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P R E S E N T E D B Y : S H A H I D H U S S A I N
P R E S E N T E D T O : M I S S M E H R E E N A B B A S I
Disease of infancy and
childhood
Kawaski disease
 Introduction
 Kawasaki disease is an acute febrile vasculitic
syndrome of early childhood
 The disorder has also been called mucocutaneous
lymph node syndrome
 Kawasaki disease was first described in 1967 by Dr
Tomisaku Kawasaki
Epidemiology
 The incidence of KD is greatest in children who live
in East Asia or are of Asian ancestry living in other
parts of the world
 In 1976, Melish et al first reported Kawasaki disease
in the United States
 higher in the Asian populations (in Japan
239.6/100,000 children < 5 years of age per year)
than in Europe, where the incidence ranges from 4.9
to 15.2/100,000/year in the same age group
Cont….
 Approximately 5000-6000 cases are reported each
year in japan
 Ontario has the highest rate of Kawasaki disease
outside of Asia, with a yearly incidence of 26.2 cases
per 100,000 population younger than 5 years
Cause
 The cause of Kawasaki disease is unknown
 It does not appear to be hereditary or contagious
 Because the illness frequently occurs in outbreaks
 It is very rare for more than one child in a family to
develop Kawasaki disease.
Sign and Symptoms
 Symptoms of Kawasaki disease include:
 A fever lasting at least 5 days
 Red eyes
 A body rash
 Swollen, red, cracked lips and tongue
 Swollen, red feet and hands
 Swollen lymph nodes in the neck
Conti….
 About a week after the fever breaks, the skin from
the fingers and toes may peel off, sometimes in large
pieces. When this happens, new, normal skin shows
below the peeling skin.
Diagnosis
 Kawasaki disease can be hard to diagnose, because
there is not a test for it
 Physicians make the diagnosis after carefully
examining a child, observing signs and symptoms
 Blood tests
 Urine tests
Treatment and Prevention
 Kawasaki disease is frequently treated in the
hospital, with a stay from a few days to a few weeks
 Some children may receive care at home without
hospitalization.
 Even though the cause of Kawasaki disease is
unknown, specific medications are known to be
beneficial
 Aspirin
 Intravenous gamma globulin
Cont…
 Kawasaki disease can't be prevented
 However, most children who have the disease
recover—usually within weeks of getting signs and
symptoms.
Kawasaki disease..

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Kawasaki disease..

  • 1.
  • 2. P R E S E N T E D B Y : S H A H I D H U S S A I N P R E S E N T E D T O : M I S S M E H R E E N A B B A S I Disease of infancy and childhood
  • 3. Kawaski disease  Introduction  Kawasaki disease is an acute febrile vasculitic syndrome of early childhood  The disorder has also been called mucocutaneous lymph node syndrome  Kawasaki disease was first described in 1967 by Dr Tomisaku Kawasaki
  • 4. Epidemiology  The incidence of KD is greatest in children who live in East Asia or are of Asian ancestry living in other parts of the world  In 1976, Melish et al first reported Kawasaki disease in the United States  higher in the Asian populations (in Japan 239.6/100,000 children < 5 years of age per year) than in Europe, where the incidence ranges from 4.9 to 15.2/100,000/year in the same age group
  • 5. Cont….  Approximately 5000-6000 cases are reported each year in japan  Ontario has the highest rate of Kawasaki disease outside of Asia, with a yearly incidence of 26.2 cases per 100,000 population younger than 5 years
  • 6. Cause  The cause of Kawasaki disease is unknown  It does not appear to be hereditary or contagious  Because the illness frequently occurs in outbreaks  It is very rare for more than one child in a family to develop Kawasaki disease.
  • 7. Sign and Symptoms  Symptoms of Kawasaki disease include:  A fever lasting at least 5 days  Red eyes  A body rash  Swollen, red, cracked lips and tongue  Swollen, red feet and hands  Swollen lymph nodes in the neck
  • 8. Conti….  About a week after the fever breaks, the skin from the fingers and toes may peel off, sometimes in large pieces. When this happens, new, normal skin shows below the peeling skin.
  • 9.
  • 10.
  • 11. Diagnosis  Kawasaki disease can be hard to diagnose, because there is not a test for it  Physicians make the diagnosis after carefully examining a child, observing signs and symptoms  Blood tests  Urine tests
  • 12. Treatment and Prevention  Kawasaki disease is frequently treated in the hospital, with a stay from a few days to a few weeks  Some children may receive care at home without hospitalization.  Even though the cause of Kawasaki disease is unknown, specific medications are known to be beneficial  Aspirin  Intravenous gamma globulin
  • 13. Cont…  Kawasaki disease can't be prevented  However, most children who have the disease recover—usually within weeks of getting signs and symptoms.