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SURGICAL MANAGEMENT
FOR URINARY LITHIASIS
EXTRACORPOREAL SHOCK
WAVE LITHOTRIPSY (ESWL)
Methods | Techniques | Complications | Future Direction
METHODS AND PHYSICAL PRINCIPLES
• External source generates shock wave
directed towards patient’s body
• Propagation of linear waves, although large
amount of pressure is used – relatively weak
and only induce slight compression and
deformation of material
• Shock waves only apply sufficient strength at
the targeted part generating enough force
to fragment a stone
SHOCK WAVE
GENERATOR TYPES
• Three primary types of shock wave
generators:
• ELECTROHYDRAULIC (Spark Gap)
• ELECTROMAGNETIC
• PIEZOELECTRIC
ELECTROHYDRAULIC (SPARK GAP)
• Spherically expanding shock wave is generated by
and underwater spark discharge
• High voltage is applied to two opposing electrodes
resulting in a spark that produces a vaporization
bubble
• Bubble expands and collapse rapidly producing a
high energy pressure wave
ELECTROMAGNETIC GENERATOR
• Produce a magnetic field in either a flat plane or
around a cylinder
• Flat plane waves are focused by an acoustic lens
• Cylindrical waves are reflected by a parabolic
reflector and transformed into a spherical wave
ELECTROMAGNETIC GENERATOR
• More controllable and reproducible than
electrohydraulic generators
• Will deliver more shocks before needing servicing
• Introduce energy over a larger skin area – less pain
• Due to high energy density – increased risk of
subcapsular hematoma
PIEZOELECTRIC GENERATOR
• Produces shockwaves with directly
converging shock fronts
• Capacitor is fired to several
hundred to thousand piezoceramic
elements
• More focusing accuracy and longer
service life
• Possibility of anesthetic-free
treatment because of low-energy
density at the skin entry point
IMAGING SYSTEMS
• Three basic designs used for
stone localization:
• Fluoroscopy Alone
• Ultrasonography Alone
• Combination of both
FLUOROSCOPY ALONE
• Previous models used 2 x-ray
converters arranged at oblique
angles, 90 degrees from each other
to localize stone effectively
• To reduce cost, an adjustable C-Arm
is now used
ULTRASONOGRAPHY ALONE
• Used in several low-cost
machines – inexpensive to
manufacture and maintain
STONE FRAGMENTATION
• Initial short and steep compressive front 40
megapascals (MPa) followed by a longer, lower
amplitude negative (tensile) pressure of 10 MPa, with
the entire pulse lasting for a duration of 4
microseconds
• Ratio of 5:1 positive to negative peak pressure
• Comminution (fragmentation) results from
mechanical stressors created by 2 mechanisms
occurring simultaneously or separately:
• Directly by incident shockwave
• Indirectly by collapse of bubbles
STONE FRAGMENTATION
• Squeezing-splitting or circumferential compression – difference in
sound speed between stone and surrounding fluid
• Shear stress – generated by shear waves that develop as the shock
wave passes into the stone
• Superfocusing – amplification of stresses inside the stone because of
the geometry of that stone
STONE FRAGMENTATION
• Cavitation - formation and subsequent collapse of bubbles, oscillating
in size then collapse violently, giving rise to high temperature and
pressures
• Accumulation of damage – leads to eventual destruction of the stone
structure
BIOEFFECTS: ACUTE EXTRARENAL DAMAGE
• SWL induces acute injury in variety of extrarenal tissues
• Associated with trauma to organs such as liver and skeletal muscle
• Rare reports of colonic perforation, hepatic hematoma, splenic
rupture, pancreatitis and abdominal wall abscess
• Extrarenal vascular complications
ACUTE RENAL INJURY:
STRUCTURAL AND FUNCTIONAL
CHANGES
• Almost all post SWL patients for renal stones
demonstrate hematuria after ~200 shock waves
• Hematoma rates range from 1-20%
• Appearance of renal hematomas range from mild
contusion to a large hematoma associated with severe
bleeding necessitating BT or even angiographic
emobilization
ACUTE RENAL INJURY:
STRUCTURAL AND FUNCTIONAL CHANGES
• Probability of a subcapsular hematoma
increased 2.2 times for every 10-year increase in
the patient’s age
