1. Schmidt Rearrangement
The Schmidt reaction is the reaction of hydrazoic acid or an alkyl azide with a
carbonyl compound, alkene, or alcohol, often in the presence of a Brønsted or
Lewis acid.
The product is an amine, imine, or amide, with the expulsion of nitrogen
Applications of Schmidt Reaction
The Schmidt reaction can be applied to prepare amino acids, diamines, cyclic
amides, lactams, and tetrazole.
Each one of these compounds has a unique application.
For example, amino acids are used by the industry in the synthesis of drugs and
cosmetics
2. The acid-catalysed reaction of hydrogen azide with electrophiles, such as carbonyl
compounds, tertiary alcohols or alkenes.
After a rearrangement and extrusion of N2, amines, nitriles, amides or imines are
produced.
