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Get insights. Better health.




Jacqueline Thong
co-founder / CEO
Healthcare is not serving
the patient...
I’m not sure what to recommend for   OK, I’ll give it a try but I’ve
your increased pain... maybe you     already tried so many
can try this new drug?               different meds!
Big data... big deal
Power of secondary data lost if not used to change healthcare delivery


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How can patient data be useful?
Ubiqi provides a structured experiment framework


        DISEASE TRACKER                         PERSONALIZED
                                                  FEEDBACK


         PASSIVE MOBILE/
           DEVICE DATA


                                                   CLINICAL
                                                EFFECTIVENESS
         3RD PARTY DATA


                           Personal Discovery
                                 Engine

                                ITERATE
We power “citizen science”
through n=1 experiments

                                       A B BA

                                       AA B B



 BASELINE     SAMPLE HYPOTHESES     RANDOMIZATION     OUTCOME
                                                    AGGREGATION



  PATIENT:                        HEALTHCARE ORGANIZATIONS:
  Identify triggers               Understand patient behavior
  Understand symptoms             Analyze patient response
  Compare therapies               Compare therapies
  Report side-effects             Review safety data
Apply same framework across
multiple conditions
  pain    respiratory   gastrointestinal
We create value for many
healthcare organizations
                                             HEALTHCARE
 PHARMA
                                               IT (EMR)
                       PATIENT



PHARMACY
            PHARMACY                          DISEASE
 BENEFITS                        PROVIDERS
             CHAINS                            MGMT
  MGMT




                       PAYER
Software-as-a-Service
revenue model


     $50-100K              $1-5
     BASE SETUP      PER USER PER MONTH




        1X


     ONE-TIME FEE   GROWS WITH USER BASE
Addressable market is 63M
people in US alone

250M
AMERICANS COVERED BY HEALTH INSURANCE



125M
HAVE CHRONIC CONDITION


63M
BENEFIT FROM
SELF-MANAGING

OUR ADDRESSABLE MARKET
Ubiqi has a unique approach
                             ACTIONABLE INSIGHTS




                                             UBIQI


                  GENOMERA


PROVIDER-DRIVEN                                              PATIENT-DRIVEN
  PROTOCOLS                                                    PROTOCOLS

                                                     STUDY
                                                     CURE
                               THE
                  RINGFUL
                             CARROT
                  HEALTH




                             CONDITION TRACKING
30+ years of experience
in healthcare, technology,
and design




                            ADVISORS
                            ESTHER DYSON
Jacqueline Thong, CEO       JAYANT PARTHASARATHY, PHD
                            CHRIS ADAMS, MBA, PHD
Anshuman Sharma, CTO        EGILIUS SPIERINGS, MD, PHD
William Tang, Design Lead   MATTHEW MAMET
We have strong results
                Partnerships
From initial migraine minimum viable product:
  18K+ patients
  20% active for more than 6 months
  Positive health outcomes
!

Paying customer


Partnerships


In discussion
Go-to-market approach
                                                                     REPLICATE
                                                                     MODEL FOR
                                                                     BACK PAIN



                                      REFINE
                                   PRODUCT FOR                SCALE PLATFORM
                                     MIGRAINE                 - Prove utility beyond migraine
                                                              - Gather data
                                                              - Validate payer revenue model
                                  REFINE PLATFORM
       MIGRAINE                   - Prove clinical validity
         MVP                      - Gather data
                                  - Scale pharma model
                                  - Evaluate payer interest
MINIMUM VIABLE PRODUCT
- Prove utility to patients
- Gather data
- Evaluate pharma interest
- Validate pharma revenue model
Payers are our key target;
          first build credibility

          2013               2014               2015          2016     2017
REVENUE   $600K              $4M                $16M          $45M     $75M

           PHARMA PILOTS

                           SCALE PHARMA MODEL

                           PAYER PILOTS

                                                   SCALE PAYER MODEL
Seeking guidance in
partnership development
and $700K                          3%
                                 3%
KEY USE OF FUNDS
FOR Q12013 - Q42013
                            9%


   R&D
                          10%
   Business development
   COGS                                 55%
   Admin
   B2B Marketing           20%
   User acquisition
We envision acquisition
by a payer or disease
management company

Disease management companies


Healthcare payers
Help us create this
alternative future!
I saw that when I do yoga AND take   That’s great! Let’s
the new meds, my daily pain scores   work together to make
are 20% lower!                       that even better.
Get insights. Better health.