• Existing hypertension to be at increased risk for
the development of a perinephric hematoma
• Other risk factors: diabetes mellitus, coronary
artery disease, and obesity, all of which suggest
a link to a vascular disorder
CHRONIC RENAL INJURY:
STRUCTURAL AND FUNCTIONAL CHANGES
MECHANISM FOR TISSUE INJURY
• The violent collapse of cavitation bubbles generated by the
shock waves is primarily responsible for the cellular
changes (Cavitation concept)
TECHNIQUES TO OPTIMIZE SHOCK WAVE
LITHOTRIPSY OUTCOME
• Acoustic output and focal volume of
shock
• Number of shocks delivered and rate
• Power or voltage used
• Wider focal width – increased stone
breakage
• Use of optimal coupling medium such as
oil or gel – efficient transfer of energy
ADJUNCTS TO IMPROVE SHOCK WAVE
LITHOTRIPSY OUTCOMES
• AUA – placement of ureteral stents at
time of SWL is not recommended
• Use of MET is found to be beneficial
• Use of A-blockers for 2 weeks post SWL-
improvement in stone free rates
• Percussion diuresis and inversion (PDI)
FUTURE DIRECTION
• Visio-track (VT) locking system
• Hand held probe that allows the
lithotripter to “lock on” to the stones
during treatment
• Ultrasonic propulsion of renal calculi
• Focused ultrasound is used to expel small
stones and fragments from urinary system
PERCUTANEOUS
NEPHROLITHOTOMY (PCNL)
PATIENT PREPARATION | STONE REMOVAL | SPECIAL CONSIDERATIONS | COMPLICATIONS
PATIENT PREPARATION
• Complete history and physical exam
• Absolute contraindications
• Uncorrected coagulopathy
• Active, untreated UTI
• Percutaneous nephrostomy drain without manipulation of the calculus of associated
with obstruction of renal unit and sepsis
• Pre operative lab evaluation: CBC, electrolytes, Crea, renal function tests
PATIENT PREPARATION
• Urine culture: if with suspicion of infection
• Perioperative antibiotics can be appropriately tailored to culture specific organisms
• Preoperative imaging: Plain abdominal CT
ANTIBIOTICS
• Antibiotic prophylaxis reduces infectious complications
• Institutional antibiograms aid in selection of most appropriate perioperative
antimicrobial regimen
• Fragmentation of stones, despite sterile urine, may release preformed
bacterial endotoxins and viable bacteria – risk for sepsis
• Patients with indwelling stents
ANESTHESIA
• PCNL can be performed after the administration of general, epidural or local
anesthesia
• Local anesthesia such as lidocaine can be delivered into the access tract to
the renal capsule
• Regional anesthesia for percutaneous procedures
• High block Is necessary to eliminate all renal pain
• Distention of renal pelvis during PCNL – cause a vasovagal reaction not
prevented by regional block
ANESTHESIA
• Upper pole puncture - GA is preferred to control respiratory movement
essential to minimize pulmonary complication
• Anesthesiologist must be aware of possible pulmonary injuries (hydrothorax
and pneumothorax) – close monitoring of airway pressure, CO2 levels and
O2 saturation as well as frequent lung auscultation
• Risk of hypothermia – warming of fluids; use of patient warming devices
PATIENT POSITIONING: PRONE
• Most commonly used position
• Chest supported by either a single horizontal chest roll
across the nipple line or two vertical rolls positioned
along the mid-clavicular line
• Elevation of legs to prevent pressure injury of lower
extremities
• Arms positioned toward the head in a modified
swimmer's position
• Padding of all pressure points to prevent injury
PATIENT POSITIONING: PRONE
• Direct access to favorably located posterior renal calyces
• Upper, mid or lower pole can be accessed
• Offers ready access to proximal ureter and ins some
cases, entire collecting system
• Allows bilateral percutaneous procedure without
repositioning
• Increased pulmonary capacity
PATIENT POSITIONING:
SUPINE
• Patient is positioned with the ipsilateral side
toward the most lateral aspect of the table and
the flank elevated with a bolster or 3-liter bag of
saline underneath the lumbar fossa
• The ipsilateral arm is positioned across the chest,
and padding is applied to limit pressure to the
elbow and wrist.
