4. HISTORY OF DISEASE
• First described in Japan in the 1967
medical literature by Tomisaku Kawasaki,
a Japanese pediatrician.
• In 1976 the first cases outside of Japan
were reported in Hawaii.
• Now occurs worldwide, but highest
incidence in Japan
• Has yet to be eradicated
5. SIGNS AND SYMPTOMS
• Begins with a fever lasting 5 days or more
• Other symptoms include:
• Bloodshot red eyes
• Red, dry, or cracked lips
• Swollen, red palms of the hands and the soles of the feet
• Swollen lymph nodes
• Rash
• Irritation and inflammation of the mouth, lips, and throat
SECOND STAGE
• Peeling of the skin on the hands and feet
• Joint pain
• Diarrhea
• Vomiting
• Abdominal pain
6.
7. INTERVENTIONS
• Best to start within 10 days
of fever beginning
• Include:
• High doses of IV gamma globulin
• High doses of aspirin
8.
9. PREVALENCE AND INCIDENCE RATES
• Incidence rate of 9 to 19 per 100,000
children younger than 5 years of age*
• 3277 out of 4248 hospitalizations were
for children < 5 years of age*
• 4040 out of 5447 hospitalizations were
for children < 5 years of age in 2009
*population-based and hospitalization studies as of 2013
*estimated among children younger than 18 years of age in
the United States in 2000
10. MORTALITY RATES
There are no direct deaths
associated with this disease, but
about 1 in 100 patients die from heart
problems caused by the disease.
11. INTEREST GROUPS
• Kawasaki Disease Foundation
• The only non-profit organization dedicated exclusively
to addressing Kawasaki Disease issues.
• Kawasaki Disease Research
Program
• A medical historical investigation of KD that was
initiated in the spring of 1998 to uncover useful clues
in the search for an etiology of Kawasaki disease.
12. SUMMARY
Although Kawasaki Disease is rare, it is a very serious
illness that people should be aware of. Even though death is
not associated with the disease, if left untreated long
enough heart problems could arise, therefore causing death.
What makes this disease even more dangerous is the fact
that its cause is unknown therefore no methods of
prevention are available. Therefore, the best way to protect
children from this disease is to know the signs and be able
to seek treatment in a timely manner. Hopefully, in time
research will provide answers to what causes Kawasaki
Disease and ways to prevent it.
13. REFERENCES
• Kawasaki Disease Foundation. (2014, January 1). Retrieved September 30, 2014, from
http://www.kdfoundation.org/
• Kawasaki disease: MedlinePlus Medical Encyclopedia. (2013, April 20). Retrieved
September 29, 2014, from http://www.nlm.nih.gov/medlineplus/ency/article/000989.htm
• Clute, J. (2014, September 1). Kawasaki Disease. Retrieved September 29, 2014, from
http://kidshealth.org/parent/medical/heart/kawasaki.html#
• Kawasaki Syndrome. (2013, December 13). Retrieved September 30, 2014, from
http://www.cdc.gov/kawasaki/
• Kawasaki disease. (2014, February 15). Retrieved September 30, 2014, from
http://www.mayoclinic.org/diseases-conditions/kawasaki-disease/basics/treatment/con-
20024663
• Kawasaki Disease Research Program. (n.d.). Retrieved October 1, 2014, from
http://www.emory.edu/CHCS/p_histmed_Kawasaki.htm