Jacqueline Thong
co-founder / CEO
jacqueline@ubiqihealth.com
+1 617 794 2089
www.ubiqihealth.com
Financial projections
ROI to pharma
Example: Eli Lilly / Boehringer-Ingelheim’s Tradjenta

Revenues are $3.5B annually (2.3M pts)
Adherence is 50% for oral anti-diabetic medications
Estimated $1.75B revenue lost per year
250K patients enroll in Ubiqi
At $5 per patient per month
B-I PAYS UBIQI $1.25M (1 year)

10% of users get better results
25K patients increase adherence to 75%
B-I INCREASES REVENUES BY: +$47M (1 year)
ROI to payers
Example: Aetna has 16 million subscribers

8% have asthma, costs them $2500/pt
25% enroll in Ubiqi program: 320K subscribers
At $1 per member per month...
AETNA PAYS UBIQI $3.8M (1 year)

25% of users get better results
80K subscribers reduce ER visits, hospital visits, unnecessary
prescription meds, save $500 each/yr
AETNA SAVES: $40M (1 year)
Intellectual Property
Items we anticipate constitute defensible IP:
i) process of taking structured / unstructured data and extracting
feature sets that are disease-specific and map to clinical evidence;

ii) learning engine which allows user to construct personalized
experiments that they can run to create evidence;

iii) algorithm that makes suggestions on what pieces of an
experiment the user might want to choose to ensure success based
on base-line and crowd-sourced data;

iv) algorithm that aims to increase the information contained in
unstructured patient-reported data to have stronger mapping
between evidence and outcomes