PATIENT POSITIONING:
SUPINE
• Several modifications such as Galdakao-
modified supine position
• Easy access to airway
• Optimization of CP function
• Faster operative times (no repositioning)
• Radiation exposure to surgeons hands
minimized
• Surgeon can perform procedure in seated
position
CHOICE OF CALYX FOR ACCESS
• Dictated by patient positioning
• Prone – posterior calyces are most accessible
• Supine – anterior ones are preferred
UPPER POLE CALYX
• Puncture into the upper pole calyx provides the most versatile access
• This site often requires supracostal (above the 12th rib) access leading to an
increased risk for pleural morbidity
• However, if entry directly above the 12th rib (11th intercostal space) provides the
best access to the optimal calyx, then the benefit generally exceeds the risk
INTERPOLAR CALYX
• Interpolar calyceal access likely is the least versatile
• reserved only for procedures limited to the interpolar region
LOWER POLE CALYX
• Puncture into the lower pole calyx affords the surgeon ready access to the
majority of the kidney while essentially eliminating the possibility of
pulmonary morbidity with upper-pole access
• With the use of a flexible scope, access to most calyces can be achieved
IMAGE GUIDANCE FOR PUNCTURE
• Two well described methods of antegrade percutaneous access
• Eye of the needle technique (Bull’s eye)
• fluoroscopy unit directly above the patient (directed vertically) and select the desired calyx
• rotate the top of the fluoroscopic unit 30 degrees toward the operator, which brings the
fluoroscopic view approximately in line with the posterior calyces
• Triangulation technique
• inspect the kidney with the fluoroscopy unit directly above the patient to select the desired
calyx, and hold the needle in the approximate position of the desired angle of entry
• Triangulation relies on two distinct fluoroscopy unit positions to address both medial-lateral
orientation of the needle and depth.
STONE REMOVAL
• Use of physiologic solution for irrigation during PCNL to minimize dilutional
hyponatremia in event of large volume extravasation
• Use of an amplatz working sheath prevents elevated intrapelvic pressures
• Rigid nephroscopy is performed and small stones may be grasped or extracted with
stone baskets
• Larger stones require fragmentation before extraction
STONE REMOVAL
• Rigid nephroscopy is the preferred method for
stone removal
• Flexible nephroscopy may be used during PCNL to
survey the entire renal collecting system for
residual stone fragments
• Entire collecting system including the proximal
ureter should be examined systematically
STONE REMOVAL
• LASER or electrohydraulic lithotripsy are used
to fragment larger stones
• Fragments may be flushed or manipulated
into the renal pelvis – easier retrieval
• The goal of PCNL is complete or nearly
complete clearance of stone material at the
time of the primary procedure, which greatly
simplifies secondary procedures
SPECIAL SITUATIONS
• Calyceal diverticula
• Direct puncture is quite difficult because of
small size of cavity
• After successful puncture, insertion of
guidewire to renal pelvis is often difficult
• If calculi is visible on fluoroscopy, it is
preferable to puncture directly to the stone
• Direct puncture to the diverticulum allows
use of rigid instruments providing better
visualization compared to indirect
approach
HORSESHOE KIDNEY
• The lower and centrally oriented position of the kidney, the orientation of the
collecting system, and the abnormal blood supply should be taken into account
• The upper pole calyces are more posterior and lateral and are often
subcostal, providing a convenient and relatively safe route for PCNL acces
• Flexible nephroscopy also may be required to gain access to the lower medial
calyces, where stones are often found
STAGHORN CALCULI AND COMPLEX
STONES
• Goal: Stone free
• If single access tract is to be sued – upper pole
access is preferred
• Allows treatment of upper pole, renal pelvis and
lower pole using rigid nephroscope
COMPLICATIONS OF PCNL
INTRAOPERATIVE | POST OPERATIVE
COMPLICATIONS: INTRAOPERATIVE
