acquired immune reponse Next
- 5. 5 3/27/2023 Acquired Immunity Definition Acquired immunity( AKA adaptive immunity) is an altered reactivity to a specific compound after exposure to that compound Characteristics Specificity Memory Next
- 6. 6 3/27/2023 Acquired Immunity Important Features The altered reactivity will not be to all compounds, just those compounds to which the animal has been exposed The animal has a heightened specific response on second and subsequent exposures because the body ” remembers” previous contacts Next
- 7. 7 3/27/2023 Functions of Acquired Immunity Discriminate between self and non self for: Defense destruction of foreign molecules Homeostasis removal of dead or damaged cells Surveillance control of mutant or cancer cells Next
- 8. 8 3/27/2023 Acquired Immunity has Two Forms Humoral Immunity lymphocytes react INDIRECTLY on non self molecules via antibodies Cell Mediated Immunity Lymphocytes act DIRECTLY on the non self molecules Next
- 10. 10 3/27/2023 Immunogen vs Antigen ANTIGEN: combines with the products of an immune response IMMUNOGEN: triggers immunity and combines with products
- 12. 12 3/27/2023 Remember Immunogenicity is not an inherent characteristic of a molecule Immunogen MUST first be recognized as foreign by the body Next
- 13. 13 3/27/2023 Adaptive vs Innate Immunity
- 14. 14 3/27/2023 Primary vs Secondary Responses
- 16. 16 3/27/2023 Antibodies Distinguish Between Diseases measles & mumps Macromolecules proteins, complex carbohydrates Molecules amino acids, sugars Submolecular Structures D& L isomers; ortho, meta, para positions Next
- 19. 19 3/27/2023 Clonal Selection: B cells
- 20. 20 3/27/2023 Immunglobulin on B cells
- 22. 22 3/27/2023 Antibody: a Flexible mediator
- 27. 27 3/27/2023 T cell blasts: structure
- 29. 29 3/27/2023 Cell mediated clonal selection
- 31. 31 3/27/2023 T cells ANAE stain
- 36. 36 3/27/2023 Macrophages & T cells
- 37. 37 3/27/2023 T cells interacting with Macrophage
- 39. 39 3/27/2023 Macrophage mediators: CD14 & LPS receptors
- 40. 40 3/27/2023 Endotoxin induction of Macrophage mediators: direct induction
- 43. 43 3/27/2023 Range of immune responses
- 45. 45 3/27/2023 Cellular interactions during the humoral response
- 46. 46 3/27/2023 A Complete Immune Response Lymphocytes B cells T cells Macrophages critical accessory cells Complement combines with antibody to enhance destruction Next
- 48. 48 3/27/2023 Adverse effects of Immunity
- 50. 50 3/27/2023 Acquired Immunity: Questions How does clonal selection contribute to memory in the immune response? Name three feature of a secondary immune response that make it different from a primary immune response.
- 51. 51 3/27/2023 Questions(1) Interleukin 2 is a nonspecific growth factor that stimulates the growth of TH cells during the immune response. In view of this nonspecificity of IL-2, what mechanism assures that only TH cells specific for a given antigen proliferate and that all other TH cells do not proliferate
- 52. 52 3/27/2023 Questions (2) Antigen presenting cells play a role in both humoral and cell mediated immune responses Name three type af antigen presenting cells Which class of MHC molecules are expressed on the membrane of antigen presenting cells? Which lymphocytes interact eith antigen presenting cells?