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Ubiqi Pitch Deck

  • 1. Get insights. Better health. Jacqueline Thong co-founder / CEO
  • 2. Healthcare is not serving the patient... I’m not sure what to recommend for OK, I’ll give it a try but I’ve your increased pain... maybe you already tried so many can try this new drug? different meds!
  • 3. Big data... big deal Power of secondary data lost if not used to change healthcare delivery 0 01 10 1 11 0 1 1 1 0 1 1 1 0 1 1 00 0 1 0 1 0 1 1 0 1 0 0 0 0 1 0 0 0 1 1 1 0 1 10 1 1 1 0 1 0 0 0 1 0 0 1 0 0 0 0 1 10 10 0 01 0 1 1 1 0 1 0 0 0 0 1 0 1 1 0 1 0 1
  • 4. How can patient data be useful? Ubiqi provides a structured experiment framework DISEASE TRACKER PERSONALIZED FEEDBACK PASSIVE MOBILE/ DEVICE DATA CLINICAL EFFECTIVENESS 3RD PARTY DATA Personal Discovery Engine ITERATE
  • 5. We power “citizen science” through n=1 experiments A B BA AA B B BASELINE SAMPLE HYPOTHESES RANDOMIZATION OUTCOME AGGREGATION PATIENT: HEALTHCARE ORGANIZATIONS: Identify triggers Understand patient behavior Understand symptoms Analyze patient response Compare therapies Compare therapies Report side-effects Review safety data
  • 6. Apply same framework across multiple conditions pain respiratory gastrointestinal
  • 7. We create value for many healthcare organizations HEALTHCARE PHARMA IT (EMR) PATIENT PHARMACY PHARMACY DISEASE BENEFITS PROVIDERS CHAINS MGMT MGMT PAYER
  • 8. Software-as-a-Service revenue model $50-100K $1-5 BASE SETUP PER USER PER MONTH 1X ONE-TIME FEE GROWS WITH USER BASE
  • 9. Addressable market is 63M people in US alone 250M AMERICANS COVERED BY HEALTH INSURANCE 125M HAVE CHRONIC CONDITION 63M BENEFIT FROM SELF-MANAGING OUR ADDRESSABLE MARKET
  • 10. Ubiqi has a unique approach ACTIONABLE INSIGHTS UBIQI GENOMERA PROVIDER-DRIVEN PATIENT-DRIVEN PROTOCOLS PROTOCOLS STUDY CURE THE RINGFUL CARROT HEALTH CONDITION TRACKING
  • 11. 30+ years of experience in healthcare, technology, and design ADVISORS ESTHER DYSON Jacqueline Thong, CEO JAYANT PARTHASARATHY, PHD CHRIS ADAMS, MBA, PHD Anshuman Sharma, CTO EGILIUS SPIERINGS, MD, PHD William Tang, Design Lead MATTHEW MAMET
  • 12. We have strong results Partnerships From initial migraine minimum viable product: 18K+ patients 20% active for more than 6 months Positive health outcomes ! Paying customer Partnerships In discussion
  • 13. Go-to-market approach REPLICATE MODEL FOR BACK PAIN REFINE PRODUCT FOR SCALE PLATFORM MIGRAINE - Prove utility beyond migraine - Gather data - Validate payer revenue model REFINE PLATFORM MIGRAINE - Prove clinical validity MVP - Gather data - Scale pharma model - Evaluate payer interest MINIMUM VIABLE PRODUCT - Prove utility to patients - Gather data - Evaluate pharma interest - Validate pharma revenue model
  • 14. Payers are our key target; first build credibility 2013 2014 2015 2016 2017 REVENUE $600K $4M $16M $45M $75M PHARMA PILOTS SCALE PHARMA MODEL PAYER PILOTS SCALE PAYER MODEL
  • 15. Seeking guidance in partnership development and $700K 3% 3% KEY USE OF FUNDS FOR Q12013 - Q42013 9% R&D 10% Business development COGS 55% Admin B2B Marketing 20% User acquisition
  • 16. We envision acquisition by a payer or disease management company Disease management companies Healthcare payers
  • 17. Help us create this alternative future! I saw that when I do yoga AND take That’s great! Let’s the new meds, my daily pain scores work together to make are 20% lower! that even better.
  • 18. Get insights. Better health. Jacqueline Thong co-founder / CEO jacqueline@ubiqihealth.com +1 617 794 2089 www.ubiqihealth.com
  • 20. ROI to pharma Example: Eli Lilly / Boehringer-Ingelheim’s Tradjenta Revenues are $3.5B annually (2.3M pts) Adherence is 50% for oral anti-diabetic medications Estimated $1.75B revenue lost per year 250K patients enroll in Ubiqi At $5 per patient per month B-I PAYS UBIQI $1.25M (1 year) 10% of users get better results 25K patients increase adherence to 75% B-I INCREASES REVENUES BY: +$47M (1 year)
  • 21. ROI to payers Example: Aetna has 16 million subscribers 8% have asthma, costs them $2500/pt 25% enroll in Ubiqi program: 320K subscribers At $1 per member per month... AETNA PAYS UBIQI $3.8M (1 year) 25% of users get better results 80K subscribers reduce ER visits, hospital visits, unnecessary prescription meds, save $500 each/yr AETNA SAVES: $40M (1 year)
  • 22. Intellectual Property Items we anticipate constitute defensible IP: i) process of taking structured / unstructured data and extracting feature sets that are disease-specific and map to clinical evidence; ii) learning engine which allows user to construct personalized experiments that they can run to create evidence; iii) algorithm that makes suggestions on what pieces of an experiment the user might want to choose to ensure success based on base-line and crowd-sourced data; iv) algorithm that aims to increase the information contained in unstructured patient-reported data to have stronger mapping between evidence and outcomes