• Patient positioning
• Decreased venous return due to compression of vena cava in prone position
• Ischemic optic neuropathy
• Injuries to cervical spine or peripheral nerves
• Duration of surgery is linked to increased risk of nerve injuries
COMPLICATIONS: INTRAOPERATIVE
• Intraoperative bleeding
• May arise from renal parenchyma or arterial or venous vessels
• Technical aspects to reduce risk: papillary puncture of targeted calyx, less angulation
of amplatz sheath and nephroscope and fluoroscopic monitoring of serial dilatation
• In cases of significant bleeding and low visibility: recommended to stop the
procedure
• Arterial bleeding - renal angiography and embolization of bleeding vessel
COMPLICATIONS: INTRAOPERATIVE
• Organ injury (lung, pleura, spleen, liver, colon)
• Pleural injury during puncture above 12th rib - hydrothorax,
pneumothorax, hemothorax, lung injury or nephropleural fistula
• Early diagnosis is crucial
• Colonic perforation – presence of fecaluria from NT tube and diarrhea
• Retraction of nephrostomy tube into the bowel (colostomy)
• Drainage of kidney with ureteral stent
• Peritonitis – immediate surgery
COMPLICATIONS: INTRAOPERATIVE
• Absorption of irrigation fluid
• Absorbed from renal parenchymal vessels or from fluid extravasation
• Postoperative electrolyte imbalance is rare
• Volume of absorbed fluid is directly related to duration of surgery
COMPLICATIONS: POST OPERATIVE
• Fever and Sepsis
• Common complication of PCNL
• Despite use of prophylactic antibiotics, 10-40% if patient still develops
post operative fever
• Preoperative microbiological evaluation and assessment of patient risk
factors are crucial to prevent post op fever and sepsis
• Timely diagnosis and management of postoperative infectious
complications are crucial for optimizing outcomes and avoiding
progression to sepsis

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ESWL AND PCNL.pptx

  • 2. EXTRACORPOREAL SHOCK WAVE LITHOTRIPSY (ESWL) Methods | Techniques | Complications | Future Direction
  • 3. METHODS AND PHYSICAL PRINCIPLES • External source generates shock wave directed towards patient’s body • Propagation of linear waves, although large amount of pressure is used – relatively weak and only induce slight compression and deformation of material • Shock waves only apply sufficient strength at the targeted part generating enough force to fragment a stone
  • 4. SHOCK WAVE GENERATOR TYPES • Three primary types of shock wave generators: • ELECTROHYDRAULIC (Spark Gap) • ELECTROMAGNETIC • PIEZOELECTRIC
  • 5. ELECTROHYDRAULIC (SPARK GAP) • Spherically expanding shock wave is generated by and underwater spark discharge • High voltage is applied to two opposing electrodes resulting in a spark that produces a vaporization bubble • Bubble expands and collapse rapidly producing a high energy pressure wave
  • 6. ELECTROMAGNETIC GENERATOR • Produce a magnetic field in either a flat plane or around a cylinder • Flat plane waves are focused by an acoustic lens • Cylindrical waves are reflected by a parabolic reflector and transformed into a spherical wave
  • 7. ELECTROMAGNETIC GENERATOR • More controllable and reproducible than electrohydraulic generators • Will deliver more shocks before needing servicing • Introduce energy over a larger skin area – less pain • Due to high energy density – increased risk of subcapsular hematoma
  • 8. PIEZOELECTRIC GENERATOR • Produces shockwaves with directly converging shock fronts • Capacitor is fired to several hundred to thousand piezoceramic elements • More focusing accuracy and longer service life • Possibility of anesthetic-free treatment because of low-energy density at the skin entry point
  • 9. IMAGING SYSTEMS • Three basic designs used for stone localization: • Fluoroscopy Alone • Ultrasonography Alone • Combination of both
  • 10. FLUOROSCOPY ALONE • Previous models used 2 x-ray converters arranged at oblique angles, 90 degrees from each other to localize stone effectively • To reduce cost, an adjustable C-Arm is now used
  • 11. ULTRASONOGRAPHY ALONE • Used in several low-cost machines – inexpensive to manufacture and maintain
  • 12. STONE FRAGMENTATION • Initial short and steep compressive front 40 megapascals (MPa) followed by a longer, lower amplitude negative (tensile) pressure of 10 MPa, with the entire pulse lasting for a duration of 4 microseconds • Ratio of 5:1 positive to negative peak pressure • Comminution (fragmentation) results from mechanical stressors created by 2 mechanisms occurring simultaneously or separately: • Directly by incident shockwave • Indirectly by collapse of bubbles
  • 13. STONE FRAGMENTATION • Squeezing-splitting or circumferential compression – difference in sound speed between stone and surrounding fluid • Shear stress – generated by shear waves that develop as the shock wave passes into the stone • Superfocusing – amplification of stresses inside the stone because of the geometry of that stone
  • 14. STONE FRAGMENTATION • Cavitation - formation and subsequent collapse of bubbles, oscillating in size then collapse violently, giving rise to high temperature and pressures • Accumulation of damage – leads to eventual destruction of the stone structure
  • 15. BIOEFFECTS: ACUTE EXTRARENAL DAMAGE • SWL induces acute injury in variety of extrarenal tissues • Associated with trauma to organs such as liver and skeletal muscle • Rare reports of colonic perforation, hepatic hematoma, splenic rupture, pancreatitis and abdominal wall abscess • Extrarenal vascular complications
  • 16. ACUTE RENAL INJURY: STRUCTURAL AND FUNCTIONAL CHANGES • Almost all post SWL patients for renal stones demonstrate hematuria after ~200 shock waves • Hematoma rates range from 1-20% • Appearance of renal hematomas range from mild contusion to a large hematoma associated with severe bleeding necessitating BT or even angiographic emobilization
  • 17. ACUTE RENAL INJURY: STRUCTURAL AND FUNCTIONAL CHANGES • Probability of a subcapsular hematoma increased 2.2 times for every 10-year increase in the patient’s age • Existing hypertension to be at increased risk for the development of a perinephric hematoma • Other risk factors: diabetes mellitus, coronary artery disease, and obesity, all of which suggest a link to a vascular disorder
  • 18. CHRONIC RENAL INJURY: STRUCTURAL AND FUNCTIONAL CHANGES
  • 19. MECHANISM FOR TISSUE INJURY • The violent collapse of cavitation bubbles generated by the shock waves is primarily responsible for the cellular changes (Cavitation concept)
  • 20. TECHNIQUES TO OPTIMIZE SHOCK WAVE LITHOTRIPSY OUTCOME • Acoustic output and focal volume of shock • Number of shocks delivered and rate • Power or voltage used • Wider focal width – increased stone breakage • Use of optimal coupling medium such as oil or gel – efficient transfer of energy
  • 21. ADJUNCTS TO IMPROVE SHOCK WAVE LITHOTRIPSY OUTCOMES • AUA – placement of ureteral stents at time of SWL is not recommended • Use of MET is found to be beneficial • Use of A-blockers for 2 weeks post SWL- improvement in stone free rates • Percussion diuresis and inversion (PDI)
  • 22. FUTURE DIRECTION • Visio-track (VT) locking system • Hand held probe that allows the lithotripter to “lock on” to the stones during treatment • Ultrasonic propulsion of renal calculi • Focused ultrasound is used to expel small stones and fragments from urinary system
  • 23. PERCUTANEOUS NEPHROLITHOTOMY (PCNL) PATIENT PREPARATION | STONE REMOVAL | SPECIAL CONSIDERATIONS | COMPLICATIONS
  • 24. PATIENT PREPARATION • Complete history and physical exam • Absolute contraindications • Uncorrected coagulopathy • Active, untreated UTI • Percutaneous nephrostomy drain without manipulation of the calculus of associated with obstruction of renal unit and sepsis • Pre operative lab evaluation: CBC, electrolytes, Crea, renal function tests
  • 25. PATIENT PREPARATION • Urine culture: if with suspicion of infection • Perioperative antibiotics can be appropriately tailored to culture specific organisms • Preoperative imaging: Plain abdominal CT
  • 26. ANTIBIOTICS • Antibiotic prophylaxis reduces infectious complications • Institutional antibiograms aid in selection of most appropriate perioperative antimicrobial regimen • Fragmentation of stones, despite sterile urine, may release preformed bacterial endotoxins and viable bacteria – risk for sepsis • Patients with indwelling stents
  • 27. ANESTHESIA • PCNL can be performed after the administration of general, epidural or local anesthesia • Local anesthesia such as lidocaine can be delivered into the access tract to the renal capsule • Regional anesthesia for percutaneous procedures • High block Is necessary to eliminate all renal pain • Distention of renal pelvis during PCNL – cause a vasovagal reaction not prevented by regional block
  • 28. ANESTHESIA • Upper pole puncture - GA is preferred to control respiratory movement essential to minimize pulmonary complication • Anesthesiologist must be aware of possible pulmonary injuries (hydrothorax and pneumothorax) – close monitoring of airway pressure, CO2 levels and O2 saturation as well as frequent lung auscultation • Risk of hypothermia – warming of fluids; use of patient warming devices
  • 29. PATIENT POSITIONING: PRONE • Most commonly used position • Chest supported by either a single horizontal chest roll across the nipple line or two vertical rolls positioned along the mid-clavicular line • Elevation of legs to prevent pressure injury of lower extremities • Arms positioned toward the head in a modified swimmer's position • Padding of all pressure points to prevent injury
  • 30. PATIENT POSITIONING: PRONE • Direct access to favorably located posterior renal calyces • Upper, mid or lower pole can be accessed • Offers ready access to proximal ureter and ins some cases, entire collecting system • Allows bilateral percutaneous procedure without repositioning • Increased pulmonary capacity
  • 31. PATIENT POSITIONING: SUPINE • Patient is positioned with the ipsilateral side toward the most lateral aspect of the table and the flank elevated with a bolster or 3-liter bag of saline underneath the lumbar fossa • The ipsilateral arm is positioned across the chest, and padding is applied to limit pressure to the elbow and wrist.
  • 32. PATIENT POSITIONING: SUPINE • Several modifications such as Galdakao- modified supine position • Easy access to airway • Optimization of CP function • Faster operative times (no repositioning) • Radiation exposure to surgeons hands minimized • Surgeon can perform procedure in seated position
  • 33. CHOICE OF CALYX FOR ACCESS • Dictated by patient positioning • Prone – posterior calyces are most accessible • Supine – anterior ones are preferred
  • 34. UPPER POLE CALYX • Puncture into the upper pole calyx provides the most versatile access • This site often requires supracostal (above the 12th rib) access leading to an increased risk for pleural morbidity • However, if entry directly above the 12th rib (11th intercostal space) provides the best access to the optimal calyx, then the benefit generally exceeds the risk
  • 35. INTERPOLAR CALYX • Interpolar calyceal access likely is the least versatile • reserved only for procedures limited to the interpolar region
  • 36. LOWER POLE CALYX • Puncture into the lower pole calyx affords the surgeon ready access to the majority of the kidney while essentially eliminating the possibility of pulmonary morbidity with upper-pole access • With the use of a flexible scope, access to most calyces can be achieved
  • 37. IMAGE GUIDANCE FOR PUNCTURE • Two well described methods of antegrade percutaneous access • Eye of the needle technique (Bull’s eye) • fluoroscopy unit directly above the patient (directed vertically) and select the desired calyx • rotate the top of the fluoroscopic unit 30 degrees toward the operator, which brings the fluoroscopic view approximately in line with the posterior calyces • Triangulation technique • inspect the kidney with the fluoroscopy unit directly above the patient to select the desired calyx, and hold the needle in the approximate position of the desired angle of entry • Triangulation relies on two distinct fluoroscopy unit positions to address both medial-lateral orientation of the needle and depth.
  • 38. STONE REMOVAL • Use of physiologic solution for irrigation during PCNL to minimize dilutional hyponatremia in event of large volume extravasation • Use of an amplatz working sheath prevents elevated intrapelvic pressures • Rigid nephroscopy is performed and small stones may be grasped or extracted with stone baskets • Larger stones require fragmentation before extraction
  • 39. STONE REMOVAL • Rigid nephroscopy is the preferred method for stone removal • Flexible nephroscopy may be used during PCNL to survey the entire renal collecting system for residual stone fragments • Entire collecting system including the proximal ureter should be examined systematically
  • 40. STONE REMOVAL • LASER or electrohydraulic lithotripsy are used to fragment larger stones • Fragments may be flushed or manipulated into the renal pelvis – easier retrieval • The goal of PCNL is complete or nearly complete clearance of stone material at the time of the primary procedure, which greatly simplifies secondary procedures
  • 41. SPECIAL SITUATIONS • Calyceal diverticula • Direct puncture is quite difficult because of small size of cavity • After successful puncture, insertion of guidewire to renal pelvis is often difficult • If calculi is visible on fluoroscopy, it is preferable to puncture directly to the stone • Direct puncture to the diverticulum allows use of rigid instruments providing better visualization compared to indirect approach
  • 42. HORSESHOE KIDNEY • The lower and centrally oriented position of the kidney, the orientation of the collecting system, and the abnormal blood supply should be taken into account • The upper pole calyces are more posterior and lateral and are often subcostal, providing a convenient and relatively safe route for PCNL acces • Flexible nephroscopy also may be required to gain access to the lower medial calyces, where stones are often found
  • 43. STAGHORN CALCULI AND COMPLEX STONES • Goal: Stone free • If single access tract is to be sued – upper pole access is preferred • Allows treatment of upper pole, renal pelvis and lower pole using rigid nephroscope
  • 45. COMPLICATIONS: INTRAOPERATIVE • Patient positioning • Decreased venous return due to compression of vena cava in prone position • Ischemic optic neuropathy • Injuries to cervical spine or peripheral nerves • Duration of surgery is linked to increased risk of nerve injuries
  • 46. COMPLICATIONS: INTRAOPERATIVE • Intraoperative bleeding • May arise from renal parenchyma or arterial or venous vessels • Technical aspects to reduce risk: papillary puncture of targeted calyx, less angulation of amplatz sheath and nephroscope and fluoroscopic monitoring of serial dilatation • In cases of significant bleeding and low visibility: recommended to stop the procedure • Arterial bleeding - renal angiography and embolization of bleeding vessel
  • 47. COMPLICATIONS: INTRAOPERATIVE • Organ injury (lung, pleura, spleen, liver, colon) • Pleural injury during puncture above 12th rib - hydrothorax, pneumothorax, hemothorax, lung injury or nephropleural fistula • Early diagnosis is crucial • Colonic perforation – presence of fecaluria from NT tube and diarrhea • Retraction of nephrostomy tube into the bowel (colostomy) • Drainage of kidney with ureteral stent • Peritonitis – immediate surgery
  • 48. COMPLICATIONS: INTRAOPERATIVE • Absorption of irrigation fluid • Absorbed from renal parenchymal vessels or from fluid extravasation • Postoperative electrolyte imbalance is rare • Volume of absorbed fluid is directly related to duration of surgery
  • 49. COMPLICATIONS: POST OPERATIVE • Fever and Sepsis • Common complication of PCNL • Despite use of prophylactic antibiotics, 10-40% if patient still develops post operative fever • Preoperative microbiological evaluation and assessment of patient risk factors are crucial to prevent post op fever and sepsis • Timely diagnosis and management of postoperative infectious complications are crucial for optimizing outcomes and avoiding progression to sepsis